Clinical trials: Isolation
Dissection of the Superior Mesenteric Artery
Dissection of the Superior Mesenteric Artery
This study aims to evaluate the prognosis of patients with spontaneous solitary dissection of superior mesenteric artery (SIDSMA) who have been treated with stents.
- Trial name
- NCT05171842
- Testing
- Observe the prognosis after stent implantation
- Where
- China
- Volunteers
- 136 people
- Sponsor
- First Affiliated Hospital of Zhejiang University
Laparoscopic Surgery
Laparoscopic Splenectomy in Isolated High Grades Splenic Injuries
Background: Trauma laparoscopic splenectomy has no defined reasons. Compared trauma patient characteristics and results with laparoscopic and open splenectomies.
- Trial name
- NCT04329845
- Testing
- open splenectomy, laparoscopic splenectomy for splenic injury in trauma
- Volunteers
- 2 people
- Sponsor
- Zagazig University
Chronic Poststernotomy Pain
Bilateral Pecto-Intercostal Fascial Plane Block for Prevention of Chronic Poststernotomy Pain After CABG
This single-center, prospective, parallel-group randomized controlled trial will evaluate whether adding ultrasound-guided bilateral single-shot pecto-intercostal fascial plane block (PIFB) to standard multimodal systemic…
- Trial name
- NCT07882836
- Testing
- Pecto-Intercostal Fascial Plane Block, Standardized Multimodal Systemic Analgesia
- Where
- Turkey (Türkiye)
- Volunteers
- 180 people
- Sponsor
- Izmir Katip Celebi University
Paroxysmal Atrial Fibrillation
Adenosine vs AF Termination for Paroxysmal AF Ablation
This study investigates impact of adenosine versus AF inducibility and subsequent termination on the acute and long-term outcome of paroxysmal AF ablation.
- Trial name
- NCT02238392
- Testing
- Adenosine test, Termination of AF
- Where
- Germany
- Volunteers
- 150 people
- Sponsor
- Johannes Gutenberg University Mainz
Social Isolation, Loneliness
Connection for Latinos Caring for a Loved One With Dementia
The purpose of this research study is to culturally adapt a personalized intervention for Hispanic/Latino caring for a loved one with significant memory problems.
- Trial name
- NCT04593628
- Testing
- Connect for Caregivers
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- University of Rochester
Atrial Flutter Typical
Cryoballoon Ablation as First Line Treatment of Atrial Flutter
Current guidelines recommend radiofrequency catheter ablation of the cavotricuspid isthmus as treatment for symptomatic/drug-refractory atrial flutter, in spite of the fact that recurrences of flutter and incidence of…
- Trial name
- CRAFT (NCT03401099)
- Testing
- Radiofrequency ablation of CTI, Cryoballoon PVI
- Where
- 10 sites in Switzerland, United Kingdom
- Volunteers
- 113 people
- Sponsor
- Liverpool Heart and Chest Hospital NHS Foundation Trust
Paroxysmal Atrial Fibrillation
High Power Short Duration Ablation Compared to Moderate Power Long Duration Ablation for Pulmonary Vein Isolation
High Power Short Duration Ablation Compared to Moderate Power Long Duration Ablation for Pulmonary Vein Isolation: safety and acute procedural outcome
- Trial name
- NCT05959798
- Testing
- High power short duration ablation
- Where
- Germany
- Volunteers
- 204 people
- Sponsor
- Deutsches Herzzentrum Muenchen
Multiple Sclerosis (MS), Multiple Sclerosis (MS) Relapsing Remitting
Social Cognition in Multiple Sclerosis, From a Study of Eye Movement and Gaze Strategies Using Video-oculography
This study aims to: analyze prospectively the prevalence of subclinical oculomotor disorders (OMDs) in different phenotypes of Multiple Sclerosis (MS) and to study correlations with brain MRI T2 data.
- Conditions
- Multiple Sclerosis (MS), Multiple Sclerosis (MS) Relapsing Remitting, Multiple Sclerosis (MS) Primary Progressive, Multiple Sclerosis (MS) Secondary Progressive
- Trial name
- EYE-SEP (NCT04705610)
- Testing
- Video-oculography / Social cognition tasks / Neuropsychological evaluations
- Where
- Monaco
- Volunteers
- 76 people, healthy volunteers welcome
- Sponsor
- Association de Recherche Bibliographique pour les Neurosciences
Hypertension, Systolic, Stiffness, Aortic
Sympathetic Regulation of Large Artery Stiffness in Humans With ISH
Stiffening of your blood vessels, particularly the large vessels from your heart (called the aorta and carotids) you age contributes to the development of cardiovascular disease (CVD) such as heart attack and stroke.
- Trial name
- SELECT (NCT04423627)
- Testing
- Clonidine, Hydrochlorothiazide
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Atrial Fibrillation
CLOSE to CURE Study
Title: CLOSE-guided pulmonary vein isolation (PVI) as Cure for Paroxysmal Atrial Fibrillation ('CLOSE to CURE' study) Design: This is a prospective, observational, single-center, unblinded, clinical 3-year study.
- Trial name
- NCT02925624
- Testing
- Pulmonary vein isolation
- Where
- Belgium
- Volunteers
- 105 people
- Sponsor
- AZ Sint-Jan AV
Acute Kidney Injury, Coronary Artery Disease
Renal Doppler Indices for Predicting Acute Kidney Injury After Isolated CABG
Acute kidney injury can occur after coronary artery bypass grafting (CABG). This prospective, single-center observational study will evaluate whether two measurements obtained from renal Doppler ultrasound-the renal augmented…
- Trial name
- NCT07821983
- Testing
- Renal Doppler Ultrasonography
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Bursa Yuksek Ihtisas Training and Research Hospital
Molybdenum Cofactor Deficiency, Isolated Sulfite Oxidase Deficiency
A Natural History Study of Molybdenum Cofactor and Isolated Sulfite Oxidase Deficiencies
Primary objective: Characterize the natural history of MoCD type A in terms of survival Secondary objectives: 1. Evaluate blood and urine for biochemical markers 2.
- Trial name
- NCT01735188
- Where
- 32 sites in United States, Canada and 12 more
- Volunteers
- 65 people
- Sponsor
- Origin Biosciences
Persistent Atrial Fibrillation
Comparison of Hybrid Ablation and Pulmonary Vein Isolation Alone vs Hybrid Ablation With PVI Plus Catheter Ablation
The overall objective of the study is to compare and assess the clinical outcomes of the standard of care hybrid ablation using epicardial ablation in conjunction with endocardial PVI alone versus epicardial ablation in…
- Trial name
- NCT02344394
- Testing
- Medtronic Cryoballoon, Thermocool Catheter, nContact
- Where
- United States
- Sponsor
- Wake Forest University Health Sciences
Loneliness, Social Isolation
Virtual Yoga for Social Isolation and Loneliness in Rural Veterans
The overarching goal of this project is to decrease social isolation and loneliness through increased awareness and uptake of virtual yoga group classes among rural Veterans.
- Trial name
- NCT05431166
- Testing
- Virtual Yoga at First 8 weeks, Virtual Yoga at Second 8 weeks
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Oregon Health and Science University
Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia
HLA-Compatible Related or Unrelated Donors With CD34+ Enriched, T-cell Depleted Peripheral Blood Stem Cells Isolated by the CliniMACS System in the Treatment of Patients With Hematologic Malignancies
The purpose of this study is to find out the effects of using a system called CliniMACS to remove Tcells from blood stem cells. Removing T-cells may help stop a side effect called Graft-Versus-Host Disease (GVHD).
- Conditions
- Acute Lymphoblastic Leukemia, Acute Myelogenous Leukemia, Myelodysplastic Syndrome, Multiple Myeloma
- Trial name
- NCT01119066
- Testing
- total body irradiation, Thiotepa, Cyclophosphamide
- Where
- United States
- Volunteers
- 422 people
- Sponsor
- Memorial Sloan Kettering Cancer Center
Social Isolation, Health Services Accessibility
Optimizing Medical Decisions and Care for Adult Orphans
This study aims to evaluate the effectiveness of a training program designed to improve clinicians' ability to care for adult orphans.
- Trial name
- NCT07465770
- Testing
- Caring for Adult Orphans
- Where
- Taiwan
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Chang Gung University
Healthy Volunteer
Emotional, Social, Cognitive and Behavioral Sequalae of the COVID-19 Pandemic
Background: COVID-19 has caused a high rate of deaths. The steps taken to control its spread have caused social isolation, changes in lifestyle, economic turmoil, and increased work-related stress.
- Trial name
- NCT04823988
- Where
- United States
- Volunteers
- 2,086 people
- Sponsor
- National Institute of Mental Health (NIMH)
Chronic Myeloproliferative Disorders, Leukemia
Interleukin-12 Followed by Interferon Alfa in Treating Patients With Advanced Cancer
Phase I trial to study the effectiveness of combining interleukin-12 and interferon alfa in treating patients who have residual, recurrent, or metastatic malignant melanoma or other advanced cancer that has not responded to…
- Conditions
- Chronic Myeloproliferative Disorders, Leukemia, Lymphoma, Multiple Myeloma and Plasma Cell Neoplasm
- Trial name
- NCT00003451
- Testing
- recombinant interferon alfa, recombinant interleukin-12
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- National Cancer Institute (NCI)
Paroxysmal Atrial Fibrillation
Compared With 2 Different Ablation Strategies Clinical Outcome for Treating Patients With Paroxysmal Atrial Fibrillation
Atrial fibrillation (AF) is the most serious atrial electrical activity disorders, is also one of the common tachyarrhythmias.Circumferential pulmonary Vein Isolation (CPVI) is considered to be the cornerstone of paroxysmal…
- Trial name
- NCT03190395
- Testing
- CPVI Group, CPVI+LARA Group
- Where
- China
- Volunteers
- 120 people
- Sponsor
- Zhujiang Hospital
Heart Failure
Harvest, Isolation and Culture of Cardiac Stem Cells From Endomyocardial Biopsies
The purpose of this study is to determine whether the harvest, isolation and culture of cardiac stem cells from endomyocardial biopsies is feasible.
- Trial name
- NCT01576757
- Where
- United States
- Sponsor
- University of Louisville
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