Clinical trials: Ischaemic Attack, Transient
TIA (Transient Ischemic Attack)
Transient Ischemic Attack (TIA) and Spoken Language
Transient Ischaemic Attack (also known as TIA or 'mini-stroke') affects about 46,000 people in the UK each year. It is assumed that people recover fully within 24 hours.
- Trial name
- NCT07206433
- Where
- United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Newcastle University
Ulcerative Colitis, Myocardial Infarction
Estimation of Cardiovascular Risk in Patients With Crohn's Disease and Ulcerative Colitis (PROVACI)
Inflammatory bowel diseases (IBD) are progressively increasing their prevalence worldwide. Up to half of patients may also have extraintestinal manifestation and cardiovascular diseases (CVDs) is one of the most relevant, being…
- Conditions
- Ulcerative Colitis, Myocardial Infarction, Stroke, Ischemic Heart Disease
- Trial name
- PROVACI (NCT07095634)
- Where
- Italy
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- IRCCS Policlinico S. Donato
Ischemic Stroke, Transient Ischemic Attack (TIA)
NUTRITION: Natural Tocotrienol Against Ischemic Stroke Event
A natural form of vitamin E called tocotrienol (TCT), found in many common foods such as barley, decreases stroke size in animal models.
- Trial name
- NUTRITION (NCT01578629)
- Testing
- Vitamin E tocotrienol (TCT) capsules ; Low dose Aspirin
- Where
- United States
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Andrew Slivka
Cerebrovascular Accident, Transient Ischemic Attack
E-Selectin Nasal Spray to Prevent Stroke Recurrence
This study will test the safety and effectiveness of a protein called E-selectin, given as a nasal spray, in preventing the formation of blood clots that can cause stroke.
- Trial name
- NCT00012454
- Testing
- E-Selectin nasal spray
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- National Institute of Neurological Disorders and Stroke (NINDS)
Acute Coronary Syndrome, Stroke
Florbetaben for Imaging of Vascular Amyloid
The Primary Objective is to determine if a new nuclear tracer (named 18F-Florbetaben) used with nuclear imaging (PET imaging) can detect inflamed plaque in patients with recent ACS or stroke/TIA.
- Conditions
- Acute Coronary Syndrome, Stroke, Transient Ischemic Attack, Atherosclerosis of Artery
- Trial name
- FERMATA (NCT06091319)
- Testing
- [18F]-Florbetaben PET and CT imaging
- Where
- Canada
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Apathy, Minor Stroke
Non-disabling Ischemic Cerebrovascular Event With Apathy
The burden of non-disabling ischemic cerebrovascular events (NICE) is significantly increased. However, few previous studies have focused on affective impairment after transient ischemic attack (TIA) and minor stroke.
- Conditions
- Apathy, Minor Stroke, Transient Ischemic Attack, Stroke
- Trial name
- NCT04917237
- Where
- China
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Changhai Hospital
Stroke, Cardiovascular Risk Factors
Exercise and Brain Health
The risk of stroke and vascular dementia is high in individuals who have had a prior stroke or TIA, and in those who have vascular disease risk factors, such as high blood pressure, abnormal cholesterol, diabetes or pre-diabetes.
- Conditions
- Stroke, Cardiovascular Risk Factors, Transient Ischemic Attack (TIA)
- Trial name
- EBH (NCT02626442)
- Testing
- Exercise
- Where
- United States
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Baltimore VA Medical Center
Fatigue, Stroke, Acute
Microstructure Imaging in Stroke Patients
The purpose of this study is to establish a methodological framework based on existing advanced neuroimaging technologies as a new clinical neuroimaging tool for assessment of possible affected brain connections in stroke and TIA…
- Conditions
- Fatigue, Stroke, Acute, Transient Ischemic Attack
- Trial name
- NCT04118790
- Testing
- Clinical Assessment, MRI scan
- Where
- 2 sites in Denmark
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Danish Research Centre for Magnetic Resonance
Ischemic Stroke, Transient Ischemic Attack
Efficacy of Ticagrelor Plus Aspirin in Mild Non-cardioembolic Ischemic Stroke
This is a randomized, controlled, active comparator arm, outcome assessor blind, parallel group design on 90 patient with diagnosis of ischemic stroke admitted in Bou-Ali Sina Hospital, Sari,Iran.The aim of study is assess the…
- Trial name
- TACAMINIS (NCT04738097)
- Testing
- Ticagrelor 90mg, Clopidogrel 75 mg
- Where
- 2 sites in Iran
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Mazandaran University of Medical Sciences
Abdominal Aortic Aneurysm, Coronary Heart Disease NOS
Social Deprivation and Initial Presentation of 12 Cardiovascular Diseases: a CALIBER Study
Study of heterogeneity in associations between social deprivation and the initial presentation of 12 cardiovascular diseases.
- Conditions
- Abdominal Aortic Aneurysm, Coronary Heart Disease NOS, Unheralded Corronary Death, Intracerebral Haemorrhage
- Trial name
- IP4 (NCT01937065)
- Testing
- No treatment
- Where
- United Kingdom
- Volunteers
- 1,937,360 people, healthy volunteers welcome
- Sponsor
- University College, London
Intracranial Atherosclerosis, Acute Stroke
Vessel Wall MR Imaging to Explore Sex-Differences of Intracranial Arterial Wall Changes After Suspected Stroke
Despite advances in stroke care, women continue to face worse outcomes after stroke than men. This disparity in outcomes may be related to biologic sex-differences that manifest in the development and progression of…
- Conditions
- Intracranial Atherosclerosis, Acute Stroke, Transient Ischemic Attack
- Trial name
- NCT03990545
- Where
- United States
- Volunteers
- 11 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Systemic Lupus Erythematosus
Libman-Sacks Endocarditis as a Cause of Neuropsychiatric Systemic Lupus Erythematosus
The purpose of this study is to determine whether Libman-Sacks endocarditis (inflammation of the heart valves) is the cause of neuropsychiatric manifestations (stroke, transient ischemic attacks, cognitive dysfunction, seizures…
- Trial name
- NCT00858884
- Testing
- Clinical and laboratory evaluations, transesophageal echocardiography, carotid duplex, transcranial duplex, and magnetic resonance of the brain
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of New Mexico
Stable Angina, Unstable Angina
Serum Uric Acid Levels and Onset of Cardiovascular Diseases: a CALIBER Study
Serum uric acid level is a commonly measured biomarker. The association between serum uric acid level and the risk of developing cardiovascular diseases has been observed in some studies, while others showed controversial…
- Conditions
- Stable Angina, Unstable Angina, Myocardial Infarction, Unheralded Coronary Heart Disease Death
- Trial name
- NCT03425305
- Volunteers
- 180,000 people, healthy volunteers welcome
- Sponsor
- University College, London
Stroke, Acute Stroke
Stroke and Cerebrovascular Diseases Registry
This is a single institutional registry database for the patients with stroke and cerebrovascular diseases. Stroke is the fifth leading cause of death in the United States.
- Conditions
- Stroke, Acute Stroke, Acute Brain Injury, Ischemic Stroke
- Trial name
- NCT03281590
- Where
- United States
- Volunteers
- 4,594 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Ischemic Attack, Transient
Does Positioning Effects on Early Postoperative Cognitive Dysfunction in Laparoscopic Oncological Surgery
Laparoscopic surgery is an alternative to open surgical techniques for reasons such as less blood loss,less need for transfusion, shorter discharge time.
- Trial name
- NCT04714346
- Testing
- no interventions
- Where
- Turkey (Türkiye)
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- Saglik Bilimleri Universitesi
Stroke, Ischemic, Transient Ischemic Attack
Extracellular Vesicles and Dysregulated Coagulation in the Prediction of Stroke
Annually 100,000 strokes occur, placing stroke as the largest cause of disability in the UK. 90% of strokes are preventable, leading to national focus on programmes including "The National Stroke Programme" to act on preventing…
- Conditions
- Stroke, Ischemic, Transient Ischemic Attack, Coagulation Disorder
- Trial name
- PREDICT-EV (NCT05645081)
- Where
- United Kingdom
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Cwm Taf University Health Board (NHS)
Transient Ischemic Attack
Cerebral Haemodynamics in Transient Ischaemic Attack
Adequate brain blood flow is essential for brain survival and function. Brain blood flow is kept relatively constant by a process called cerebral autoregulation (CA).
- Trial name
- NCT03886129
- Testing
- Transcranial Doppler Ultrasound (TCD)
- Where
- United Kingdom
- Volunteers
- 2 people, healthy volunteers welcome
- Sponsor
- University of Leicester