Clinical trials: Irritation
Irritable Bowel Syndrome-like Symptoms, Crohn Disease Remission
A Prospective Trial in Patients With Crohn's Disease in Remission and Having Irritable Bowel Syndrome-like Symptoms
Crohn's disease is a chronic and complex inflammatory bowel disease affecting the gastrointestinal tract, causing symptoms like abdominal pain, diarrhea, and fatigue.
- Trial name
- Relieve (NCT06104631)
- Testing
- BK003
- Where
- 2 sites in Belgium, France
- Volunteers
- 50 people
- Sponsor
- Biokuris s.a.
Irritable Bowel Syndrome
Effects of Dietary Fibre in Irritable Bowel Syndrome (IBS)
The aim of the study is to investigate how different dietary fibre combinations affects physiological and microbiological outcomes, in addition to symptoms in those with IBS.
- Trial name
- NCT03803319
- Testing
- Fibre 1 (combined fibres), Fibre 2 (natural fibres)
- Where
- United Kingdom
- Volunteers
- 135 people
- Sponsor
- King's College London
Irritable Bowel Syndrome
Efficacy and Safety Evaluation of Fecal Microbiota Transplantation in Irritable Bowel Syndrome
Participants will be given FMT through oral capsules or nasojejunal tube once a month. After three-time treatment, participants were followed up for three months.
- Trial name
- NCT05740319
- Testing
- FMT
- Where
- China
- Volunteers
- 102 people, healthy volunteers welcome
- Sponsor
- Shanghai Zhongshan Hospital
Irritable Bowel Syndrome (IBS)
Synbiotic Supplement With Botanical Extracts for Gut Microbiota Balance in Irritable Bowel Syndrome
The goal of this clinical trial is to evaluate whether a synbiotic dietary supplement containing botanical extracts and multiple probiotic strains can improve gastrointestinal symptoms and modulate gut microbiota composition in…
- Trial name
- NCT07475299
- Testing
- Synbiotic supplement containing probiotic strains, botanical extracts, magnesium, vitamin B1, and L-theanine designed to support gut microbiota balance.
- Where
- Romania
- Volunteers
- 8 people
- Sponsor
- Iuliu Hatieganu University of Medicine and Pharmacy
Huntington Disease
Study to Evaluate Music Therapy on Irritability and Impulsivity in Patients With Huntington's Disease (MUSIC-HD)
The study is an open-label clinical trial evaluating whether music therapy combined with conventional management reduces irritability and impulsivity in 15 patients with early-stage Huntington's disease.
- Trial name
- MUSIC-HD (NCT06414967)
- Testing
- Music Intervention
- Where
- France
- Volunteers
- 15 people
- Sponsor
- Poitiers University Hospital
Irritable Bowel Syndrome (IBS), Anxiety
Anxiety and Depression in IBS: A Brain-Gut Axis Study
This study aims to understand how the gut and the brain communicate in people with Irritable Bowel Syndrome (IBS) who also experience anxiety and depression.
- Conditions
- Irritable Bowel Syndrome (IBS), Anxiety, Depression
- Trial name
- NCT07646834
- Testing
- Observational Study (No Intervention)
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Irritable Bowel Syndrome
Effects of Faecal Microbiota Transplantation in Patients With IBS
Irritable bowel syndrom (IBS) is a common chronic gastrointestinal disorder that affects 10-20% of the world population. The prevalence of IBS in Norway is between 8% and 25%.
- Trial name
- NCT03822299
- Testing
- healthy feces microbiota
- Where
- Norway
- Volunteers
- 164 people
- Sponsor
- Helse Fonna
Bipolar Disorder (BD)
Psychoeducational Psychotherapy in Adolescent Bipolar Disorder
This study evaluated the effects of psychoeducational psychotherapy (PEP) on neurocognitive functions, symptomatology, quality of life, and emotion regulation in euthymic adolescents with bipolar disorder (BD).
- Trial name
- NCT07396363
- Testing
- Psychoeducational psychotherapy (PEP)
- Where
- Turkey (Türkiye)
- Volunteers
- 32 people
- Sponsor
- Dokuz Eylul University
Functional Constipation, Irritable Bowel Syndrome
NutriPlant - Opportunities for Increasing Consumption of Local Fruits and Vegetables
The effects of different foods to normal bowel function in adult population will be investigated. A randomised controlled intervention trial will be conducted on about 120 (30 per group) adult (18-70 years) subjects with…
- Trial name
- NutriPlant (NCT06785831)
- Testing
- Psyllium, Sauerkraut, Fresh apples
- Where
- Slovenia
- Volunteers
- 120 people
- Sponsor
- Institute of Nutrition, Slovenia (Nutris)
Constipation Predominant Irritable Bowel Syndrome
A 26-Week Study to Evaluate the Efficacy and Safety of Tenapanor in IBS-C
This phase 3, 26-week, randomized, double-blind, placebo-controlled, multi-center study will evaluate the safety and efficacy of one dose of Tenapanor in subjects with constipation-predominant irritable bowel syndrome (IBS-C) as…
- Trial name
- T3MPO-2 (NCT02686138)
- Testing
- Tenapanor
- Where
- 117 sites in United States
- Volunteers
- 593 people
- Sponsor
- Ardelyx
Effect of Drug
Colonoscopic Probiotics Spray in Irritable Bowel Syndrome
Irritable bowel syndrome (IBS) is a common chronic functional disorder of the gastrointestinal (GI) tract characterized by chronic abdominal pain and altered bowel habits without organic disease.
- Trial name
- NCT05864716
- Testing
- Colonscopic probiotics spray
- Volunteers
- 66 people
- Sponsor
- National Cheng-Kung University Hospital
Irritable Bowel Syndrome
Single-center Exploratory Study of the Intestinal Microbiota in Patients Treated for Irritable Bowel Syndrome With Predominant Constipation and Methane Production
Irritable Bowel Syndrome (IBS), characterized by the Rome IV criteria, is a functional bowel disorder combining abdominal pain with changes in bowel habits and/or stool consistency.
- Trial name
- METHANOBIOTE (NCT06801184)
- Testing
- Plasma Sample, Stool Sample
- Where
- France
- Volunteers
- 40 people
- Sponsor
- Hospices Civils de Lyon
Hygiene
Dermacyd Breeze (Lactic Acid) Pocket BR - Compatibility
To demonstrate the absence of irritation potential (primary dermic irritability and cumulated dermic irritability) and allergy (sensibilization) of the product Dermacyd Breeze (Lactic Acid) Pocket BR.
- Trial name
- NCT00784121
- Testing
- Lactic Acid
- Where
- Brazil
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Sanofi
Skin Irritation
Repeat Insult Patch Test of Skin Irritation/Sensitization for Cetaphil Daily Facial Cleanser
Determine if Cetaphil Daily Facial Cleanser is a contact sensitizer or irritant to the skin
- Trial name
- NCT01888887
- Testing
- Cetaphil Daily Facial Cleanser
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Galderma R&D
IBS - Irritable Bowel Syndrome, Gut Microbiota
Effects of Continuous Treatment With Rifaximin and Probiotics on the Gut Microbiota of Patients With IBS-D
We will use the latest Rome IV criteria to recruit IBS-D patients and evaluate the effects of repeated treatment with rifaximin and sequential treatment with rifaximin and probiotics on different symptoms and quality of life.
- Trial name
- NCT04074421
- Testing
- Rifaximin, Probiotic Formula
- Where
- China
- Volunteers
- 240 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Acne Vulgaris
Evaluation of Irritation That Could be Caused by Two Facial Gels Applied to Opposite Sides of the Face.
A study to compare the skin irritation potential of two marketed gels for acne treatment, each applied to half of the face of healthy volunteers.
- Trial name
- NCT00714714
- Testing
- Adapalene Gel, Tretinoin Gel
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Bausch Health Americas, Inc.
Irritable Bowel Syndrome
Comparing Two Types of Diets on Psychological and Gastrointestinal Symptoms
This pilot study proposes to gain a better understanding of the health benefits of the popular "paleo-diet" in patients with irritable bowel syndrome (IBS) and explore underlying mechanisms of benefit.
- Trial name
- NCT03035799
- Testing
- Paleolithic diet, General Healthful Diet
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Johns Hopkins University
Allergy, Irritation
Cumulative Irritation Patch Test
A Cumulative Patch Test with a Challenge Phase is a test devised to ascertain if a chemical agent or agents have the potential to cause contact irritation or contact allergy in the skin.
- Conditions
- Allergy, Irritation, Sensitization
- Trial name
- NCT01842711
- Where
- United States
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Chattem, Inc.
Constipation, Irritable Bowel Syndrome
Cognitive and Psychiatric Effects of Linaclotide on Patients With Constipation
Irritable Bowel syndrome - constipation predominant (IBS-C) is a chronic and disabling,disorder of the gut that is characterized by abdominal pain or discomfort.
- Trial name
- NCT03342287
- Testing
- questionnaires, cognitive evaluation, Blood
- Where
- Canada
- Sponsor
- McMaster University
Endometriosis, Irritable Bowel Syndrome
Dietary Treatment of Endometriosis-related Irritable Bowel Syndrome
Many patients with endometriosis experience extra genital and abdominal symptoms as a major part of their problem. This includes gastrointestinal dysfunction with pain, urinary symptoms compatible with interstitial cystitis and…
- Conditions
- Endometriosis, Irritable Bowel Syndrome, Visceral Syndrome, Visceral Hypersensitivity
- Trial name
- NCT02924493
- Testing
- Diet low in fermentable carbohydrates (low FODMAP diet)
- Where
- Denmark
- Volunteers
- 22 people
- Sponsor
- University of Aarhus
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.