Clinical trials: Ischemia Stroke
Ischemic Stroke
A Phase 3 Trial of Lesion Network Mapping-Guided cTBS for Motor Recovery After Acute Ischemic Stroke
This Phase 3 study will evaluate whether lesion network mapping-guided continuous theta burst stimulation (cTBS) can improve recovery after acute ischemic stroke.
- Trial name
- MASTRE-3 (NCT07645586)
- Testing
- LNM-navigated cTBS
- Where
- China
- Volunteers
- 584 people
- Sponsor
- Beijing Tiantan Hospital
Acute Ischemic Stroke, Ischemic Stroke
Zeit Alert for Stroke at Home (ZASH) Protocol
This is a single-arm, observational, feasibility study to evaluate if the Halo Alert System can be used in the future to detect stroke events in individuals at risk for stroke wearing the Halo Alert System overnight.
- Conditions
- Acute Ischemic Stroke, Ischemic Stroke, Stroke
- Trial name
- ZASH (NCT05669456)
- Testing
- Halo Alert System
- Volunteers
- 300 people
- Sponsor
- Zeit Medical, Inc.
Acute Stroke
The Bern Heart and Brain Interaction Study - Interaction Between Brain and Heart in Acute Ischemic Stroke
Acute ischemic stroke is caused by blockage of blood vessels in the brain. Blood vessels can be obstructed by several different mechanisms and identification of this cause is essential to minimize the risk of recurrence.
- Trial name
- BEHABIS (NCT03720522)
- Testing
- Short cardiovascular MRI (CMR), Adenosine-perfusion cardiovascular MRI (CMR), Blood draw
- Where
- Switzerland
- Volunteers
- 220 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Acute Ischemic Stroke
Efficacy and Safety Evaluation of iNstroke 5F Aspiration Catheter for Thrombectomy
Prospective, single-arm, multi-centre study to evaluate the efficacy and safety of the iNstroke 5F thromboaspiration catheter in patients with acute ischaemic stroke
- Trial name
- iNFLOW-5 (NCT07571954)
- Testing
- Thromboaspiration catheter
- Where
- 7 sites in France, Spain
- Volunteers
- 45 people
- Sponsor
- iVascular S.L.U.
Stroke
Alteplase in Elderly Acute Ischemic Stroke (AIS) Patients During Hospitalization
The objective of the study is to find out the in-hospital clinical outcomes among Chinese Acute Ischaemic Stroke (AIS) patients, who were treated with intravenous (IV) Recombinant Tissue Plasminogen Activator (rt-PA) within 4.5…
- Trial name
- NCT05395351
- Testing
- rt-PA
- Where
- China
- Volunteers
- 113,035 people
- Sponsor
- Boehringer Ingelheim
Stroke
Autologous Hematopoietic Stem Cell Transplantation in Ischemic Stroke
The purpose of this study is to evaluate the safety and efficacy of autologous peripheral hematopoietic stem cell transplantation in ischemic stroke.
- Trial name
- AHSCTIS (NCT01518231)
- Testing
- autologous hematopoiesis stem cell transplantation, Aspirin, Warfarin
- Where
- China
- Volunteers
- 40 people
- Sponsor
- Zhejiang Hospital
Acute Ischemic Stroke
Predictive Significance of TEG on END in Patients With Acute Ischemic Stroke
The purpose of this study is to evaluate whether Thromboelastography (TEG) parameters on admission might be predictive for early neurological deterioration in acute ischemic stroke patients, specifically for the DWI lesion…
- Trial name
- NCT03310931
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Dongguan People's Hospital
Ischemic Stroke
A Study of Survival and Outcome After Stroke
The objective of this study is to determine the natural history of acute ischemic stroke from large vessel thromboembolism in the brain.
- Trial name
- SOS (NCT01193569)
- Where
- United Kingdom
- Volunteers
- 142 people
- Sponsor
- Penumbra Inc.
Intracerebral Hemorrhage, Atrial Fibrillation (AF)
Oral Anticoagulation in Patients With Prior Deep Intracerebral Hemorrhage, Atrial Fibrillation, and Ischemic Stroke
This prospective, multicenter, randomized, open-label, blinded-endpoint trial aims to evaluate the efficacy and safety of oral anticoagulation with apixaban in patients with non-valvular atrial fibrillation, ischemic stroke, and…
- Conditions
- Intracerebral Hemorrhage, Atrial Fibrillation (AF), Ischemia Stroke
- Trial name
- OASIS-AF (NCT07609654)
- Testing
- Apixaban, No Oral Anticoagulation Strategy
- Where
- China
- Volunteers
- 852 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Brain Edema, Craniocerebral Trauma
A Comparison Between Two Techniques for Performing Decompressive Craniectomy
The purpose of this study is to compare two surgical techniques for a neurosurgical procedure used to treat cerebral edema (decompressive craniectomy): with watertight duraplasty vs.
- Conditions
- Brain Edema, Craniocerebral Trauma, Infarction, Middle Cerebral Artery
- Trial name
- NCT02594137
- Testing
- Without watertight duraplasty
- Volunteers
- 58 people
- Sponsor
- Hospital of the Restoration, Recife
Ischemic Stroke, Physical Disability
Rehabilitation Training Participated by Caregivers in Ischemic Stroke: a Randomized Controlled Trial to Test the Effect of Home-based Rehabilitation Intervention on Physical Function.
The goal of this clinical randomized control trial is to test the effect of home-based motor rehabilitation training participated by caregivers on physical function in patients with ischemic stroke ].
- Trial name
- NCT06186739
- Testing
- home-based motor rehabilitation training participated by caregivers, routine self-care
- Volunteers
- 58 people
- Sponsor
- Shantou University Medical College
Ischemic Stroke, Acute
Emergency Stroke Unit for Acute Cerebrovascular Events ( ESU-ACE-A )
To compare the door-to-needle time of patients with hyperacute ischemic stroke (within 4.5 hours after the onset of symptoms) managed in a standard stroke unit adherent to guidelines versus managed in Emergency Stroke Unit (a new…
- Trial name
- NCT06492239
- Testing
- Emergency Stroke Unit based on 0.23-T MRI, Standard stroke unit adherent to guidelines
- Where
- China
- Volunteers
- 218 people
- Sponsor
- Beijing Tiantan Hospital
Acute Ischemic Stroke
Anisodine Hydrobromide for Patients With Acute Ischemic Stroke Undergoing Endovascular Therapy (HEAL-2)
This phase 2, multicenter, randomized, double-blind, placebo-controlled trial will evaluate the efficacy and safety of anisodine hydrobromide in patients with acute ischemic stroke undergoing endovascular thrombectomy.
- Trial name
- NCT07800572
- Testing
- Anisodine Hydrobromide
- Where
- 13 sites in China
- Volunteers
- 204 people
- Sponsor
- Capital Medical University
Ischemic Stroke
Assessing the Safety and Effectiveness of a Neurological Thrombectomy Medical Device for Acute Ischemic Stroke
The Jacobs Institute is participating in a Sponsor Investigator study designed to collect prospective clinical evidence to evaluate the use of a neurological thrombectomy device for clot retrieval in acute ischemic patients
- Trial name
- NCT05074186
- Testing
- neurological thrombectomy device is an investigational device.
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- Jacobs institute
Ischaemic Stroke, Carotid Endarterectomy
Carotid Endarterectomy Versus Stenting in Patients With Acute Stage of Ischemic Stroke.
The objective of this clinical trial is to compare immediate and long-term results of carotid endarterectomy and carotid stenting in acute period of ischemic stroke.
- Conditions
- Ischaemic Stroke, Carotid Endarterectomy, Carotid Stenting
- Trial name
- NCT07083986
- Testing
- Carotid Artery Stent Placement, carotid endarterectomy
- Where
- Russia
- Volunteers
- 50 people
- Sponsor
- Pirogov Russian National Research Medical University
Ischemic Stroke
The Effects of tDCS Combined With Balance Training on Postural Control in Chronic Stroke Patients
Purpose: The incidence of stroke in low-to-middle income countries is increasing .Balance impairment and falling negatively impact function of stroke patients.
- Trial name
- NCT02209922
- Testing
- Transcranial direct current stimulation (tDCS)
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Shahid Beheshti University of Medical Sciences
Ischemic Attack, Transient, Stroke
Systematic Follow up of Drug Treatment by Pharmacists in Secondary Prevention After Transient Ischemic Attack
Use of drugs is an important factor in secondary prophylaxis after transient ischemic attack (TIA), but studies show that adherence to the prescribed drugs is often poor.
- Trial name
- NCT02089074
- Testing
- Drug use counselling
- Where
- 6 sites in Norway
- Volunteers
- 265 people
- Sponsor
- Norwegian University of Science and Technology
Stroke, Transient Ischemic Attack
Copeptin for Risk Stratification in Acute Stroke Patients: the CoRisk Study
Prospective observational multicenter study to evaluate copeptin as a prognostic marker in patients with an acute cerebrovascular event.
- Trial name
- CoRisk (NCT00878813)
- Testing
- Sampling of 15ml blood, Blood-Sampling
- Where
- 4 sites in Germany, Switzerland
- Volunteers
- 1,102 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
Ischemic Stroke
A Study Of Vagus Nerve Stimulation (VNS) With Mobility Training For Gait Recovery After Chronic Ischemic Stroke
The purpose of this study is to evaluate the safety, feasibility, and efficacy of vagus nerve stimulation (VNS) paired with mobility training to improve lower extremity function and gait in individuals with chronic ischemic…
- Trial name
- NCT07291024
- Testing
- Vagus nerve stimulation (VNS) paired with mobility training
- Where
- United States
- Volunteers
- 20 people
- Sponsor
- Mayo Clinic
Acute Stroke
Evaluating the Therapeutic Effect of Acupuncture on Acute Ischemic Stroke Patients
The investigators design a randomized, single blinded, control study to evaluate the therapeutic effect of acupuncture in acute ischemic stroke patients:
- Trial name
- NCT02210988
- Testing
- acupuncture
- Volunteers
- 38 people
- Sponsor
- Cathay General Hospital