Clinical trials: Ivf
Infertility
Physiotherapy in Assisted Reproductive Treatment
Research examines the effect of physiotherapy on treatment success by assisted reproductive technologies. It is based on a treatment of infertility by physiotherapeutic intervention after which the participants will undergo a…
- Trial name
- NCT04971824
- Testing
- Physiotherapeutic intervention
- Where
- Czechia
- Volunteers
- 42 people
- Sponsor
- Klaudia Fabičovic, PT
Infertile Women Undergoing IVF or ICSI
Postbiotic Intervention on Vaginal Microbiota
This study investigates the effects of postbiotic intervention on vaginal microbiota in infertile patients. Using a pre-post test design, we will enroll 15 women aged 30-45 years with at least two IVF failures.
- Trial name
- NCT07278024
- Testing
- postbiotics
- Where
- Taiwan
- Volunteers
- 15 people
- Sponsor
- Kaohsiung Veterans General Hospital.
Placenta; Implantation
Prospective Randomized Study to Evaluate the Effect of Embryonic Observation on the Gestation (PROdE)
In a conventional in vitro fertilization (IVF) cycle, daily microscopic observation of embryos outside the incubator to assess their morphology and establish a selection process is performed.
- Trial name
- PROdE (NCT02372279)
- Testing
- Embryo observation
- Where
- Spain
- Volunteers
- 193 people
- Sponsor
- Instituto Bernabeu
Bacterial Vaginoses, Infertility, Female
The Effect of Clindamycin and a Live Biotherapeutic on the Reproductive Outcomes of IVF Patients With Abnormal Vaginal Microbiota
Study question: Does antibiotic alone or in combination with live biotherapeutic treatment of an abnormal vaginal microbiota improve the reproductive outcomes of IVF couples? Study hypothesis: The investigator hypothesize that…
- Trial name
- NCT05166746
- Testing
- Clindamycin
- Where
- 4 sites in Denmark
- Volunteers
- 333 people
- Sponsor
- Peter Humaidan
Ovarian Function at Advanced Reproductive Age
Co Enzyme Q10 Improves IVF Outcome in With Advanced Reproductive Age
The goal of the investigators research is to explore energy production of the ovarian follicle in older reproductive age women at the time of oocyte retrieval.
- Trial name
- NCT01659788
- Testing
- Coenzyme Q10 concomitant treatment
- Where
- Israel
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Hadassah Medical Organization
In Vitro Fertilization, ICSI Intracytoplasmic Spermatozoid Injection
Luteal Phase Support With GnRH Agonist After GnRH Agonist Triggering in IVF/ICSI Cycles
The development of stimulation protocols for in vitro fertilisation (IVF) has led to a paradox. It has now been established that obtaining a large number of oocytes is a key to success, but that it is also a risk factor for…
- Trial name
- SOLOAGO (NCT06150703)
- Testing
- Ovulation induction with hCG + Luteal phase support with vaginal progesterone, Ovulation triggering by Triptorelin + Luteal phase support by Nafarelin
- Where
- France
- Volunteers
- 652 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
IVF
RIOTC: Reducing the Impact of Ovarian Stimulation. Novel Approaches to Luteal Support in IVF-Study 2
The goal of the randomised controlled study (RCT) is to identify novel strategies that can improve the luteal phase endocrinology after ovarian stimulation, with the aim of using less or no luteal support in IVF while making the…
- Trial name
- RIOTC (NCT04524026)
- Testing
- Letrozole 5 mg
- Where
- 2 sites in Denmark
- Volunteers
- 25 people
- Sponsor
- Nicholas Macklon
Low Responder
Oxidative Stress-related Gene Expression in Cumulus Cells Among Low Responders
In Vitro Fertilization is considered one of effective treatment for infertile couple. However, some women do not have adequate response to controlled ovarian hyperstimulation, resulting in low response which defined as less than…
- Trial name
- NCT03155438
- Testing
- Oxidative stress-related gene expression (RNA expression), oocyte competence biomarkers
- Where
- Thailand
- Volunteers
- 56 people, healthy volunteers welcome
- Sponsor
- Chulalongkorn University
Diminished Ovarian Reserve, Premature Ovarian Insufficiency
Autologous Platelet-rich Plasma (PRP) Infusion to Improve Outcomes in Women With Ovarian Insufficiency: a Pilot Study
The investigators propose a pilot study to determine if autologous platelet-rich plasma (PRP) improves ovarian reserves and In-vitro fertilisation (IVF) outcomes in women with diminished ovarian reserve / premature ovarian…
- Conditions
- Diminished Ovarian Reserve, Premature Ovarian Insufficiency, Fertility Issues, IVF
- Trial name
- NCT05385848
- Testing
- Autologous Platelet-rich Plasma (PRP) Injection
- Where
- Singapore
- Volunteers
- 30 people
- Sponsor
- KK Women's and Children's Hospital
Infertility, IVF
Health of Babies Born From IVF Versus IVM at 5 Years Old
The investigators conduct a long-term follow-up at five years on offspring born from our randomized controlled trial (RCT) to investigate whether or not there is any difference in developmental outcomes in children born after…
- Conditions
- Infertility, IVF, IVM, Development, Child
- Trial name
- FM-BABIES-5Y (NCT06369415)
- Testing
- Developmental score according to The Ages & Stages Questionnaires®, Third Edition - ASQ®-3 and behavioural screening according to Strength and Difficulties Questionnaires (SDQ's)
- Where
- Vietnam
- Volunteers
- 214 people
- Sponsor
- Mỹ Đức Hospital
Infertility (IVF Patients), Artificial Intelligence (AI)
AI-Driven Model Impact on Patient Engagement in Medically Assisted Reproduction
Infertility is a globally significant medical condition, profoundly impacting individuals and couples both emotionally and physically.
- Trial name
- NCT07087171
- Testing
- Artificial intelligence-Machine learning report with accurate personalized probabilities of having a live birth rate
- Where
- Portugal
- Volunteers
- 774 people
- Sponsor
- Instituto Valenciano de Infertilidade de Lisboa
Infertility
Comparison of the Accuracy and Reliability of AMH, FSH and AFC in Predicting Ovarian Response
Serum bio-markers have different prediction values for ovarian response during ovarian stimulation in-vitro fertilization
- Trial name
- AMH FSH AFC (NCT02173444)
- Testing
- Blood test
- Where
- Vietnam
- Volunteers
- 820 people
- Sponsor
- Vietnam National University
Infertility, Female, Depression
Educational and Supportive Care to Depressed Infertile Females
Infertility affects married adults, and In Vitro Fertilization (IVF) is an Assisted Reproductive Technology (ART) that can be treated. Women undergoing IVF are more likely to experience depression.
- Conditions
- Infertility, Female, Depression, IVF
- Trial name
- NCT06022640
- Testing
- Educational and supportive care
- Where
- Iraq
- Volunteers
- 150 people
- Sponsor
- Al-Rasheed University College
Fibroid Uterus, IVF
The Value of Myomectomy in Women With Intramural Myoma Before IVF.
Women with intramural myoma not reaching the endometrial cavity will be randomized to either open myomectomy or no intervention .
- Trial name
- NCT03904368
- Testing
- Open myomectomy, Gonadotropins, Human chorionic gonadotropin
- Where
- Egypt
- Volunteers
- 100 people
- Sponsor
- Cairo University
Women Infertility
Lipoic Acid Supplementation in IVF
Alpha-Lipoic Acid (ALA) is a natural molecule that can make a significant contribution to the success of embryo implantation phase, because it exerts, directly or indirectly, an immunomodulatory activity.
- Trial name
- NCT03023514
- Testing
- Oral Lipoic acid, Vaginal Progesterone
- Where
- Greece
- Volunteers
- 172 people
- Sponsor
- Lo.Li.Pharma s.r.l
Cesarean Section, ART
Cesarean Section Scar Niche: The Impact on ART Outcome
To evaluate the impact of the presence of cesarean section niche and its characteristics on the outcome of ART cycles.
- Trial name
- NCT05358678
- Testing
- cs niche group
- Where
- Egypt
- Volunteers
- 266 people
- Sponsor
- Rahem Fertility Center
Human Papilloma Virus, Infertility, Female
Impact of Human Papillomavirus Carriage on IVF/ICSI Results (HPV AMP)
The prevalence of the papilloma virus in the general population is 12%. This virus is known to impair male fertility but its impact on female infertility remains uncertain.
- Trial name
- HPV-AMP (NCT06550531)
- Where
- France
- Volunteers
- 618 people
- Sponsor
- University Hospital, Brest
Covid-19 Vaccination
The Effect of Covid-19 Vaccination in Patients Undergoing IVF
Since emerging in the last months of 2019, over 127 000 000 individuals have suffered severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2) infection, and the documented death toll from coronavirus disease 2019 (COVID-19)…
- Trial name
- Covid-19 (NCT05063942)
- Volunteers
- 712 people
- Sponsor
- Shanghai First Maternity and Infant Hospital
Assisted Reproductive Technology
Progesterone Supplementation on Women Having Low Progesterone Levels on Transfer Day
The main objective of this study is to compare clinical pregnancy rates between two groups of women who have progesterone levels below 10 ng/mL on the day of frozen embryo transfer: group 1 (vaginal micronized progesterone…
- Trial name
- NCT04897269
- Testing
- Progesterone supplementation
- Where
- Vietnam
- Volunteers
- 824 people, healthy volunteers welcome
- Sponsor
- Tu Du Hospital
Polygenic Score
Polygenic Embryo Selection
This study will evaluate whether IVF success rates after PRS-based embryo selection differ from those after morphology-based embryo selection, and whether polygenic disease risk correlates with embryo morphology.
- Trial name
- NCT07841769
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- Nucleus Genomics Inc.
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