Clinical trials: Ivf
Infertility
Efficacy and Safety of Shen Que (RN8) Moxibustion in Unexpected POR
Moxibustion of Shen Que (RN8) can increase the number of embryos available for transfer, thus improving pregnancy outcomes in women of advanced reproductive age who experience unexpected poor ovarian response.
- Trial name
- NCT05653557
- Testing
- Shen Que Moxibustion
- Where
- China
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Shandong University of Traditional Chinese Medicine
Infertility, Female, In-Vitro Fertilization
DHEA Supplementation for Low Ovarian Response IVF Patients
Approximately 10% of all couples will be diagnosed as infertile. The most efficient infertility treatment is In-Vitro Fertilization (IVF).
- Trial name
- NCT00549081
- Testing
- DHEA
- Sponsor
- Shaare Zedek Medical Center
Infertility, Female, Pregnancy Related
Low TGF-β and Embryo Implantation in the Context of Assisted Reproductive Technology: Confirmation of a Biomarker Predictive of Success and Characterization of the Immune Microenvironment.
Infertility affects about one in seven couples in France. Beyond the medical and personal challenges, it has major societal implications.
- Trial name
- ImmuNoFertilit (NCT07859930)
- Where
- France
- Volunteers
- 100 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Infertility, Female
Study to Compare Efficacy and Safety of Primapur and Gonal-f in Women for Assisted Reproductive Treatment
The purpose of this study is to show equivalence with regard to the number of oocytes retrieved between follitropin alfa (pen-injectors) Primapur® and Gonal-f® in woman undergoing IVF/ICSI
- Trial name
- NCT03088137
- Testing
- Follitropin alfa (Gonal-f), Follitropin alfa (Primapur)
- Where
- 3 sites in Russia
- Volunteers
- 118 people
- Sponsor
- IVFarma LLC
Assisted Reproductive Techniques
Trends in Live Birth Rates Attributable to Assisted Reproductive Technology in British Columbia
Investigators will examine trends in ART use in BC specifically. The use of ART has drastically changed the management of infertility, with worldwide estimates exceeding 1.8 million ART cycles in 2010 alone.
- Trial name
- NCT04373239
- Testing
- Assisted Reproductive Technology
- Volunteers
- 1,000 people
- Sponsor
- University of British Columbia
Infertility
Failure of Implantation After Recurrent Embryo Transfers
We will investigate maternal and embryonic factors in women with recurrent implantation failure, undergoing IVF/ ICSI treatment.
- Trial name
- NCT00351481
- Where
- Netherlands
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
Acupuncture, Recurrent Implantation Failure
Effect of Acupuncture on the Clinical Outcome of IVF-ET in Patients With Recurrent Implantation Failure
In order to explore the effect of acupuncture on the clinical outcome of IVF-ET in patients with recurrent implantation failure, the patients divide into the experimental group or the control group.
- Trial name
- NCT04822207
- Testing
- acupuncture
- Where
- China
- Volunteers
- 310 people
- Sponsor
- ShangHai Ji Ai Genetics & IVF Institute
Endometritis; Chronic, Subfertility
The FLORA-project: in Search for the Microbial Cause of Chronic Endometritis and the Most Appropriate Treatment to Obtain a Successful Pregnancy IVF/ICSI
Chronic endometritis is an inflammatory condition of the endometrium. This inflammation can negatively affect fertility and pregnancy. The pathology is frequently (+-10%) observed in women with fertility problems.
- Trial name
- FLORA (NCT05337072)
- Testing
- Microbiome study
- Where
- Belgium
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility, In-vitro Fertilization
NuvaRing vs. Oral Contraceptive Pills (OCP) for In-Vitro Fertilization (IVF) Pre-treatment
The newly designed contraceptive ring, Nuvaring has a lower total steroid dose, and medications are delivered locally. It has been proven to be as safe and effective as the combined OCP in ovarian suppression and preventing…
- Trial name
- NCT01298128
- Testing
- NuvaRing, marvelon
- Volunteers
- 70 people
- Sponsor
- University of Toronto
Infertility, Female, First Trimester Spontaneous Abortion
Determination of Circulating Placental Biomarkers Levels to Predict the Pregnancy Outcome of First Trimester After IVF.
This study will assess the predictive potential of circulating placental biomarkers for spontaneous miscarriage within the following month in an IVF setting.
- Trial name
- NCT04387994
- Testing
- Blood samples collection
- Where
- Portugal
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Infertility
Low Dose hCG in the Late Follicular Phase
In this study,the investigators compared two protocols for controlled ovarian hyperstimulation in infertility patients requiring IVF. In the control group, the patient undergoes a standard antagonist protocol.
- Trial name
- NCT00750100
- Testing
- human chorionic gonadotropin, recombinant gonadotropins
- Where
- Belgium
- Volunteers
- 70 people
- Sponsor
- Universitair Ziekenhuis Brussel
Infertility
Transabdominal US-guided (UGET) vs. Modified Transvaginal US-guided (mTVET) Embryo Transfer in Human IVF
One thousand, six hundred forty-eight IVF patients undergoing ET with fresh embryos, randomized to receive mTVET (n=828) or UGET (n=820).
- Trial name
- NCT02526472
- Testing
- ET under transabdominal US guidance (UGET), ET after transvaginal US uterine measurement (mTVET)
- Where
- Italy
- Volunteers
- 1,648 people
- Sponsor
- University of Turin, Italy
Infertility
In Vitro Maturation With in Vitro Fertilization (IVF) Compared to Mild in Vitro Fertilization
Methods of infertility treatment may involve in vitro fertilization or IVF. Though effective, IVF is complex and expensive. Methods using no gonadotropin hormone stimulation of the ovaries are being compared to mild stimulation…
- Trial name
- IVM vs IVF (NCT00867763)
- Testing
- In vitro maturation and in vitro fertilization, Low doses of gonadotropin stimulation.
- Where
- 2 sites in United States
- Volunteers
- 1,440 people, healthy volunteers welcome
- Sponsor
- Batzofin Fertility Services
Infertility
Vitrification Versus Slow Cooling of Human Cleavage Stage Embryos
Human embryos can be preserved for later transfers by freezing. Traditionally the slow cooling method has been used. About 70% of the embryos remain fully intact after thawing.
- Trial name
- NCT00886431
- Testing
- embryo vitrification
- Where
- 2 sites in Belgium, Netherlands
- Volunteers
- 146 people, healthy volunteers welcome
- Sponsor
- UMC Utrecht
In Vitro Fertilisation (IVF) Treatment
Effect of Oxytocin Antagonist on Reduction of Uterine Contractions
The main purpose of this clinical research trial was to evaluate the effects of barusiban compared to placebo on uterine contractions on luteal phase uterine contractions in oocyte donors supplemented with progesterone.
- Trial name
- EFFORT (NCT01043120)
- Testing
- Barusiban
- Where
- 5 sites in Belgium, Czechia and 1 more
- Volunteers
- 99 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
Autoimmune Diseases
Research of Predictive Factors of in Vitro Fertilization (IVF) Outcome AI-IVF Study
Infertility is the failure to achieve a clinical pregnancy after 12 months or more of regular unprotected intercourse, while subfertility means a delay in achieving pregnancy.
- Trial name
- AI-IVF (NCT06872294)
- Where
- Italy
- Volunteers
- 200 people
- Sponsor
- Fondazione IRCCS Policlinico San Matteo di Pavia
Infertility
A Comparative Study of Sibling Oocytes: ICSI vs. the PICSI Sperm Selection Method
The aim of this research is to compare sibling oocytes using two sperm selection methods for choosing the best quality spermatozoa before they are injected into oocytes and the influence of each of these methods on embryo quality…
- Trial name
- NCT03240302
- Testing
- ICSI petri dish, PICSI petri dish
- Where
- Israel
- Volunteers
- 50 people
- Sponsor
- Hillel Yaffe Medical Center
Infertility
What Embryoselection for What Chance of Success ? EmbryoSelect Study
The aim of the research is to evaluate the results of the first in vitro fertilization (IVF) attempt according to the type of embryo culture.
- Trial name
- EmbryoSelect (NCT04484181)
- Testing
- Embryo culture in time lapse technology (TLT), Embryo culture in conventional incubator
- Where
- 2 sites in France
- Volunteers
- 500 people
- Sponsor
- University Hospital, Bordeaux
IVF
Pivotal Observational CHLOE Study
This pivotal study is an observational, prospective assessment, multi-center, databank based, clinical study aimed to evaluate the performance of CHLOE™ algorithm in prediction of blastocyst formation.
- Trial name
- NCT06111365
- Testing
- CHLOE
- Where
- 3 sites in United States
- Volunteers
- 59 people
- Sponsor
- Fairtility
Infertility (IVF Patients), Oocyte Retrieval
Impact of the Operator Performing Oocyte Retrieval on the Cumulative Live Birth Rate
This is a monocentric retrospective observational study. The study investigates the impact of the operator performing the oocyte retrieval on the cumulative live birth rate (CLBR).
- Trial name
- OPU-CLBR (NCT06933901)
- Testing
- Oocyte retrieval
- Volunteers
- 19,500 people, healthy volunteers welcome
- Sponsor
- Istituto Clinico Humanitas
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