Clinical trials: Ivf
Poor Ovarian Response
Novel Therapy for Poor Responders Management
Unfortunately for some infertile women, gonadotrophin administration results in a desultory ovarian response. While this is commonly due to diminished ovarian reserve, as indicated by advanced age and/or elevated basal day 3 FSH…
- Trial name
- NCT04310293
- Testing
- Femara,Grotwth hormone,HMG
- Where
- Bahrain
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Al Baraka Fertility Hospital
Subfertility
Comparative Effect of Theipoental and Propofol in IVF Outcome
In this study the aim is to compare the effect of the type of anaesthetic drug used during oocyte retrieval on fertilization rates of oocytes retrieved after ovarian stimulation for in-vitro fertilization.
- Trial name
- NCT02377778
- Testing
- Propofol, Thiopental
- Where
- Greece
- Volunteers
- 180 people
- Sponsor
- Aristotle University Of Thessaloniki
Infertility, Female
Daytime Profile of Salivary Progesterone
The aim of this study is to perform a 12-hour profile of free saliva progesterone during the luteal phase after fresh and frozen embryo transfer.
- Trial name
- NCT03725904
- Testing
- Progesterone analysis in saliva
- Where
- Denmark
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Peter Humaidan
Infertility
Mild Versus Conventional Ovarian Stimulation for Poor Responders Undergoing In Vitro Fertilisation
The investigators will examine the balance between IVF success in terms of outcome parameters, using a mild ovarian stimulation protocol, opposing it to the conventional stimulation regimens in poor responders undergoing IVF.
- Trial name
- NCT01319708
- Testing
- mild ovarian stimulation, conventional ovarian stimulation
- Where
- Greece
- Volunteers
- 50 people
- Sponsor
- National and Kapodistrian University of Athens
Ovarian Stimulation, Reproductive Techniques, Assisted
The Effect of Dual Trigger for Final Oocyte Maturation on IVF/ICSI Outcomes in Patients With Suboptimal Ovarian Response
Recently, in patients with a suboptimal ovarian response, a study of the role of adding a single dose of GnRH agonist to a standard dose of hCG to initiate final oocyte maturation has also been studied. Griffin et al.
- Trial name
- NCT04549649
- Testing
- Dual triggering
- Where
- Iran
- Volunteers
- 52 people, healthy volunteers welcome
- Sponsor
- Royan Institute
Infertility, Infertility (IVF Patients)
Language Matters: Exploring the Impact of Language Concordance on Fertility Treatment Progression
Currently, patients presenting to the Fertility and Reproductive Medicine Center meet with an English-speaking provider and communicate through an interpreter, as none of the physicians speak Spanish.
- Conditions
- Infertility, Infertility (IVF Patients), Infertility Assisted Reproductive Technology, Ovulation Ind
- Trial name
- ImpaLa (NCT06636838)
- Testing
- Spanish-Speaking Provider
- Where
- United States
- Volunteers
- 70 people
- Sponsor
- Washington University School of Medicine
Infertility
Platelet-Rich Protein and the Endometrium
Platelet-rich plasma (PRP) may promote the endometrial growth and improve pregnancy outcome of patients with thin endometrium undergoing ART treatments.
- Trial name
- NCT02973555
- Testing
- PRP injection
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hadassah Medical Organization
Pregnancy, Fertility
Prognostic Value of PIF Detection in Embryo Culture Media Correlation With Pregnancy Outcome
PIF: biomarker of successful implantation To overcome the poor reproductive potential of embryos generated during in vitro fertilization cycles and the lack of markers enabling the identification of the most competent ones, it is…
- Trial name
- PIF-SET1 (NCT01803893)
- Where
- 5 sites in United States, France and 1 more
- Volunteers
- 500 people
- Sponsor
- BioIncept LLC
Infertility, Infertility, Female
Aftificial Inteligence in Assisted Reproductive Techniques to Assess Oocyte Quality and Embryo Ploidy
The assisted reproduction success rate is affected by several factors including the age of the women, oocyte quality and maturation state, as well as sperm quality.
- Conditions
- Infertility, Infertility, Female, Infertility, Male, Infertility Unexplained
- Trial name
- SMARTAI (NCT06539104)
- Testing
- arteficial inteligence evaluation of oocyte and embryo development
- Where
- 4 sites in Czechia
- Volunteers
- 1,000 people
- Sponsor
- Charles University, Czech Republic
Infertility, Pain
Acupuncture for Symptom Control During Assisted Reproductive Treatments Procedures
Rationale for conducting the experiment: Israel performed IVF treatments since 1980. Although ART (Advanced Reproductive Treatments) have evolved over the years implantation and pregnancy rates have not met the expectations yet.
- Trial name
- NCT02611726
- Testing
- Acupuncture
- Volunteers
- 400 people, healthy volunteers welcome
- Sponsor
- Bnai Zion Medical Center
Subfertility
RCT on the Effect of Endometrial Injury on Ongoing Pregnancy Rate in Subfertile Women Undergoing IVF
Implantation failure remains one of the major factors limiting success in IVF treatment. It was postulated that the local injury to endometrium induces secretions of cytokines and growth factors such as leukemia inhibitory…
- Trial name
- NCT01977976
- Testing
- Endometrial aspiration by pipelle
- Where
- Hong Kong
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- The University of Hong Kong
Infertility
Optimal Timing For Embryo Transfer For Low Responder Patients
Women undergoing in vitro fertilization (IVF) therapy, who are low responder and agree to enter the trial will be randomized to a study group, for whom embryo transfer will be done on the same day as oocyte aspiration and…
- Trial name
- NCT01040247
- Testing
- Embryo Transfer
- Where
- Israel
- Volunteers
- 20 people
- Sponsor
- HaEmek Medical Center, Israel
Infertility
CONSORT Randomized Controlled Trial in Assisted Reproductive Technology
The overall objective of this trial is to compare the ovarian response in assisted reproductive technology (ART) subjects administered GONAL f® according to the 'Consistency in recombinant follicle stimulating hormone [r-FSH]…
- Trial name
- NCT00829244
- Testing
- GONAL f® prefilled pen
- Where
- Switzerland
- Volunteers
- 200 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Immunomodulatory Drugs, Killer-cell Immunoglobulin-like Receptors (KIRs)
Effect of Immunomodulatory Treatment on IVF (in Vitro Fertilization) Outcomes in Patients With KIR AA Genotype
The aim of the study is to investigate the immune cause of recurrent implantation failure (RIF) and the role of immunomodulatory treatment in IVF (in vitro fertilization) patients that have a KIR AA genotype.
- Conditions
- Immunomodulatory Drugs, Killer-cell Immunoglobulin-like Receptors (KIRs), KIR Alleles (KIR AA)
- Trial name
- NCT06264206
- Testing
- Killer-cell immunoglobulin-like receptors (KIRs) testing
- Where
- Romania
- Volunteers
- 65 people, healthy volunteers welcome
- Sponsor
- Calla IVF Center
Infertility
In Vitro Fertilisation Versus Intracytoplasmic Sperm Injection in Patients Without Severe Male Factor Infertility
Over recent decades, the use of intracytoplasmic sperm injection (ICSI) has increased, even among patients without severe male factor infertility.
- Trial name
- INVICSI (NCT04128904)
- Testing
- IVF, ICSI
- Where
- 6 sites in Denmark
- Volunteers
- 824 people
- Sponsor
- Copenhagen University Hospital, Hvidovre
Infertility
The Effect of DHEA on Markers of Ovarian Reserve in Women With Diminished Ovarian Reserve
This prospective study evaluates the effect of DHEA supplementation on markers of ovarian reserve in women with diminished ovarian reserve.
- Trial name
- NCT01129830
- Testing
- dehydroepiandrosterone
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Virginia Center for Reproductive Medicine
Infertility, Female, AMH
AMHR2 Polymorphism in Blood and Granulosa Cells in Unexplained Infertility
There are various known parameters for assessing ovarian reserve, including ovarian volume, antral follicle count, follicle stimulating hormone (FSH) and Inhibin B at the beginning of the menstrual cycle, as well as…
- Conditions
- Infertility, Female, AMH, IVF
- Trial name
- NCT05592730
- Testing
- AMHR2 polymorphism in blood, AMHR2 polymorphism in granulosa cell
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Bezmialem Vakif University
Infertility
PooR Embryo Yield Cleavage Stage Versus blaStocyst Embryo Transfer (PILOT STUDY)
The purpose of this small-scale pilot study (10 patients) is to test the study protocol for an RCT comparing IVF outcomes between day 3 and day 5 embryo transfer in patients with five or fewer embryos in a fresh embryo transfer…
- Trial name
- PRECiSE (NCT03764865)
- Testing
- day 3 uterine transfer, day 5 uterine transfer
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- Beth Israel Deaconess Medical Center
In Vitro Fertilization
Psychiatric and Social Impacts of IVF
To asses psychiatric impacts of In vitro fertilization.
- Trial name
- NCT05881044
- Testing
- Psychiatric interview
- Volunteers
- 52 people
- Sponsor
- Assiut University
Assisted Reproductive Technology, Female Infertility
A Comparing Study Between SJ04 and Ovidrel® in Healthy Subjects
This is a single-centre, randomised, open-label, single-dose, two-cycle, double-crossover study to compare the pharmacokinetics of SJ04 and Ovidrel® in healthy female subjects.
- Trial name
- NCT06599528
- Testing
- T-R (Test-Reference drug), R-T (Reference-Test drug)
- Where
- China
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Suzhou Centergene Pharmaceuticals Co.,Ltd.
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