Clinical trials: Ivf
In Vitro Fertilization, Poor Ovarian Response
Impact of Melatonin on IVF/ICSI Outcomes in Prospective Poor Responders
The purpose of this study is to investigate the impact of melatonin administration on in vitro fertilization (IVF/ICSI) outcomes namely the total number and quality of the oocytes and embryos in the prospective poor responders.
- Trial name
- NCT02993588
- Testing
- Melatonin
- Where
- 2 sites in Egypt
- Volunteers
- 100 people
- Sponsor
- Assiut University
Brugada Syndrome, Long QT Syndrome 3
Worm Study: Modifier Genes in Sudden Cardiac Death
Quest for modifier genes associated with ventricular arrhythmias in presence of a cardiac sodium channel gene (SCN5A-delPhe1617) mutation.
- Trial name
- NCT02014961
- Testing
- Dermal biopsy, Gastro-intestinal questionnaire, Whole-exome sequencing
- Where
- Netherlands
- Volunteers
- 223 people, healthy volunteers welcome
- Sponsor
- Maastricht University Medical Center
Infertility, Aneuploidy
Noninvasive Chromosomal Screening for Embryo Selection Trial
To determine the diagnostic accuracy of non-invasive preimplantation genetic testing for aneuploidy (NI-PGT-A) for embryo selection.
- Trial name
- NICEST (NCT04732013)
- Testing
- No clinical intervention is planned; study is observational
- Where
- Canada
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Olive Fertility Centre
PCOS (Polycystic Ovary Syndrome) of Bilateral Ovaries
Effect of Hyperandrogenism on IVF Outcomes in PCOS Patients
Ovulatory dysfunction affects 18 to 25% of infertile women, the most common identifiable condition is polycystic ovarian syndrome (PCOS).
- Trial name
- HIP (NCT05555680)
- Testing
- Ferriman-Gallwey Score
- Where
- Canada
- Volunteers
- 32 people
- Sponsor
- Clinique Ovo
Embryo Transfer, Luteal Support
Modified Luteal Support for Frozen-Thawed Embryo Transfer - A Prospective Study
This study evaluates the outcomes of frozen-thawed embryo transfer (FET) success rate with modified luteal support - addition of a single injection of HCG and GnRH-agonist, on day of ET and 4 days later, respectively vs.
- Trial name
- NCT02825290
- Testing
- Choriogonadotropin alfa, Triptorelin acetate
- Where
- Israel
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Polycystic Ovary Syndrome
Impact of Metformin on In Vitro Fertilization Outcomes in Overweight and Obese PCOS Women
RCT to investigate whether metformin co-treatment would improve IVF outcomes in overweight and obese women with PCOS.
- Trial name
- NCT02910817
- Testing
- Metformin
- Where
- Egypt
- Volunteers
- 102 people
- Sponsor
- Assiut University
Infertility
AMH and Dosing Regimens for Initial IVF Stimulation Protocols
This is a research study on a hormone in women called anti-mullerian hormone (AMH) an indicator of the amount of egg reserve in the ovaries. The research involves a blood draw to determine the AMH level.
- Trial name
- NCT03098199
- Testing
- 300IU Gonal-F, 150IU Menopur, 225IU Gonal-F
- Volunteers
- 78 people, healthy volunteers welcome
- Sponsor
- Reproductive Specialists of New York
Infertility, Female, Abortion, Habitual
Effects of PGS in Infertile Female Patients With RPL
Recurrent pregnancy loss (RPL) is a multifactorial disorder which affects about 1% of all couples and challenges both patients and clinicians technically and emotionally.
- Trial name
- NCT02223221
- Testing
- IVF/ICSI, PGS, Without PGS
- Where
- China
- Volunteers
- 189 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Infertility
Endometrial Sampling (Pipelle)in IVF Patients
A prospective cross-over randomized study aimed to test the hypothesis that local injury of the endometrium increases the implantation rate in the successive cycle.
- Trial name
- NCT00411021
- Testing
- Pipelle (Endometrial Sampling)
- Where
- Israel
- Volunteers
- 70 people, healthy volunteers welcome
- Sponsor
- Sheba Medical Center
Recurrent Implantation Failure, Infertility (IVF Patients)
Endometrial Immune Profile in Recurrent Implantation Failure
The goal of this observational study is to learn whether differences in the immune cells of the womb lining (endometrium) help explain why some women do not become pregnant despite several IVF attempts using good-quality embryos…
- Trial name
- NCT07848399
- Where
- United Kingdom
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- King's College London
Pulmonary Embolism, Venous Thromboembolism
Risk of Pulmonary and Venous Thromboembolism in Pregnancies After in Vitro Fertilization
Occurrence of venous thromboembolism during in Vitro Fertilization (IVF) pregnancies has been reported in numerous case reports and in two small consecutive series.
- Trial name
- NCT01524393
- Where
- Sweden
- Volunteers
- 140,458 people
- Sponsor
- Danderyd Hospital
Endometriosis, Infertility
GnRH-a and Pregnancy Rate in In Vitro Fertilization (IVF) Cycles.
The investigators attempted to establish a rationale for the Gonadotropin Releasing Hormone-agonist (GnRH-a) administration, post-laparoscopically, in women with mild endometriosis (until stage II, according to AFS) who underwent…
- Trial name
- NCT01269125
- Testing
- Leuprolide, IVF
- Where
- Greece
- Volunteers
- 180 people
- Sponsor
- University of Ioannina
Infertility, IVF
Priority to Cryopreservation Strategy (PCS) in IVF-ICSI Cycles
This multicentre randomized controlled trial will be done to evaluate a new strategy in IVF-ICSI practice that gives that priority to freeze for the embryos and goes to fresh embryo transfer only if at least one set of same…
- Conditions
- Infertility, IVF, ICSI, Cryopreservation
- Trial name
- PCS (NCT03913208)
- Testing
- Priority to freeze, Fresh embryo transfer
- Where
- Egypt
- Volunteers
- 1,000 people
- Sponsor
- Tanta University
Infertility, IVF
Immediate Versus Postponed Single Blastocyst Transfer in mNC-FET
The purpose of this randomized controlled trial is to investigate if immediate single blastocyst transfer (in the first menstrual cycle following oocyte retrieval) is non-inferior to standard postponed single blastocyst transfer…
- Trial name
- NCT04748874
- Testing
- Immediate mNC-FET
- Where
- Denmark
- Volunteers
- 464 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Infertility, Female, Ovarian Stimulation
Double Ovarian Stimulation as Accumulation Strategy for Older Infertile Patients With Suboptimal Ovarian Response
Patients with infertility of the older age group of 37-42 years - a large cohort of patients of reproductive medicine. Two possible causes reduce their probability of pregnancy - an increasing age and a decrease of the ovarian…
- Conditions
- Infertility, Female, Ovarian Stimulation, In Vitro Fertilisation
- Trial name
- NCT03400722
- Testing
- Pergoveris, Clomiphene
- Where
- Russia
- Volunteers
- 120 people
- Sponsor
- Nova Clinic, Russia
Effect on Implantation and Pregnancy Rates
Effect of Seminal Plasma Insemination on Pregnancy Rates After IVF-ET
Seminal plasma insemination into the vaginal vault of patients undergoing IVF-ET increases uterine receptivity.
- Trial name
- NCT01809366
- Testing
- seminal plasma insemination
- Where
- Israel
- Volunteers
- 200 people
- Sponsor
- Assaf-Harofeh Medical Center
Pregnancy
Clinical Study on the Effect of IVF-ET on Mother-to-child Transmission of Hepatitis B Virus
This study is intended to retrospectively collect HBV-infected pregnant women and non-HBV-infected pregnant women who have been born in IVF in the investigators' hospital, collect pregnant women's data during pregnancy, newborn…
- Trial name
- NCT03932851
- Testing
- IVF-ET
- Where
- China
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Beijing Ditan Hospital
Subfertility, Infertility
Hysteroscopy Before in Vitro Fertilization - Does it Improve the Outcome?
By randomizing sub-fertile women to either control or office-hysteroscopy in the circle prior to IVF or ICSI (intracytoplasmatic sperm injection ) treatment, we aim to enlighten whether hysteroscopy with endometrial biopsy…
- Trial name
- NCT01743391
- Testing
- Office-hysteroscopy with biopsy
- Where
- Denmark
- Volunteers
- 220 people, healthy volunteers welcome
- Sponsor
- Hvidovre University Hospital
Anxiety, Infertility, Female
Stress and Fertility: How to Lower Stress When Trying to Conceive
Psychological stress and its sources differ among the population and can be reduced in various ways. The practice of yoga has been shown to be an effective stress reducing agent.
- Trial name
- NCT03031990
- Testing
- In-person yoga for fertility group, Online yoga for fertility group, In person discussion only group
- Where
- United States
- Volunteers
- 300 people
- Sponsor
- Fertility Centers of Illinois
Infertility
GnRH Agonist Administration in the Luteal Phase of ICSI-ET Cycles
A single dose GnRH agonist administration in the luteal phase of assisted reproduction cycles was reported to increase pregnancy and birth rates. This study was done to evaluate the reproducibility of previous findings.
- Trial name
- NCT00516490
- Testing
- triptorelin acetate, Na Cl %0.9
- Where
- Turkey (Türkiye)
- Volunteers
- 570 people
- Sponsor
- V.K.V. American Hospital, Istanbul
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