Clinical trials: Ischemic Brain
Atrial Fibrillation, Stroke, Ischemic
Use of Oral Anticoagulants and Symptoms in Patients With Atrial Fibrillation in Örebro County
Atrial fibrillation (AF) is the most common sustained arrhythmia and the number of patients with AF is expected to increase substantially in the coming decades.
- Trial name
- NCT04233515
- Testing
- Oral anticoagulant
- Where
- Sweden
- Volunteers
- 11,964 people
- Sponsor
- Region Örebro County
Acute Ischemic Stroke
Intravenous Tirofiban After Delayed Thrombolysis in Stroke
A multicenter, double-blind, double-dummy, randomized trial evaluating the efficacy and safety of intravenous tirofiban in acute ischemic stroke (AIS) patients without large/medium vessel occlusion, who presented 4.5-24 hours…
- Trial name
- PEARL-TIRO (NCT07111806)
- Testing
- Tirofiban
- Where
- China
- Volunteers
- 852 people
- Sponsor
- Sun Yat-Sen Memorial Hospital of Sun Yat-Sen University
Hypoxic-Ischemic Encephalopathy
Neurological Outcome After Erythropoietin Treatment for Neonatal Encephalopathy
Perinatal asphyxia-induced brain injury is one of the most common causes of morbidity and mortality in term and preterm neonates, accounting for 23% of neonatal deaths globally.
- Trial name
- NCT00808704
- Testing
- recombinant human erythropoietin
- Where
- China
- Volunteers
- 167 people
- Sponsor
- Zhengzhou University
Spinal Cord Injury, Stroke (CVA) or Transient Ischemic Attack
Understanding and Enhancing Human Health and Movement
By doing this study, investigators hope to learn how electrical stimulation can improve human movement, biomechanics, and function and to gather information on the safety and effectiveness of an implanted electrical stimulation…
- Conditions
- Spinal Cord Injury, Stroke (CVA) or Transient Ischemic Attack, Multiple Sclerosis
- Trial name
- NCT07738978
- Testing
- Neural Prosthesis
- Where
- United States
- Volunteers
- 75 people
- Sponsor
- Louis Stokes VA Medical Center
Coronary Artery Disease, Cerebrovascular Disease
RESTORE-IT-Study of Rifalazil in Chlamydia Pneumoniae Seropositive Patients With a History of Atherosclerotic Disease
The objective of this study is to evaluate an antibiotic therapy called Rifalazil to determine its effect on hardening of the carotid arteries.
- Conditions
- Coronary Artery Disease, Cerebrovascular Disease, Peripheral Vascular Disease
- Trial name
- NCT00385385
- Testing
- Rifalazil
- Where
- 6 sites in United States, Canada
- Volunteers
- 72 people
- Sponsor
- ActivBiotics
Hypoxic Preconditioning, Carotid Artery Stenosis
Hypoxic Preconditioning on Patients
The purpose of this study is to study the effects of intermittent whole-body hypoxic preconditioning on patients with carotid artery stenosis.
- Conditions
- Hypoxic Preconditioning, Carotid Artery Stenosis, Ischemic Cerebrovascular Disease
- Trial name
- NCT02966418
- Testing
- Mild Hypoxia Preconditioning
- Where
- China
- Volunteers
- 50 people
- Sponsor
- Hua Yan
Subarachnoid Hemorrhage, Hypoxia Ischemia, Cerebral
Combined Intracerebral and Jugular Bulb Microdialysis
The first aim of this study is to investigate the frequency and severity of a specific pathological metabolic pattern, mitochondrial dysfunction, of the brain in comatose patients under neurocritical care.
- Conditions
- Subarachnoid Hemorrhage, Hypoxia Ischemia, Cerebral, TBI, Meningitis
- Trial name
- NCT03314779
- Where
- Denmark
- Volunteers
- 12 people
- Sponsor
- Odense University Hospital
Acute Ischemic Stroke
LEG-UP Feasibility Study: Elevated Leg Positioning For Acute Moderate Ischemic Stroke
Augmentation of penumbral perfusion through nonpharmacological hemodynamic interventions such as patient positioning may offer a pragmatic approach to improve outcomes in acute ischemic stroke (AIS).
- Trial name
- LEG-UP (NCT07483580)
- Testing
- Elevated Leg Positioning
- Where
- Philippines
- Volunteers
- 50 people
- Sponsor
- Bonifacio C. Pedreogsa II
Early Ambulation, Standard of Care
The Investigation of the Impact of Early Mobilization on the Outcome in Patients With Aneurysmal Subarachnoid Hemorrhage.
The goal of the randomized clinical trial is to examine the effect of early mobilization on primary and secondary outcomes in patients with subarachnoid hemorrhage caused by aneurysm rupture.
- Conditions
- Early Ambulation, Standard of Care, Subarachnoid Hemorrhage, Aneurysmal
- Trial name
- NCT06436508
- Testing
- Early mobilization protocol, Standard care
- Where
- 3 sites in Hungary
- Volunteers
- 50 people
- Sponsor
- University of Pecs
Ischemic Cerebrovascular Accident
Clopidogrel for Acute Ischaemia of Recent Onset
Evaluate the role of loading Clopidogrel in acute ischemic stroke in improving neurological outcome of stroke in cases patients will be non-eligible for, or declined, treatment with or intravenous thrombolysis with rTPA, rTPA is…
- Trial name
- CAIRO (NCT02776540)
- Testing
- Clopidogrel, Aspirin
- Where
- Egypt
- Volunteers
- 188 people
- Sponsor
- Ain Shams University
Infection, Acute Coronary Syndrome
Association Between Levels of D-Dimer, Fibrinogen and PAI-1 in Elderly Patients With Infection and Occurrence of Cardio- and Cerebro-vascular Disease After Discharge
The association between the levels of d-dimer, fibrinogen and PAI-1 in plasma of elderly patients admitted to internal medicine departments because of infection and the occurrence of cardio- and cerebro-vascular disease after…
- Conditions
- Infection, Acute Coronary Syndrome, Cerebrovascular Disease
- Trial name
- NCT00512603
- Volunteers
- 52 people
- Sponsor
- Wolfson Medical Center
Cerebral Infarction, Disease
A Multi-center Prospective Study of Branch Atheromatous Disease in China
Branch atheromatous disease (BAD), is regarded as one of the important etiologies for acute isolated subcortical infarction, especially in Asian population.
- Conditions
- Cerebral Infarction, Disease, Magnetic Resonance Imaging
- Trial name
- NCT04973774
- Where
- China
- Volunteers
- 600 people
- Sponsor
- Peking Union Medical College Hospital
Acute Ischemic Stroke
A Study to Evaluate Safety and PK of Multiple Doses of LT3001 Drug Product and Drug-drug Interaction in Healthy Subjects
This Phase 1 study is planned to establish the clinical safety and pharmacokinetics profile of multiple dose of LT3001 drug product and to investigate drug interactions of LT3001 with potential concomitant medications in healthy…
- Trial name
- NCT04809818
- Testing
- LT3001 drug product, Aspirin, Clopidogrel
- Where
- United States
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Lumosa Therapeutics Co., Ltd.
Ischemic Stroke
Prevalence of Cerebral Large Vessel Occlusion Among Acute Ischemic Stroke Patients in Assiut University Hospitals
Prevalence of Large Vessel Occlusion among acute ischemic stroke patients in Assiut University hospitals 1. Study Objectives Primary Objective: To determine the prevalence of LVO among acute ischemic stroke (AIS) patients…
- Trial name
- NCT07326410
- Volunteers
- 300 people
- Sponsor
- Assiut University
Stroke, Cardiovascular
Effects of the Insole on Balance Capacity in Chronic Stroke
Poor balance capacity is one of clinical symptoms of stroke patient. The reason of loss balance capacity is motor impairment, as well as a diminished capacity to voluntarily shift body weight or to with stand external…
- Trial name
- NCT03194282
- Testing
- insole
- Where
- Taiwan
- Volunteers
- 32 people
- Sponsor
- Taipei Medical University WanFang Hospital
Stroke, Ischemic, Stroke/Brain Attack
Manually Controlled Infusion Vs Target Controlled Infusion for StrokeThrombectomy
The goal of this randomized controlled trial is to compare manual general anesthesia induction to general anesthesia induction guided by target controlled infusion system in cerebral ischemic stroke The main questions it aims to…
- Conditions
- Stroke, Ischemic, Stroke/Brain Attack, Anesthesia, Hemodynamic Instability
- Trial name
- HASTE (NCT05570682)
- Testing
- TCI, Manual induction
- Where
- Italy
- Sponsor
- University of Padova
Cardiovascular Diseases, Heart Diseases
Postmenopausal Progestins, MI and Stroke
To evaluate the cardiovascular effects of postmenopausal hormone replacement therapy and the suspected beneficial effects on myocardial infarction and stroke.
- Conditions
- Cardiovascular Diseases, Heart Diseases, Coronary Disease, Cerebrovascular Accident
- Trial name
- NCT00005220
- Sponsor
- University of Washington
Acute Ischemic Stroke
The Vesalio NeVa Stent Retriever Study for Treatment of Large Vessel Occlusion Strokes: CLEAR Study
A prospective, open label, single-arm 90-day study designed to assess the safety, performance and efficacy of thrombus removal in subjects presenting with acute ischemic stroke with the NeVa stent retrievers.
- Trial name
- NCT04514562
- Testing
- NeVa Stent Retrievers
- Where
- 7 sites in United States
- Volunteers
- 120 people
- Sponsor
- Vesalio
Brain Ischemia
A Feasibility Study for Randomization of Code Stroke Imaging Strategies
The purpose of this study is to test feasibility of a comparative effectiveness framework for acute stroke imaging using prospective electronic health data.
- Trial name
- CSI (NCT06270927)
- Testing
- MRI, CT
- Where
- United States
- Volunteers
- 600 people, healthy volunteers welcome
- Sponsor
- University of Texas at Austin
Age-related Macular Degeneration, Coronary Artery Disease
Ranibizumab and the Risk of Arterial Thromboembolic Events
The investigators assume that ranibizumab might be dangerous in patients with history of coronary artery disease or cerebrovascular events.
- Conditions
- Age-related Macular Degeneration, Coronary Artery Disease, Cerebrovascular Disorders
- Trial name
- RATE (NCT01319188)
- Testing
- 0.5 mg of ranibizumab, 0.5 mg of ranibizumab + photodynamic therapy
- Where
- 2 sites in Netherlands, Russia
- Volunteers
- 380 people, healthy volunteers welcome
- Sponsor
- Ural State Medical University
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