Clinical trials: Isthmocele
Reproductive Issues, Cesarean Section; Dehiscence
Hysteroscopic Isthmocele Repair on IVF Outcome
Hysteroscopic Isthmocele repair on IVF outcome It aims to assesse the efficacy of Hysteroscopic CS scar defect repair on the clinical pregnancy rate after embryo transfer.
- Conditions
- Reproductive Issues, Cesarean Section; Dehiscence, Intrauterine Disorder
- Trial name
- NCT05590104
- Testing
- Hysteroscopic CS scar defect repair
- Where
- 2 sites in United Arab Emirates
- Volunteers
- 50 people
- Sponsor
- HealthPlus Fertility Center
Cesarean Scar Defect
Impact of a Bladder Flap on Cesarean Scar Niche Development
The goal of this trial is to examine if the completion or omission of a bladder flap impacts the location and formation of cesarean scar niche in women undergoing primary cesarean section.
- Trial name
- B-FIND (NCT07634679)
- Testing
- Bladder flap formation
- Where
- 2 sites in United States
- Volunteers
- 338 people
- Sponsor
- Montefiore Medical Center
Isthmocele, Uterine Scar Defects
Cesarean Scar Defects After Uterine Closure by Double-layer Barbed or Smooth Suture
Late sequelae of a cesarean section related to a uterine scar defects include gynecological symptoms and obstetric complications.
- Conditions
- Isthmocele, Uterine Scar Defects, Cesarean Section Complications, Uterine Niche
- Trial name
- NCT04825821
- Testing
- Clinical and ultrasonographic assessment
- Where
- Italy
- Volunteers
- 247 people, healthy volunteers welcome
- Sponsor
- Ospedale Policlinico San Martino
Uterine Scar
Comparison Of Suture Materials on Sectio Scars (COSMOSS)
This multicenter prospective randomized controlled trial aims to investigate the ishtmocele rates after c-section delivery depending on using different suture materials for the uterine closure.
- Trial name
- COSMOSS (NCT05096910)
- Testing
- Uterine Closure with monofilament or polyfilament suture materials
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Uludag University
Cesarean Section; Dehiscence, Cesarean Wound; Dehiscence
Isthmocele After Endometrial and Non-endometrial Suturing in Cesarean Section
This study compares the effect of two techniques of uterine closure, with or without endometrial suturing on isthmocele development after cesarean section.
- Trial name
- NCT04198324
- Testing
- Closure of the uterus with endometrium at the time of cesarean, Closure of the uterus without endometrium at the time of cesarean
- Where
- Turkey (Türkiye)
- Volunteers
- 170 people
- Sponsor
- Kocaeli University
Wound Heal, Cesarean Section Complications
The Effect of Suturing Material on Scar Healing
We want to compare the effects of 2 suture materials (monofilament and multifilament) on healing of the uterine scar after a cesarean delivery.
- Conditions
- Wound Heal, Cesarean Section Complications, Cesarean Wound Disruption, Suture Related Complication
- Trial name
- NCT03968783
- Testing
- Monofilament suture, Multifilament suture
- Where
- Turkey (Türkiye)
- Volunteers
- 95 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Isthmocele, Post-menstrual Spotting Bleeding
Can Intrauterine Levonorgestrel Releasing Device Be a Treatment Option for Postmenstrual Spotting in Isthmocele
it was planned to investigate the treatment effect of levonorgestrel releasing intrauterine device in patient with isthmocele who were suffering from postmenstrual spotting bleeding and who had no desire for fertility.
- Conditions
- Isthmocele, Post-menstrual Spotting Bleeding, Pelvic Pain
- Trial name
- NCT04872244
- Testing
- usage of mirena ( levonorgestrel releasing intrauterine device) in isthmocele, Levonorgestrel Drug Implant Product
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people
- Sponsor
- Gaziosmanpasa Research and Education Hospital
Anteversion of Uterus, Retroflex Uterus
Relation Between Position of the Uterus (Anteversion or Retroversion Flexion) and Degree of Cesarean Scar Niche
This study aims to determine the association between the size of caesarean scar niche and uterine position in childbearing women.
- Conditions
- Anteversion of Uterus, Retroflex Uterus, CSD
- Trial name
- NCT06475924
- Testing
- Caesarean scar defect evlauation by ultraosund
- Where
- Egypt
- Volunteers
- 86 people
- Sponsor
- Ain Shams University
Isthmocele
Frequency of Isthmocele Following Single- Vs Double-layer Uterine Closure.
The main objective of this study is to compare the frequency of isthmocele after caesarean section according to the type of hysteroraffia performed (single or double layer suture).
- Trial name
- NCT06708234
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Lorenza Driul
Laparoscopic or Robotic Metroplasty
Clinical Outcome of Laparoscopic or Robotic Metroplasty for Uterine Isthmocele
To evaluate the clinical outcomes of conventional or robotic - laparoscopic metroplasty for uterine isthmocele with the aid of a bending probe.
- Trial name
- NCT04414670
- Testing
- C/S
- Where
- Taiwan
- Volunteers
- 20 people
- Sponsor
- Far Eastern Memorial Hospital
Suture, Complication, Istmocel
The Effect of Suture Materials With Different Absorption Times on Isthmocele: Prospective Randomized Study
This study aims to investigate the effect of suture materials with different absorption times on istmocel.
- Trial name
- NCT04455321
- Testing
- Suture materials effect on istmocel
- Where
- Turkey (Türkiye)
- Volunteers
- 102 people
- Sponsor
- Baskent University
Isthmocele
Laparoscopic Isthmocele Repair
To evaluate postoperative outcomes in patients with isthmocele undergoing laparoscopic repair, comparing the efficacy of V-LocTM 180 and Polyglactin 910 Vicryl sutures.
- Trial name
- NCT06918275
- Testing
- Laparoscopic isthmocele repair using V-LocTM 180 barbed suture, Laparoscopic isthmocele repair using Polyglactin 910 vicryl suture
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Isthmocele, Cesarean Scar Diverticula
Comparing Decidual Inclusion vs. Exclusion in Uterine Suture Techniques During Cesarean Section to Improve Scar Thickness and Reduce Isthmocele Risk in Primiparous Women
This study compares two ways of closing the uterus during cesarean delivery. In one group, the decidual layer near the uterine cavity is included in the suture. In the other group, this layer is left out.
- Trial name
- DISSUC (NCT07608874)
- Testing
- Single-Layered Non-Locked Closure with Decidual Inclusion, Single-Layered Non-Locked Closure with Decidual Sparing
- Where
- Switzerland
- Volunteers
- 374 people
- Sponsor
- Kantonsspital Baden
Dysfunctional Uterine Bleeding
Misotac vs Combined Oral Contraceptive Pill in the Treatment of Symptomatic Isthmocele
Isthmocele is a growing concern as a cause of abnormal uterine bleeding, especially post menstrual bleeding which may be present in up to 82% of these cases (Iannone et al 2019).
- Trial name
- NCT04579965
- Testing
- medical treatment of isthmocele
- Volunteers
- 50 people
- Sponsor
- Mansoura University Hospital
Quality of Life
Development of Isthmocele Symptom Severity and Quality of Life Scale
Isthmocele, also known as cesarean scar defect (CSD), is the disruption of the integrity of the myometrium in the cesarean section incision and the indentation of the opening in the myometrium towards the visceral peritoneum.
- Trial name
- NCT06562231
- Testing
- quality of life scale
- Where
- Turkey (Türkiye)
- Volunteers
- 330 people
- Sponsor
- Hilal Yuvacı
Uterine Scar
Difference Between Monofilament Versus Multifilament Suture Material in Isthmocele Formation
This thesis conducts the effect of using different suture materials on the development of uterine scar niche after cesarean section.
- Trial name
- NCT06741371
- Testing
- Monocryl
- Where
- Egypt
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Uterus; Scar
Isthmocele Development Due to Primary Cesarean Section at The Latent or Active Phase
The importance of isthmocele development due to primary cesarean section at the latent or active phase of labour
- Trial name
- Isthmocele (NCT04891042)
- Where
- Turkey (Türkiye)
- Volunteers
- 320 people
- Sponsor
- Zeynep Kamil Maternity and Pediatric Research and Training Hospital
Cesarean Section Complications, Cesarean Wound Disruption
Cesarean Scar Defect Formation After First Cesarean Section.
This study is a prospective observational study which will monitor how cesarean section in the first pregnancy will develop a cesarean scar defect.
- Conditions
- Cesarean Section Complications, Cesarean Wound Disruption, Cesarean Wound; Dehiscence
- Trial name
- NCT03966001
- Testing
- Transvaginal sonography at six months after cesarean section, Transvaginal sonography at twelve months after cesarean section
- Where
- Turkey (Türkiye)
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Uludag University
Cesarean Scar Defect (Isthmococele), Pelvic Pain
Single-Layer Versus Double-Layer Uterine Closure After Primary Cesarean Section
This study compares two surgical techniques for closing the uterus after cesarean section: single-layer versus double-layer closure.
- Conditions
- Cesarean Scar Defect (Isthmococele), Pelvic Pain, Spotting, Amenorrhea Secondary
- Trial name
- NCT07611331
- Testing
- Double-layer hysterorrhaphy at primary cesarean section, Single-layer hysterorrhaphy at primary cesarean section
- Where
- Tunisia
- Volunteers
- 384 people
- Sponsor
- Hédi Chaker Hospital
Isthmocele, Cesarean Section Complications
Effect of Baseball Suturing on Isthmocele and Residual Myometrial Thickness After Cesarean
Cesarean delivery rates in Turkey as well as all over the world are increasing. Recent data in Turkey shows that the value of cesarean delivery rate reached 53%. This worldwide increase causes new concerns.
- Trial name
- NCT04734366
- Testing
- Uterine closure with "Baseball" suture technique, Single Layer Continuous Locked
- Where
- Turkey (Türkiye)
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Tokat Gaziosmanpasa University