Clinical trials: Ischemia, Brain
Ischemic Stroke, Intracranial Hemorrhage
Registry of Acute Stroke Under New Oral Anticoagulants -Pilot (RASUNOA-Pilot)
The registry of acute stroke under new oral anticoagulants (RASUNOA) is a German multicenter, prospective, observational registry performed at about 50 study centers covering about 50.000 acute ischemic strokes and 6000 acute…
- Trial name
- RASUNOA (NCT01850797)
- Where
- Germany
- Volunteers
- 353 people
- Sponsor
- University Hospital Heidelberg
Ischemic Stroke, Acute
Emergency Stroke Unit for Acute Cerebrovascular Events ( ESU-ACE-D )
To compare the prognosis of patients with hyperacute ischemic stroke (arriving at the emergency department between 4.5-6 hours of symptom onset) managed in a standard stroke unit adherent to guidelines versus managed in Emergency…
- Trial name
- NCT06522282
- Testing
- Emergency Stroke Unit based on 0.23-T MRI, Standard stroke unit
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Beijing Tiantan Hospital
Dysphagia, Dysphagia, Oropharyngeal
K01 Impacts of Lingual Endurance Exercise
The goal of this clinical trial is to learn whether a tongue endurance exercise program can improve swallowing function in adults with dysphagia after a stroke.
- Conditions
- Dysphagia, Dysphagia, Oropharyngeal, Ischemic Stroke, Stroke
- Trial name
- NCT06072924
- Testing
- Isotonic Endurance Exercise
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- University of Cincinnati
Cerebral Infarction, Stroke
In the Real World Study, the Efficacy and Adverse Reactions of Ticagrelor on Ischemic Cerebrovascular Disease
This is a forward-looking, open, one-arm, and real clinical trial world. The researchers plan to recruit at least 50 qualified patients.
- Conditions
- Cerebral Infarction, Stroke, Nervous System Diseases, Ischemic Cerebrovascular Disease
- Trial name
- NCT05716646
- Volunteers
- 50 people
- Sponsor
- Qianfoshan Hospital
Ischemic Stroke
Certainty Of Stroke Symptom Onset Study
Intravenous tissue plasminogen activator (IV t-PA) is the only proven treatment of hyperacute cerebral infarction. The outcome of this treatment highly depends on the time from symptom onset to the administration of thrombolytic…
- Trial name
- COSSO (NCT01928641)
- Where
- South Korea
- Sponsor
- Asan Medical Center
Subarachnoid Hemorrhage, Aneurysmal
Shuxuening Injection for the Prevention of CVS in Patients With aSAH(SXN-CVS)
Aneurysmal subarachnoid hemorrhage (SAH) is a frequent worldwide cause for stroke with a mortality of around 30%. Worldwide, almost 500 000 patients have aneurysmal SAH annually.An incidence of 2-16 cases of spontaneous SAH per…
- Trial name
- SXN-CVS (NCT06138353)
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Xiaolin Chen, MD
Cardiovascular Diseases, Cerebrovascular Disorders
Women's Health Study (WHS): A Randomized Trial of Low-dose Aspirin and Vitamin E in the Primary Prevention of Cardiovascular Disease and Cancer
The purpose of this study is to evaluate the effects of low-dose aspirin and vitamin E in primary prevention of cardiovascular disease and cancer in apparently healthy women.
- Conditions
- Cardiovascular Diseases, Cerebrovascular Disorders, Coronary Disease, Heart Diseases
- Trial name
- WHS (NCT00000479)
- Testing
- Aspirin, Vitamin E
- Volunteers
- 39,876 people
- Sponsor
- Brigham and Women's Hospital
Stroke
Study to Assess the Safety and Effectiveness of the Penumbra System
This clinical evaluation is a prospective, single-arm, multi-center trial. The purpose of this clinical evaluation is to assess the safety and effectiveness of the Penumbra System in the revascularization of patients presenting…
- Trial name
- NCT00334061
- Testing
- Penumbra System
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- Penumbra Inc.
Acute Ischemic Stroke
Clopidogrel Plus Aspirin in Acute Ischemic Stroke Following Thrombectomy and/or Intravenous Thrombolysis (CoPrime)
Stroke is a common cause of disability. The most common type of stroke, an ischemic stroke, is caused by a blood vessel in the brain getting blocked by a clot.
- Trial name
- CoPrime (NCT06638151)
- Testing
- aspirin + clopidogrel, Aspirin
- Where
- Canada
- Volunteers
- 3 people
- Sponsor
- University of Alberta
Stroke, Practice
Smart-SABI: Digital Phenotyping of Stroke Access Barriers
This study aims to identify and quantify the non-clinical barriers (social, transport, and knowledge-based) that delay patient arrival at the hospital during an Acute Ischemic Stroke.
- Conditions
- Stroke, Practice, Healthcare Disparities, Thrombectomy
- Trial name
- Smart-SABI (NCT07257146)
- Testing
- Targeted Stroke Systems of Care Training (SABI-Guided)
- Where
- Egypt
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Middle East North Africa Stroke and Interventional Neurotherapies Organization
Acute Ischemic Stroke, Cerebrovascular Disorders
Brain, Blood And Clot or Tissue Registry And Collaboration
This is a prospective open enrollment biorepository to collect and evaluate blood and tissue collected during cerebrovascular procedures, which will then be used for the purposes of identifying biological markers, inflammatory…
- Trial name
- BACTRAC (NCT03153683)
- Testing
- Registry
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Justin Fraser
Cerebral Infarction
The Safety and Efficacy of Human Umbilical Cord Mesenchymal Stem Cells (19#iSCLife®-ACI) in the Treatment of Acute Cerebral Infarction
The purposes of the study is to determine the safety and efficacy of treating acute ischemic stroke patients with human umbilical cord mesenchymal stem cells (hUC-MSC).
- Trial name
- NCT03186456
- Testing
- Allogeneic umbilical cord mesenchymal stem cells (SCLnow 19#), Aspirin Tablet
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Sclnow Biotechnology Co., Ltd.
Stroke
Activated Protein C in Acute Stroke Trial
The purpose of this research study is to determine the safety and learn more about the dose of Activated Protein C (APC) in reducing the damage from stroke.
- Trial name
- APCAST (NCT00533546)
- Testing
- Activated Protein C
- Where
- 9 sites in United States
- Volunteers
- 12 people
- Sponsor
- University of Rochester
Ischemic Reperfusion Injury
Mechanism of Cardiac and Cerebral Function Injury Caused by Intraoperative Limb Ischemia-reperfusion
As a simple auxiliary tool for lower extremity orthopedic surgery, tourniquet can effectively reduce intraoperative bleeding and ensure the clarity of the operative field, effectively shorten the operation time and improve the…
- Trial name
- NCT05661227
- Testing
- Dexmedetomidine, 0.9% Sodium chloride, Tourniquet(Early)
- Where
- 2 sites in China
- Volunteers
- 120 people
- Sponsor
- Hebei Medical University Third Hospital
Stroke
Quality of Life After Stroke Using a Telemedicine-based Stroke Network
To study the effect of a telemedicine model of stroke care on patient-based outcomes.
- Trial name
- STROKE TeleQOL (NCT02447094)
- Testing
- Alteplase
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Thomas Jefferson University
Stroke, Ischemic
SYNCHRONISE: LVO Triage Timing and Outcome Study
The objective of this study is to evaluate the impact of Viz LVO in hospital systems with non-interventional and interventional (spoke and hub) stroke centers on the timing and outcomes of patients with suspected acute ischemic…
- Trial name
- NCT04608617
- Testing
- Viz LVO (De Novo Number DEN170073), Baseline Effectiveness Cohort
- Where
- 3 sites in United States
- Volunteers
- 600 people
- Sponsor
- Viz.ai, Inc.
Healthy, Coronary Disease
Investigation of Genetic Risk of Cardiovascular Disease in Prospective Cohort Study
Cardiovascular disease is a complex multifactorial and polygenic disorder that is thought to result from an interaction between a person's genetic make up and various environmental factors.
- Conditions
- Healthy, Coronary Disease, Myocardial Infarction, Cerebral Infarction
- Trial name
- NCT00262691
- Where
- Japan
- Volunteers
- 7,000 people
- Sponsor
- Nagoya University
Intravenous, Thrombosis
Intravenous TNK vs TPA for AIS Treatment on MSU,a Prospective Multicenter RCT
Acute ischemic stroke is one of the devastating diseases that increase hospitalization, disabilities, and deaths worldwide. Current treatment with intravenous thrombolytic agent can help reduce disabilities and improve quality of…
- Conditions
- Intravenous, Thrombosis, Acute Ischemic Stroke
- Trial name
- NCT06498323
- Testing
- tenecteplase
- Where
- Thailand
- Volunteers
- 160 people
- Sponsor
- Mahidol University
Stroke, Ischemic
Transitional Care Program to Improve Risk Factors in Stroke Survivors
The goal of this clinical trial is to evaluate whether our transitional care program helps stroke survivors better manage their risk factors for stroke to lower the risk of a repeat stroke.
- Trial name
- NCT06657235
- Testing
- Transitional Care Program
- Where
- United States
- Volunteers
- 224 people
- Sponsor
- Syntrillo, Inc
Ischemia, Reperfusion Injury
Goal-directed CPR Using Cerebral Oximetry
The proposed study is a single-center, randomized controlled pilot trial of adults who suffer in-hospital cardiac arrests. Using cerebral oxygenation and end-tidal carbon dioxide physiological targets to predict survival and…
- Trial name
- NCT04924985
- Testing
- Non-Physiological Feedback CPR, Physiological Feedback CPR
- Where
- United States
- Volunteers
- 106 people
- Sponsor
- NYU Langone Health
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