Clinical trials: Ischemia, Myocardial
Cardiogenic Shock, Heart Failure
NIVIA-Hemodynamics
This is an investigator-initiated, single-center, single-arm prospective study to compare non-invasive hemodynamic assessment using transthoracic echocardiography (TTE) and lung ultrasound (LUS) and hemodynamic assessment using…
- Conditions
- Cardiogenic Shock, Heart Failure, Shock, Hemodynamic Instability
- Trial name
- NCT06330597
- Testing
- Echocardiography and lung ultrasound
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- University Health Network, Toronto
Myocardial Infarction (MI), Acute Cardiovascular Disease
To Develop and Introduce Into Polyclinic Practice a Register of Patients with Experience of Myocardial Infarction and Acute Cerebrovascular Disease
This is a retrospective observational study using the methodology of creating medical registries. The expected number of patients included in the registry is about 2000 patients with myocardial infarction and/or ACVD of any…
- Trial name
- NCT06815913
- Where
- Belarus
- Volunteers
- 2,000 people
- Sponsor
- State Institution "Republican Scientific and Practical Center" Cardiology, Belarus
Acute Coronary Syndrome
Comparison of Short Versus 12 Months Prasugrel Plus Aspirin in Patients With Acute Coronary Syndromes Treated With Percutaneous Coronary Intervention and Everolimus-eluting Stents
The SORT OUT XII dual antiplatelet treatment (DAPT) duration trial, is a clinical randomized controlled superiority and non-inferiority trial to compare whether prasugrel alone versus prasugrel plus aspirin from month 1 to month…
- Trial name
- SORT OUT DAPT (NCT06718179)
- Testing
- Short duration of aspirin and prasugrel, Conventional duration of aspirin and prasugrel
- Where
- 3 sites in Denmark
- Volunteers
- 130 people
- Sponsor
- Odense University Hospital
Coronary Artery Disease
Computed Tomography-derived Fractional Flow Reserve vs. Angiographic Quantitative Flow Ratio in Management of Patients With Coronary Artery Disease
This is a multi-center, randomized controlled trial to compare the clinical outcomes between CT-derived fractional flow reserve (CT-FFR) guided strategy and angiography-derived quantitative flow ratio (QFR) guided strategy among…
- Trial name
- CONQUER (NCT07308496)
- Testing
- CT-FFR guided strategy, QFR guided strategy
- Volunteers
- 1,402 people
- Sponsor
- China National Center for Cardiovascular Diseases
Cardiac Ischemia
Ischemia in Patients With Non-obstructive Disease (INOCA) in Italy INOCA IT Multicenter Registry"
Prospective, interventional, multicentre, non-randomized, single-arm open-label study that aims to enroll 200 consecutive patients with suspected chronic ischemic heart disease in the absence of obstructive coronary artery…
- Trial name
- INOCAIT (NCT05164640)
- Testing
- not required
- Where
- 3 sites in Italy
- Volunteers
- 200 people
- Sponsor
- IRCCS San Raffaele
Coronary Artery Disease
Effects of Aerobic Interval Training on Fatigue Level and Functional Performance in Post Angioplasty Patients
The goal of this randomized controlled trial is to determine the effects of aerobic interval training on levels of tiredness and functional performance in post-angioplasty patients.
- Trial name
- NCT06325189
- Testing
- Aerobic Interval Training
- Where
- Pakistan
- Volunteers
- 47 people
- Sponsor
- Riphah International University
Coronary Artery Disease
Hemostasis With QuikClot® Radial® Pad Versus TR Band® After Transradial Artery Access
To evaluate the efficacy and safety of the QuikClot® Radial® pad on hemostasis after transradial access (TRA), compared to the standard of care TR Band®, to hopefully develop a safe and efficacious technique to achieve more rapid…
- Trial name
- NCT03535597
- Testing
- Quikclot Radial (QC) Pad
- Where
- United States
- Volunteers
- 355 people
- Sponsor
- Memorial Healthcare System
Stable Angina
Fractional FLow Reserve And IVUS for Clinical OUtcomes in Patients With InteRmediate Stenosis
To compare the safety and efficacy of FFR (fractional flow reserve)-guided percutaneous coronary intervention (PCI) strategy with IVUS (intravascular ultrasound [IVUS])-guided PCI in patients with intermediate coronary stenosis.
- Trial name
- FLAVOUR (NCT02673424)
- Testing
- FFR-guided stenting, IVUS-guided stenting
- Where
- 5 sites in China, South Korea
- Volunteers
- 1,700 people
- Sponsor
- Seoul National University Hospital
Cardiovascular Diseases, Heart Diseases
Mental Stress, Autonomic Function, and Heart Disease
To examine the vagal, vascular sympathetic, and mechno-structural components of baroreflex regulation in coronary artery disease (CAD) patients and healthy age-matched controls during rest and acute laboratory stress.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease
- Trial name
- NCT00005524
- Sponsor
- Hebrew SeniorLife
Angina Pectoris, Coronary Artery Disease
A Safety Study of ABI-007 for In-Stent Restenosis
This trial will treat patients with a new chemotherapeutic medicine who have undergone a successful and uncomplicated de novo stent placement in up to two native coronary arteries.
- Trial name
- NCT00093223
- Testing
- Paclitaxel Nanoparticle Albumin Bound
- Where
- United States
- Volunteers
- 76 people
- Sponsor
- Celgene
Coronary Heart Disease, Angina Pectoris
Safety Study of Kudiezi(Yueanxin,a Chinese Medicine Injection)Used in Hospitals in China
This study was advocated by institute of Basic Research in Clinical Medicine,China Academy of Chinese Medical Sciences in October 2011.
- Conditions
- Coronary Heart Disease, Angina Pectoris, Stroke
- Trial name
- NCT01781676
- Where
- China
- Volunteers
- 30,000 people
- Sponsor
- China Academy of Chinese Medical Sciences
Coronary Heart Disease, Periodontal Diseases
Expression of Trefoil Factors and Adrenomedullin in Subjects With Chronic Periodontitis and Coronary Heart Disease
To assess the demographic variables, periodontal parameters and to determine the expression of Trefoil factors 2 and 3 and Adrenomedullin in unstimulated saliva samples of periodontally healthy subjects with coronary heart…
- Trial name
- NCT04127474
- Where
- India
- Volunteers
- 75 people, healthy volunteers welcome
- Sponsor
- Meenakshi Ammal Dental College and Hospital
Coronary Heart Disease, Women's Health
Peer Support for Women With Heart Disease: Women@Heart
Women with heart disease are more likely to die or suffer another cardiac event or stroke within 5 years of an index event compared to men. They are also more likely to suffer depression and report lower quality of life.
- Trial name
- NCT03286010
- Testing
- Women@Heart Program
- Where
- Canada
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Ottawa Heart Institute Research Corporation
Coronary Heart Disease, Stable Angina Pectoris
BuMA OCT Study(A Comparative Evaluation of the Extent of Neointima Formation at 3 Months After Implantation Using OCT)
The objective of this study is a comparative evaluation of BuMA stent and of EXCEL stent in terms of the extent of neointima formation at 3 months after implantation using OCT.
- Conditions
- Coronary Heart Disease, Stable Angina Pectoris, Unstable Angina Pectoris, Silent Myocardial Ischemia
- Trial name
- NCT01752582
- Testing
- BuMA stent, EXCEL stent
- Where
- China
- Volunteers
- 80 people
- Sponsor
- Sino Medical Sciences Technology Inc.
Acute Coronary Syndromes, Heart Failure
Registry Of Acute meDical Emergencies in Brazil
Critical patients in emergency room are seriously situations that need quickly diagnosis and treatment. Different predictors of prognosis can be related with mortality and morbidity in-hospital and in long-term.
- Conditions
- Acute Coronary Syndromes, Heart Failure, Pulmonary Edema, Aortic Aneurysm, Familial Thoracic 1
- Trial name
- ROAD-Brazil (NCT02753023)
- Testing
- no intervention
- Where
- 6 sites in Brazil
- Volunteers
- 1,650 people
- Sponsor
- University of Sao Paulo General Hospital
Infection, Acute Coronary Syndrome
Association Between Levels of D-Dimer, Fibrinogen and PAI-1 in Elderly Patients With Infection and Occurrence of Cardio- and Cerebro-vascular Disease After Discharge
The association between the levels of d-dimer, fibrinogen and PAI-1 in plasma of elderly patients admitted to internal medicine departments because of infection and the occurrence of cardio- and cerebro-vascular disease after…
- Conditions
- Infection, Acute Coronary Syndrome, Cerebrovascular Disease
- Trial name
- NCT00512603
- Volunteers
- 52 people
- Sponsor
- Wolfson Medical Center
ST Elevation Myocardial Infarction
A Study of RTP-026 to Assess Safety, Tolerability and Efficacy in Patients With ST-Elevation Myocardial Infarction (STEMI)
This is an exploratory, randomized, double-blind, multicentre, placebo-controlled study of RTP-026. The study population will consist of men and women with documented evidence of ST-elevation myocardial infarction (STEMI)…
- Trial name
- NCT06465303
- Testing
- RTP-026
- Where
- Denmark
- Volunteers
- 66 people
- Sponsor
- ResoTher Pharma
Refractory Angina Pectoris
Extracorporeal Shockwave Therapy for the Treatment of Refractory Angina Pectoris
Low intensity shockwaves have been proven in animal studies to induce local growth of new blood vessels from existing ones. The hypothesis of this study is that shockwave therapy could improve the symptoms of patients with…
- Trial name
- NCT00662727
- Testing
- Cardiac Extracorporeal Shockwave Therapy generator (Cardiospec)
- Where
- Israel
- Volunteers
- 28 people
- Sponsor
- Medispec
Cardiovascular Diseases
Fujian Province Cardiovascular Diseases Study
This proposal delineates a research plan to collect blood from the patients with cardiovascular diseases for the purpose of establishing a molecular biological bank registry.
- Trial name
- FJCVD (NCT02430025)
- Volunteers
- 8,000 people, healthy volunteers welcome
- Sponsor
- Fujian Provincial Hospital
Coronary Heart Disease, Myocardial Injury
Intranasal Dexmedetomidine and Perioperative Myocardial Injury
PCI is the standard treatment for CAD, yet perioperative myocardial injury occurs frequently in nearly 40% of patients. Perioperative stress and sympathetic overactivation break myocardial oxygen balance and lead to cardiac…
- Conditions
- Coronary Heart Disease, Myocardial Injury, Myocardial Infarction, Dexmedetomidine
- Trial name
- NCT07549282
- Testing
- Intranasal Dexmedetomidine, Normal saline
- Where
- China
- Volunteers
- 140 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
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