Clinical trials: Irritation; Vagina
HPV Genital Infection (Primary Condition Studied), Bacterial Vaginosis
Kinetics and Ecology of Human Papillomavirus Genital Infections in Young Women
Most genital infections by human papillomaviruses (HPV) are asymptomatic or benign and clear within a few months or years. There infections are much less studies than chronic infections, even though they represent the main…
- Conditions
- HPV Genital Infection (Primary Condition Studied), Bacterial Vaginosis, Chlamydiae Infection
- Trial name
- PAPCLEAR (NCT02946346)
- Testing
- vaginal sampling
- Where
- France
- Volunteers
- 190 people, healthy volunteers welcome
- Sponsor
- University Hospital, Montpellier
BACTERIAL VAGINOSIS
Bacterial Vaginosis Screening at IUD Insertion
A number of studies have shown a higher prevalence of BV among IUD users.13,,14 None, however, have screened women prior to inserting the IUD.
- Trial name
- NCT00802386
- Where
- Canada
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Unity Health Toronto
Vaginal Candidiasis
Ketoconazole Gel Versus Terconazole Cream for Vaginal Candidiasis
Vaginal Candidiasis is an infection caused by a yeast normally lives inside the body . Sometimes Candida can multiply and cause an infection if the environment inside the vagina changes in a way that encourages its growth.
- Trial name
- NCT03473418
- Testing
- Ketoconazole, Terconazole
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Assiut University
Vaginal Infection
Interventional Study to Evaluate the Effect of the Oral Administration of L.Plantarum on Vaginal Microbiota
Vaginal microbiota is abundantly colonized by Lactobacillus genera. When vaginal microbiota gets altered, opportunistic microorganisms may proliferate and become abundant species giving rise to dysbiosis.
- Trial name
- NCT04461782
- Testing
- Lactobacillus plantarum
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- AB Biotics, SA
Vaginal Infection, Breastmilk Collection
Evaluation of Breastmilk Microbiota as a Function for Immunity
The aim of this study is to evaluate the difference of breast milk microbiota between mothers with and without vaginal infections during pregnancy.
- Trial name
- NCT05005286
- Testing
- Past history of vaginal Infections
- Where
- Malaysia
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Universiti Sains Malaysia
Hygiene
Dermacyd PH_DETINBACK Tangerine Mix (Lactic Acid) - Safety.
The purpose of this study is to prove the safety in normal conditions of useof the product Dermacyd PH_DETINBACK Tangerine Mix (Lactic Acid).
- Trial name
- NCT00783939
- Testing
- Lactic Acid
- Where
- Brazil
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sanofi
Vaginosis, Bacterial
Pathogenesis of Bacterial Vaginosis in Women Who Have Sex With Women
The objectives of this study are to: (1) use cultivation-independent molecular methods to determine the sequence of microbiological events culminating in bacterial vaginosis (BV) among sexually active African American women who…
- Trial name
- NCT02272231
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Bacterial Vaginosis
PreFem: "What Happens to the Vaginal Microbiota When a BV Infection is Treated With Metronidazole?"
The study will assess vaginal microbiota levels before and after antibiotic treatment in females infected with Bacterial Vaginosis (BV).
- Trial name
- PreFem (NCT03187457)
- Testing
- Metronidazole, Control: no treatment
- Where
- United Kingdom
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Danisco
Allergic Rhinitis, Asthma
Integrating Targeted MedlinePlus Health Prescriptions Into Clinic Practice Workflow
The specific aim of this proposed project is to implement a standard process for integrating MedlinePlus health information prescriptions into the clinic workflow.
- Conditions
- Allergic Rhinitis, Asthma, Back Pain, Benign Prostatic Hypertrophy
- Trial name
- NCT00634608
- Testing
- Health Information Prescription
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- University of Missouri-Columbia
Vaginal Discharge, Trichomonas
Validity of Patient-Collected Wet Mounts
Purpose/Objectives: To compare wet mount findings for clue cells, yeast, trichomonads and white blood cells per high-power field in self-collected vaginal specimens, compared to clinician-collected specimens, among symptomatic…
- Conditions
- Vaginal Discharge, Trichomonas, Candidiasis, Vaginosis, Bacterial
- Trial name
- NCT02641717
- Testing
- vaginal swab
- Where
- United States
- Volunteers
- 77 people, healthy volunteers welcome
- Sponsor
- The University of Texas Health Science Center at San Antonio
Recurrent Vulvovaginal Candidiasis
Effect of a Lactobacillus Strain on the Prevention of Recurrent Vaginal Candidiasis
The objective of this study is to evaluate the efficacy of the consumption of the one probiotic strain in the prevention of new vaginal candidiasis events in women with recurrent vaginal candidiasis.
- Trial name
- NCT04639544
- Testing
- Lactobacillus strain
- Where
- Spain
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Biosearch S.A.
Bacterial Vaginosis
A Clinical Study to Determine the Safety and Efficacy of an Oral Probiotic Supplementation to Improve Bacterial Vaginosis in Females
A Preliminary Investigation of the Safety and Effectiveness of Oral Probiotics Supplementation for Enhancing Vaginal Health in Females with Mild to Moderate Bacterial Vaginosis: An Open-Label, Single-Arm, Prospective…
- Trial name
- NCT06486103
- Testing
- MetSheFlora - Vaginal Health
- Where
- India
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- NovoBliss Research Pvt Ltd
Vaginal Infection, Pregnancy Complications
Oral Probiotics to Reduce Vaginal Group B Streptococcal Colonization in Late Pregnancy
In the present study, the investigators aim to evaluate the potential of oral probiotics, containing Lactobacillus strains, to eradicate and reduce the vaginal colonization with group B Streptococcus (GBS) during pregnancy.
- Conditions
- Vaginal Infection, Pregnancy Complications, Neonatal Sepsis, GBS
- Trial name
- NCT03008421
- Testing
- Astarte® (HSO Health Care GmbH, Vienna, Austria)
- Where
- Austria
- Volunteers
- 1,058 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Threaten Preterm, Prethrem Labour
The Effects of Adjunctive Therapy With Vaginal Tablets Lactobacillus Acidophilus and a Low Dose Estriol (Gynoflor®) to Prolong Pregnancy Time in Preterm Labor, A Randomized Controlled Trial
The study aim to study The Adjunctive therapy with vaginal tablets containing Lactobacillus acidophilus KS400 and low-dose Estriol (Gynoflor®) in addition to standard tocolytic treatment administered once daily for 6 days…
- Conditions
- Threaten Preterm, Prethrem Labour, Bacterial Vaginitis
- Trial name
- NCT07344064
- Testing
- Gynoflor
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Queen Savang Vadhana Memorial Hospital, Thailand
Infection, Bacterial, Infection, Fungal
Point-of-care Tests for Bacterial Vaginosis and Candidosis
Vaginal infection in early pregnancy is associated with an increased risk of spontaneous preterm delivery and late miscarriage. Most studies presume that vaginal infections are responsible for up to 40% of preterm birth.
- Conditions
- Infection, Bacterial, Infection, Fungal, Preterm Birth
- Trial name
- NCT04287504
- Testing
- SavvyCheck Vaginal Yeast Test, OSOM BVBLUE Test
- Where
- Austria
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Medical University of Vienna
Treponema Pallidum Infection, Chlamydia Trachomatis Infection
Improving Maternal and Child Health Through Point-of-care STI Testing
The goal of this clinical trial is to learn if point-of-care tests (POCTs) for sexually transmitted infections (STIs) improve the timely treatment of syphilis, chlamydia, gonorrhea, and trichomonas in pregnant women.
- Conditions
- Treponema Pallidum Infection, Chlamydia Trachomatis Infection, Neisseria Gonorrheae Infection, Trichomonas Vaginalis Vaginitis
- Trial name
- MATCH-POINT (NCT07290439)
- Testing
- Point-of-care STI tests, Standard of care STI testing
- Where
- United States
- Volunteers
- 756 people, healthy volunteers welcome
- Sponsor
- Emory University
Bacterial Vaginosis, Candidosis Vaginal
Lacticaseibacillus Rhamnosus CA15 (DSM 33960) Strain as a New Driver in Restoring the Normal Vaginal Microbiota
The aim of the present randomized double-blind placebo-controlled trial is to evaluate the efficacy of a probiotic formulation, containing the probiotic strain Lacticaseibacillus rhamnosus CA15 (DSM 33960), in the treatment of…
- Conditions
- Bacterial Vaginosis, Candidosis Vaginal, Urinary Tract Infections
- Trial name
- NCT05796921
- Testing
- Lacticaseibacillus rhamnosus CA15 (DSM 33960) probiotic strain
- Where
- Italy
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Agnese Maria Chiara Rapisarda
Bacterial Vaginosis
Pharmacokinetic Study of DARE-BV1
Single-Center, Phase 1, Single-dose PK study of DARE-BV1 (2% clindamycin phosphate vaginal gel, 100mg) under development for the treatment of bacterial vaginosis (BV).
- Trial name
- NCT05354050
- Testing
- DARE-BV1
- Where
- United States
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Daré Bioscience, Inc.
Vulvovaginal Candidiasis
A Randomized Study Evaluating the Therapeutic Equivalence of Two Butoconazole Nitrate Vaginal Cream, 2% Formulations
This was a study that compared the efficacy and safety of a generic butoconazole nitrate vaginal cream, 2% to Gynazole-1 (butoconazole nitrate) Vaginal Cream, 2% in the treatment of vulvovaginal candidiasis caused by Candida…
- Trial name
- NCT01039584
- Testing
- Butoconazole Nitrate Vaginal Cream, Gynazole 1 vaginal cream
- Where
- United States
- Volunteers
- 611 people, healthy volunteers welcome
- Sponsor
- Padagis LLC
Vaginal Discharge, Sexually Transmitted Diseases
Point-of-care Tests for Vaginal Discharge in Nepal
The goal of this clinical trial is to examine if and how the implementation of point-of care-tests (POCT) for sexually transmitted infections in the management of abnormal vaginal discharge reduces the overtreatment with…
- Trial name
- POCT-BRA (NCT05977491)
- Testing
- Health care practitioner is informed of POCT results for CT and NG, Health care practitioner is informed about POCT result for TV and BV, addressing psycholsocial problems
- Where
- Nepal
- Volunteers
- 1,500 people, healthy volunteers welcome
- Sponsor
- Norwegian University of Science and Technology