Clinical trials: Ischemic Disease
Acute Ischemic Stroke
Enoxaparin and/or Minocycline in Acute Stroke
The purpose of this study is to investigate whether enoxaparin, minocycline, or both medications in combination may help in recovery from acute stroke.
- Trial name
- NCT00836355
- Testing
- Enoxaparin, Minocycline
- Where
- 2 sites in United States
- Volunteers
- 6 people
- Sponsor
- NYU Langone Health
Tako-Tsubo Cardiomyopathy, Stress-induced Cardiomyopathy
The TAKO-TSUBO And Cancer Registry
Prospective, multicenter, observational registry collecting data from subjects with Tako-Tsubo (stress-induced) cardiomyopathy (TTC).
- Conditions
- Tako-Tsubo Cardiomyopathy, Stress-induced Cardiomyopathy, Acute Coronary Syndrome
- Trial name
- TTAC (NCT01944826)
- Testing
- Registry of patients with Tako-Tsubo cardiomyopathy
- Where
- Germany
- Volunteers
- 800 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Acute Myocardial Infarction, Acute Coronary Syndrome
Use of High Sensitivity Cardiac Troponin In Ruling Out Emergency Patients With Acute Myocardial Injury and Infarction
Examine the analytical and clinical performance of Atellica IM TnIH assay for the diagnosis and rule out of acute myocardial injury and myocardial infarction in patients presenting to the emergency department in whom serial cTnI…
- Trial name
- SAFETY (NCT04280926)
- Testing
- Cardiac Troponin Testing
- Where
- United States
- Volunteers
- 1,000 people
- Sponsor
- Fred Apple
Cardiotoxicity
Effect of Remote Ischaemic Conditioning in Oncology Patients
Cancer survival has improved steadily due to earlier detection and treatment. Despite the established efficacy of anthracycline chemotherapy, its damaging effects on the heart (cardiotoxicity) limits treatment and confers acute…
- Trial name
- ERIC-ONC (NCT02471885)
- Testing
- Remote Ischaemic Conditioning
- Where
- United Kingdom
- Volunteers
- 128 people
- Sponsor
- University College, London
Coronary Artery Disease
A Prospective Trial of Ayurveda for Coronary Artery Disease
Can Ayurvedic therapy improve markers of cardiovascular health and cardiovascular risk factors in patients with coronary artery disease.
- Trial name
- NCT02228343
- Testing
- Ayurveda
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- University of New Mexico
Diabetic Macular Edema, Diabetic Retinopathy
Increase in Capillary Plexus Density Level Following the Use of Ozurdex for the Treatment of DME
The objective of this study is to test the hypothesis that following the use of intravitreal dexamethasone implant for the treatment of DME, there will be an observable increase in the capillary density plexus as denoted by the…
- Conditions
- Diabetic Macular Edema, Diabetic Retinopathy, Retinal Ischemia
- Trial name
- ICOD (NCT04038125)
- Testing
- Ozurdex Drug Implant Product
- Where
- 2 sites in United States
- Volunteers
- 20 people
- Sponsor
- Retina Macula Specialists of Miami, LLC
Stroke
The Stroke Warning Information and Faster Treatment Study (SWIFT)
The purposes of this study are to determine the effectiveness of an interactive stroke educational program compared to standard educational materials and usual care, to increase stroke knowledge, and to improve emergency room…
- Trial name
- NCT00415389
- Testing
- interactive educational program, usual medical care
- Where
- United States
- Volunteers
- 1,635 people
- Sponsor
- Columbia University
Coronary Artery Disease
Impact of Three Body Positioning Strategies in the Drainage Fluids After Coronary Artery Bypass Surgery
To investigate different strategies of body positioning associated to early corporal mobilization and verify the impact int the time and quantification of thoracic and mediastinal drainage, pulmonary complications and time of…
- Trial name
- positioning (NCT02525289)
- Testing
- Bed Rotation Group, Orthostatic Group
- Volunteers
- 101 people
- Sponsor
- University of Sao Paulo General Hospital
Stroke, Acute, Ischemic Stroke
Neurodevelopmental Therapy-Bobath Approach in The Early Term of Stroke; Safe and Effective
Early term rehabilitation initiated after stroke should be based on motor learning principles and neural plasticity. To achieve motor learning and neural plasticity, exercises consisting of intense and repetitive training should…
- Trial name
- NCT03602326
- Testing
- Neurodevelopmental Therapy-Bobath group, Standart Rehabilitation Group (SR group)
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Gokhan Yazici
Coronary Disease
Prognostic Implications of Physiologic Investigation After Revascularization With Stent
Percutaneous coronary intervention (PCI) is a standard treatment strategy for coronary artery disease (CAD). With the presence of myocardial ischemia, PCI reduces the risks of death, myocardial infarction (MI) and…
- Trial name
- POST-PCI FLOW (NCT04684043)
- Testing
- Percutaneous coronary intervention
- Where
- South Korea
- Volunteers
- 5,100 people
- Sponsor
- Bon-Kwon Koo
Ischemic Stroke
Ticagrelor Versus Clopidogrel in Large Vessel Ischemic Stroke
Along with the current clinical trial, the efficacy and safety of 180 mg loading dose of ticagrelor administered within 24 hours of first-ever large-vessel ischemic stroke compared to 300 mg clopidogrel were assessed through…
- Trial name
- NCT06120725
- Testing
- Ticagrelor 90 MG, Clopidogrel
- Where
- Egypt
- Volunteers
- 580 people
- Sponsor
- Kafrelsheikh University
Coronary Artery Disease, Angina Pectoris
Appropriateness of Angioplasty in Patients With Chronic Coronary Syndromes
Percutaneous coronary intervention (PCI) has dramatically changed the treatment of obstructive coronary artery disease patients.
- Trial name
- RIGHT-PCI (NCT06545448)
- Testing
- Percutaneous Coronary Intervention (PCI)
- Where
- Brazil
- Volunteers
- 1,875 people
- Sponsor
- University of Sao Paulo General Hospital
Peripheral Vascular Diseases
Phase I/II Trial of Endometrial Regenerative Cells (ERC) in Patients With Critical Limb Ischemia
This is a 15 patient clinical trial assessing the safety and feasibility of using Endometrial Regenerative Cells (ERC) in patients with critical limb ischemia (CLI) that are not eligible for surgical or catheter-based…
- Trial name
- NCT01558908
- Testing
- Administration of ERC
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Medistem Inc.
Arthritis, Asthma
Mobility Assessment in Multi-morbidity
Multimorbidity (the presence of two or more coexisting long-term conditions) is a significant challenge facing the NHS, especially given UK's ageing population and the association with high levels of illness burden and healthcare…
- Conditions
- Arthritis, Asthma, Atrial Fibrillation, Bronchiectasis
- Trial name
- Multi-mobility (NCT06473168)
- Volunteers
- 55 people
- Sponsor
- Northumbria University
Coronary Artery Disease, PCI
Age-Dependent Impact of the SYNTAX-score on Mortality
The SYNTAX-score has been proposed as a tool for risk stratification and guiding revascularization therapy in patients with complex coronary artery disease.
- Trial name
- NCT03479840
- Testing
- PCI
- Where
- Germany
- Volunteers
- 1,331 people
- Sponsor
- LMU Klinikum
Cardiogenic Shock
Awake Axillary Impella 5.5 Placement - A Feasibility Trial
The Abiomed Impella 5.5 is a surgically placed temporary mechanical support device used in patients in cardiogenic shock. The investigators propose using regional anesthesia (3 separate peripheral nerve blocks) to facilitate…
- Trial name
- NCT05782491
- Testing
- Interscalene Block, PECS II Block, Superficial Cervical Plexus Block
- Where
- 2 sites in United States
- Sponsor
- University of Pennsylvania
Hypoxic-Ischemic Encephalopathy
RIC in HIE: A Safety and Feasibility Trial
Remote Ischemic Conditioning has never been studied in neonates with HIE. However, RIC has been studied in animal models of perinatal asphyxia and has shown encouraging results.
- Trial name
- NCT05379218
- Testing
- Remote Ischemic Conditioning
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- The Hospital for Sick Children
Acute Coronary Syndrome, Myocardial Infarction
Efficacy of Preoperative Electrocardiography
A preoperative electrocardiogram (ECG) is nearly routinely performed by anesthesiologists in elderly non-cardiac surgery patients as part of pre-anesthesia evaluation.
- Conditions
- Acute Coronary Syndrome, Myocardial Infarction, Cardiac Arrest
- Trial name
- NCT00928460
- Testing
- Removal of preoperative electrocardiogram
- Where
- Netherlands
- Sponsor
- UMC Utrecht
Coronary Microvascular Disease
Qishenyiqi Dripping Pill for Coronary Microvascular Disease
To investigate the efficacy and safety of Qishenyiqi in patients with microvascular angina pectoris. Long-term follow-up of 1 year will be performed to evaluate the effect of Qishenyiqi on coronary flow reserve and adverse…
- Trial name
- CMVD (NCT06699420)
- Testing
- Qishenyiqi dripping pills 1 bag, three times a day
- Where
- 3 sites in China
- Volunteers
- 162 people
- Sponsor
- Qilu Hospital of Shandong University
Acute Myocardial Infarction With ST Segment Elevation
3 Nehb Precordial Leads Anterior, Dorsalis and Inferior Allow Accurate Diagnostics of Different Heart Conditions
The method of ECG recording with the use of three bipolar leads A (anterior), D dorsalis) and J (or I - inferior) was introduced in 1938 by German electrophysiologist W. Nehb.
- Trial name
- Nehb-STEMI (NCT00623896)
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Assaf-Harofeh Medical Center
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