Clinical trials: Ischemia, Myocardial
Myocardial Infarction
Implementation and Validation of Telemedicine Software for the Automation of MRI Examinations of Acute Myocardial Infarctions
Validation of a telemedicine software application for an automated treatment of cardio-vascular MRI completely identical for both CHUs.
- Trial name
- TELECARD (NCT03601481)
- Volunteers
- 167 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Coronary Disease, Cardiovascular Diseases
Cardiac and Renal Disease Study (CARDS)
To examine the epidemiology of renal disease and its relationship to cardiovascular disease.
- Conditions
- Coronary Disease, Cardiovascular Diseases, Cerebrovascular Accident, Heart Failure
- Trial name
- NCT00049907
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Coronary Artery Disease
Assessment of Translesional Markers and Metabolomics
Blockages in the blood vessels of the heart are the main cause of chest pain, heart attacks, and sudden death. A cardiac catheterization, or injecting x-ray dye into the blood vessels of the heart and taking pictures, is…
- Trial name
- NCT00321139
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Emory University
Cardiovascular Diseases, Cerebrovascular Accident
Low Cholesterol and Mortality in Blacks and Women
To determine and compare the long term (thirty year) relationship of total cholesterol and mortality in Blacks and whites in a predominantly urban Charleston, South Carolina cohort and a predominantly rural Evans County, Georgia…
- Conditions
- Cardiovascular Diseases, Cerebrovascular Accident, Coronary Disease, Heart Diseases
- Trial name
- NCT00005430
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Myocardial Infarction, Unstable Angina
Exploring the Mechanism of Plaque Rupture in Acute Coronary Syndrome Using Coronary CT Angiography and Computational Fluid Dynamics II (EMERALD II) Study
The EMERALD II study is a multinational, multicenter, and retrospective study. ACS patients who underwent CCTA from 1 months to 3 years prior to the event will be retrospectively identified.
- Trial name
- EMERALD II (NCT03591328)
- Testing
- Coronary CT angiography
- Where
- South Korea
- Volunteers
- 429 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease
Coronary Artery and Coronary Artery Bypass Graft Imaging Using a Specialized Catheter and Computed Tomography
The present study relates to a new approach to coronary artery and coronary artery by-pass graft imaging, and more particularly to computed tomographic angiography following an aortic root injection of a low amount of contrast…
- Trial name
- NCT00474565
- Testing
- Placement of an aortic root pigtail catheter.
- Where
- United States
- Sponsor
- Corewell Health East
Chronic Stable Angina
Phase IIb Study of STA-2 in Patients With Chronic Stable Angina
The objective of this study is to evaluate the dose-response of three different dose levels of STA-2 (900 mg daily, 1800 mg daily and 2700 mg daily for 42 days) versus placebo in patients with chronic stable angina.
- Trial name
- NCT01239511
- Testing
- green tea polyphenols (STA-2)
- Where
- 5 sites in Taiwan
- Volunteers
- 186 people
- Sponsor
- Sinphar Pharmaceutical Co., Ltd
Myocardial Infarction, Inflammation
Effects of Oxygen Treatment on Mechanisms Involved in Ischemia-reperfusion Injury: A Pilot Study in Healthy Volunteers
Oxygen treatment is widely used in acutely ill patients. In particular, oxygen treatment is routinely used in acute coronary syndrome (ACS) patients with suspected acute myocardial infarction and variably recommended in…
- Conditions
- Myocardial Infarction, Inflammation, Acute Coronary Syndrome (ACS), Reperfusion Injury
- Trial name
- NCT02286544
- Testing
- Salmonella typhi vaccine (Typhim Vi®), Oxygen (Oxymask®), Atorvastatin
- Where
- Sweden
- Volunteers
- 36 people, healthy volunteers welcome
- Sponsor
- Karolinska Institutet
Coronary Artery Disease, High-risk Percutaneous Coronary Intervention
Early Feasibility Study of the Supira System in Patients Undergoing HRPCI
The objective of this study is to assess the feasibility and safety of the Supira System in providing temporary cardiovascular hemodynamic support in patients undergoing HRPCI.
- Conditions
- Coronary Artery Disease, High-risk Percutaneous Coronary Intervention, Interventional Cardiology
- Trial name
- NCT06087575
- Testing
- Supira System
- Where
- 4 sites in United States
- Volunteers
- 15 people
- Sponsor
- Supira Medical
Coronary Artery Disease, Coronary Disease
Optimal dRug Eluting steNts Implantation Guided By Intravascular Ultrasound and Optical coheRence tomoGraphy ORENBURG
The objective of this research is to assess the clinical results of implantation of different drug eluting stents under "aggressive" intravascular ultrasound (IVUS) guided all the way up to 24 months after operation and to…
- Conditions
- Coronary Artery Disease, Coronary Disease, Heart Diseases
- Trial name
- ORENBURG (NCT01917201)
- Testing
- IVUS-guided group, Non-IVUS group
- Where
- Russia
- Volunteers
- 1,000 people
- Sponsor
- The Orenburg Regional Clinical Hospital
Coronary Artery Disease
Notify 2: An Evaluation of the Impact of Notification of Incidental Coronary Artery Calcium on Statin Rates
The primary objective is to estimate the impact of notification of primary care provider and patient of at least moderate incidental coronary artery calcification (CAC) on a prior non-gated chest CT on statin prescription rates…
- Trial name
- NCT05394181
- Testing
- Notification
- Where
- United States
- Sponsor
- Stanford University
Coronary Disease
International Post PCI FFR Registry
The prognostic factors after a percutaneous coronary intervention (PCI) have not been comprehensively investigated. The investigators sought to develop a risk model to predict future clinical events after PCI using contemporary…
- Trial name
- NCT04012281
- Testing
- Percutaneous coronary intervention
- Volunteers
- 2,228 people
- Sponsor
- Seoul National University Hospital
Coronary Artery Disease
Carotid Atherosclerosis: MEtformin for Insulin ResistAnce Study
Hypothesis: Treatment with metformin in overweight non-diabetic individuals with coronary heart disease and on standard cardiovascular risk reducing agents including statins will have a beneficial impact on carotid artery…
- Trial name
- CAMERA (NCT00723307)
- Testing
- Metformin
- Where
- United Kingdom
- Volunteers
- 173 people
- Sponsor
- Professor Naveed Sattar
Myocardial Ischemia, Physical Exercise
Randomized Clinical Trial by Conglomerates on the Efficacy of Maintenance of Physical Exercise in Myocardial Ischemia
Main objective: To assess the efficacy of a phase III cardiac rehabilitation program (CRP), based on counseling in the maintenance of physical exercise (time of physical exercise per week) for patients with myocardial ischemia…
- Trial name
- CarPE3 (NCT04251611)
- Testing
- Maintenance of physical exercise
- Where
- Spain
- Volunteers
- 101 people
- Sponsor
- Núria Santaularia Capdevila
Cardiovascular Diseases, Coronary Artery Disease
Supporting Methods in Cardiovascular Diseases Rehabilitation
The study evaluates how various therapeutic approaches perform in addressing depression, anxiety symptoms, and stress levels among patients in the second stage of cardiac rehabilitation.
- Conditions
- Cardiovascular Diseases, Coronary Artery Disease, Mood Disorders, Depressive Symptoms
- Trial name
- NCT06241534
- Testing
- Cardiac rehabilitation, Relaxation-therapeutic recordings, Virtual reality therapy
- Where
- Poland
- Volunteers
- 45 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Myocardial Reperfusion, STEMI - ST Elevation Myocardial Infarction
Impact of Injection Pressure on Myocardial Reperfusion During Primary PCI
Percutaneous coronary intervention for myocardial infarction with ST elevation could be complicated with thrombus embolisation to the more distal segments of the culprit artery.
- Trial name
- ImPress (NCT03445364)
- Testing
- Use of different injection pressure during primary PCI
- Where
- Croatia
- Volunteers
- 100 people
- Sponsor
- University Hospital Sestre Milosrdnice
Chronic Obstructive Pulmonary Disease
Is COPD a Risk Factor for Cardiovascular Disease?
Patients with chronic obstructive pulmonary disease suffer from significant cardiovascular morbidity and mortality. This study wants to determine whether chronic obstructive pulmonary disease might be a risk factor for coronary…
- Trial name
- NCT02162095
- Where
- Switzerland
- Volunteers
- 162 people
- Sponsor
- University of Zurich
Sarcoidosis With Myocarditis, Sarcoidosis
Cell Free DNA in Cardiac Sarcoidosis
Sarcoidosis is a multisystem granulomatous disease of unknown cause that can affect any organ in the body, including the heart. Granulomatous myocarditis can lead to ventricular dysfunction and ventricular arrhythmias causing…
- Conditions
- Sarcoidosis With Myocarditis, Sarcoidosis, Healthy, ST Elevation Myocardial Infarction
- Trial name
- cfDNA in CS (NCT03858777)
- Testing
- cell free DNA
- Where
- 2 sites in United States
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Nabeel Hamzeh
Percutaneous Coronary Intervention, Antiplatelet Therapy
Discontinuation of Antiplatelet Therapy After Drug-Coated Balloon Treatment
The goal of this clinical trial is to evaluate the benefits and risks of discontinuing antiplatelet therapy on clinical outcomes in patients who previously underwent coronary intervention using a drug-coated balloon.
- Conditions
- Percutaneous Coronary Intervention, Antiplatelet Therapy, Drug-coated Balloon
- Trial name
- NCT07398001
- Testing
- Stop Antiplatelet, Continue Antiplatelet
- Where
- 7 sites in South Korea
- Volunteers
- 1,042 people
- Sponsor
- Ulsan University Hospital
Acute Coronary Syndrome, ST Elevated Myocardial Infarction
the PrEsentation, Rationale and Impact of reperFUSION for Acute Coronary Syndromes in Cape Town and the Garden Route Health District - the PERFUSION Registry
The global burden and threat of non-communicable diseases (NCDs) have become a major health challenge that undermines social and economic development throughout the world.
- Conditions
- Acute Coronary Syndrome, ST Elevated Myocardial Infarction, Non ST Elevation Myocardial Infarction, Unstable Angina
- Trial name
- PERFUSION (NCT04887571)
- Testing
- No Intervention - Observational Registry
- Where
- 4 sites in South Africa
- Volunteers
- 870 people
- Sponsor
- University of Cape Town
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