Clinical trials: Jaw Diseases
Mandibular Dysfunction
Intramuscular Injections of Botulinum Toxin in Lateral Pterygoid Muscle in the Treatment of Temporomandibular Dysfunctions: Studying the Interest of MRI Guidance and Ultrasound Guidance
The main hypothesis is that a significant pain improve (measured with Visual Analogic Scale [VAS]) can be observed after injection of botulinum toxin A, meaning the success of the guidance device.
- Trial name
- MAUSBOT (NCT04900324)
- Testing
- MRI guidance, Ultrasound guidance
- Where
- France
- Volunteers
- 4 people
- Sponsor
- Centre Hospitalier Universitaire de Besancon
Tooth Extraction Status Nos, Cysts Dental
Intravenous Dexamethasone on Postoperative Pain and Complications in Jaw Surgery
This study aims to evaluate the effect of single-dose intravenous dexamethasone on postoperative pain and other complications in compacted tooth and cyst enucleation procedures performed under general anesthesia.
- Conditions
- Tooth Extraction Status Nos, Cysts Dental, General Anesthesia
- Trial name
- DXM-PAIN (NCT06787196)
- Testing
- Dexamethasone
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Selcuk University
Temporomandibular Joint Disorder
Biobehavioral Pain Management in TMD
TMD is a poorly understood chronic pain disorder that affects up to 15% of the adult population, notably impacting women, is linked to greater healthcare utilization, and associated with multiple pain-related co-morbidities.
- Trial name
- TMD (NCT01794624)
- Testing
- Cognitive Therapy for Catastrophizing, Behavioral Therapy for Sleep Continuity Disturbance
- Where
- 2 sites in United States
- Volunteers
- 300 people
- Sponsor
- Johns Hopkins University
Temporomandibular Joint Disorders, Myofascial Pain Syndromes
Post-Isometric Relaxation in Temporomandibular Disorders
This planned randomized, single-blind clinical trial will investigate the effects of adding the Post-Isometric Relaxation (PIR) technique to a standard postural exercise program in individuals with moderate to severe…
- Conditions
- Temporomandibular Joint Disorders, Myofascial Pain Syndromes, Mandibular Dysfunction
- Trial name
- PIR-TMD (NCT07130279)
- Testing
- Postural Exercises + Post-Isometric Relaxation (PIR) Technique, Postural Exercises
- Volunteers
- 40 people
- Sponsor
- Sanem ŞENER
Periapical Diseases, Bioceramic Sealers
Survival and Success of Two Different Filling Techniques
This randomized clinical study analysed the clinical use of a new bioceramic premixed CaSi-containing sealer in association with a warm carrier-based technique or a traditional epoxy resin based sealer.
- Conditions
- Periapical Diseases, Bioceramic Sealers, Survival Rate, Healing Rate
- Trial name
- ROOTCANAL (NCT06252337)
- Testing
- bioceramic sealer group
- Where
- Italy
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- University of Bologna
Sedation, Emergence Delirium
Nebulized Dexmedetomidine Combined With Ketamine Versus Nebulized Dexmedetomidine for Cleft Palate
To compare the efficacy of the pre-operative nebulization of a combination of dexmedetomidine and ketamine versus nebulization of dexmedetomidine alone for sedation and prevention of emergence delirium in children undergoing…
- Trial name
- NCT05821972
- Testing
- Nebulization of dexmedetomidine and ketamine, Nebulization of dexmedetomidine
- Where
- Egypt
- Volunteers
- 60 people
- Sponsor
- Assiut University
Temporomandibular Disorder
Clinical Evaluation of Botulinum Toxin a in the Management of Temporomandibular Myofascial Pain
This study is a randomized, double-blind, placebo-controlled clinical trial designed to evaluate the effectiveness of botulinum toxin type A (BoNT-A) in patients with temporomandibular myofascial pain who have not improved after…
- Trial name
- NCT07847541
- Testing
- Botulinum Toxin Type A (BoNT-A)
- Where
- Pakistan
- Volunteers
- 118 people
- Sponsor
- Riphah International University
Temporomandibular Disorder
Effect of Massage Therapy and Occlusal Splint Therapy on the Electromyographic Activity and Mandibular Range of Motion in Individuals With Temporomandibular Disorder
The objectives of this study were to investigate the effects of massage therapy and occlusal splint therapy in the electromyographic activity and mandibular range of motion (ROM) in individuals with temporomandibular disorder…
- Trial name
- NCT01874041
- Testing
- Massage, Occlusal splint
- Where
- Brazil
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- University of Nove de Julho
Temporomandibular Disorder
The New Serial Treatment of Temporomandibular Disorders
The purpose of this study is to look at temporomandibular joint (TMJ) pressure as a guideline to analyze the different treatments for temporomandibular disorder (TMD), and judge the feasibility of the adjust TMJ pressure…
- Trial name
- NCT00932594
- Testing
- Adjust the TMJ Pressure to Normal Value, Do not adjust the pressure of TMJ
- Where
- China
- Volunteers
- 4 people
- Sponsor
- Sun Yat-sen University
Mandibular Fractures
Bone Regeneration With Mesenchymal Stem Cells
Mandible fractures are a common cause of facial injury in adults. The autologous mesenchymal stem cell (AMSC) transplantation, is proposed as an alternative to the conventional graft treatment, improving bone neoformation.The…
- Trial name
- NCT02755922
- Testing
- Application of autologous mesenchymal stem cells
- Volunteers
- 20 people
- Sponsor
- Instituto Mexicano del Seguro Social
Osteoarthritis
Synvisc to Treat Osteoarthritis of the Temporomandibular Joint
This study will examine the effectiveness of injected hylan (Synvisc) for treating pain associated with osteoarthritis of the temporomandibular joint (jaw joint) and improving function of the joint.
- Trial name
- NCT00078351
- Testing
- High molecular weight hylan (Synvisc) injection
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- National Institute of Dental and Craniofacial Research (NIDCR)
Apical Periodontitis
Apical Periodontitis and Glycemic Control in Diabetic and Non-diabetic Egyptian Sub-population
This observational cross-sectional study aims to assess the prevalence of apical periodontitis in diabetic and non-diabetic adult Egyptian patients and to evaluate its association with glycemic control measured by glycated…
- Trial name
- NCT07856186
- Volunteers
- 88 people, healthy volunteers welcome
- Sponsor
- Cairo University
Cleft Palate
Improving Outcomes in Cleft Palate Surgery
This is a pilot study to determine if an audit and feedback intervention decreases complication rates after cleft palate surgery.
- Trial name
- NCT02583100
- Testing
- Intensive Feedback, Routine Feedback
- Where
- 6 sites in United States, Canada
- Volunteers
- 7 people
- Sponsor
- Children's Hospital Medical Center, Cincinnati
Atrophic Maxilla
Assessment of Bone Quality and Quantity for Three Dimensional Bone Augmentation for Maxilla Using Patient Specific Titanium Meshes Loaded With Bone Marrow Aspirate Mixed With Xenograft Versus Xenograft Mixed With Autografts Only: a Randomized Clinical Trial
Assessment of bone quality and quantity for three dimensional bone augmentation for maxilla using titanium meshes loaded with bone marrow aspirate mixed with xenograft versus xenograft mixed with autografts only
- Trial name
- NCT05400044
- Testing
- Three dimensional maxillary bone augmentation
- Where
- Egypt
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Cairo University
Disc Degenerative Disease, Spine Degeneration
Physiotherapy and Osteopathic Treatment for Pain in the Cervical and Lumbar Spine and Temporomandibular Joints
Study Summary: Effectiveness of Physiotherapy and Osteopathy in Treating Spinal and Temporomandibular Joint Pain About the Study and Its Objective This study is conducted by Artur Hołodniuk, MSc, a physiotherapist and academic…
- Conditions
- Disc Degenerative Disease, Spine Degeneration, Back Ache, Temporomandibular Disorder (TMD)
- Trial name
- NCT07830836
- Testing
- General Osteopathic Treatment, Visceral Therapy, Magnetic field therapy
- Where
- Poland
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Poznan University of Physical Education
Temporomandibular Joint Disorders, Mastication Disorder
Altered MAstication Contribute to TMJ PAin
The cause of temporomandibular joint disorders remains unknown. It is considered multifactorial and includes physical (peripheral) and psychosocial (central) factors.
- Trial name
- MAPA (NCT03139994)
- Testing
- Diagnostic
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Santiago de Compostela
Laser Therapy, Periodontal Diseases
Odontogenic Graft Obtained From Human Tooth and Low Level Laser Therapy
This clinical trial aims to evaluate the effectiveness of an odontogenic graft obtained from extracted human teeth, with and without adjunctive low-level laser therapy (LLLT), on bone regeneration following posterior tooth…
- Conditions
- Laser Therapy, Periodontal Diseases, Bone Loss in Jaw, Alveolar Bone Loss
- Trial name
- NCT07615361
- Testing
- Autogenous Tooth-Derived Bone Graft, Low-Level Laser Therapy (LLLT)
- Where
- Turkey (Türkiye)
- Volunteers
- 21 people, healthy volunteers welcome
- Sponsor
- Istanbul Saglik Bilimleri University
Irreversible Pulpitis, Apical Periodontitis
Evaluation of iRoot SP as Root Canal Sealer: A Clinical Study
The purpose of this study was to evaluate the clinical and radiological outcomes of iRoot SP as a root canal sealer in comparison with AH Plus sealer within 1-year follow up.Patients needing root canal treatment were enrolled and…
- Trial name
- NCT02981693
- Testing
- Root canal sealer
- Volunteers
- 283 people, healthy volunteers welcome
- Sponsor
- Hui Chen
Apical Periodontitis, Post Endodontic Pain
Silver Nanoparticle-Reinforced Double Antibiotic Paste in Symptomatic Apical Periodontitis: A Randomized Controlled Trial
Background Apical periodontitis (AP) is an inflammatory condition of the periapical tissues. The Symptomatic Apical periodontitis (SAP) represents the active phase of the disease, presenting with pain and tenderness.
- Conditions
- Apical Periodontitis, Post Endodontic Pain, Periapical Healing, Inflammatory Biomarkers
- Trial name
- NCT07762599
- Testing
- silver nanoparticles reinforced double antibiotic paste, Double Antibiotic Paste
- Where
- India
- Volunteers
- 50 people
- Sponsor
- All India Institute of Medical Sciences
Surgical Complication, Paresthesia
Trial of Bilateral Sagittal Split Osteotomy Induced Paresthesia Using Ultrasonic vs. Reciprocating Saw Instrumentation
The aim of this prospective study is to analyze the postoperative paresthesias experienced in patients who undergo bilateral sagittal split osteotomies (BSSO) using an ultrasonic saw, versus a reciprocating saw.
- Conditions
- Surgical Complication, Paresthesia, Fracture, Nerve Injury
- Trial name
- NCT05205616
- Testing
- Sonopet ultrasonic saw, Reciprocating saw
- Where
- 2 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- University of California, San Francisco