Clinical trials: Ivf
Fertilization
Lipidic Differences of Sperm Between Normal and Low Fertilization Patients
Although in vitro fertilization (IVF) involve the use of semen samples, there is little scientific methodology applied when selecting sperm.
- Trial name
- NCT04537481
- Testing
- Lipid extraction
- Where
- China
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Tang-Du Hospital
Fertility Agents, Female
hCG Supplementation in Frozen-Thawed Embryo Transfer Cycle
The implantation rate after frozen-thawed embryo transfer cycles depends mostly on the receptivity of the endometrium and the embryo quality.The effects of human chorionic gonadotropins (hCG) on the endometrium have been…
- Trial name
- NCT00398229
- Testing
- s.c. human chorionic gonadotropin (Ovitrelle)
- Where
- Israel
- Volunteers
- 300 people
- Sponsor
- Hadassah Medical Organization
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Progestin-primed Ovarian Stimulation Protocol Versus GnRH Antagonist Protocol in Polycystic Ovary Syndrome Patients Undergoing IVF/ICSI Cycles
The purpose of this trial is to compare the efficacy and safety of the PPOS protocol to the GnRH antagonist protocol in patients with PCOS who are undergoing IVF/ICSI cycles.
- Trial name
- NCT05112692
- Testing
- Dydrogesterone Tablets, cetrorelix 0.25mg, human menopausal gonadotropin
- Volunteers
- 200 people
- Sponsor
- Mansoura University
Infertility
Effect of Ultrasound Guided Embryo Transfer on Pregnancy Rates
To assess the effect of transabdominal ultrasound guided embryo transfer on the pregnancy rates versus clinical touch technique
- Trial name
- ET (NCT01810601)
- Testing
- GnRh, HMG, HCG, Progesterone
- Where
- Egypt
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- Ain Shams Maternity Hospital
Vitamin D Deficiency
Follicular Fluid, Bioavailable Vitamin D and Embryo Quality Markers
To determine the correlation between bioavailable Vitamin D values and euploid status of the embryos in larger size follicles from UAE women undergoing in vitro fertilization procedures.
- Trial name
- NCT03073720
- Where
- United Arab Emirates
- Volunteers
- 43 people, healthy volunteers welcome
- Sponsor
- ART Fertility Clinics LLC
Infertility, Female
Melatonin Study Between Diminished and Normal Responder in IVF
Poor sleep quality may lead to increase in oxidative stress and free radicals which in turn may decrease the reproductive function.
- Trial name
- NCT03117725
- Testing
- Melatonin adminstration
- Where
- South Korea
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Bundang CHA Hospital
Infertility, Decreased Ovarian Reserve
A Trial of Dehydroepiandrosterone (DHEA) Treatment for in Vitro Fertilization (IVF)
Our long term goal is to elucidate the role of DHEA on follicular dynamics in the human ovary and to better understand the interaction of DHEA supplementation with other treatments for ovulation induction, especially among older…
- Trial name
- NCT00419913
- Testing
- Dehydroepiandrosterone
- Where
- 2 sites in United States, Austria
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Center for Human Reproduction
Infertility
The Valve of Hyaluronic Binding Selection (PICSI) in Improving IVF Outcome
The investigators would like to assess whether selecting mature sperm using PICSI (selecting for sperm that bind hyaluronan) can optimize the IVF outcome of ICSI . Aim 1.
- Trial name
- NCT01916213
- Testing
- PICSI
- Where
- United States
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Infertility
Gonadotropin-releasing Hormone (GnRH) Antagonist During 3 Days
In this prospective study, the investigators would like to show whether ovarian stimulation with pretreatment of a GnRH antagonist during 3 consecutive days at initiation of the cycle, is possible.
- Trial name
- NCT01093443
- Testing
- ovarian stimulation
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- Universitair Ziekenhuis Brussel
IVF Outcomes
HELIOS Advanced: Human Oocyte Illumination to Enhance Development
Oocytes need a lot of energy to complete meiosis and fertilize successfully. As women get older, the "power plants" of the cells (called mitochondria) don't work as well.
- Trial name
- HELIOS-A (NCT07425080)
- Testing
- Photobiomodulation
- Where
- United States
- Volunteers
- 270 people, healthy volunteers welcome
- Sponsor
- Columbia University
Activation of Primordial Follicles
Ovarian Needle Puncture for Follicle Activation in IVF Patients With Diminished Ovarian Reserve
Premature ovarian insufficiency (POI), is cessation of ovarian function characterized by hypergonadotropic amenorrhea and hypoestrogenic syndrome before 40 years of age.
- Trial name
- NCT04608695
- Testing
- Ovarian puncture
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people
- Sponsor
- Hacettepe University
Infertility
Three Small Doses of HCG Versus Booster Dose of HCG on Ovum Pickup Day
To salvage the luteal phase and improve pregnancy rate in antagonist IVF/ICSI cycles triggered with GnRH agonist. Two strategies are compared supplementing the luteal phase with three small doses (500 IU) of HCG and giving a…
- Trial name
- NCT02397551
- Testing
- IVF/ICSI, Human Chorionic Gonadotropin
- Where
- 3 sites in Egypt
- Volunteers
- 200 people
- Sponsor
- Cairo University
Infertility
Human Chorionic Gonadotropin (hCG) Test: A Novel Method to Evaluate the Ovarian Reserve
In an era of delayed fertility plans, there is an increasing need for a reliable method to predict ovarian reserve and responsiveness.
- Trial name
- NCT00646568
- Testing
- s.c. human chorionic gonadotropin (Pregnyl)
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- Hadassah Medical Organization
Infertility Assisted Reproductive Technology
fertiShare Evaluation
Sharing bad news (SBN) is a daily challenge for fertility staff and patients. Bad news happens at all stages of fertility care and includes e.g., diagnosing infertility, reporting unexpected, repeated, or definitive treatment…
- Trial name
- NCT06587360
- Testing
- fertiShare intervention - sharing bad news eLearning course, fertiShare control - basic communication skills eLearning course
- Where
- 5 sites in United Kingdom
- Volunteers
- 420 people, healthy volunteers welcome
- Sponsor
- Cardiff University
Repeated Implantation Failure
Atosiban Improves Implantation and Pregnancy Rates in Patients With Repeated Implantation Failure
Atosiban, administered at embryo transfer, can improve the implantation rate and the clinical pregnancy rate in patients with repeated implantation failure undergoing IVF-ET (in-vitro fertilization and embryo transfer).
- Trial name
- NCT01493440
- Testing
- atosiban
- Where
- Vietnam
- Volunteers
- 71 people
- Sponsor
- An Sinh Hospital
Reduced Sperm Motility, IVF
Sperm Selection and Embryo Development: Comparison of the Density Gradient Centrifugation and Microfluidic Chip Sperm Preparation Methods Sperm Selection and Embryo Development: Comparison of the Density Gradient Centrifugation and Microfluidic Chip Sperm Preparation Methods
Purpose: To compare the effects of the density gradient centrifugation and microfluidic chip sperm preparation methods on embryo development in a study population with astheno-teratozoospermia.
- Conditions
- Reduced Sperm Motility, IVF, ICSI, Astheno Teratozoospermia
- Trial name
- NCT04962074
- Testing
- Microfluidic sperm sorting chip, Density gradient
- Where
- Turkey (Türkiye)
- Volunteers
- 22 people
- Sponsor
- Maltepe University
Adenomyosis
Adenomyosis and ART
The goal of this clinical trial is to: Prospectively investigate the association of Adenomyosis with fertility outcomes in relation to COH protocols for ART (long or ultra- long protocol) with a preventive high-dose…
- Trial name
- ADENOFERT (NCT05937490)
- Testing
- Enantone, Dienogest 2 MG (milligram), long GnRH agonist or flexible GnRH antagonist protocol.
- Where
- Italy
- Volunteers
- 500 people, healthy volunteers welcome
- Sponsor
- Azienda Ospedaliero-Universitaria di Modena
Fertilization, Fertilization in Vitro
BEst Size for Ovulation Triggering in Poseidon 4 Patients (BEST 4 Study)
This observational clinical study aims to determine the optimal timing of ovulation triggering in women aged 35 and above with poor ovarian reserve.
- Trial name
- BEST (NCT06433518)
- Testing
- Ovulation Trigger Timing Based on Leading Follicle Size in POSEIDON Group 4 IVF Patients
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people
- Sponsor
- Centrum Clinic IVF Center
Infertility
Comparison of Global, G-TL, & Cornell Media
This is a prospective, randomized clinical trial to compare the Global commercial single step media to 1) G-TL (Vitrolife), 2) Weill Cornell's single step and sequential steps media, which all support human embryo development in…
- Trial name
- NCT03687697
- Testing
- Global vs. G-TL vs Cornell's C3 vs Cornell's C1/C2 media
- Where
- United States
- Sponsor
- Weill Medical College of Cornell University
Infertility
Impact of Meditation and Reiki on Assisted Reproduction Techniques Outcomes
Infertility is estimated to affect 15% of reproductive age couples worldwide and is defined as the inability to conceive after 12 months of unprotected sex for women under 35 or 6 months for women over 35 and is associated with…
- Trial name
- NCT04058262
- Testing
- Meditation presential, Reiki, Meditation (app)
- Where
- Brazil
- Volunteers
- 80 people
- Sponsor
- Federal University of Minas Gerais
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