Clinical trials: Irritation
IBS - Irritable Bowel Syndrome
Irritable Bowel Syndrome and Control Volunteers: Diet Challenge
The purpose of this study is to study the relationship between the bile acids, short chain fatty acids and bacteria within the intestines.
- Trial name
- NCT03983434
- Testing
- Inulin
- Where
- United States
- Volunteers
- 29 people, healthy volunteers welcome
- Sponsor
- Indiana University
Hygiene
Lactacyd Radiance (Lactic Acid) Prophetic Patch Test
Primay objective: To evaluate the potential of the products in eliciting adverse skin reaction.
- Trial name
- NCT00679562
- Testing
- Lactic Acid, Distilled water
- Where
- Thailand
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Sanofi
Hygiene
Dermacyd Femina (Lactic Acid) Pocket BR - Compatibility
To demonstrate the absence of irritation potential (primary dermic irritability and cumulated dermic irritability) and allergy (sensibilization) of the product Dermacyd Femina (Lactic Acid) Pocket BR.
- Trial name
- NCT00783861
- Testing
- Lactic Acid
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Sanofi
Irritable Bowel Syndrome
Effect of Hypnotherapy in Irritable Bowel Syndrome (IBS)
In this trial, the effects of two psychological interventions - i.e. hypnotherapy and relaxation training - are compared with care as usual in IBS treatment.
- Trial name
- NCT01279382
- Testing
- Hypnotherapy (HYP), Relaxation training (RT), Care as usual (CON)
- Where
- Netherlands
- Volunteers
- 112 people
- Sponsor
- Maastricht University Medical Center
Diarrhea Predominant Irritable Bowel Syndrome
Ability of Mayo Clinic High-performance Liquid Chromatography (HPLC) Method to Measure Fecal Bile Acids
The investigators' hypothesis is that therapy with Colesevelam, reduces fecal bile acid excretion in patients with Irritable Bowel Syndrome (IBS)-diarrhea with prior evidence of increased fecal 48 hour total bile acid excretion.
- Trial name
- NCT02111603
- Testing
- Colesevelam
- Where
- United States
- Volunteers
- 13 people
- Sponsor
- Mayo Clinic
Irritable Bowel Syndrome With Diarrhea
The Effects of Carbohydrates in Irritable Bowel Syndrome
Food and their components are often reported as gastrointestinal (GI) symptom triggers in patients with IBS. The current interest in dietary management in IBS, has largely focused on the negative effect of poorly absorbed and…
- Trial name
- FIBS (NCT04830410)
- Testing
- Fructan reintroduction
- Where
- Sweden
- Volunteers
- 65 people
- Sponsor
- Sahlgrenska University Hospital
Irritable Bowel Syndrome (IBS), Irritable Bowel Syndrome of Diarrhea Type (IBS-D)
Gelsectan® in the Treatment of Patients With Diarrhoea-predominant Irritable Bowel Syndrome
Irritable Bowel Syndrome (IBS) is one of the major Disorders of Gut-Brain Interaction (DGBI) and the most frequent reasons for referral to both primary care providers and gastroenterologists.IBS is not a life-threatening disease…
- Trial name
- GIANT (NCT06681012)
- Testing
- Gelsectan®
- Where
- 12 sites in Belgium, France and 2 more
- Volunteers
- 330 people
- Sponsor
- Devintec Sagl
Rheumatoid Arthritis, Diabetic Neuropathy
Basket Study (CT-100-002) to Evaluate the Effects of a DiNaMo™ Component Training
CT-100 is a platform that provides interactive, software based therapeutic components that may be used as part of a multimodal treatment in supplementary or standalone prescription or nonprescription software-based digital…
- Conditions
- Rheumatoid Arthritis, Diabetic Neuropathy, Fibromyalgia, Irritable Bowel Syndrome
- Trial name
- NCT05573685
- Testing
- DiNaMo Study App
- Where
- United States
- Volunteers
- 124 people
- Sponsor
- Click Therapeutics, Inc.
Irritable Bowel Syndrome
the Relationship Between Helicobacter Pylori Infection and Irritable Bowel Syndrome
Evaluating any possible relationship between irritable bowel syndrome occurrence and Helicobacter pylori infection
- Trial name
- NCT04847401
- Testing
- H. pylori stool antigen
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Sohag University
Irritability Associated With Autism Spectrum Disorder
A Study of KarXT + KarX-EC for Treatment of Irritability in Children and Adolescents With Autism Spectrum Disorder
The purpose of this study is to assess KarXT + KarX-EC for the treatment of irritability associated with autism in children and adolescents.
- Trial name
- NCT07285798
- Testing
- KarXT, KarX-EC
- Where
- 67 sites in United States, France and 8 more
- Volunteers
- 176 people
- Sponsor
- Bristol-Myers Squibb
IBS-C and IBS With Mixed Bowel Habits
Efficacy of Tegaserod in Relieving the Symptoms of Female Patients With Irritable Bowel Syndrome (IBS), Excluding Those With Predominant Diarrhea IBS
Recent literature has demonstrated that the group of IBS sufferers who experience mixed bowel habits may be more similar to IBS-C patients than IBS-D patients.
- Trial name
- NCT00142987
- Testing
- Tegaserod
- Volunteers
- 664 people
- Sponsor
- Novartis
Irritable Colon
Safety and Efficacy Study of GR68755 (Alosetron Hydrochloride) to Treat Severe Diarrhea-Predominant Irritable Bowel Syndrome (IBS)
This study is an exploratory study aiming (i) to obtain clinical experience of GR68755 in Japanese subjects with severe d-IBS to explore the feasibility of the next phase study and (ii) to obtain reference data for endpoints and…
- Trial name
- NCT01855711
- Testing
- GR68755 (Alosetron hydrochloride) 1 mg tablet
- Volunteers
- 32 people
- Sponsor
- GlaxoSmithKline
Irritable Bowel Syndrome
Probiotics and Irritable Bowel Syndrome
This clinical trial was conducted on 90 IBS patients, who fulfill ROME IV criteria and the IBS diagnostic questionnaire (Arabic version licensed by Rome Foundation) in Egyptair hospital outpatient clinic, Cairo, Egypt between May…
- Trial name
- NCT04572932
- Testing
- lactobacillus delbruekii
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Ain Shams University
Irritable Bowel Syndrome
Acceptability and Efficacy of Zemedy App Versus Education and Relaxation Training App for IBS
The purpose of this research is to assess if a new digital app version of a self-help intervention for Irritable Bowel Syndrome (IBS), is an acceptable and effective treatment for improving the overall quality of life in patients…
- Trial name
- NCT04665271
- Testing
- Zemedy App
- Where
- United States
- Volunteers
- 453 people
- Sponsor
- University of Pennsylvania
Celiac Disease, Irritable Bowel Syndrome
Irritable Bowel Syndrome Overlaping Celiac Disease
The goal of this prospective observational cohort stuty is to assess the prevalence of overlap irritable bowel syndrome on coeliac disease in patients on gluten-free diet.
- Conditions
- Celiac Disease, Irritable Bowel Syndrome, Overlap Syndrome
- Trial name
- IBSonCD (NCT05740306)
- Where
- Poland
- Volunteers
- 500 people
- Sponsor
- Centre of Postgraduate Medical Education
Irritable Bowel Syndrome
Ethosuximide to Treat IBS
Abdominal pain remains the most deleterious symptom for patients with irritable bowel syndrome (IBS) and is causing a significant alteration of their quality of life.
- Trial name
- IBSET (NCT02973542)
- Testing
- Ethosuximide
- Where
- France
- Volunteers
- 162 people
- Sponsor
- University Hospital, Clermont-Ferrand
Tooth Discoloration, Tooth Sensitivity
At-home Bleaching Using Clear Retainers
The aim of this project is to clinically evaluate patient satisfaction, whitening efficacy, tooth sensitivity, and gingival irritation during at-home whitening with 10% carbamide peroxide using an Essix-type retainer or a Vivera…
- Conditions
- Tooth Discoloration, Tooth Sensitivity, Gingivitis, Satisfaction, Patient
- Trial name
- NCT05835453
- Testing
- Whitening
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Universidad Rey Juan Carlos
IBS - Irritable Bowel Syndrome, Obesity
The Effect of a Probiotic Mixture in Obese Patients With Irritable Bowel Syndrome
The objective of the current study is to evaluate the effect of a probiotic mixture on the adequate relief and faecal microbiota in obese patients with irritable bowel syndrome
- Trial name
- NCT04760353
- Testing
- Probiotic mixture (OMNi-BiOTiC STRESS)
- Where
- 2 sites in Croatia
- Volunteers
- 80 people
- Sponsor
- University Hospital Rijeka
Irritable Bowel Syndrome Without Diarrhea
Exploratory Clinical Study to Evaluate the Optimal Dosage of Mosapride and Probiotics in Irritable Bowel Syndrome Without Predominant Diarrhea
The purpose of this study is to Evaluate the Optimal Dosage of Mosapride (Medirac) and Probitics in Irritable Bowel Syndrome Without Predominant Diarrhea.
- Trial name
- NCT01505777
- Testing
- Probiotics (Medirac)
- Where
- South Korea
- Volunteers
- 280 people
- Sponsor
- Hanmi Pharmaceutical Company Limited
Autistic Spectrum Disorders
TSO in Pediatric Autistic Spectrum Disorders
The primary objective of this study is to evaluate and compare the safety and efficacy of Trichuris suis ova (TSO) therapy (versus placebo) in pediatric patients with autism.
- Trial name
- TSO (NCT01734941)
- Testing
- TSO
- Where
- Israel
- Volunteers
- 9 people
- Sponsor
- Hadassah Medical Organization
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