Clinical trials: Ivf
Ovarian Reserve, SARS-CoV-2 Infection
Effect of Sars-cov-2 on Donor Oocyte Quality and Quantity, a Multicenter Retrospective Study.
Purpose: To determine the impact of SARS-CoV-2 infection and immunization on ovarian response to controlled ovarian stimulation (COS) and embryo development after in vitro fertilization (IVF) Methods: A retrospective multicentric…
- Conditions
- Ovarian Reserve, SARS-CoV-2 Infection, Blastocyst
- Trial name
- NCT05562479
- Testing
- Sars Cov 2 infection, Sars Cov 2 vaccination
- Where
- Colombia
- Volunteers
- 428 people, healthy volunteers welcome
- Sponsor
- Novafem
In Vitro Fertilization
Bed Rest or no Bed Rest?
A comparative study to determine whether bed rest after embryo transfer (ET) affects on IVF (In Vitro Fertilization)outcome. This study includes 240 patients undergoing IVF treatment with donated oocytes.
- Trial name
- NCT01343992
- Testing
- Bed rest, No bedrest
- Where
- Spain
- Volunteers
- 240 people, healthy volunteers welcome
- Sponsor
- Instituto Valenciano de Infertilidad, IVI VALENCIA
In Vitro Fertilization
EXpression PRofile Endometrium Samples Study
This is a Phase IV, pilot, open-label, national, multi-centric study planned to determine the gene expression profiles and histologic changes of the endometrial tissue before and after stimulation with Gonal-f®.
- Trial name
- EXPRESS (NCT01210144)
- Testing
- Gonal -f® [r-hFSH], Ovitrelle® [r-hCG alfa], Gonadotropin-releasing hormone (GnRH) Agonist
- Where
- France
- Volunteers
- 27 people
- Sponsor
- Merck KGaA, Darmstadt, Germany
Male Infertility, Unexplained Infertility
Impact of Sperm DNA Integrity on In Vitro Cycles
Sperm DNA integrity will be measured via the Toluidine Blue Assay (TBA) for patients undergoing In Vitro Fertilization (IVF); the study will determine correlations, if any, between IVF success and sperm DNA integrity.
- Conditions
- Male Infertility, Unexplained Infertility, Abortion, Habitual
- Trial name
- TBA on IVF (NCT01232465)
- Where
- United States
- Volunteers
- 420 people
- Sponsor
- Northwell Health
Reproductive Techniques, Assisted
Endometrial Volume and Sub-endometrial Vascularity as Predictors of In-vitro Fertilization Success
100 patients aged 21-40 years old, diagnosed as primary or secondary infertility These patients are then assigned to receive ICSI treatment (ovulation induction, .
- Trial name
- NCT02381821
- Testing
- 3 D ultrasound and Doppler examination, GnRH agonist
- Volunteers
- 82 people
- Sponsor
- Cairo University
Maternal Distress, Child Development
In Vitro Fertilization (IVF) and Prenatal Effects Independent of Genetics
This study examines how maternal stress during pregnancy affects infant brain and behavioral development, focusing on whether these effects are due to the prenatal environment or shared genes.
- Trial name
- NCT07296107
- Testing
- Prenatal maternal psychosocial and biological assessment protocol
- Where
- United States
- Volunteers
- 360 people, healthy volunteers welcome
- Sponsor
- Columbia University
Medically Assisted Procreation (MAP), Oocyte Retrieval
Monocentric Randomised Controlled Trial to Assess Whether Virtual Reality Reduces the Use of Hypnotic Agents During IVF/ICSI Oocyte Retrieval
Over the last few years, audiovisual distraction devices using animation, films and 3D immersion have been developed, with the aim to provide patients with a relaxing experience that disconnects them from the operating…
- Trial name
- REVAHPOVO (NCT07190729)
- Testing
- Propofol sedation + Audiovisual distraction, Propofol sedation
- Where
- France
- Volunteers
- 52 people
- Sponsor
- Groupe Hospitalier Diaconesses Croix Saint-Simon
Female Infertility
A Multicenter Study Comparing the Efficacy, Safety and Tolerability of Oral Dydrogesterone 30 mg Daily Versus Intravaginal Micronized Progesterone Capsules 600 mg Daily for Luteal Support in In-Vitro Fertilization
Female inability to conceive a child. The purpose of this randomized, two-arm and double blind, double dummy study is to demonstrate that the treatment of a daily dose of 3x10mg dydrogesterone orally is as effective and safe as…
- Trial name
- Lotus I (NCT01850030)
- Testing
- Dydrogesterone 30 mg, Micronized Progesterone 600 mg
- Where
- 40 sites in Austria, Belgium and 5 more
- Volunteers
- 1,070 people
- Sponsor
- Abbott
Infertility, Female
Parental Attitudes in Invitro Fertilization
The relationship between revelation of mode of conception and child behavior is not known
- Trial name
- NCT04126109
- Testing
- questionaire
- Where
- Egypt
- Volunteers
- 400 people
- Sponsor
- Aljazeera Hospital
IVF Cycle, Ovarian Stimulation
Efficacy and Safety of Medication Used to Stimulate Ovulation
Individuals undergoing In Vitro Fertilization must undergo controlled ovarian hyperstimulation (COH) to produce enough quality eggs for fertility treatment.
- Conditions
- IVF Cycle, Ovarian Stimulation, Egg Retrieval, Pregnancy
- Trial name
- NCT02715336
- Testing
- Ovulation induction with hCG and Lupron (GnRH agonist)
- Where
- Canada
- Volunteers
- 666 people, healthy volunteers welcome
- Sponsor
- Create Fertility Center
Embryo Implantation, ART
The Impact of Endometrial Compaction on Assisted Reproductive Technology Outcome
Absence of endometrial compaction on the day of ET has adverse effects on success of ART outcome.
- Trial name
- NCT04721522
- Testing
- blood sampling & ultrasound
- Where
- Egypt
- Volunteers
- 356 people
- Sponsor
- Zagazig University
Infertility
In Vitro Fertilization (IVF) and Acupuncture for Infertility
The aim of this investigation is to determine the value of combining acupuncture with infertility patients undergoing In Vitro Fertilization (IVF).
- Trial name
- NCT00736411
- Testing
- acupuncture, IVF
- Where
- United States
- Volunteers
- 320 people, healthy volunteers welcome
- Sponsor
- Pacific Fertility Center
Lifestyle Factors
Influence of Diet and Lifestyle Factors on the Results of the IVF
The purpose of this study is study the possible relationship between various lifestyle habits of men and women (age, body mass index, diet, exercise, alcohol, tobacco, coffee, etc..) and live birth rate after in vitro…
- Trial name
- NCT02072564
- Testing
- Questionnaire
- Where
- Spain
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Fundació Institut de Recerca de l'Hospital de la Santa Creu i Sant Pau
Embryo Implantation
Laser Acupuncture Before and After Embryo Transfer Improves IVF Outcomes
This study evaluated whether laser acupuncture at the time of embryo transfer (following in vitro fertilization) improves implantation rates.
- Trial name
- NCT02815371
- Testing
- Needle Acupuncture, Laser Acupuncture
- Where
- 2 sites in United States
- Volunteers
- 803 people
- Sponsor
- Reproductive Medicine Associates of New Jersey
Infertility, Female
Can Antioxidants Affect Pregnancy Rate in Patients With Expected Low Number of Egg Retrieval in IVF Cycles?
The aim of the study is to evaluate the effect of antioxidants on IVF outcome in infertile patients undergoing IVF who are expected to produce low number of eggs compared to a control group.
- Trial name
- NCT03085030
- Testing
- Antioxidant Formula
- Where
- Egypt
- Volunteers
- 593 people
- Sponsor
- Cairo University
Embryo Culture, Embryo Culture Media
Evaluation of an Undisturbed Embryo Culture System for Embryo Development in IVF/ICSI Cycles
This is a prospective, multicenter, randomized controlled clinical trial designed to evaluate whether a fully undisturbed closed embryo culture system can improve the developmental potential of embryos cultured in vitro and…
- Conditions
- Embryo Culture, Embryo Culture Media, Embryo Quality
- Trial name
- Embryos UECS (NCT07522281)
- Testing
- Gems FEM fertilization medium + Geri incubator+Gems one-step medium, Vitrolife fertilization medium+benchtop incubator + Vitrolife sequential culture media
- Volunteers
- 478 people, healthy volunteers welcome
- Sponsor
- Sun Yat-sen University
Obesity, Infertility
Multidisciplinary Treatment of Obesity Prior to in Vitro Fertilization: Impact on Global Reproductive Outcomes (PRO-FIV Study)
The aim of the present study is to evaluate the impact of a multidisciplinary treatment of obesity prior to IVF on global reproductive outcomes and maternofetal metabolic and cardiovascular risk factors.
- Trial name
- PRO-FIV (NCT03395067)
- Testing
- Intervention group
- Where
- Spain
- Volunteers
- 104 people
- Sponsor
- Hospital Clinic of Barcelona
in Vitro Fertilization
ICSI Using Pentoxifylline to Identify Viable Spermatozoa in Absolute Asthenozoospermia Patients
Absolute asthenozoospermia is a rare condition in men with an occurrence frequency of 1/5000 and greatly affects fertility product. Previous studies have shown that the ovum can be fertilized with live but immotile sperm.
- Trial name
- NCT05943353
- Testing
- Pentoxifylline
- Where
- Vietnam
- Volunteers
- 10 people
- Sponsor
- Mỹ Đức Hospital
Fertility
Multi-Center, Randomized, Open-Label, Parallel Group Study of a Vaginal Micronized Progesterone Tablet (Endometrin®) Compared to Crinone 8% Vaginal Gel in Female Patients Undergoing In-Vitro Fertilization (IVF)
This multicenter, randomized, open-label study will be performed in approximately 990 healthy females undergoing IVF. Each study center will follow their study center standard practice for IVF unless otherwise noted in this…
- Trial name
- NCT00296478
- Testing
- Endometrin, Crinone
- Volunteers
- 1,211 people, healthy volunteers welcome
- Sponsor
- Ferring Pharmaceuticals
IVF
Effect of Reducing the Oxygen Concentration From 5% to 2% on ICSI Outcome
To assess the effect of reducing the oxygen concentration from 5% to 2% on Intracytoplasmic sperm injection (ICSI) outcome.
- Trial name
- NCT05924048
- Testing
- Reducing the Oxygen Concentration From 5% to 2%
- Where
- Egypt
- Volunteers
- 196 people, healthy volunteers welcome
- Sponsor
- International Islamic Center for Population Studies and Research
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