Clinical trials: Irritant Contact Dermatitis
Contact Dermatitis, Contact Dermatitis Irritant
Molecular Diagnosis of Allergic Contact Dermatitis
Allergic contact dermatitis (ACD) is a common inflammatory skin disease, affecting approximately 15-20% of the general population in industrialized countries and ranking first among occupational diseases in many European…
- Conditions
- Contact Dermatitis, Contact Dermatitis Irritant, Contact Dermatitis, Allergic
- Trial name
- MODAL (NCT06177314)
- Testing
- correlate the molecular signatures of active lesions of contact dermatitis with allergological results
- Where
- France
- Volunteers
- 80 people
- Sponsor
- Hospices Civils de Lyon
Dermatitis
Use of Low-level Laser Therapy in the Treatment of Incontinence-associated Dermatitis in the Elderly
Incontinence-associated dermatitis (IAD) is defined as skin inflammation resulting from prolonged exposure to feces and/or urine, found in individuals with urinary incontinence, fecal incontinence, or both.
- Trial name
- NCT05699122
- Testing
- Gentle intimate hygiene and skin protective barrier application - Persistent erythema with intact epidermis, Gentle intimate hygiene and skin protective barrier application - Erythema with signs of epidermis loss, Low Level Laser Therapy - Persistent erythema with intact epidermis
- Where
- Brazil
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Hospital Israelita Albert Einstein
Diaper Dermatitis
Breast Milk Versus Barrier Creams for Diaper Dermatitis in Children Aged 0-24 Months
Diaper dermatitis is a common inflammatory skin condition among children aged 0-24 months. Although commercial barrier creams are widely used, maternal breast milk has been suggested as a safe, accessible, and low-cost…
- Trial name
- NURSE-DD (NCT07633808)
- Testing
- Topical Maternal Breast Milk, Commercial Barrier Cream
- Where
- Palestinian Territories
- Volunteers
- 160 people
- Sponsor
- University of Malaya
Diaper Rash
Effects of Argan Spinosa Oil in the Treatment of Diaper Dermatitis in Infants and Toddlers
The study hypothesized that using the traditional medicinal product of Argan spinosa oil is more effective than conventional topical steroid ointment on the speed up of the healing process and alleviation the symptoms in children…
- Trial name
- NCT04210674
- Testing
- The traditional medicinal product of Argan spinosa oil
- Where
- 3 sites in Jordan
- Volunteers
- 150 people
- Sponsor
- Jordan University of Science and Technology
Diaper Rash
A Clinical Study to Assess the Efficacy and Safety of a Healing Ointment on Diaper Rash
The goal of this clinical trial is to assess the efficacy and safety of a Healing Ointment in infants 2-24 months with mild to moderate diaper rash.
- Trial name
- NCT06015217
- Testing
- "Cetaphil Healing Ointment"
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
Diaper Rash
CeraVe Cream Compared to Desitin Paste for Treating Diaper Dermatitis in Infants
This is a single-center, 1:1 randomized, double-blind, parallel-group, non-inferiority controlled trial to demonstrate non-inferiority of CeraVe Baby Diaper Rash Cream compared to Desitin Maximum Strength Original Paste when…
- Trial name
- NCT02299206
- Testing
- CeraVe Baby Diaper Rash Cream, Desitin Maximum Strength Original Paste
- Where
- 3 sites in United States
- Volunteers
- 4 people
- Sponsor
- Northwestern University
Diaper Dermatitis, Perioral Dermatitis
Effect of Cream Paste Containg Pleuran on Selected Skin Dermatoses (Neonatal Pustulosis, Diaper Dermatitis, Perioral Dermatitis).
In this multicentre, prospective clinical research conducted in outpatient healthcare facilities, the investigators studied the effect of novel cosmetic product Imunoglukan P4H® ACUTE! cream paste in children with neonatal…
- Conditions
- Diaper Dermatitis, Perioral Dermatitis, Neonatal Pustulosis, Periorificial Dermatitis
- Trial name
- ECESID (NCT07479004)
- Testing
- Cosmetic product: Imunoglukan P4H® ACUTE! cream-paste
- Where
- 15 sites in Slovakia
- Volunteers
- 110 people
- Sponsor
- Pleuran, s.r.o.
Healthy Volunteer
Safety Evaluation of KX01 Ointment 1% in Japanese Healthy Male Subjects
Skin Irritation and Phototoxicity Study of KX01 Ointment 1% in Japanese healthy male subjects
- Trial name
- NCT05245578
- Testing
- KX01 ointment 1%
- Where
- Japan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- PharmaEssentia
Allergic Contact Dermatitis
Efficacy of Baricitinib In Treatment of Delayed-Type Hypersensitivity Versus Irritant Skin Reactions in Healthy Adult Male Subjects
The treatment of allergic contact dermatitis (ACD) can be unsatisfactory, and that other skin diseases such as atopic dermatitis have an increased likelihood of ACD, improved systemic treatments are needed.
- Trial name
- NCT03945760
- Testing
- Baricitinib
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- Wright State Physicians
Diaper Rash, Diaper Dermatitis
Effect of Using Oxygen on the Diaper Dermatitis in Infants
Background: Airing the diaper area has a positive effect on dermatitis. In addition, it is reported in the literature that oxygen is effective in wound care.
- Trial name
- NCT05427760
- Testing
- Oxygen
- Where
- Turkey (Türkiye)
- Volunteers
- 103 people, healthy volunteers welcome
- Sponsor
- Istanbul University - Cerrahpasa
Sensitivity, Contact, Photosensitivity
Dermatological Assessment of Primary Dermal Irritability Accumulated, Sensitization, Photoallergy and Photosensitization of a Scar Gel
Evaluate the potential of Primary Dermal Irritability, Accumulated Dermal Irritability, Dermal Sensitization, Photoallergy and Photosensitization, of health products through the application of Patch Test, proving the safety of…
- Conditions
- Sensitivity, Contact, Photosensitivity, Phototoxicity
- Trial name
- NCT06723340
- Testing
- Scar gel
- Where
- Brazil
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Herbarium Laboratorio Botanico Ltda
Diaper Dermatitis
Evaluation of Factors Affecting Diaper Dermatitis
Diaper dermatitis is one of the most common skin problems in infants and children.It is a skin disorder in the perineal , perianal and surrounding area .It frequently occurs also in areas immediately adjacent to the diaper area .
- Trial name
- NCT04294186
- Volunteers
- 50 people
- Sponsor
- Assiut University
Diaper Rash
Infant Microbiome in Diaper Rash
The objective of this study is to evaluate the microbiome composition of infant's (9-12 month) skin experiencing diaper rash in order to determine if the onset and severity of erythema associated with diaper rash is influenced by…
- Trial name
- NCT02893501
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Kimberly-Clark Corporation
Incontinence Associated Dermatitis, Diaper Rash
Adjuvant Effect of Photobiomodulation in the Treatment of Incontinence-associated Dermatitis in Adults
Incontinence-associated dermatitis (IAD) is an inflammation of the skin that occurs as a result of urine or feces contact on the perineal or perigenital region in adults.
- Conditions
- Incontinence Associated Dermatitis, Diaper Rash, Photobiomodulation Therapy
- Trial name
- DAI (NCT05471180)
- Testing
- protective spray film, photobiomodulation therapy
- Where
- Brazil
- Sponsor
- University of Nove de Julho
Diaper Rash, UTI
Diaper Distribution in Low-Income Infants
The adverse effects of poverty at the individual, family, and community level on health outcomes for children are well-established.
- Conditions
- Diaper Rash, UTI, Depressive Symptoms, Stress
- Trial name
- NCT03425851
- Testing
- Diapers, Resources of diaper banks
- Where
- United States
- Sponsor
- Boston Medical Center
Irritant Contact Dermatitis
Prospective Single Center Randomized Double Blind Controlled Tolerability Trial of Six Hair Cleansing Conditioners
Hair cleansing product tolerability study
- Trial name
- NCT03483025
- Testing
- Skin Testing of Hair cleansing products
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Irritant Contact Dermatitis
Glycyrrhetinic Acid and Acute Irritant Dermatitis
Irritant dermatitis is one of the most common inflammatory skin disorders, caused by exposure to external substances that induce inflammation and immune activation.
- Trial name
- NCT07286487
- Testing
- SLS induced irritation, No Treatment, Low Dose Glycyrrhetinic Acid Formulation
- Where
- Croatia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Split, School of Medicine
Dermatitis, Contact, Dermatitis, Occupational
Efficacy of Glycerol, Two Topical Steroids, and a Topical Immune Modulator Against Skin Irritation
The purpose of this study is to compare the efficacy of glycerol ointment, triamcinolone acetonide ointment, clobetasol ointment and tacrolimus ointment on irritated skin in a cumulative skin irritation test model using healthy…
- Trial name
- WA+TR_1 (NCT00779792)
- Testing
- clobetasol, triamcinolone acetonide, tacrolimus
- Where
- Denmark
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Odense University Hospital
Phototoxicity
Phototoxicity of Frequently Prescribed Medicines
This pilot trial aims to study 10 selected commonly prescribed medicines with different grade of phototoxic potential. As there is no currently established way to assess phototoxic potential in a systematic and quantitative way…
- Trial name
- Phototox (NCT06710600)
- Testing
- Single oral dose of selected medicines, respectively, UVA and UVB radiation
- Where
- Austria
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Diaper Dermatitis
The Effect of Olive Oil and Centaury Oil on Rash
Diaper dermatitis is a preventable health problem. No study evaluating the efficacy of centaury oil in diaper dermatitis was found in the literature.
- Trial name
- NCT06800352
- Testing
- Control
- Where
- Turkey (Türkiye)
- Volunteers
- 45 people
- Sponsor
- Harran University