Clinical trials: Joint Attention
Rheumatoid Arthritis, Ankylosing Spondylarthritis
Yuflyma® (Adalimumab), Patient Experience After Switching
Patient preference and experience can impact patients' adherence and persistence regarding a treatment, especially when switching.
- Conditions
- Rheumatoid Arthritis, Ankylosing Spondylarthritis, Axial Spondyloarthritis Without Radiographic Evidence of Ankylosing Spondylitis, Psoriatic Arthritis
- Trial name
- YU-MATTER (NCT05427942)
- Testing
- Adalimumab
- Where
- 2 sites in France
- Volunteers
- 300 people
- Sponsor
- Celltrion HealthCare France
Leukodystrophy, White Matter Disease
The Myelin Disorders Biorepository Project
The Myelin Disorders Biorepository Project (MDBP) seeks to collect and analyze clinical data and biological samples from leukodystrophy patients worldwide to support ongoing and future research projects.
- Conditions
- Leukodystrophy, White Matter Disease, Leukoencephalopathies, 4H Syndrome
- Trial name
- MDBP (NCT03047369)
- Where
- 23 sites in United States
- Volunteers
- 12,000 people
- Sponsor
- Children's Hospital of Philadelphia
Osteoarthritis, Knee, Obesity
Influence of Weight Loss or Exercise on Cartilage in Obese Knee Osteoarthritis Patients
Obesity and osteoarthritis (OA) co-exist in an increasing part of the population. The two diseases intertwine in several ways. The evolution in the population shows a tendency towards deterioration of both by increasing general…
- Trial name
- CAROT (NCT00655941)
- Testing
- Dietary instruction, Exercise
- Where
- Denmark
- Volunteers
- 192 people
- Sponsor
- Henning Bliddal
Autism Spectrum Disorder
VR for Joint Attention Support in ASD
The overall objective of this study is to determine the effectiveness of the Floreo VR Joint Attention Module in improving social communication skills in children with ASD.
- Trial name
- NCT04016701
- Testing
- Floreo Joint Attention Module, Regularly Scheduled Therapy
- Where
- United States
- Sponsor
- Floreo, Inc.
Prosthetic Joint Infection
Safety and Efficacy in Patients Treated for Hip or Knee PJI With Vancomycin and Tobramycin Joint Irrigation
Study Type Prospective, single-arm, open-label, multicenter (3 to 5 sites), interventional trial. Primary Study Objective The objective of the study is to determine the safety profile of local antibiotic irrigation for the…
- Trial name
- NCT03721328
- Testing
- vancomycin hydrochloride and tobramycin sulfate
- Where
- 4 sites in United States
- Volunteers
- 15 people
- Sponsor
- Osteal Therapeutics, Inc.
Sports Injury
The Gender-Specific Effect of Different Instruction Training
Feedback is incorporated into training programs to prevent injuries. The superiority of several feedback techniques is still debated and there is a need for gender specific studies.
- Trial name
- NCT06746454
- Testing
- Video Instructed Training Group, Verbal Combined Focus Instructed Training Group
- Where
- Turkey (Türkiye)
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Bahçeşehir University
Prosthetic Joint Infection
Abbreviated Protocol for Two-Stage Exchange
Study Type: A multi-site, parallel group, randomized trial. Study Objectives: The objective is to evaluate safety and determine preliminary efficacy of VT-X7 (Vancomycin and Tobramycin Exchanged over 7 Days).
- Trial name
- APEX (NCT04662632)
- Testing
- VT-X7 Treatment System with Tobramycin Sulfate, Standard of Care, Two-stage exchange arthroplasty
- Where
- 17 sites in United States
- Volunteers
- 76 people
- Sponsor
- Osteal Therapeutics, Inc.
Rheumatoid Arthritis
Association Between Methotrexate Erythrocyte Polyglutamate Concentration and Clinical Response in Rheumatoid Arthritis Patients Treated With Subcutaneous Injectable Methotrexate
Methotrexate (MTX) is the first-line treatment of rheumatoid arthritis (RA). In case of MTX failure, it is discussed to start a Biologic Disease-modifying Antirheumatic Drug (bDMARDs) according to the latest European…
- Trial name
- POLYGLU (NCT03445871)
- Testing
- Blood sample, CRQ
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Centre Hospitalier Universitaire de Saint Etienne
Autism
Joint Attention Intervention and Young Children With Autism
The purpose of this study is to investigate the effectiveness of an intervention aimed to increase joint attention in 2-4 year old children with autism. The study will be conducted in mainstream preschools in Norway.
- Trial name
- NCT00378157
- Testing
- Joint attention intervention
- Where
- Norway
- Volunteers
- 61 people
- Sponsor
- Ullevaal University Hospital
Soft Tissue Infections, Mediastinitis
Delafloxacin Plasma and Tissue Concentration in Patients With Skin, Soft Tissue, and Bone and Joint Infections.
The goal of this observational study is to measure how well the antibiotic delafloxacin penetrates into the blood and various body tissues in adult patients over 18 years old.
- Conditions
- Soft Tissue Infections, Mediastinitis, Osteomyelitis/Septic Arthritis, Prosthetic Joint Infection
- Trial name
- DELA-PLAT (NCT07426471)
- Testing
- delafloxacin
- Volunteers
- 20 people
- Sponsor
- IRCCS San Raffaele
Rheumatoid Arthritis
Pharmacokinetic Study to Compare the Blood Levels of Low vs High Metal Manufacture of Abatacept
The purpose of this study is to determine whether the blood levels of abatacept drug product manufactured using High Metals and using Low Metals are comparable in healthy subjects.
- Trial name
- NCT01221636
- Testing
- Abatacept
- Where
- United States
- Volunteers
- healthy volunteers welcome
- Sponsor
- Bristol-Myers Squibb
Medial Collateral Ligament Lesions, Knee Osteoarthritis
Comparison of the Efficacy of Ultrasound-Guided Injections of Saline, High-Concentration Dextrose, and Ligament Repair Agents for the Treatment of Medial Collateral Ligament Pathology in Degenerative Knee Osteoarthritis: A Randomized Double-Blind Trial.
The goal of this clinical trial is to evaluate the effectiveness of STABHA, high-concentration glucose water, and saline injections in treating knee osteoarthritis with medial collateral ligament lesions.
- Trial name
- NCT06620874
- Testing
- STABHA Injection, High-Concentration Glucose Water Injection, Saline Injection
- Volunteers
- 51 people
- Sponsor
- Chen Ting-an
Autism Spectrum Disorders, Autism
Measurement of Joint Attention Fluency
The purpose of this research is to study joint attention. Joint attention plays a critical role in social and language development in children with and without autism.
- Trial name
- NCT01643343
- Where
- United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- The Vista School
Pain, Osteoarthritis
Nociceptin Concentration in Synovial Fluid and Plasma
Nociceptin/Orphanin is a novel opioid peptide system associated with inflammatory response. Currently is it uncertain as to the presence of absence of nociceptin in synovial fluid of patients.
- Trial name
- NCT02528916
- Volunteers
- 22 people, healthy volunteers welcome
- Sponsor
- Milton S. Hershey Medical Center
Pain
Capsaicin Patches In Knee Osteoarthritis In Obese Patients
To assess the efficacy and safety of high concentration capsaicin patches in pain due to osteoarthritis (OA) of the knee in patients with obesity
- Trial name
- CHILI-OB (NCT03153813)
- Testing
- capsaicin 8% patches (Qutenza)
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Nadine ATTAL
Rheumatoid Arthritis
Proactive Therapeutic Drug Monitoring Based Adalimumab Therapy Optimization in Patients With Rheumatoid Arthritis
Current standard of care of rheumatoid arthritis (RA) management includes a routine clinical assessment of disease activity to adjust therapy.
- Trial name
- TDM-RA (NCT05460390)
- Testing
- Therapeutic drug monitoring (TDM)
- Where
- United States
- Volunteers
- 5 people
- Sponsor
- Boston Medical Center