Clinical trials: Isolation
Retention, Time
Efficacy and Retention of Sealants Placement Using Two Isolation Systems
The trial aimed to evaluate the sealant retention, patient's preference and chair time needed during pit and fissure sealant placement under two isolation techniques [Dryshield system (DS) and cotton roll isolation (CRI)] in a…
- Conditions
- Retention, Time, Patient Preference
- Trial name
- NCT05749991
- Testing
- Dryshield, Cotton roll isolation
- Where
- Kuwait
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Kuwait University
Cognitive Decline, Social Isolation
Evaluation of the Wits Workout Wellness Program for Older Adults
About 11% of the U.S. older adult population is at risk for or suffers from subjective cognitive decline. While some factors such as genetics and habitual physiological changes that affect brain health cannot be changed, research…
- Conditions
- Cognitive Decline, Social Isolation, Health Behaviors, Self Efficacy
- Trial name
- NCT04928885
- Testing
- Wits Workout Program, Control Group that receives intervention after the study
- Where
- United States
- Volunteers
- 285 people, healthy volunteers welcome
- Sponsor
- University of Illinois Chicago
Alzheimer Disease, Dementia
Defining the Genetic Etiology of Alzheimer's Disease in the Faroe Islands
The investigators established the Faroese Alzheimer's Cohort with the aim to unravel genetic and environmental factors that influence the risk and/or susceptibility of Alzheimers disease (AD).
- Trial name
- NCT03628404
- Where
- Faroe Islands
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Faroese Hospital System
Isolation, Social
Reciprocal Benefit by Intergenerational Meetings
The investigators want to set up an experiment that allows a reciprocal benefit to 2 fragile populations: isolated seniors and disadvantaged children.
- Trial name
- Part'Ages (NCT05551234)
- Testing
- Regular exchanges
- Where
- France
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Centre Hospitalier Universitaire de Nice
Loneliness, Social Support
The Social Engagement Project: Addressing Isolation with Women Affected by Violence
The goal of this study is to test a pilot intervention aimed at improving social connectedness among women affected by gender-based violence in a resource-restricted, urban context.
- Conditions
- Loneliness, Social Support, Social Isolation
- Trial name
- SEP (NCT05574192)
- Testing
- Social Engagement Intervention
- Where
- Canada
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of British Columbia
Atrial Fibrillation, Hypertension, Pulmonary
Safety Procedure Pulmonary Artery Denervation in Addition to Pulmonary Vein Isolation Combined With Ganglionated Plexi Ablation in Patients With Persistent Atrial Fibrillation and Pulmonary Hypertension
Some patients with a long history of AF develops PH "reactive" type with an increase in pulmonary vascular resistance due to vasoconstriction or structural changes of the vascular wall.
- Conditions
- Atrial Fibrillation, Hypertension, Pulmonary, Heart Diseases, Arrhythmias, Cardiac
- Trial name
- NCT02298244
- Testing
- PV isolation + GP Ablation, PV isolation + GP ablation + Pulmonary GP ablation
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Krasnoyarsk Regional Hospital
Isolation, Social, Virtual Reality
Brain Changes in Response to Long-Duration Isolation and Confinement
This study investigates the time course and magnitude of eight months of isolation and confinement in a spaceflight analog facility on brain changes and cognitive performance.
- Conditions
- Isolation, Social, Virtual Reality, Spatial Navigation
- Trial name
- BRAIVE (NCT04532866)
- Testing
- Isolation and Confinement
- Where
- Russia
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Charite University, Berlin, Germany
Physical Inactivity, Cognitive Decline
Developing and Assessing an Innovative Exergaming Technology for Older Adults Living in Long-term Care Homes
Residents living in long-term care (LTC) homes spend up to 75% of their day in sedentary, socially withdrawn situations which increases their risk for depression, dementia, decreased functional status and increased care costs.
- Conditions
- Physical Inactivity, Cognitive Decline, Aging, Social Isolation
- Trial name
- MouvMat (NCT05130203)
- Testing
- MouvMat Exergaming, Standard Recreational Programming
- Where
- 2 sites in Canada
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Toronto
Relapse
Comparison of Efficiency and Effectiveness of Two Types of Bonded Orthodontic Retainers: an RCT.
Comparson of efficiency and effectiveness of twisted/coaxial and linked retainers, placed under relative versus absolute isolation.
- Trial name
- NCT05250765
- Testing
- Twistflex retainer, Orthoflex retainer
- Where
- Belgium
- Volunteers
- 114 people, healthy volunteers welcome
- Sponsor
- University Hospital, Ghent
Parkinson Disease, REM Sleep Behavior Disorder (iRBD)
Study of Sleep Disorders in Prodromal and Definite Parkinsons Disease
Multicenter controlled study of sleep disorders in isolated REM Behavior Disorder and Parkinson\'s disease (SOMPARK)
- Trial name
- SOMPARK (NCT06582121)
- Testing
- Polysomnography
- Where
- 6 sites in France
- Volunteers
- 457 people, healthy volunteers welcome
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Endometriosis
Somatic Stem Cells in Endometriosis
Human endometrium is a very dynamic tissue characterized by cyclical process of proliferation, differentiation and cellular shedding as part of each menstrual cycle. This issue suggests the presence of somatic stem cells.
- Trial name
- NCT01412138
- Testing
- genetic analysis
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Igenomix
Physiological Stress, Cognitive Dysfunction
DEEPTIME: Human Adaptation in Time Underground Isolation
The objectives of this scientific expedition are: a/ Evaluation of temporal cognitive perception and collective synchronization in a temporally anomalous universe (underground environment), b/ Influence of group living on the…
- Conditions
- Physiological Stress, Cognitive Dysfunction, Sleep
- Trial name
- DEEPTIME (NCT05603780)
- Testing
- exploratory protocol
- Where
- France
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University Hospital, Caen
Mental Health Wellness 1, Sedentary Behavior
Health Parameters of University Students After Pandemic Isolation
The COVID-19 pandemic caused by the SARS-CoV-2 coronavirus represents threats to global health and economy. The high pathogenesis of SARS-CoV-2 extent that the Mexican government declared a national health emergency, agreeing to…
- Trial name
- NCT05282537
- Testing
- In person academic activities
- Where
- Mexico
- Volunteers
- 280 people, healthy volunteers welcome
- Sponsor
- Universidad Autonoma de Baja California
Paroxysmal Atrial Fibrillation
Cryoballoon PVI With PWI Versus PVI Alone In Patients With PAF
Cryoballoon ablation has emerged as a safe and effective strategy for treatment of atrial fibrillation (AF) for which it has recently received a 'first-line' therapy indication by the FDA.
- Trial name
- NCT05296824
- Testing
- Cryoballoon ablation for the treatment of atrial fibrillation
- Where
- 4 sites in United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Sacramento EP Research
Social Isolation, Loneliness
Intergenerational Program for Social Isolation and Loneliness in Older Adults Discharged From the Emergency Department
Social isolation and loneliness worsens older adults' risk of dementia, quality of life, and death as much as smoking. Older adults are more likely to use emergency services and are also more likely to experience social isolation…
- Conditions
- Social Isolation, Loneliness, Geriatric
- Trial name
- SIL (NCT05998343)
- Testing
- Intergenerational HOW R U?, Same-Generation Peer Support HOW R U?
- Where
- Canada
- Volunteers
- 141 people, healthy volunteers welcome
- Sponsor
- Mount Sinai Hospital, Canada
Gingival Recession, Localized
The Laterally Closed Tunnel Versus Modified Coronally Advanced Tunnel for Mandibular Anterior Gingival Recession Defects
The aim of this study is to comparatively evaluate the advantages of LCT with SCTG over MCAT with SCTG for coverage of deep isolated mandibular anterior recession.
- Trial name
- NCT04198376
- Testing
- Group A The Laterally Closed Tunnel Technique with SCTG, Group B Modified Coronally Advanced Tunnel Technique with SCTG.
- Where
- India
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Krishnadevaraya College of Dental Sciences & Hospital
Trisomy 21, Trisomy 18
Development of Non-invasive Prenatal Screening Test for Microdeletions Based on Fetal DNA Isolated From Maternal Blood
The purpose of this study is to collect maternal blood samples from pregnant women carrying a fetus with a confirmed diagnosis of chromosomal abnormality or genetic disorder including microdeletions in order to further develop a…
- Conditions
- Trisomy 21, Trisomy 18, Trisomy 13, Sex Chromosome Abnormalities
- Trial name
- MAPS (NCT01852708)
- Where
- 9 sites in United States, Spain and 1 more
- Volunteers
- 1,059 people, healthy volunteers welcome
- Sponsor
- Natera, Inc.
COVID-19
Plasma Immunity of Mild SARS-CoV-2 Omicron and Delta Pandemic in Thailand
The investigators assessed the effect of treatment for COVID and immunity of the volunteers who admitted to the home isolation.
- Trial name
- NCT05328479
- Where
- Thailand
- Volunteers
- 5,181 people, healthy volunteers welcome
- Sponsor
- Mahidol University
Social Cognition, Healthy Aging
Immersive Group Dance in Virtual Reality and Perceived Social Cohesion in Older Adults
This is a two-arm, parallel-group randomized controlled trial designed to evaluate the effects of an immersive virtual reality (VR)-based group dance program on perceived social cohesion among community-dwelling older adults…
- Conditions
- Social Cognition, Healthy Aging, Loneliness, Social Isolation
- Trial name
- VR-GD-COHESION (NCT07850479)
- Testing
- Immersive VR Group Dance Program, Conventional Light Physical Activity Program
- Where
- China
- Volunteers
- 180 people, healthy volunteers welcome
- Sponsor
- Islamic Azad University, Sanandaj
Schizophrenia and Related Disorders
Social Isolation and Aging in Schizophrenia
Individuals diagnosed with schizophrenia and related psychotic disorders (SZ) exhibit a markedly elevated risk of premature mortality, with a 10-20-year shorter lifespan relative to the general population.
- Trial name
- SIAS (NCT07419321)
- Where
- 4 sites in United States, Netherlands and 2 more
- Volunteers
- 650 people, healthy volunteers welcome
- Sponsor
- Icahn School of Medicine at Mount Sinai