Clinical trials: Joint
Renal Impairment, Gout
Evaluation of Colchicine and Nonsteroidal Anti-inflammatory Drug Combination Therapy and Renal Function in Gout Patients
Our findings are expected to provide real-world evidence of the renal-adverse effects of colchicine and NSAIDs combination therapy in patients with gout, which will guide healthcare professions in optimizing gout treatment…
- Conditions
- Renal Impairment, Gout, Colchicine Adverse Reaction, Nonsteroidals (NSAIDs)Toxicity
- Trial name
- NCT05006001
- Testing
- Colchicine and NSAID
- Volunteers
- 2,000 people, healthy volunteers welcome
- Sponsor
- En Chu Kong Hospital
Ankylosing Spondylitis, Work Productivity
Work Productivity and Social Activities In Patients With Ankylosing Spondylitis
The aim of this study is to evaluate the relationship between decrease in work productivity and social activities in patients with Ankylosing Spondylitis (AS) with disease activity, depression and quality of life together with…
- Trial name
- NCT04749537
- Where
- Turkey (Türkiye)
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Istanbul Physical Medicine Rehabilitation Training and Research Hospital
Ankylosing Spondylitis
Effect of IL17 Inhibitor in Comparison With Anti-TNF in Patients With Ankylosing Spondylitis
Ankylosing spondylitis (AS) is a chronic, inflammatory autoimmune disease characterized by axial bone inflammation. The main clinical manifestations include back pain and progressive spinal rigidity, as well as inflammation of…
- Trial name
- NCT06642207
- Testing
- CBC
- Where
- Egypt
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- Sohag University
Elbow Pain, Supracondylar Humerus Fracture
The Utilization of Ultrasound to Diagnose Pediatric Elbow Fractures
The goal of this intervention trial is to learn if a ultrasound diagnosis of elbow fractures can improve care in pediatric patients seen in the emergency room.
- Conditions
- Elbow Pain, Supracondylar Humerus Fracture, Radial Head Fractures, Radial Head or Neck Fractures
- Trial name
- NCT07212036
- Testing
- Ultrasound of the elbow, X-ray of elbow
- Where
- United States
- Volunteers
- 225 people, healthy volunteers welcome
- Sponsor
- Nemours Children's Clinic
Knee Injuries, Knee Osteoarthritis
Walking Gait Biomechanics Following Knee Joint Effusion
The purpose of this study is to determine the sensitivity of a wearable sensor to detect changes in knee joint loading using an experimental knee joint effusion as a model for a common clinical physiological alteration in joint…
- Trial name
- NCT03805464
- Testing
- Knee Joint Effusion
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Duke University
Rheumatoid Arthritis
Job Adaptation in Patients With Rheumatoid Arthritis
The specific aim of this study is to compare the rate of negative work role events in individuals with rheumatoid arthritis compared to healthy controls.
- Trial name
- NCT00412399
- Where
- 2 sites in United States
- Volunteers
- 244 people, healthy volunteers welcome
- Sponsor
- Hospital for Special Surgery, New York
Juvenile Idiopathic Arthritis
Methotrexate Alone vs Methotrexate + Etanercept for Minimal/Low Disease Activity in Juvenile Idiopathic Arthritis
This open labelled randomized controlled trial will be carried out at the University of Child Health and the Children's Hospital, Lahore consisting of 6 months .
- Trial name
- NCT07386587
- Testing
- Injection, Etanercept, 25 Mg (Code May Be Used for Medicare When Drug Administered Under the Direct Supervision of A Physician, Not for Use When Drug is Self Administered)
- Where
- Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Child Health Sciences and Children's Hospital, Lahore
Osteoarthritis, Knee
Clinical Outcomes With Omni Apex Ultracongruent Knee System
A prospective, matched case comparison of total knee arthroplasty with the OMNI Apex Ultracongruent vs. Triathlon® CS tibial insert vs. the Triathlon® PS tibial insert.
- Trial name
- NCT01367938
- Testing
- OMNI Apex Ultracongruent Knee Device
- Where
- United States
- Volunteers
- 69 people, healthy volunteers welcome
- Sponsor
- Spokane Joint Replacement Center
Temporomandibular Disorder, Oxidative Stress
Evaluation of Oxidative Stress and Inflammation Markers in Temporomandibular Disorders
Background: The occurrence of many diseases has been associated with oxidative stress and disruption of antioxidant mechanisms. Temporomandibular Joint(TMJ) Disorders are also thought to develop with the onset of the destructive…
- Conditions
- Temporomandibular Disorder, Oxidative Stress, Inflammation
- Trial name
- NCT05985733
- Testing
- Biochemical analysis
- Where
- Turkey (Türkiye)
- Volunteers
- 44 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
System; Lupus Erythematosus
Myofascial Techniques and Proprioceptive Neuromuscular Facilitation in Patients With Systemic Lupus Erythematosus.
Introduction. Systemic lupus erythematosus is an autoimmune disease. The musculoskeletal system is affected in 90% of patients. The most common manifestations are myalgias, arthralgias and arthritis. Objective.
- Trial name
- NCT06383104
- Testing
- Intervention
- Where
- Spain
- Volunteers
- 17 people, healthy volunteers welcome
- Sponsor
- Universidad Católica San Antonio de Murcia
Knee Osteoarthritis
Comparative Usability Evaluation of Sustained Acoustic Medicine (SAM) Devices and Topical Gel for OA Knee Pain
The purpose of this study is to evaluate the usability of the ultrasound devices and common pain relief gel. The ability of the three treatment approaches to reduce pain, stiffness, and functionality as measured by NRS scale and…
- Trial name
- NCT05050448
- Testing
- Sustained Acoustic Device with 2.5% Diclofenac Patch, 1% Diclofenac Topical Gel
- Where
- 3 sites in United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- ZetrOZ, Inc.
Osteoarthritis, Knee
Perineural Steroids for Peripheral Nerve Blocks
This study will look at the efficacy of dexamethasone for prolongation of peripheral nerve blocks.
- Trial name
- NCT02462148
- Testing
- Dexamethasone, Bupivacaine, Epinephrine
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Wake Forest University Health Sciences
Subacromial Impingement Syndrome
Effects of Exercise Trainings on Pain, Function and AHD in Patients With SPS
Abnormal reduction of the AHD has been considered as one of the possible mechanisms in the aetiology of subacromial pain syndrome.
- Trial name
- NCT03494192
- Testing
- Scapula Retraction Exercise Group, Scapula Retraction +Glenohumeral Rotational Exercise Group
- Where
- Turkey (Türkiye)
- Volunteers
- 49 people, healthy volunteers welcome
- Sponsor
- Hacettepe University
Arthralgia, Trouble Balancing
Even-Up to Minimize Secondary Site Pain For Ankle Fracture
Evaluating impact of use of Even-Up shoe wear device for patients treated in CAM boot walker for an ankle fracture. Randomized controlled trial, randomizing patients into control group with boot treatment only versus boot…
- Trial name
- NCT04164563
- Testing
- Even-Up
- Where
- United States
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Brigham and Women's Hospital
Osteoarthritis of Multiple Joints
Probiotic for Osteoarthritis
The gut microbiome appears to be a significant contributor to musculoskeletal health and disease. Microbiome composition and its functional implications have been associated with prevention of bone loss and/or reducing fracture…
- Trial name
- NCT03985709
- Testing
- Probiotic product
- Where
- Italy
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Fondazione Don Carlo Gnocchi ETS
Adolescent Athletic Performance, Muscle Strength Development
Effects of Back Squat Exercise with or Without Blood Flow Restriction in Healthy Adolescent Basketball Athletes
The goal of this clinical trial is to assess the effectiveness of Blood Flow Restriction (BFR) training compared to traditional high-intensity training in adolescent basketball players aged 16-18.
- Conditions
- Adolescent Athletic Performance, Muscle Strength Development, Jump Height Improvement, Ground Reaction Force (GRF) Enhancement
- Trial name
- BFR (NCT06684093)
- Testing
- Back squat with Blood flow restriction machine, Back squats
- Where
- Lebanon
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- St Joseph University, Beirut, Lebanon
Obesity, Eating Behavior
The Effects of Chia on Overweight/Obese Women
The purpose of the study is to examine the effect of chia seed consumption on body composition, blood pressure, blood glucose, satiety, mood, joint pain, and dietary displacement in overweight and obese females (18-45years).
- Conditions
- Obesity, Eating Behavior, Mood, Glucose
- Trial name
- NCT03233906
- Testing
- Chia Seeds- Salvia Hispanica
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- California State Polytechnic University, Pomona
Healthy Volunteers
A Pilot Open-Label Crossover Bioavailability Study of Celecoxib in Healthy Volunteers
A pharmacokinetic study in healthy volunteers to determine the relative bioavailability of three formulations of celecoxib to the approved formulation.
- Trial name
- NCT00813241
- Testing
- celecoxib reference formulation, celecoxib test formulation A1, celecoxib test formulation B2
- Where
- Singapore
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- Pfizer's Upjohn has merged with Mylan to form Viatris Inc.
Other Instability of Joint, Shoulder Region, Strain of Shoulder Muscle (Disorder)
The Effects of Muscle Characteristics on the Control of Shoulder Complex During Functional Movements
The movement control of shoulder joint relies not only on the glenohumeral joint, but also the critical contributions from scapulothoracic joint.
- Conditions
- Other Instability of Joint, Shoulder Region, Strain of Shoulder Muscle (Disorder), Movement Disorders
- Trial name
- NCT04176692
- Where
- Taiwan
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Tzu Chi University
Temporomandibular Dysfunction (TMD)
Efficacy of Physiotherapy in Patients With Temporomandibular Disorders.
Objective: To evaluate the efficacy of a manual therapy protocol composed of articulatory and myofascial techniques in patients with temporomandibular dysfunction (TMD).
- Trial name
- MT-ATM (NCT03555201)
- Testing
- Manual therapy, Regular treatment control.
- Where
- Spain
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- University of Valencia
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