Clinical trials: Isolation
Dyslipidemias, Cardiovascular Risk Factor
Meta-analyses of Soy Protein and Its Food Sources for Cholesterol Reduction
Although soy protein has approved health claims in Canada and the US, and is recognized by major cardiovascular clinical practice guidelines for the reduction of cholesterol and risk of coronary heart disease (CHD), these claims…
- Conditions
- Dyslipidemias, Cardiovascular Risk Factor, Dysglycemia
- Trial name
- NCT04861545
- Testing
- Soy
- Where
- Canada
- Volunteers
- 1 people, healthy volunteers welcome
- Sponsor
- John Sievenpiper
Confinement and Isolation
A Counter Measure for the Effects of Immune and Microbiome Changes in Environments With Limited ANtigen Diversity (ICELAND-TWO)
There is evidence to indicate that the gut microbiota has an effect on mental well-being and stress behaviours. This is highly relevant to both life on earth and spaceflight missions, in which mental well-being is crucial to…
- Trial name
- ICELAND-2 (NCT03746145)
- Testing
- Bifidobacterium longum 1714
- Where
- Antarctica
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University Hospital Tuebingen
Anesthesia Awareness
ConsCIOUS2 Study of the Isolated Forearm Technique Commands
ConsCIOUS-2 is a multi-site study exploring the cognitive state of the Isolated Forearm Test (IFT) responder while under anesthetic.
- Trial name
- NCT03503357
- Testing
- IFT Testing1, IFT Testing 2, IFT Testing 3
- Where
- 11 sites in United States, Australia and 5 more
- Volunteers
- 344 people, healthy volunteers welcome
- Sponsor
- University of Wisconsin, Madison
Primary Immune Thrombocytopenic Purpura, Amegakaryocytic Aplasia
Ultrasound to Detect Splenomegally in Patients With Isolated Thrombocytopenia
Investigate prevalence of splenomegally in patients with isolated thrombocytopenia. Asess effect of splenomegally in clinical picture ,Complication, treatment response and disease outcome To explain possible causes of…
- Conditions
- Primary Immune Thrombocytopenic Purpura, Amegakaryocytic Aplasia, Unilineage Myelodysplastic Syndrome ( Megakaryocyte Dysplasia), Lymphoproliferative Disorder With Secondary ITP
- Trial name
- NCT07182760
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Assiut University
Social Isolation
ENRED@TE. Social Support in Southern Spain. Interventional Study
The main objective to be achieved is to find out if the perceived social support, the perceived loneliness, the perceived social isolation and the family support of those over 65 years of age improve after participating in the…
- Trial name
- NCT04567940
- Testing
- ENRED@TE: Behavioural multicomponent intervention
- Where
- Spain
- Volunteers
- 210 people, healthy volunteers welcome
- Sponsor
- Maimónides Biomedical Research Institute of Córdoba
Typical Atrial Flutter, Risk Factors With Future Development of Atrial Flutter
Pulmonary Vein Isolation To Reduce Future Risk Of Atrial Fibrillation In Patients Undergoing Typical Flutter
The purpose is to compare long term occurrence of atrial arrhythmias including atrial fibrillation (AF) and thromboembolic complications including cerebrovascular events (CVE) in patients with typical atrial flutter (AFLT)…
- Trial name
- REDUCE AF (NCT01710150)
- Testing
- CTI ablation alone, CTI ablation and Pulmonary vein isolation (PVI)
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Loneliness, Social Isolation in Older Adults
The ALIVE-Project: Activity, Life Satisfaction, Inclusion, Vitality, Elderly Women
Many older women live alone and may experience loneliness, reduced social participation, and declining physical health. Regular physical activity can improve health and independence, but it is not known whether exercising in a…
- Conditions
- Loneliness, Social Isolation in Older Adults, Physical Inactivity, Healthy Ageing
- Trial name
- ALIVE (NCT07789080)
- Testing
- Supervised Group Exercise in Fitness Clubs, Individual exercise
- Where
- Norway
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Norwegian School of Sport Sciences
Sleep, Alertness
Operational Evaluation of a Photic Countermeasure to Improve Alertness, Performance, and Mood During Nightshift Work on a 105-day Simulated Human Exploration Mission to Mars
The success of human expedition missions critically depend on the ability of the crew to be alert and maintain high levels of cognitive function while operating complex, technical equipment.
- Conditions
- Sleep, Alertness, Fatigue
- Trial name
- Mars 105 (NCT01169233)
- Testing
- Bright Light Box
- Where
- Russia
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Recession, Gingival
Clinical Evaluation of Laterally Closed Tunnel Technique Versus Coronally Advanced Flap Combined With Connective Tissue Graft for the Treatment of Isolated RT2 Gingival Recession
The aim of this study is to evaluate reduction of recession depth using lateral closed tunnel technique versus CAF technique using connective tissue graft in single RT2 gingival recession cases.
- Trial name
- NCT05823415
- Testing
- Laterally Closed Tunnel with CTG, CAF with CTG
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- British University In Egypt
Multiple Sclerosis, Clinically Isolated Syndrome
Visual Processing Speed and Objective Analysis of Ocular Movements in Multiple Sclerosis
This project aims to analyze ocular motility problems, visual processing speed and microperimetry, and their relationship with consolidated retinal structural biomarkers (optical coherence tomography, OCT) in patients with…
- Conditions
- Multiple Sclerosis, Clinically Isolated Syndrome, Relapsing Remitting Multiple Sclerosis, Progressive Multiple Sclerosis
- Trial name
- NCT05706220
- Testing
- Eye tracking, Microperimetry, Optical coherence tomography (OCT)
- Where
- Spain
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Instituto Universitario de Oftalmobiología Aplicada (Institute of Applied Ophthalmobiology) - IOBA
Cartilage Injury, Osteochondritis Dissecans
A Randomized Controlled Trial Comparing Chondro-Gide® to Microfracture Alone for Treatment of Knee Cartilage Defects.
The purpose of this study is to evaluate the safety and effectiveness of using Chondro-Gide® collagen membrane either sutured or glued compared to microfracture alone in the treatment of symptomatic cartilage defects of the knee.
- Trial name
- NCT02993510
- Testing
- Microfracture, Chondro-Gide sutured, Chondro-Gide glued
- Where
- 7 sites in Germany
- Volunteers
- 67 people, healthy volunteers welcome
- Sponsor
- Geistlich Pharma AG
Coronary Artery Ectasia
Effect of Diltiazem on Coronary Artery Ectasia
Coronary artery ectasia (CAE) has been defined as localized or diffuse dilatation of epicardial coronary arteries more than 1.5 fold of adjacent normal segments.
- Trial name
- NCT02024919
- Testing
- intracoronary administration of diltiazem, intracoronary injection of 5 mL saline
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ankara University
Fissure Sealant, Rubberdam
Clinical Evaluation Fissure Sealants Applied With Different Isolation Techniques
The aim of this clinical study was to evaluate the effects of different isolation methods and material filler ratios on the retention rates of two different fluoride-containing fissure sealants over an 18-month period.
- Conditions
- Fissure Sealant, Rubberdam, Isolation
- Trial name
- NCT07110701
- Testing
- Retention of the fissure sealants evaluated
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Izmir Katip Celebi University
Social Isolation, Mental Status Change
Effects of Arts Engagement on Physical Performance, Cognition, Social Isolation, and Self-Perception in Older Adults
The purpose of this community-engaged project is to examine how taking part in different arts (dance \& music), compared to control (no arts) affects older adults' Health-Related Quality of Life (HRQoL using the Short Form-20(SF)…
- Conditions
- Social Isolation, Mental Status Change, Cognitive Impairment, Physical Activity
- Trial name
- SHARe (NCT04281654)
- Testing
- Active Social Conversation
- Where
- United States
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- George Mason University
Radiologically Isolated Syndrome, Epstein-Barr Virus Infections
Environmental Risk Factors in Multiple Sclerosis Development: Epidemiological Study of EBV Infection and Vitamin D Deficiency in RIS Patients
This is an ancillary study using samples collected in the ProBioRIS cohort (NCT06395662). The aim of the project is to highlight new biomarker candidates to assess the risk of conversion to clinically definite multiple sclerosis…
- Trial name
- RIS - EBVD (NCT07256431)
- Testing
- Antibiody titration
- Where
- France
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nīmes
Social Isolation, Loneliness
COVID-19 and Social Isolation and Loneliness Trial
Social isolation and loneliness worsen older peoples' quality of life, risk of dementia, and contributes to 45,000 deaths/year in Canada - as much as smoking.
- Conditions
- Social Isolation, Loneliness, Geriatric
- Trial name
- SIL (NCT05228782)
- Testing
- HOW R U? Intervention
- Where
- Canada
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Health Behavior, Eating Behavior
Eating Habits of Adults During the Quarantine
The aim of this study is to assess the changes in the dietary habits of adults spending most of their time in their homes due to the Coronavirus (COVID-19) outbreak.
- Trial name
- NCT04339842
- Testing
- Assessment of Dietary Changes in Adults in the Quarantine
- Where
- Cyprus
- Volunteers
- 673 people, healthy volunteers welcome
- Sponsor
- Eliz Arter
Breast Cancer, Prostate Cancer
Evaluation Protocols for Isolation of Analytes From Urine for Future Oncology Applications
The aim of this study is to evaluate and optimize protocols for the isolation and analysis of analytes in urine (cell-free nucleic acids, extracellular vesicles and proteins).
- Conditions
- Breast Cancer, Prostate Cancer, Urine, Liquid Biopsy
- Trial name
- URODETECT-WP1 (NCT05453604)
- Testing
- Colli-Pee UAS devices
- Where
- Belgium
- Volunteers
- 105 people, healthy volunteers welcome
- Sponsor
- Novosanis NV
Social Isolation
Refugee Mental Health and Wellness Pilot Study
This pilot study will develop and examine the acceptability of a Community Navigator program of support for 10-24 older adult immigrant participants receiving services at a refugee-serving organization based in Southern…
- Trial name
- NCT05031247
- Testing
- Wellbeing Program
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of California, Los Angeles
Loneliness, Social Isolation
Decreasing Loneliness in Older Adults
The purposes of this study are: (1) decrease loneliness and social isolation and increase social competence and social integration of older adults experiencing loneliness; (2) examine an intervention process grounded in a…
- Trial name
- I-SOCIAL (NCT01842984)
- Testing
- I-SOCIAL intervention
- Where
- Israel
- Volunteers
- 74 people, healthy volunteers welcome
- Sponsor
- Tel Aviv University