Clinical trials: Ischemic
Stroke, Stroke, Ischemic
Behavioral Activation for Post-Stroke Sedentary Behavior Using Telehealth
Adults with stroke-related disability spend more time sedentary than adults without stroke-related disability, which places them at risk for poor cardiovascular health outcomes.
- Conditions
- Stroke, Stroke, Ischemic, Stroke Hemorrhagic
- Trial name
- teleABLE (NCT05029284)
- Testing
- teleABLE
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- University of Minnesota
Diabetes Mellitus, Heart Failure
Nt-proBNP Guided Primary Prevention of CV Events in Diabetic Patients
Increased levels of NT-proBNP are known to increase the risk of cardiac events in diabetic patients. The other way around, patients with normal values have an excellent prognosis on short-term.
- Conditions
- Diabetes Mellitus, Heart Failure, Coronary Artery Disease
- Trial name
- PONTIAC (NCT00562952)
- Testing
- Telmisartan, Bisoprolol
- Where
- 2 sites in Austria
- Volunteers
- 300 people
- Sponsor
- Medical University of Vienna
Acute Myocardial Infarction (AMI)
Artificial Intelligence Scalable Solution for ST Myocardial Infarction
The ASSIST clinical study is an observational, multicenter study to assess the performance of a cloud-based and AI-powered electrocardiogram (ECG) analysis platform, named Willem™, developed to detect Acute Myocardial Infarction…
- Trial name
- ASSIST (NCT06939738)
- Where
- 5 sites in Portugal, Spain
- Volunteers
- 489 people
- Sponsor
- Idoven 1903 S.L.
Myocardial Reperfusion Injury, Hypoxia
Effects of Hypoxic-hyperoxic Preconditioning in Cardio-surgical Patients
Coronary artery bypass grafting (CABG) with cardiopulmonary bypass is a common surgical therapy for patients suffering from coronary artery diseases.
- Conditions
- Myocardial Reperfusion Injury, Hypoxia, Hyperoxia, Coronary Artery Disease
- Trial name
- NCT05354648
- Testing
- Hypoxic-hyperoxic preconditioning
- Volunteers
- 120 people
- Sponsor
- Alexander Averyanov
Myocardial Infarction, Death, Sudden, Cardiac
Effect of High Dose Fish Oil Supplementation After Recent Heart Attack Using Magnetic Resonance Imaging
Doctors use magnetic resonance imaging (MRI) to obtain detailed pictures of the inside of the body. This study will evaluate a new MRI technique in people who have recently had a heart attack.
- Trial name
- OmegaREMODEL (NCT00729430)
- Testing
- Omega-3 Fatty Acids (Fish Oil Supplements)
- Where
- United States
- Volunteers
- 358 people
- Sponsor
- Brigham and Women's Hospital
Chronic Coronary Artery Disease
Contribution of the Pharmacological Profile of the A2A Receptor to Adenosine in the Diagnosis of Myocardial Ischemia
The chronic coronary artery disease could be detected by a drop in the expression of A2A receptors to adenosine, while high values of the KD / EC50 ratio are a sign of coronary ischemia.
- Trial name
- RIMACI (NCT04640844)
- Testing
- blood sample
- Where
- France
- Volunteers
- 170 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Hypoxic-Ischemic Encephalopathy, Post-Cardiorespiratory Arrest Coma
Cerebral Oxymetry and Neurological Outcome in Therapeutic Hypothermia
This study is designed to assess the effect of cerebral oxygen saturation as an early predictor of neurological outcomes in patients undergoing therapeutic hypothermia after cardiac arrest
- Conditions
- Hypoxic-Ischemic Encephalopathy, Post-Cardiorespiratory Arrest Coma, Cardiac Arrest
- Trial name
- NCT03024021
- Testing
- Near-infrared spectroscopy (NIRS) (INVOS®, Covidien)
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Tepecik Training and Research Hospital
Stroke Rehabilitation
Digital Interactive Technologies in Rehabilitation of Post-sroke Patients With Impaired Fine Function of the Hand
The aim of the study is to investigate the efficacy and safety of digital interactive technology with artificial intelligence and biofeedback Smart glove "SensoRehab" for restoration of in-hand manipulation in patients with…
- Trial name
- NCT05214521
- Testing
- digital interactive technology Smart glove "SensoRehab"
- Where
- Russia
- Volunteers
- 30 people
- Sponsor
- Moscow Scientific and Practical Center of Medical Rehabilitation, Restorative and Sports Medicine
Coronary Artery Diseases
BIOTRONIK - BIOFLOW-III Registry French Satellite
For the majority of Coronary Artery Disease (CAD) treatment with Percutaneous Transluminal Coronary Angioplasty (PTCA) provides high initial procedure success.
- Trial name
- NCT02273648
- Testing
- Drug Eluting Stent (DES)
- Where
- 50 sites in France
- Volunteers
- 1,000 people
- Sponsor
- Biotronik France
Ischemic Stroke, Hemoadsorption
Hemoadsorption for Severe Ischemic Stroke
This is a multicenter, randomized-controlled, open-label, blinded endpoint clinical trial that aims to evaluate the efficacy and safety of hemoadsorption for severe ischemic stroke
- Trial name
- NCT07127484
- Testing
- Hemoadsorption
- Where
- China
- Volunteers
- 116 people
- Sponsor
- First Affiliated Hospital of Wannan Medical College
Coronary Heart Disease
Influencing Factors of the Diagnostic Accuracy of Novel Coronary Functional Evaluation Methods
In this study, patients were retrospectively included, univariate and multivariate analysis of factors affecting their diagnosis inconsistencies was performed, and a new diagnostic model was constructed by logistic regression.
- Trial name
- NCT06178133
- Volunteers
- 500 people
- Sponsor
- Peking University Third Hospital
Atherosclerosis, Cardiovascular Diseases
Nutritional Determinants of Cardiovascular Disease
To define the role of nutritional and dietary variables in determining atherogenic traits and morbidity and mortality due to coronary heart disease as observed in the Framingham Heart Study cohort and the Framingham Offspring…
- Conditions
- Atherosclerosis, Cardiovascular Diseases, Coronary Disease, Heart Diseases
- Trial name
- NCT00005247
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Acute Ischemic Stroke
Single Ascending Dose Safety and Tolerability of NTS-104 Healthy Adults
NTS-104 TRIS will be administered as a single intravenous dose to healthy subjects at doses of 0.8, 4, 8 and 16 mg/kg in 4 Cohorts.
- Trial name
- NCT05547438
- Testing
- NTS-104 TRIS
- Where
- United States
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- NeuroTrauma Sciences, LLC
Coronary Artery Aneurysm
Coronary Artery Aneurysm Registry
International registry gathering patients with angiographically confirmed coronary aneurysm.
- Trial name
- CAAR (NCT02563626)
- Where
- Spain
- Volunteers
- 1,565 people
- Sponsor
- St Carlos Hospital, Madrid, Spain
Acute Coronary Syndrome
AngioSeal Versus Radial Approach in Acute Coronary Syndrome
Among non-ST-segment elevation acute coronary syndrome patients submitted to early invasive strategy and randomized for the transfemoral or transradial approach, the AngioSeal vascular closure device would decrease the prevalence…
- Trial name
- ARISE (NCT01653587)
- Testing
- Percutaneous coronary intervention
- Where
- Brazil
- Volunteers
- 240 people
- Sponsor
- Irmandade Santa Casa Misericórdia Marília
Myocardial Infarction (MI), Radiation Toxicity
A MAajor RAdiation-based PCI Study in STEMI and NSTEMI
In France and Italy, approximately 240,000 percutaneous coronary angioplasties (PCI) are performed annually, with an increasing number of complex procedures, including those involving the left coronary common trunk, a…
- Conditions
- Myocardial Infarction (MI), Radiation Toxicity, Coronary Stenosis, Coronary Thrombosis
- Trial name
- MARAA (NCT06565793)
- Testing
- Non Complex PCI, Complex PCI
- Where
- France
- Volunteers
- 15,630 people
- Sponsor
- Centre Cardiologique du Nord
Acute Ischemic Stroke, Thrombocytopenia
Antiplatelet Therapy for AIS Patients With Thrombocytopenia
The goal of this clinical trial is to test the safety and effectiveness of antiplatelet therapy in acute ischemic stroke (AIS) patients with thrombocytopenia.
- Trial name
- PERSIST (NCT06053021)
- Testing
- aspirin, clopidogrel, cilostazol, and dipyridamole
- Where
- China
- Volunteers
- 1,200 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Peripheral Artery Occlusive Disease, Acute Coronary Syndrome
The Prevalence Survey of ALDH Gene Family in Patients With Peripheral Arterial Occlusive Disease or Acute Coronary Syndrome
Aldehyde dehydrogenase 2 (ALDH2) is an important enzyme protecting human from the accumulation of aldehyde, the main metabolites of alcohol.
- Trial name
- NCT05078814
- Testing
- Observational research
- Where
- Taiwan
- Volunteers
- 600 people
- Sponsor
- Chimei Medical Center
Coronary Artery Disease (CAD)
Endothelial Progenitor Cells and Nitric Oxide in Cardiac Rehabilitation Program Participants
This study will measure blood levels of endothelial progenitor cells (EPCs) and nitric oxide (NO) in patients with coronary artery disease (CAD) who are participating in a 3-month cardiac rehabilitation program at Suburban…
- Trial name
- NCT00308633
- Where
- 2 sites in United States
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- National Heart, Lung, and Blood Institute (NHLBI)
Unstable Angina, Myocardial Infarction
Comparison of Angiomax Versus Heparin in Acute Coronary Syndromes (ACS)
The purpose of this study is to show that, when compared with heparin (enoxaparin or unfractionated heparin) and routine GPIIb/IIIa inhibition (either started upfront or at the time of percutaneous coronary intervention [PCI]…
- Conditions
- Unstable Angina, Myocardial Infarction, Acute Disease
- Trial name
- NCT00093158
- Testing
- Angiomax (bivalirudin) anticoagulant
- Where
- United States
- Volunteers
- 13,800 people
- Sponsor
- The Medicines Company