Clinical trials: Ischemic Disease
Acute Heart Failure, Acute Coronary Syndrome
Heart Failure-USB: Prediction and Progression
This retrospective cohort study is to identify triggers of heart failure (HF) development and drivers of HF progression as well as the underlying cardiac disease (phenotype) to identify patients at risk and predict the clinical…
- Trial name
- HF-USB (NCT04000061)
- Testing
- medical chart review, data generated by direct IT export
- Where
- Switzerland
- Volunteers
- 6,000 people
- Sponsor
- University Hospital, Basel, Switzerland
Coronary Artery Disease
Mainz Registry of Flow-mediated Constriction
The goal of the flow-mediated constriction/ FMC-registry is to investigate whether the measurement of endothelial function using flow-mediated dilation and flow-mediated constriction provides on the presence of coronary…
- Trial name
- NCT01787370
- Where
- Germany
- Volunteers
- 750 people
- Sponsor
- Johannes Gutenberg University Mainz
Ischemic Stroke, Atherosclerosis of Artery
Efficacy of Probucol Combined with Statins Treatment for Ischemic Stroke
The goal of this clinical trial is to evaluate whether the combination of Probucol with statin therapy can reduce the risk of vascular events and improve atherosclerosis outcomes in adults with ischemic stroke and confirmed…
- Conditions
- Ischemic Stroke, Atherosclerosis of Artery, Lipid Disorder, Statin
- Trial name
- EPCIS (NCT06604117)
- Testing
- Statin, Probucol
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Xuanwu Hospital, Beijing
Ischemic Stroke
Prospective Cohort With Incident Stroke
The primary aim of the study is to derive and validate risk scores for vascular endpoints (recurrent stroke, myocardial infarction, and other complications of stroke) and for death following an incident stroke.
- Trial name
- PROSCIS (NCT01364168)
- Where
- 2 sites in Germany
- Volunteers
- 850 people
- Sponsor
- Ludwig-Maximilians - University of Munich
OSA, Heart Failure
Impact of Early Diagnosis and Treatment of OSA on Hospital Readmission in Hospitalized Cardiac Patients
The purpose of this study is to determine whether early diagnosis of obstructive sleep apnea and initiation of and adherence to CPAP therapy in hospitalized cardiac patients would impact 30-day hospital readmission rates.
- Conditions
- OSA, Heart Failure, Myocardial Infarction, Arrhythmia, Cardiac
- Trial name
- CV Readmit (NCT03647891)
- Testing
- Continuous Positive Airway Pressure
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Kaiser Permanente
Chronic Limb-Threatening Ischemia
Chronic Limb-Threatening Ischemia Treated With Intravascular Lithotripsy Observational Study
CALCIO is a multicentre, prospective, observational cohort study that will collect real world data on the use of intravascular Lithotripsy (IVL) with the Shockwave IVL system to disrupt calcified femoropopliteal and crural…
- Trial name
- CALCIO (NCT06149650)
- Testing
- Shockwave Medical IVL System
- Where
- 39 sites in Austria, Canada and 6 more
- Volunteers
- 400 people
- Sponsor
- Cardiovascular and Interventional Radiological Society of Europe
Stroke, Transient Ischemic Attack
SLEep APnea Screening Using Mobile Ambulatory Recorders After TIA/Stroke
Obstructive sleep apnea (OSA) is common after stroke/TIA and, left untreated, is associated with recurrent vascular events, poor functional outcomes, and long-term mortality.
- Conditions
- Stroke, Transient Ischemic Attack, Obstructive Sleep Apnea
- Trial name
- SLEAP SMART (NCT02454023)
- Testing
- Portable sleep monitor (ApneaLink Air), In-laboratory polysomnography
- Where
- Canada
- Volunteers
- 250 people
- Sponsor
- Sunnybrook Health Sciences Centre
Cardiogenic Shock Post Myocardial Infarction
Rapid Microaxial Flow Pump Support and Escalation in Patients With Myocardial Infarction Associated Cardiogenic Shock and Persistent Need of Hemodynamic Support
The aim of this trial is to evaluate whether a structured and time-optimized escalation strategy from a transfemoral microaxial flow-pump (Impella CP™) to the Impella 5.5™ microaxial flow-pump is associated with improved clinical…
- Trial name
- RISE (NCT07655479)
- Testing
- Escalation to more capable microaxial flow-pump (Impella 5.5)
- Where
- 3 sites in Germany
- Volunteers
- 115 people
- Sponsor
- University Hospital of Cologne
Cardiovascular Risk Factor, Insulin Resistance
Chronic Cardiovascular Risk Outpatient Management in South Asians Using Digital Health Technology
This platform will enable investigation the cardiovascular risk reduction and the increase in participant engagement in their heart-healthy goals, through the use of virtual care/telemedicine with a digital platform that connects…
- Conditions
- Cardiovascular Risk Factor, Insulin Resistance, PreDiabetes, Diabetes
- Trial name
- HealthPals (NCT03167996)
- Testing
- Use of HealthPals (Telemedicine supported by digital health platform)
- Where
- United States
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Stanford University
Coronary Arteriosclerosis, Heart Failure, Congestive
Evaluation of Myocardial Viability by Means of Low-dose Dobutamine Gated SPECT (the DOGS Study)
Viability assessment remains a clinical challenge in patient with coronary artery disease and left ventricular dysfunction. Several imaging modalities are available for evaluating myocardial viability, based either on perfusion…
- Conditions
- Coronary Arteriosclerosis, Heart Failure, Congestive, Myocardial Infarction, Myocardial Ischemia
- Trial name
- NCT00213746
- Where
- 8 sites in Belgium, France
- Volunteers
- 75 people
- Sponsor
- University Hospital, Rouen
Respiratory Insufficiency, Pulmonary Disease, Chronic Obstructive
The Effect of Aromatherapy Massage on Pain, Anxiety and Comfort
Patients in the intensive care unit (ICU) experience physical and psychological discomfort, including pain. Anxiety is a condition frequently encountered in the ICU.
- Conditions
- Respiratory Insufficiency, Pulmonary Disease, Chronic Obstructive, Diabetes Mellitus, Type 2, High Blood Pressure
- Trial name
- NCT06295874
- Testing
- Effect of aromatherapy massage on vital signs, pain, anxiety and comfort level
- Where
- Turkey (Türkiye)
- Volunteers
- 61 people, healthy volunteers welcome
- Sponsor
- Nilgün Erdoğan
Stroke
Efficacy and Safety of MRI-based Thrombolysis in Wake-up Stroke
WAKE-UP is an investigator initiated European multicenter randomized controlled clinical trial of MRI based thrombolysis in acute stroke patients with unknown time of symptom onset, e.g.
- Trial name
- WAKE-UP (NCT01525290)
- Testing
- Alteplase
- Where
- 7 sites in Belgium, Denmark and 4 more
- Volunteers
- 501 people
- Sponsor
- Universitätsklinikum Hamburg-Eppendorf
Stable Angina, Coronary Stenosis
Optical Coherence Tomography to Investigate FFR-Guided DEB-only Elective Coronary Angioplasty
We aimed to evaluate feasibility and the 6-month angiographic and OCT results of FFR - guided use of paclitaxel-eluting balloons (Sequent Please™, B Braun) with provisional bare metal stenting for elective PCI of de novo coronary…
- Trial name
- OCTOPUS-2 (NCT02120859)
- Testing
- FFR - guided DEB angioplasty, Provisional bare metal stenting
- Where
- Germany
- Volunteers
- 50 people
- Sponsor
- University of Jena
Renal Cell Carcinoma, Renal Function Abnormal
The Cold Ischemia Robot-assisted Partial Nephrectomy
To establish evidence that cold ischemia, achieved through the use of ice slush, can improve the recovery from ischemia on the operated kidney in patients undergoing robot-assisted partial nephrectomy.
- Trial name
- NCT07326280
- Testing
- Cold ischemia robot-assisted partial nephrectomy, Warm ischemia robot-assisted partial nephrectomy
- Where
- China
- Volunteers
- 310 people
- Sponsor
- Sun Yat-sen University
Down Syndrome, Prenatal Stress
Amniotic Fluid Ischemia Modified Albumin as a Novel e Prenatal Diagnostic Marker for Down Syndrome
Down syndrome is the most common genetic disorder in the society that causes mental retardation. Today, screening tests (combined test, triple screening, ultrasonography and age) are performed for the diagnosis of down syndrome…
- Conditions
- Down Syndrome, Prenatal Stress, Cytokines
- Trial name
- NCT04293380
- Testing
- amniosyntesis
- Where
- Turkey (Türkiye)
- Volunteers
- 94 people, healthy volunteers welcome
- Sponsor
- Karadeniz Technical University
Coronary Artery Disease, Coronary Stenosis
Transit Time Flow Measurement in Coronary Surgery
Transit-time flowmetry (TTFM) allows grafts quality control during coronary artery bypass surgery by measuring the flow volume through them.
- Conditions
- Coronary Artery Disease, Coronary Stenosis, Coronary Bypass Graft Stenosis
- Trial name
- COLLATERAL (NCT06471062)
- Where
- Italy
- Volunteers
- 135 people, healthy volunteers welcome
- Sponsor
- Fondazione Policlinico Universitario Agostino Gemelli IRCCS
CHD - Coronary Heart Disease, Health Knowledge, Attitudes, Practice
mHealth Lifestyle Intervention on CHD Primary Prevention
Background: Coronary heart disease (CHD), the most prevalent type of cardiovascular disease among adults, has been identified as one of the chronic diseases which are epidemic in the world.
- Conditions
- CHD - Coronary Heart Disease, Health Knowledge, Attitudes, Practice, Health Behavior
- Trial name
- NCT03744650
- Testing
- "Care4Heart" programme
- Volunteers
- 160 people, healthy volunteers welcome
- Sponsor
- National University of Singapore
Myocardial Infarction
EMPACT-MI: A Study to Test Whether Empagliflozin Can Lower the Risk of Heart Failure and Death in People Who Had a Heart Attack (Myocardial Infarction)
This is a study in adults who had a heart attack (myocardial infarction). The purpose of this study is to find out whether a medicine called empagliflozin helps to lower the chances of having to go to the hospital for heart…
- Trial name
- NCT04509674
- Testing
- Empagliflozin
- Where
- 439 sites in United States, Argentina and 20 more
- Volunteers
- 6,522 people
- Sponsor
- Boehringer Ingelheim
ST Elevation Myocardial Infarction
Umbilical Cord Mesenchymal Stem Cell Improve Cardiac Function on ST-elevation Myocardial Infarction (STEMI) Patients
The goal of this clinical trial is to learn about the effectiveness of Umbilical Cord Mesenchymal Stem Cell (UC MSC) therapy in patients with STEMI against infarct myocardial size reduction and prevent the incidence of heart…
- Trial name
- NCT05935423
- Testing
- Umbilical Cord Mesenchymal Stem Cell transplantation
- Where
- Indonesia
- Volunteers
- 60 people
- Sponsor
- Universitas Indonesia
Acute Kidney Injury (Nontraumatic), Coronary Artery Disease
Contrast RISK (Reducing Injury Sustained by Kidneys)
Diagnostic and therapeutic cardiac catheterization procedures are important interventions to reduce the risk of death, avoid future cardiovascular events, and improve quality of life of people with heart disease.
- Trial name
- Contrast RISK (NCT03453996)
- Testing
- Intervention, Control
- Where
- 3 sites in Canada
- Volunteers
- 7,280 people
- Sponsor
- University of Calgary
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.