Clinical trials: Isolation
Well-Being, Psychological, Depressive Symptoms
e-Intervention Enhancing Mental Health in Adolescents
The e-Intervention Enhancing Mental Health in Adolescents (IMPROVA) study will co-design, test, evaluate, and facilitate the upscaling of a modular eHealth intervention platform that aims to improve mental health and wellbeing…
- Conditions
- Well-Being, Psychological, Depressive Symptoms, Social Isolation
- Trial name
- IMPROVA (NCT06556576)
- Testing
- IMPROVA Platform
- Volunteers
- 6,000 people, healthy volunteers welcome
- Sponsor
- Fundació Sant Joan de Déu
Social Activity
Oxytocin and Social Behavior Over the Lifespan
This study will investigate if intranasal oxytocin (a hormone naturally produced in the body) promotes motivation for, and engagement in, social activities in older adults.
- Trial name
- NCT00914953
- Testing
- oxytocin (Pitocin)
- Where
- United States
- Volunteers
- 41 people, healthy volunteers welcome
- Sponsor
- Claremont Graduate University
Social Isolation, Health Services Accessibility
Optimizing Medical Decisions and Care for Adult Orphans
This study aims to evaluate the effectiveness of a training program designed to improve clinicians' ability to care for adult orphans.
- Trial name
- NCT07465770
- Testing
- Caring for Adult Orphans
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Demyelinating Autoimmune Diseases, CNS
Epigenetic Evaluation of HAT/HDAC Activity in PBMC From Patients With Clinically Isolated Syndrome
The aim of the study is to compare the enzymatic activity of HATs and HDACs in peripheral blood mononuclear cell (PBMC) of patients with a clinically isolated syndrome (CIS group) and healthy controls (control group).
- Trial name
- EPIC (NCT02862301)
- Testing
- blood sample
- Where
- France
- Volunteers
- 55 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Social Isolation, Depression
Tertulias Social Isolation Women's Groups Study
This study will use a multi-level, community-engaged approach to implement "TERTULIAS" ("conversational gatherings" in Spanish).
- Trial name
- NCT04254198
- Testing
- TERTULIAS structured dialogue peer support groups
- Where
- 2 sites in United States
- Volunteers
- 241 people, healthy volunteers welcome
- Sponsor
- University of New Mexico
Clinically Isolated Syndrome
Glymphatic MRI in Clinically Isolated Syndrome
The brain possesses a system to get rid of unwanted substances, named Glymphatic System (GS). When this system is faulty, these accumulate, there is local inflammation, and progressive death of the cells.
- Trial name
- NCT06274671
- Testing
- Magnetic Resonance Imaging
- Where
- 2 sites in United Kingdom
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Exeter
Social Rejection, Attachement Style
Does Attachment Anxiety Moderate the Influence of Social Rejection on Alcohol Use Among Young Adults?
Research shows that heavy drinking patterns are linked to many harmful consequences including death, sexual assault, risky sexual behavior, and drug use.
- Trial name
- PSDCP-2 (NCT07905430)
- Testing
- Social Rejection Feedback, Social Acceptance
- Where
- United States
- Volunteers
- 152 people, healthy volunteers welcome
- Sponsor
- University of North Carolina, Wilmington
Women's Health
Isolated and Associated Effects of Physical Exercise and Estrogen Therapy on Climactercs Women
This study will investigate the isolated and the associated effect of estrogen therapy and physical exercise in the function, regulation and cardiovascular risk markers of 60 postmenopausal women, (45 - 60 years old).
- Trial name
- TRH01/989-7 (NCT01120665)
- Testing
- Estradiol valerate, Aerobic training, Control
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- University of Sao Paulo General Hospital
ISOLATION OF KLEB. by Culture on macConkey Agar, Antibiotic Sensitivity Testing of Different Antibiotics According to Clsi 25
Effect of Ceftazidime-Avibactam on Carbapenemase-Producing Klebsiella Pneumoniae
Specimen Collection : Clinical specimens included blood, urine, bronchoalveolar lavage fluid, wound, peritoneal fluid, and tracheal aspirate obtained from patients with suspected bacterial infections collected in dry sterile…
- Conditions
- ISOLATION OF KLEB. by Culture on macConkey Agar, Antibiotic Sensitivity Testing of Different Antibiotics According to Clsi 25, Effect of Ceftazidime-Avibactam on Carbapenemase-Producing Klebsiella Pneumoniae, Detection of Resistance Gene in Isolates Using Conventional Pcr
- Trial name
- NCT07369518
- Testing
- . - Genotypic detection of carbapenemase genes by conventional PCR.
- Where
- Egypt
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Sohag University
Isolated Impaired Fasting Glucose
Low-calorie Diet in Isolated Impaired Fasting Glucose
This study aims to evaluate the preliminary efficacy of a low-calorie diet (LCD) intervention in addressing the underlying pathophysiological abnormalities and improving fasting hyperglycemia among individuals with isolated…
- Trial name
- NCT06451055
- Testing
- Low-calorie diet, Routine dietary and physical activity habits
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Emory University
Social Isolation, Well-being
Effectiveness of a Communication Device in Home Care Services in Norway: Does Komp Make Older Adults Feel Happier, Safer and More Connected, and Able to Live Longer at Home.
This study is a field trial where "Komp" is implemented and tested as part of Oslo Municipality's home care services for older adults.
- Conditions
- Social Isolation, Well-being, Quality of Life, Mental Health
- Trial name
- BoVEL (NCT05919355)
- Testing
- Offer to try Komp
- Where
- 3 sites in Norway
- Volunteers
- 1,114 people, healthy volunteers welcome
- Sponsor
- Oslo Metropolitan University
the Use of Modern Technology Applications in Home Isolation
The Validity of Modern Mobile Applications in Management of COVID-19 Home Isolation Patients: a Survey for Health Care Professionals
In late 2019, a novel coronavirus, SARS-CoV-2, was identified as the causative agent of a cluster of pneumonia cases (COVID-19) in Wuhan, China. Clinical symptoms of COVID-19 may be mild or severe.
- Trial name
- NCT04548492
- Testing
- Survey
- Volunteers
- 175 people, healthy volunteers welcome
- Sponsor
- Ain Shams University
Social Isolation
AGE-ON 2.0: Expanding and Evaluating a Tablet Training Program for Older Adults
AGE-ON is a series of workshops developed by the Regional Geriatric Program central, based in Hamilton, Ontario. The goal of these workshops is to teach older adults with limited computer knowledge how to use tablet computers to…
- Trial name
- AGEON2 (NCT03472729)
- Testing
- AGE-ON Workshop
- Where
- Canada
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- McMaster University
Cerebral Ventriculomegaly
Prospective Follow-up of a Multicentric Cohort of Children With Prenatal Discovery of Mild Isolated Cerebral Ventriculomegaly. Evaluation at 2 and 5 Years.
Isolated uni or bilateral mild cerebral ventriculomegaly represents the most frequent "minor" cerebral anomalies discovered by antenatal echography.
- Trial name
- NCT00421772
- Where
- 2 sites in France
- Volunteers
- 245 people, healthy volunteers welcome
- Sponsor
- University Hospital, Angers
Oxytocin Deficiency, Hypopituitarism
Identification and Clinical Relevance of an Oxytocin Deficient State (Melatonin Study)
Oxytocin (OT) is a hypothalamic peptide that enters the peripheral circulation via the posterior pituitary gland. OT plays a key role in regulating appetite, psychopathology, prosocial behavior and sexual function.
- Conditions
- Oxytocin Deficiency, Hypopituitarism, Hypothalamic Obesity, Pituitary Dysfunction
- Trial name
- NCT05319301
- Testing
- Melatonin
- Where
- Spain
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Prostate Cancer
Immuno-molecular Approaches for Non-invasive Diagnosis of Prostate Cancer
The purpose of this study is to isolate and characterize tumor cells non-invasively from biological samples in patients with prostate cancer and demonstrate the ability to identify the presence and number of tumor cells before…
- Trial name
- PROSTA-PAP (NCT04702633)
- Testing
- Results obtained by biopsy and MRI results., Clinical data
- Where
- France
- Volunteers
- 127 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Dental Caries
Molecular Assessment of Oral Mutans Streptococcus Isolated From Different Patients
90 saliva samples will be isolated from patient who possess different ages and caries activity, attending outpatient clinic of October University of Modern Sciences and Arts.
- Trial name
- NCT03802669
- Testing
- oral mutans streptococcus
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- October University for Modern Sciences and Arts
Healthy
Optimizing Platelet Isolation (The Cell Study)
The research study is about blood cells (platelets) and their power houses (mitochondria). The investigators want to learn about their behavior in order to ensure that our laboratory procedures are generating optimal results.
- Trial name
- NCT04470505
- Where
- United States
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Arkansas Children's Hospital Research Institute
Social Isolation in Older Adults, Social Isolation or Loneliness
CAPABLE Care + Connect
In this evaluation scale-up research project, the investigators seek to test an implementation of CAPABLE on the infrastructure of home-based primary care for individuals who may experience social isolation and/or loneliness.
- Conditions
- Social Isolation in Older Adults, Social Isolation or Loneliness, Social Isolation, Quality of Life
- Trial name
- NCT07123298
- Testing
- CAPABLE Care + Connect - Open Label Pilot, CAPABLE Care + Connect - Pilot
- Where
- United States
- Volunteers
- 450 people, healthy volunteers welcome
- Sponsor
- Johns Hopkins University
Cerebrovascular Stroke, Cerebrovascular Accident
Does Isolated Robotic-Assisted Gait Training Improve Functional Status, Daily Living And Quality Of Life In Stroke?
Stroke is one of the major cause of morbidity and mortality and the leading cause of disability in adults all around the world. Stroke survivors can suffer several neurological impairments and deficits which have an important…
- Conditions
- Cerebrovascular Stroke, Cerebrovascular Accident, Cerebral Stroke
- Trial name
- NCT02759627
- Testing
- Robotic-Assisted Gait Training
- Volunteers
- 51 people, healthy volunteers welcome
- Sponsor
- Istanbul University