Clinical trials: Ivf
ARTIFICIAL INTELLIGENCE (AI) APPLICATIONS IN REPRODUCTIVE MEDICINE
ARTIFICIAL INTELLIGENCE IN REPRODUCTIVE MEDICINE
Many studies have been published investigating the use of AI as an unbiased, automated approach to embryo assessment. This review will summarize the recent AI advancements in the IVF field.
- Trial name
- AI in ART (NCT05699850)
- Testing
- ARTIFICIAL INTELLIGENCE (AI)
- Where
- 2 sites in Egypt
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Al Baraka Fertility Hospital
Infertility, in Vitro Fertilization (IVF)
Use of Artificial Intelligence for Clinical Assessment of Assisted Reproductive Techniques and IVF Outcomes
The use of machine learning techniques using an artificial intelligence tool is proposed to analyze clinical data to predict best possible IVF/ART outcomes.
- Conditions
- Infertility, in Vitro Fertilization (IVF), ART
- Trial name
- AI in ART (NCT04255615)
- Testing
- AI to analyze 3 D ultrasound
- Where
- United States
- Volunteers
- 4,000 people, healthy volunteers welcome
- Sponsor
- Weill Medical College of Cornell University
Infertility
Mitochondrial Activity of Cumulus Cells From the Cumulus-oocyte Complex and Oocyte Competence
The need for non-invasive biomarkers of oocyte competency has become urgent as women increasingly delay attempts at childbearing.
- Trial name
- NCT02793752
- Testing
- Age
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Main Line Fertility Center
Infertility
Psychosocial Determinants of Continuing or Discontinuing Infertility Treatment: A Psychological Analysis
The current study aims to explore and analyse the decision making process of couples in regards to continuing or discontinuing infertility treatment.
- Trial name
- NCT00974649
- Testing
- self-report questionnaire
- Where
- Belgium
- Volunteers
- 315 people, healthy volunteers welcome
- Sponsor
- University Hospital, Gasthuisberg
Infertility
Study of Gene Associations and Infertility
The purpose of this this study is to use DNA screening strategies to identify genes and localize genomic regions that are differentially expressed in patients with infertility to further understand the genetic basis for…
- Trial name
- NCT01223092
- Where
- United States
- Volunteers
- 5,000 people, healthy volunteers welcome
- Sponsor
- Reproductive Medicine Associates of New Jersey
Efficacy of DHEA, Pregnancy Rate
Administration of DHEA in Patients With Poor Response to Ovarian Stimulation for IVF
Poor responders to ovarian stimulation represents one of the most frustrating problems in reproductive medicine. The investigators hypothesize that ovarian response of those patients could improve by treating these patients with…
- Conditions
- Efficacy of DHEA, Pregnancy Rate, Diminished Ovarian Reserve, Changes in AMH
- Trial name
- DHEA (NCT02099916)
- Testing
- gonadotropins plus DHEA, Gonadotropins
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Athens
Use of GnRH Agonist Alone for Luteal Phase Support in Fresh IVF Cycles
GnRH Agonist for Luteal Phase Support.
Objective To assess the the efficacy of luteal support with GnRH agonist in patients undergoing IVF in antagonist-based hcg triggered cycles compared with standard luteal support with progesterone.
- Trial name
- NCT05484193
- Testing
- GnRH agonist, Progesterone
- Where
- Israel
- Volunteers
- 150 people, healthy volunteers welcome
- Sponsor
- Shaare Zedek Medical Center
IVF
Serum Progesterone on the Day of Thawed Embryo Transfer and Pregnancy Rate After an Artificial Endometrial Preparation
To determine if different serum Progesterone levels on FET day are associated with different clinical pregnancy rates (CPR), and if increasing dosage of vaginal Progesterone in cases of lower serum Progesterone level on FET day…
- Trial name
- NCT04278508
- Testing
- Progesterone
- Where
- Israel
- Volunteers
- 38 people, healthy volunteers welcome
- Sponsor
- Hillel Yaffe Medical Center
Infertility, IVF
The Importance of Embryo Transfer Day Progesterone Value in Natural Cycle Frozen Embryo Transfers and the Evaluation of the Effect of Rescue Therapy on Pregnancy Outcomes in Patients With Low Progesterone Levels
Thanks to recent advances in clinical practice and laboratory, embryo cryopreservation has become the first-line procedure in assisted reproductive technology.
- Conditions
- Infertility, IVF, Progesterone
- Trial name
- NCT05481684
- Testing
- Normal Progesterone group, Low Progesterone group
- Where
- 3 sites in Turkey (Türkiye)
- Volunteers
- 126 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Pregnancy Rates
Different Strategies in Frozen IVF/ICSI Cycles
In the absence of robust contemporary data, investigators decided to perform a multicenter cohort study of various IVF centers, to compare the different modalities used for pregnancy rates following frozen-thawed embryo transfer…
- Trial name
- NCT03965949
- Testing
- Hormone Replacement cycle 1, Hormone Replacement cycle 2
- Where
- Greece
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- National and Kapodistrian University of Athens
Infertility
Frozen Embryo Donation Study
The purpose of this study is to improve patient understanding of and interest in donating frozen embryos resulting from in vitro fertilization (IVF) to others undergoing infertility treatment.
- Trial name
- FREDS (NCT01883934)
- Testing
- Enhanced clinic-based support/counseling, Control
- Where
- United States
- Volunteers
- 3,568 people, healthy volunteers welcome
- Sponsor
- Boston IVF
Invitro Fertilization, Diminished Ovarian Reserve
Effect of Follicular Flushing in Patients With Mono-follicular Growth Undergoing In Vitro Fertilization
Retrieval of an oocyte from a follicle relies on the release of the cumulus-oocyte-complex (COC) from the follicular wall into the lumen, thereby allowing aspiration by a needle.
- Conditions
- Invitro Fertilization, Diminished Ovarian Reserve, Oocyte
- Trial name
- NCT03831542
- Testing
- direct follicular aspiration, follicular flushing
- Where
- Turkey (Türkiye)
- Volunteers
- 71 people, healthy volunteers welcome
- Sponsor
- Centrum Clinic IVF Center
Fertilization in Vitro
The Comparison of Granulosa Cell Apoptosis Rates With or Without Luteinizing Hormone Administration in Poor Responders.
In Zeynep Kamil Women and Children's Education and Research Hospital which is a tertiary referral hospital, the investigators perform microdose flare-up gonadotropin-releasing hormone (GNRH) analogue or GNRH antagonist protocol…
- Trial name
- NCT03527823
- Where
- Turkey (Türkiye)
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Sebnem Alanya Tosun
Fertility Disorders, Assisted Reproductive Technology
The Clinical Cohort Study of Reproductive Health
The study will conduct a multicenter prospective clinical cohort study to collect comprehensive health information and essential specimens from pre-pregnancy to postpartum offspring development.
- Conditions
- Fertility Disorders, Assisted Reproductive Technology, Offspring Health
- Trial name
- NCT05164029
- Testing
- Completion questionnaires/providing biological samples
- Volunteers
- 3,000 people, healthy volunteers welcome
- Sponsor
- Women's Hospital School Of Medicine Zhejiang University
Patient Education
Preimplantation Genetic Testing for Aneuploidy Counseling
Purpose: To evaluate preimplantation genetic testing counseling interventions on patients undergoing in vitro fertilization treatment.
- Trial name
- PGT-A (NCT06018454)
- Testing
- Handout on PGT-A, Handout on PGT-A and genetic counseling
- Where
- United States
- Volunteers
- 213 people, healthy volunteers welcome
- Sponsor
- Eyup Hakan Duran
Polycystic Ovary Syndrome, Ovarian Hyperstimulation Syndrome
In Vitro Maturation of Immature Oocytes
The aim of this study is to aspirate immature oocytes from antral follicles and mature the oocytes in vitro. These mature oocytes will serve for fertilization and the creation of embryos which will be replace in the uterus as…
- Trial name
- NCT00480337
- Testing
- In Vitro Maturation of immature oocytes
- Where
- Israel
- Volunteers
- healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Infertility
LH Hormone Pulsation in the Luteal Phase in GnRH Antagonist IVF Cycles Triggered by GnRH Agonist for Final Oocyte Maturation
Monitoring the LH pulsatility during the Luteal phase in GnRH antagonist IVF cycles triggered by GnRH agonist for final oocyte maturation.
- Trial name
- NCT02449642
- Where
- Israel
- Volunteers
- 10 people, healthy volunteers welcome
- Sponsor
- Rambam Health Care Campus
Reproductive Health, Time to Pregnancy
Reproductive Health of Couples of Childbearing Age: a Community Based Prospective Cohort Study
This community based prospective cohort study was established to investigate the fecundability of couples of childbearing age. Data are collected regarding age, body mass index, education, menstrual regularity as well as…
- Conditions
- Reproductive Health, Time to Pregnancy, Infertility, Risk Factor
- Trial name
- ReH-CP (NCT04068428)
- Where
- 4 sites in China
- Volunteers
- 2,313 people, healthy volunteers welcome
- Sponsor
- Guangzhou Women and Children's Medical Center
Neuro Developmental Delay
Heart Rate Variability in Children Conceived Via Assisted Reproductive Technologies
This is a proof of principle study that investigates heart rate variability differences in fetal and neonatal life in a longitudinal study design and compares two subject groups, offspring conceived using in-vitro fertilization…
- Trial name
- HRV ART (NCT00993369)
- Testing
- Holter monitor
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Utah
Infertility
The Impact of Distress on the IVF Outcome
Stress is a primary reason why in vitro fertilization (IVF) patients drop out of treatment, and it may have a detrimental impact on pregnancy rates, yet there is minimal published research on the efficacy of structured…
- Trial name
- NCT01103973
- Testing
- Mind/Body Program, Control
- Where
- United States
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- Boston IVF