Clinical trials: Ischemic Conditioning
Refractory Angina Pectoris
Effect of Daily Remote Ischemic Conditioning on the Life Quality of Refractory Angina Pectoris Patients
The purpose is to test whether daily ischemic conditioning of the arms over 30 days could reduce the frequency and severity of angina pectoris and improve the life quality of refractory angina pectoris patients.
- Trial name
- D-RIC-RAP (NCT02499250)
- Testing
- remote ischemic conditioning (TDFT-12-A2), Optimal medical treatment
- Where
- China
- Volunteers
- 30 people
- Sponsor
- Navy General Hospital, Beijing
ST-elevation Myocardial Infarction
Effect of Conditioning on Myocardial Damage in STEMI
The LIPSIA-Conditioning trial is an investigater initiated, randomized, single-center study that will assess the effect of different intrahospital conditioning protocols on myocardial damage assessed by MRI in patients with acute…
- Trial name
- LIPSIA-COND (NCT02158468)
- Testing
- Combined intrahospital pre- and postconditioning, Postconditioning
- Where
- Germany
- Volunteers
- 600 people
- Sponsor
- University of Leipzig
Myocardial Infarction
Post-conditioning to Reduce Infarct Size
When angioplasty (PTCA) and stenting of the blood vessels of the heart is the treatment for a Heart Attack, there is damage to the heart muscle that is caused by the sudden opening of the blood vessels.
- Trial name
- NCT00755469
- Testing
- Post-conditioning
- Where
- United States
- Volunteers
- 43 people
- Sponsor
- Minneapolis Heart Institute Foundation
Acute Stroke
Remote Ischemic Conditioning Paired With Endovascular Treatment for Acute Ischemic Stroke (REVISE-1)
Currently, early reperfusion is considered as the most effective therapy for the treatment of acute ischemic stroke (AIS). Over the past 20 years, intravenous tissue plasminogen activator (IV tPA) has been demonstrated to be the…
- Trial name
- NCT03210051
- Testing
- Remote ischemic conditioning, Endovascular treatment
- Where
- China
- Volunteers
- 20 people
- Sponsor
- Capital Medical University
Ischemic Stroke
Remote Ischemic Conditioning for Acute Moderate Posterior Ischemic Stroke
A substantial body of basic and clinical research has demonstrated the protective effects of remote ischemic conditioning (RIC) in ischemic stroke.
- Trial name
- RICAMIS2 (NCT06931535)
- Testing
- remote ischemic conditioning
- Where
- China
- Volunteers
- 1,600 people
- Sponsor
- General Hospital of Shenyang Military Region
Chronic Cerebral Ischemia, Intracranial Atherosclerosis
Optimized Remote Ischemic Conditioning (RIC) Treatment for Patients With Chronic Cerebral Ischemia
This prospective, randomized, single-center clinical trial is designed to figure out the most optimal algorithm of remote ischemic conditioning on patients with chronic cerebral ischemia.
- Trial name
- NCT03105141
- Testing
- Remote ischemic conditioning
- Where
- 2 sites in China
- Volunteers
- 600 people
- Sponsor
- Capital Medical University
Intracranial Atherosclerosis
Pilot Study of Pre-Ischemic Conditioning for Intracranial Atherosclerosis
The purpose of this study is to determine the effects of the Doctormate device, a specialized blood pressure cuff used to perform remote limb ischemic conditioning, on cerebral blood flow in subjects with intracranial…
- Trial name
- PICASSO (NCT03208166)
- Testing
- Doctormate, Usual Care
- Where
- United States
- Volunteers
- 2 people
- Sponsor
- Medical University of South Carolina
High Altitude Polycythemia
Remote Ischemic Conditioning for High Altitude Polycythemia in High-Altitude Immigrant Populations
This study is a multicenter, prospective, randomized, open-label, parallel-controlled clinical trial. The participants are adult patients with high-altitude polycythemia who have been long-term residents (for >6 months) in…
- Trial name
- NCT07562464
- Testing
- RIC
- Volunteers
- 222 people
- Sponsor
- Capital Medical University
STEMI, Myocardial Reperfusion Injury
Effect of Remote Ischaemic Conditioning on Clinical Outcomes in STEMI Patients Undergoing PPCI (CONDI2/ERIC-PPCI)
The purpose of this study is to determine whether remote ischemic conditioning can reduce cardiac death and hospitalization for heart failure at 12 months in patients presenting with a ST-elevation myocardial infarction and…
- Trial name
- NCT02342522
- Testing
- Remote ischemic conditioning, Control
- Where
- 35 sites in Denmark, Serbia and 2 more
- Volunteers
- 5,413 people
- Sponsor
- University College, London
Pre-Eclampsia; Mild, Gestational Hypertension
Effect of RIC on BP and Inflammatory Response in Women With Pre-eclampsia
The aim of this pilot cohort study is to investigate whether treatment with remote ischemic conditioning (RIC) has a beneficial effect on blood pressure as well as the immune system in pregnant women with newly diagnosed…
- Trial name
- NCT03323762
- Testing
- Remote Ischaemic Conditioning (RIC)
- Where
- 3 sites in Denmark
- Volunteers
- 10 people
- Sponsor
- University of Aarhus
Esophageal Anastomotic Leak, Tissue Pressure of Oxygen
Ischemic Conditioning of the Gastric Conduit in Esophageal Cancer.
This study is a randomized clinical trial to clarify if preoperative embolization of gastric arteries can reduce the incidence of oesophagogastric leakage after an esophagectomy for esophageal cancer comparing an experimental…
- Trial name
- NCT04268654
- Testing
- Preoperative Arterial Embolization
- Where
- Spain
- Volunteers
- 40 people
- Sponsor
- Fundación para la Investigación del Hospital Clínico de Valencia
Leg Ulcer, Varicose Ulcer
Remote Ischemic Conditioning for Treatment of Chronic Wounds
The goals of this series of studies is to test the effect of RIC on chronic leg ulcers (Diabetic ulcers and venous ulcers) - and to improve the understanding of its biological mechanism.
- Trial name
- NCT02873728
- Testing
- Remote Ischemic Conditioning, Control
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Soroka University Medical Center
Stroke, Vascular Diseases
Passive Limb Movement Study
Stroke survivors have compromised vascular function which may contribute to secondary stroke risk, cardiovascular disease, and may limit their exercise tolerance.
- Conditions
- Stroke, Vascular Diseases, Ischemic
- Trial name
- PLM (NCT05935670)
- Testing
- Ischemic Conditioning
- Where
- United States
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Medical College of Wisconsin
Diabetes Mellitus, Coronary Artery Bypass
Remote Ischemic Preconditioning in Type 2 Diabetic Patients Undergoing CABG
This randomized, double-blind, prospective clinical trial aims to investigate the effect of remote ischemic preconditioning (RIPC) on myocardial protection in patients with type 2 diabetes mellitus undergoing elective coronary…
- Conditions
- Diabetes Mellitus, Coronary Artery Bypass, Remote Ischaemic Conditioning
- Trial name
- NCT06977230
- Testing
- Remote Ischemic Preconditioning
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Muğla Sıtkı Koçman University
ST Elevation Myocardial Infarction
Remote Ischemic Conditioning With Local Ischemic Postconditioning in High-Risk ST-elevation Myocardial Infarction
The RIP-HIGH trial is a two-arm randomized controlled trial aiming to compare the impact of combined remote ischemic conditioning (RIP) and local ischemic postconditioning (PostC) vs.
- Trial name
- RIP-HIGH (NCT04844931)
- Testing
- RIC + PostC + Standard PCI, Standard PCI
- Where
- 11 sites in Austria, Germany
- Volunteers
- 250 people
- Sponsor
- Helios Health Institute GmbH
COVID, Corona Virus Infection
RIC as an Adjunct Therapy for Severe COVID-19 Disease: a Prospective Randomized Pilot Study
This research aims to assess the use of an experimental and non-invasive procedure, Remote Ischemic Conditioning (RIC), as an adjunct therapy in attenuating severe COVID-19 disease.
- Conditions
- COVID, Corona Virus Infection, Acute Lung Injury, Ischemia Limb
- Trial name
- NCT04659460
- Testing
- Remote Ischemic Conditioning
- Volunteers
- 30 people
- Sponsor
- Unity Health Toronto
Moyamoya Disease, Moyamoya Syndrome
Evaluating Antiplatelet and Physical Therapy for Slowing Progression in Mild Moyamoya Disease.
Moyamoya disease (MMD) is a chronic occlusive cerebrovascular disease characterized by progressive stenosis or occlusion at the terminal portion of the internal carotid artery, with formation of an abnormal vascular network at…
- Conditions
- Moyamoya Disease, Moyamoya Syndrome, Aspirin, Remote Ischemic Conditioning
- Trial name
- MOUNT-EASE (NCT07762547)
- Testing
- aspirin treatment, Remote Ischemic Conditioning
- Where
- China
- Volunteers
- 724 people
- Sponsor
- Beijing Tiantan Hospital
Ischemic Preconditioning
Conditioning Based Intervention Strategies
The overall objective of this study is to uncover and utilize the mechanisms behind the activation of endogenous organ protection by remote ischemic conditioning (RIC), high intensity traditional resistance training (TRT) and low…
- Trial name
- ConBIS (NCT03380663)
- Testing
- Remote Ischemic Conditioning (RIC)
- Where
- Denmark
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- University of Aarhus
ST-elevation Myocardial Infarction
Cost-effectiveness of Remote Ischemic Conditioning as an Adjunct to Primary Percutaneous Coronary Intervention
The aim of this study is to investigate the cost-effectiveness of remote ischemic conditioning as an adjunct to primary percutaneous coronary intervention from the perspective of a Danish healthcare system.
- Trial name
- NCT02431338
- Testing
- Remote ischemic conditioning
- Where
- Denmark
- Volunteers
- 333 people
- Sponsor
- University of Aarhus
Ischemic Stroke, Acute, Myocardial Injury
Safety and Efficacy of Remote Ischemic Conditioning in Patients With Acute Myocardial Injury Following Acute Ischemic Stroke
Introduction: The management of acute myocardial injury following acute ischemic stroke (AMI-AIS), a frequent complication that severely worsens prognosis, is challenging.
- Trial name
- NCT07531394
- Testing
- Remote Ischemic Conditioning
- Volunteers
- 580 people
- Sponsor
- Capital Medical University