Clinical trials: Joint Osteoarthritis
Osteo Arthritis Knee and Hip
Test-Retest Reliability of a Submaximal Exercise Test in Patients With Hip and Knee Osteoarthritis
The aim is to evaluate the test-retest reliability of the primary care-adapted Ekblom-Bak submaximal ergometer bicycle test in patients with hip- and/or knee osteoarthritis (OA).
- Trial name
- NCT07383740
- Testing
- Submaximal cycle ergometer test-retest
- Where
- Sweden
- Volunteers
- 40 people
- Sponsor
- Vastra Gotaland Region
Osteoarthritis
JOINTS Study - Joint Replacement Outcome in Inpatient Rehabilitation Facilities and Nursing Treatment Sites
1. What are the characteristics of joint replacement patients (DRGs 209 \& 210) served in IRFs and SNFs? How are they similar or different? 2.
- Trial name
- JOINTS (NCT00499278)
- Testing
- Rehabilitation after joint replacement surgery
- Where
- United States
- Volunteers
- 2,384 people
- Sponsor
- MedStar National Rehabilitation Network
Knee Osteoarthritis
Mulligan Rotational Movement Versus Medial Gapping Technique in Patients With Knee Osteoarthritis
Knee osteoarthritis is a progressive degenerative and non-inflammatory joint disorder. Due to the extensive use and stress placed on knee joint, it is a common site for painful disorders such as knee osteoarthritis.
- Trial name
- NCT05338840
- Testing
- MULLIGAN ROTATIONAL MOVEMENT, Medial gapping technique
- Where
- Pakistan
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Osteo Arthritis Knee, Osteoarthritis, Knee
OA Optimization Program Pilot Trial
Total joint replacement is a highly successful treatment option for people affected by severe osteoarthritis (OA), however, the mismatch between resources and demand for this surgery means that many patients face long wait times…
- Conditions
- Osteo Arthritis Knee, Osteoarthritis, Knee, Osteoarthritis, Hip, Osteoarthritis
- Trial name
- NCT05389371
- Testing
- Alberta Healthy Living Program, Alberta Obesity Centre Program, Osteoarthritis advice
- Where
- Canada
- Volunteers
- 70 people
- Sponsor
- University of Calgary
Hip Osteoarthritis, Knee Osteoarthritis
Determining the Impact of a Physiotherapist-Led Primary Care Model for Hip and Knee Pain - A Pilot Trial
This is a pilot cluster randomized controlled trial to to evaluate the individual and health system impacts of implementing a new physiotherapist-led primary care model for hip and knee pain in Canada.
- Trial name
- NCT05736133
- Testing
- Physiotherapist-led primary care model for hip and knee pain, Usual physician-led primary care model for hip and knee pain
- Where
- Canada
- Volunteers
- 205 people, healthy volunteers welcome
- Sponsor
- Jordan Miller, PT, PhD
Osteoarthritis, Knee
The Effect of Cryotherapy in Pain Control, Function and Quality of Life in Individuals With Knee Osteoarthritis
The purpose of this study is to verify the effect of cryotherapy in pain control, function and quality of life in individuals with knee osteoarthritis.
- Trial name
- NCT02725047
- Testing
- Cryotherapy
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade Federal de Sao Carlos
Arthritis Knee, Knee Osteoarthritis
The Effect of a Methylprednisolone Taper on Outcomes Following Total Knee Arthroplasty
Pain control and early range of motion following total knee arthroplasty are essential for patient satisfaction. Intraoperative steroids (dexamethasone) have been shown to have a significant effect in controlling acute pain…
- Conditions
- Arthritis Knee, Knee Osteoarthritis, Pain, Postoperative
- Trial name
- NCT06489626
- Testing
- Methylprednisolone 4 milligram Tab, Dexamethasone injection
- Where
- 2 sites in United States
- Sponsor
- F. Johannes Plate
Osteoarthritis, Knee
Efficacy of High-Intensity Laser Therapy in Early-Stage Symptomatic Knee Osteoarthritis
This randomized, double-blind, sham-controlled clinical trial evaluated the effectiveness of high-intensity laser therapy (HILT) in patients with early-stage symptomatic knee osteoarthritis.
- Trial name
- HILT-ESCOA (NCT07859878)
- Testing
- High-Intensity Laser Therapy (HILT), Standardized Home Exercise Program
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Ege University
Osteoarthritis of Knee, Osteoarthritis Of Hip
Mobile Technology to Support Physical Therapy Exercise
Osteoarthritis is the leading cause of disability in the U.S, particularly in older adults. Exercise is an evidence-based treatment option that improves pain and disability outcomes in adults with osteoarthritis, but adherence to…
- Trial name
- MyTherEx (NCT03428893)
- Testing
- Mobile Application
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- University of Vermont
Osteoarthritis
Impact of Hand Osteoarthritis on Arterial Stiffness
Patients affected by osteoarthritis (OA) have an increase overall mortality compared to the general population, mainly due to cardiovascular diseases.
- Trial name
- NCT02167906
- Testing
- arterial stiffness measurement
- Where
- France
- Volunteers
- 80 people
- Sponsor
- University Hospital, Montpellier
Knee Osteoarthritis
Muscle Activation in Knee Osteoarthritis
Muscle activity, as a possible fundamental cause of functional limitation, has been extensively investigated in knee osteoarthritis (KOA).
- Trial name
- NCT05870033
- Testing
- Electromyography (EMG) measurement
- Where
- Hungary
- Volunteers
- 70 people
- Sponsor
- University of Pecs
Osteoarthritis, Hip, Hip Injuries
The Effect of a Telerehabilitaion Program on Gait and Balance in Patients After Hip Surgery
The purpose of the present study is to examine whether an intervention plan based on exercise through remote rehabilitation system leads to improvement in characteristics of walking and balance among patients after hip…
- Trial name
- NCT02451085
- Testing
- training with video therapy, conventional exercise
- Where
- Israel
- Volunteers
- 40 people
- Sponsor
- Reuth Rehabilitation Hospital
Knee Osteoarthritis, Total Knee Arthroplasty
Prediction of Postoperative Outcomes After TKA Using Instrumented Insoles and DNN
This multicenter prospective observational study aims to evaluate whether preoperative clinical variables and wearable sensor-derived gait features can predict postoperative improvement after total knee arthroplasty (TKA).
- Trial name
- NCT07367789
- Testing
- Instrumented Insole Gait Assessment
- Where
- South Korea
- Volunteers
- 200 people
- Sponsor
- Yonsei University
Osteoarthritis, Hip, Femoroacetabular Impingement
Early Feasibility Study of Cartilage Defect Repair
Any patient aged 14 or older up to 64 years of age with hip disease, resulting in loss of articular cartilage integrity on the femoral head (e.g., femoroacetabular impingement or other structural deformity), has failed…
- Conditions
- Osteoarthritis, Hip, Femoroacetabular Impingement, Osteonecrosis, Legg-Calvé-Perthes Disease
- Trial name
- NCT06823089
- Testing
- ReNew Hip Implant
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- Cytex Therapeutics, Inc.
Osteoarthritis
The Effects of Disease Management Training and Telephone Counseling Service for Elderly Patients With Osteoarthritis
The study will be conducted to determine the difference on functional status, self-efficacy, and quality of life between groups with and without telephone counseling and training on disease management for participants.
- Trial name
- NCT04816474
- Testing
- Online education and Phone Counseling Service
- Where
- 2 sites in Turkey (Türkiye)
- Volunteers
- 52 people
- Sponsor
- KTO Karatay University
Osteoarthritis, Knee, Arthropathy of Knee
Total Knee Arthroplasty: Fast Track Protocol is the Future?
Fast-track total knee arthroplasty (TKA) is a well-established concept including optimized logistics and evidence-based treatment, focusing on minimizing surgical stress and improved post-operative recovery.
- Trial name
- FastTrack-G (NCT03869996)
- Testing
- fast track care protocol, standard care protocol
- Where
- Italy
- Volunteers
- 64 people, healthy volunteers welcome
- Sponsor
- Istituto Ortopedico Rizzoli
Hip Osteoarthritis, Avascular Necrosis of Hip
THA With and Without Computer Navigation
The goal of this observational study is to compare postoperative results between patients who had total hip arthroplasty (THA) with and without the use of a computer navigation program.
- Trial name
- NCT05871827
- Testing
- Intraoperative Fluoroscopic Computer Navigation
- Where
- United States
- Volunteers
- 234 people
- Sponsor
- Southeast Orthopedic Specialists
Osteoarthritis
Determination of Adipocytokine in Synovial Fluid of Osteoarthritis Patients
The purpose of this study is to determine the concentration of different adipocytokine (adiponectin, leptin, resistin, visfatin, osteopontin) and an inflammation classic markers as Interleukine 1 beta, tumor necrosis alfa…
- Trial name
- NCT01993342
- Testing
- arthrocentesis, ultrasonography of the knee
- Where
- Spain
- Volunteers
- 35 people
- Sponsor
- Parc Taulí Hospital Universitari
Primary Total Knee Arthroplasty, Intraosseous Morphine Injection
Effectiveness of Adding Morphine to Intraosseous Vancomycin for Pain Control in Total Knee Arthroplasty
Study investigators propose to investigate if a bony injection of pain medication during a knee replacement will help pain levels following primary knee replacement surgery. To investigate this, 86 patients will be enrolled.
- Conditions
- Primary Total Knee Arthroplasty, Intraosseous Morphine Injection, Knee Osteoarthritis
- Trial name
- NCT06716749
- Testing
- Morphine, Vancomycin
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- Carilion Clinic
Osteoarthritis, Pain
A Single-Blind Placebo Run-In Study of Venlafaxine for Activity-Limiting Osteoarthritis Pain
This will be a single-blind, placebo-run-in trial. Subjects will be informed that they may receive Venlafaxine or placebo during the course of the trial. All subjects will, in fact, receive placebo for the first two weeks.
- Trial name
- NCT00611676
- Testing
- Venlafaxine
- Volunteers
- 18 people
- Sponsor
- University of Washington