Clinical trials: Joint Instability Syndrome
Hip Dysplasia, Hypermobility Syndrome
Dynamic Lycra Garments for Hip Dysplasia Feasibility Study
Dynamic lycra garments are deployed in rehabilitation and exercise to support unstable areas of the body, enhance sensory feedback to improve movement patterns, reduce fatigue and pain and improve function.
- Trial name
- HIPlycra (NCT07438873)
- Testing
- Lycra Shorts
- Volunteers
- 12 people
- Sponsor
- Royal National Orthopaedic Hospital NHS Trust
Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS)
Regenerative Medicine for Joint Hypermobility and Instability
This clinical trial is designed to evaluate whether a stepwise injection-based treatment approach can reduce pain and improve function in adults with joint hypermobility, connective tissue laxity, and joint instability.
- Conditions
- Ehlers-Danlos Syndrome Hypermobility Type (hEDS), Ehlers-Danlos Syndrome (EDS), Joint Hypermobility, Joint Instability
- Trial name
- NCT07688096
- Testing
- Dextrose 20% Prolotherapy, Autologous Platelet-Rich Plasma, Doxycycline Hyclate Injectable (Investigational)
- Volunteers
- 100 people
- Sponsor
- Manhattan Pain Medicine, PLLC
Temporomandibular Disorders (TMD), Temporomandibular Pain
Is the Combine Prolotherapy More Effective Than the Traditional Prolotherapy in Patients With Temporomandibular Joint Hypermobility?
1. Diagnosis and Indication You have been diagnosed with temporomandibular joint (TMJ) hypermobility and/or dysfunction, characterized by symptoms such as jaw clicking, locking, pain in the joint area, or difficulty in opening…
- Conditions
- Temporomandibular Disorders (TMD), Temporomandibular Pain, Hypermobility Syndrome (Disorder), Hypermobility, Joint
- Trial name
- NCT07020455
- Testing
- prolotherapy solution of 20% dextrose, Arthrocentesis with ringer solution
- Where
- Turkey (Türkiye)
- Volunteers
- 26 people
- Sponsor
- Karadeniz Technical University
Hypermobile Ehlers-Danlos Syndrome, Heavy Menstrual Bleeding
Identifying the Determinants of Bleeding and Hypermobility in Patients With Heavy Menstrual Bleeding
In this study, researchers want to learn about the connection between heavy bleeding issues and joint hypermobility (loose joints).
- Conditions
- Hypermobile Ehlers-Danlos Syndrome, Heavy Menstrual Bleeding, Hypermobility Syndrome (Disorder)
- Trial name
- NCT05685199
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- St. Jude Children's Research Hospital
Hypermobility, Joint, Hypermobility Syndrome
Exercise in Patients With Hypermobile Joints and Knee Pain
Pain associated with knee joint hypermobility is common in the adult population, but evidence on treatment is sparse. This study investigates if high-load resistance training is superior to usual care in improving…
- Conditions
- Hypermobility, Joint, Hypermobility Syndrome, Knee Discomfort
- Trial name
- HIPEr-Knee (NCT06277401)
- Testing
- Neuromuscular training for the knee, High-load strength training for the knee
- Where
- 2 sites in Denmark
- Volunteers
- 80 people
- Sponsor
- University of Southern Denmark
Rotator Cuff Syndrome, Shoulder Instability
Virtual Reality Intervention in Patients With Persistent Shoulder Pain
Shoulder pain is very common and can make daily activities difficult. Many people have shoulder pain for a long time, even after treatment.
- Conditions
- Rotator Cuff Syndrome, Shoulder Instability, Frozen Shoulder
- Trial name
- NCT07390227
- Testing
- Exercise with Virtual reality, education on shoulder pain, simulation de-briefing
- Where
- Netherlands
- Volunteers
- 30 people
- Sponsor
- HAN University of Applied Sciences
Osteochondral Lesion of Talus, Ankle Arthritis
Treatment Outcome After Ankle Joint Surgeries
Osteochondral lesion of talus (OLT), osteoarthrosis and impingement/instability syndrome are most common ankle joint pathologies.
- Conditions
- Osteochondral Lesion of Talus, Ankle Arthritis, Instability; Ankle (Ligaments) (Old Injury), Impingement Syndrome of Ankle
- Trial name
- NCT04132076
- Where
- Slovenia
- Volunteers
- 200 people
- Sponsor
- University Medical Centre Ljubljana
Ankle Sprains, Hypermobility Syndrome
Comparison of MBR + Suture Tape, MBR, and Anatomic Reconstruction for CLAI in GJL Cases: A Prospective Cohort Study
GJL is a risk factor for postoperative recurrent instability following an MBR for CLAI. BPR with suture tape augmentation and anatomic reconstruction may provide more strength and stability.
- Trial name
- NCT05698446
- Testing
- Modified Broström + Suture tape augmentation operation, Anatomic reconstruction operation, Open Modified Broström procedure
- Where
- China
- Volunteers
- 114 people
- Sponsor
- Peking University Third Hospital
Anterior Knee Pain Syndrome
10-year Follow-up After Tibial Tubercle Transposition
Patellofemoral pain is a common complaint especially in young adults. It can be caused by patellar maltracking. Part of this is a patella alta.
- Trial name
- TTTfollow-up (NCT05629754)
- Testing
- MRI, radiological assessment
- Where
- Netherlands
- Volunteers
- 32 people
- Sponsor
- Centre for Orthopaedic Research Alkmaar
Joint Hypermobility, Ehlers-Danlos Syndrome
Gait Retraining in Patients With Joint Hypermobility Syndrome/Hypermobile Ehlers Danlos Syndrome
This study evaluates the efficacy of gait retraining with biofeedback in the treatment of neuromusculoskeletal symptoms in patients with Joint Hypermobility Syndrome/Hypermobile Ehlers Danlos Syndrome.
- Conditions
- Joint Hypermobility, Ehlers-Danlos Syndrome, Hyperextension Knees
- Trial name
- NCT03575182
- Testing
- Gait retraining program
- Volunteers
- 12 people
- Sponsor
- University of South Florida
Joint Hypermobility Syndrome, Sleep
Sleep Characteristics in Infants With Joint Hypermobility
Joint hypermobility is defined as an increased range of motion in one or more joints compared to the normal range. The Beighton Scoring (BS) system is commonly used to distinguish individuals with generalized joint hypermobility…
- Conditions
- Joint Hypermobility Syndrome, Sleep, Infant
- Trial name
- NCT07121179
- Testing
- Beighton Scoring system, Brief Infant Sleep Questionnaire
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Nigde Omer Halisdemir University
ADHD, Benign Joint Hypermobility Syndrome
Evaluation of Benign Joint Hypermobility and Serum Prolidase Levels in Children Diagnosed With Attention-Deficit/Hyperactivity Disorder (ADHD) Compared to Healthy Controls
This cross-sectional observational study investigates the clinical and biochemical relationship between Attention-Deficit/Hyperactivity Disorder (ADHD) and Benign Joint Hypermobility Syndrome (BJHS) in pediatric patients.
- Conditions
- ADHD, Benign Joint Hypermobility Syndrome, ADHD - Attention Deficit Disorder With Hyperactivity, ADHD - Combined Type
- Trial name
- NCT07663383
- Where
- Turkey (Türkiye)
- Volunteers
- 171 people, healthy volunteers welcome
- Sponsor
- Antalya Training and Research Hospital
Hypermobility, Joint, Arthralgia
Association Between Hypermobility and Chronic Musculoskeletal Pain
Study hypothesis:- Benign joint hyper mobility syndrome which persists into adulthood is a special type of benign joint hyper mobility which is more likely to predispose to chronic musculoskeletal pain.
- Conditions
- Hypermobility, Joint, Arthralgia, Myofascial Pain Syndromes, Fibromyalgia
- Trial name
- HAMS (NCT01032863)
- Where
- India
- Volunteers
- 112 people, healthy volunteers welcome
- Sponsor
- Amrita Institute of Medical Sciences & Research Center
Rotator Cuff, Syndrome, Frozen Shoulder
Validation of a Kinematic Functional Shoulder Score Including Only Essential Movements
A lot of shoulder function evaluation scores exist but none has been universally accepted as a gold standard. Recent studies have demonstrated the potential of computerized movement analysis with embedded sensors for objective…
- Conditions
- Rotator Cuff, Syndrome, Frozen Shoulder, Humerus, Fracture, Other Instability of Joint, Shoulder Region
- Trial name
- NCT01431417
- Where
- Switzerland
- Volunteers
- 108 people, healthy volunteers welcome
- Sponsor
- Haute Ecole de Santé Vaud
Plantar Plate Tear, Metatarsalgia
Evaluation of Clinical and Functional Results After Operative Correction of Lesser Toe Deformities
The plantar plate is an important static stabilizer of lesser metatarsophalangeal joints, and disruptions of the plantar plate can lead to significant instability and lesser toe deformities.Our study proposes an inexpensive and…
- Conditions
- Plantar Plate Tear, Metatarsalgia, Lesser Metatarsophalangeal Joint Instability, Hammer Toe
- Trial name
- NCT04949685
- Testing
- plantar plate repair
- Where
- Taiwan
- Volunteers
- 18 people
- Sponsor
- National Taiwan University Hospital
Spinal Stenosis, Spinal Disease
Percutaneous Trans-facet Screw Fixation Under CT-scan Guidance for Remaining Symptoms at a Distance of Previous Spinal Surgery
Background : Segmental spinal instability after a laminectomy, and adjacent segment disease (ASD) at after an arthrodesis, are well-known concerns in spinal surgery, which may require re-interventions, usually by surgical…
- Conditions
- Spinal Stenosis, Spinal Disease, Zygapophyseal Joint Arthritis, Joint Instability
- Trial name
- NCT05525052
- Testing
- Trans-Facet fixation
- Where
- France
- Volunteers
- 24 people
- Sponsor
- Centre Hospitalier Universitaire de Nice
Patellofemoral Pain Syndrome, Patellar Instability
Assessment of the Safety and Performance of a Patellofemoral Brace
Decathlon has developed kneeSOFT500 product, which is a medical device intended to be used on the knee to keep a physical activity on a regular basis in case of patellofemoral pain syndrome or patellar instability.
- Trial name
- NCT04653753
- Testing
- kneeSOFT500
- Where
- 4 sites in France
- Volunteers
- 30 people
- Sponsor
- Decathlon SE
Patellofemoral Pain Syndrome, Hallux Valgus
The Additional Effect of Hallux Valgus Correction on Runners With First Ray Instability and Patellofemoral Pain Syndrome
The study purpose is to investigate the effectiveness of a program combining biomechanical taping with lower extremity neuromuscular exercises for runners with patellofemoral pain syndrome (PFPS) and hallux valgus
- Trial name
- NCT03468491
- Testing
- combined training, Proximal training
- Where
- Taiwan
- Volunteers
- 30 people
- Sponsor
- National Yang Ming Chiao Tung University
Hypermobility Syndrome Shoulder, Shoulder Pain Chronic
Shoulder Exercises in Hypermobile Patients With Shoulder Symptoms
Hypermobility Spectrum Disorder (HSD) is a recent diagnosis that covers generalised joint hypermobility with one or more secondary symptomatic musculoskeletal manifestations.
- Conditions
- Hypermobility Syndrome Shoulder, Shoulder Pain Chronic, Shoulder Luxation
- Trial name
- NCT03869307
- Testing
- Exercise
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- University of Southern Denmark
Ehlers-Danlos Syndrome, Craniocervical Syndrome
Opioid-Free Anesthesia for Patients With Joint Hypermobility Syndrome Undergoing Craneo-Cervical Fixation: A Case-series
Cranio-cervical instability (CCI) has been well identified in diseases regarding connective tissue, such as Ehlers-Danlos Syndrome/Hipermobility Type (EDS-HT).
- Trial name
- NCT04437589
- Where
- Spain
- Volunteers
- 42 people
- Sponsor
- Servei Central d'Anestesiologia