Clinical trials: Joint Osteoarthritis, open to volunteers
Osteoarthritis, Femoroacetabular Impingement Syndrome
Intra-articular Corticosteroid With Hyaluronic Acid Plus Physiotherapy for Hip Pathologies (NON-OP HIP)
Hip pathologies that cause pain and functional limitations are common in the general population. These can include femoroacetabular impingement (FAI), labral tears and mild osteoarthritis (OA) among others.
- Conditions
- Osteoarthritis, Femoroacetabular Impingement Syndrome, Labrum Injury of the Hip Joint
- Trial name
- NON-OP HIP (NCT06653985)
- Testing
- Hyaluronic and corticosteroid injection, Physical Therapy
- Where
- Canada
- Volunteers
- 100 people
- Sponsor
- ArthroBiologix Inc.
Osteoarthritis of the CMC-1 Joint
TRACE - Thumb Base Replacement Arthroplasty for Osteoarthritis.
Osteoarthritis in the base of the thumb is one of the most common forms of hand arthritis. It usually appears in middle age, particularly in women, and can cause significant pain and loss of function.
- Trial name
- TRACE (NCT07178223)
- Testing
- Arthroplasty CMC-1
- Where
- Sweden
- Volunteers
- 90 people
- Sponsor
- Karolinska Institutet
Osteoarthritis of Facet Joint of Lumbar Spine
Safety of Adipose-derived Regenerative Cells Injection for Treatment of Osteoarthritis of the Facet Joint
This is a prospective, randomized, active controlled, single site safety and efficacy study in subjects suffering from chronic lumber back pain due to facet joint osteoarthritis comparing a single ADRC injection generated with…
- Trial name
- NCT03513731
- Testing
- Adipose-derived stem cell injection, Corticosteroid injection
- Where
- 2 sites in United States
- Volunteers
- 40 people
- Sponsor
- InGeneron, Inc.
Lower Back Pain, Facet Joint Pain; Low Back Pain
Bone Enhanced Ultrasound (BEUS) Data Library Development Project
A common treatment for low back pain involves fluoroscopy-guided spinal facet joint injections and/or medial branch nerve blocks.
- Conditions
- Lower Back Pain, Facet Joint Pain; Low Back Pain, Osteoarthritis (OA)
- Trial name
- NCT07036653
- Testing
- spinal ultrasound
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- Queen's University
Arthropathy, Osteoarthritis
Antigravity Treadmill After Joint Arthroplasty
The study aims to evaluate the efficacy of antigravity treadmill training and body weight-supported treadmill training in the rehabilitation of elderly patients (60-75 years) following hip or knee arthroplasty.
- Trial name
- NCT07040878
- Testing
- Antigravity Treadmill Training, Body Weight-Supported Treadmill Training, Conventional rehabilitation
- Where
- Poland
- Volunteers
- 60 people
- Sponsor
- Wroclaw University of Health and Sport Sciences
Hip Osteoarthritis, Rheumatoid Arthritis
G7 Dual Mobility With Vivacit-E or Longevity PMCF
This study is a global, multi-center, prospective, non-controlled, non-randomized, post-market clinical follow-up study. The main objectives of this study are to confirm the long-term safety, performance, and clinical benefits of…
- Conditions
- Hip Osteoarthritis, Rheumatoid Arthritis, Joint Diseases, Avascular Necrosis
- Trial name
- NCT05548972
- Testing
- G7 Dual Mobility with Vivacit-E bearing, G7 Dual Mobility Longevity bearing
- Where
- 10 sites in United States, Belgium and 2 more
- Volunteers
- 358 people
- Sponsor
- Zimmer Biomet
Arthrosis of First Carpometacarpal Joint
Short-term Recovery After Trapeziectomy and TMC Prosthesis: a Diary Study
Rationale: The trapeziometacarpal (TMC) joint is one of the most common areas in the hand and wrist to develop osteoarthritis (OA).
- Trial name
- THUMB Diary (NCT06654349)
- Where
- Netherlands
- Volunteers
- 200 people
- Sponsor
- Reinier Haga Orthopedisch Centrum
Arthritis (E.G., Degenerative Joint Disease (DJD), Osteoarthritis, and Rheumatoid Arthritis (RA))
A Prospective, Pre-market, Multi-center Study of Insignia Hip Stem in THA to Determine Implant Survivorship and PROMS.
The purpose of this study is to evaluate the survivorship (revision rates) and patient reported outcomes (PROMs) following implantation of the Insignia hip stem in patients undergoing cementless total hip replacement surgery…
- Trial name
- NCT06108934
- Testing
- Hip stem prosthesis
- Where
- Australia
- Volunteers
- 313 people
- Sponsor
- Stryker Australia Pty Ltd.
Joint Pain
Genicular Nerve Phenol Neurolysis Versus Radiofrequency Ablation for Pain Relief in Grade 4 Knee Osteoarthritis
The goal of this clinical trial is to compare the efficiency and efficacy of genicular nerves blockade by chemical phenol neurolysis versus radiofrequency ablation in managing pain in patients suffering from grade IV KOA in term…
- Trial name
- NCT06864390
- Testing
- genicular nerve neurolysis
- Volunteers
- 114 people
- Sponsor
- Ain Shams University
Temporomandibular Joint Condition Post Longstanding Mouth Opening During Dental Procedure Using Rubber Dam, TMJ Disc Disorder
Evaluation of Temporomandibular Joint Condition Post Longstanding Mouth Opening by Rubber Dam
This Clinical and radiographic study will be designed to evaluate the temporomandibular joint condition post longstanding mouth opening during dental procedure using rubber dam.
- Conditions
- Temporomandibular Joint Condition Post Longstanding Mouth Opening During Dental Procedure Using Rubber Dam, TMJ Disc Disorder, Osteoarthritis, Myofacial Pain
- Trial name
- NCT06487819
- Testing
- Application of a rubber dam during dental treatments for varying durations.
- Where
- Egypt
- Volunteers
- 300 people, healthy volunteers welcome
- Sponsor
- Al-Azhar University
Osteoarthritis, Knee, Knee Osteoarthritis
Prospective Functional, Gait, and Outcome Comparison Study of Medial Pivot Versus Single Radius Design for Total Knee Arthroplasty
Patients with degenerative joint disease can effectively be treated with a primary total knee replacement to reduce pain and improve function in their daily lives.
- Conditions
- Osteoarthritis, Knee, Knee Osteoarthritis, Osteoarthritis Knees Both, Osteoarthritis Knee Left
- Trial name
- NCT04814082
- Testing
- MicroPort Evolution Medial-Pivot Knee System (Cruciate-substituting), Stryker Triathlon Tritanium Knee System (Condylar Stabilizing)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- LifeBridge Health
Temporomandibular Joint Osteoarthritis
Intra-articular Allocetra in Osteoarthritis of the of the Temporomandibular Joint (TMJ)
This study is a single center trial to assess the safety and initial efficacy of intra-articular administration of Allocetra to patients with Temporomandibular Joint Osteoarthritis (TMJ-OA)
- Trial name
- NCT06748651
- Testing
- Allocetra
- Where
- Israel
- Volunteers
- 6 people
- Sponsor
- Dr. Amit Druyan
Osteoarthritis of the Hip or Knee, Joint Arthroplasty
Effects of Vitamin D Supplementation on Postoperative Rehabilitation in Hip and Knee Osteoarthritis Patients
The goal of this clinical trial is to learn if vitamin D supplementation affects postoperative rehabilitation in osteoarthritis patients who underwent joint arthroplasty.
- Trial name
- NCT06747559
- Testing
- Vitamin D
- Where
- China
- Volunteers
- 300 people
- Sponsor
- Second Affiliated Hospital, Zhejiang University, School of Medicine
Knee Osteoarthritis
Genicular Artery Embolisation for Knee Osteoarthritis II
This clinical study is designed as a double-blind sham controlled randomised trial with the option of sham group crossover to receive the GAE treatment at 6 months after unblinding.
- Trial name
- GENESISII (NCT05423587)
- Testing
- Genicular Artery Embolisation, Genicular Artery Injection
- Where
- United Kingdom
- Volunteers
- 110 people
- Sponsor
- Varian, a Siemens Healthineers Company
Osteoarthritis, Osteo Arthritis Knee
Adipose-Derived Biocellular Regenerative Therapy for Osteoarthritis
Use of Biocellular and cellular approaches to treatment of Osteoarthritis (OA), musculoskeletal aging processes, pain, and degenerative changes are to be studied with minimally invasive protocols, and non-pharmaceutical means to…
- Conditions
- Osteoarthritis, Osteo Arthritis Knee, Osteo Arthritis Shoulders, Osteoarthritis of Multiple Joints
- Trial name
- GARM-MSK-ALD (NCT04238143)
- Testing
- Tissue Stromal Vascular Fraction (tSVF) Arm 1, PRP Concentrate Arm 1, Tissue Stromal Vascular Fraction (tSVF) Arm 2
- Where
- 2 sites in United States
- Volunteers
- 100 people
- Sponsor
- Healeon Medical Inc
Degenerative Hip Joint Disease, Post-traumatic Osteoarthritis
Safety and Performance Assessment of the SYMBOL Range of Medical Devices in Patients Underlying Total Hip Arthroplasty
The purpose of this post-market clinical follow up study is to assess the safety and effectiveness of the SYMBOL range of medical devices.
- Conditions
- Degenerative Hip Joint Disease, Post-traumatic Osteoarthritis, Hip Arthritis, Femoral Neck Fractures
- Trial name
- NCT05227924
- Testing
- Total hip arthroplasty (primary or revision)
- Where
- 9 sites in France
- Volunteers
- 747 people
- Sponsor
- Dedienne Sante S.A.S.
Joint Diseases
Post Market Clinical Follow-Up Study for PROFEMUR® Preserve Classic Femoral Stem
Sponsor is conducting this post market clinical study to evaluate the safety and effectiveness of its PROFEMUR® Preserve Classic Femoral Stem.
- Trial name
- NCT04147559
- Testing
- Total Hip Arthroplasty Implant
- Where
- 2 sites in United States
- Volunteers
- 150 people
- Sponsor
- MicroPort Orthopedics Inc.
Joint Diseases, Osteoarthritis
Post Market Clinical Follow-Up Study for EVOLUTION® NitrX™ Keeled Tibia and EVOLUTION® NitrX™ CS/CR Femur With Cruciate Sacrificing Insert
MicroPort Orthopedics Inc. (MPO) plans to market the EVOLUTION® NitrX™ Non-Porous Keeled Tibia and EVOLUTION® NitrX™ CS/CR Non-Porous Femur with the EVOLUTION® Cruciate Sacrificing (CS) Tibial Insert globally, including in the…
- Conditions
- Joint Diseases, Osteoarthritis, Arthritis Knee, Avascular Necrosis
- Trial name
- NCT04816773
- Testing
- EVOLUTION® NitrX™
- Where
- 2 sites in United States, United Kingdom
- Volunteers
- 150 people
- Sponsor
- MicroPort Orthopedics Inc.
Joint Diseases
EVOLUTION® Revision STEMMED CS Post Market Clinical Follow-up Study Protocol
MicroPort (MPO) is conducting this PMCF study to evaluate the safety and effectiveness of its EVOLUTION® Revision Tibial System and EVOLUTION® Revision STEMMED CS Femur with the EVOLUTION® MP CS Tibial Insert.
- Trial name
- NCT06142669
- Testing
- EVOLUTION® Revision Tibial System and EVOLUTION® Stemmed CS Femur with the EVOLUTION® MP CS Tibial Insert
- Where
- Italy
- Volunteers
- 45 people
- Sponsor
- MicroPort Orthopedics Inc.
Joint Disease
Post Market Clinical Follow-Up Study Protocol for PROCOTYL® C Acetabular Components
MicroPort Orthopedics (MPO) is conducting this post market clinical follow-up (PMCF) study to evaluate the safety and efficacy of its total hip arthroplasty (THA) components marketed in the European Union (EU).
- Trial name
- NCT03576573
- Testing
- PROCOTYL® C
- Where
- Germany
- Volunteers
- 143 people
- Sponsor
- MicroPort Orthopedics Inc.