Clinical trials: Joint Pain
Toothache, Temporomandibular Joint Disorders
Multimodal Assessment of Sensory Processing and Brain Features in Patients With Chronic Orofacial Pain
This proposal will investigate pain modulatory mechanisms and brain functional and structural characteristics using multiple MRI modalities in persistent dentoalveolar pain disorder (PDAP) patients with and without…
- Trial name
- NCT02630771
- Testing
- Pressure pain threshold
- Where
- United States
- Volunteers
- 39 people, healthy volunteers welcome
- Sponsor
- University of Minnesota
Knee Osteoarthritis
A Study to Evaluate the Safety and Efficacy of CNTX-6970 in Subjects With Knee Osteoarthritis Pain.
The primary objective of this study is to evaluate the safety and efficacy of CNTX-6970 for the treatment of pain related to OA of the knee compared to placebo.
- Trial name
- NCT05025787
- Testing
- CNTX-6970
- Where
- 16 sites in United States
- Volunteers
- 55 people
- Sponsor
- Maurizio Fava, MD
Neuropathic Pain, Osteo Arthritis Knee
WHIRLPOOL FOR OSTEOARHRITIS
Both neuropathic and nociceptive mechanisms may contribute to the OA pain experience. Aims: The aim of this study was to determine the efficacy of warm whirlpool on pain, disability, quality of life (QoL) and sleep for patients…
- Conditions
- Neuropathic Pain, Osteo Arthritis Knee, Sleep Disorder
- Trial name
- NCT03299114
- Testing
- Whirlpool
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ufuk University
Morton Neuroma
Is Ultrasonography Comparable to MRI for the Detection of Morton Neuroma of the Foot?
Patients with Morton neuroma of the foot will undergo either ultrasonography or MRI. The results will be compared. In case of surgery, the pathology report will be compared with the ultrasonographic or MRI findings.
- Trial name
- NCT00284414
- Testing
- Ultrasonography or MRI
- Sponsor
- University Hospital, Ghent
Knee Pain, Patellofemoral Pain Syndrome
Mikhled Knee Exercise Program With and Without Stecco Fascial Manipulation Effect in Patellofemoral Pain Syndrome
To compare the effects of the Mikhled Knee Exercise Program with and without Stecco Fascial Manipulation on pain, range of motion, and functional outcomes Patellofemoral Pain Syndrome.
- Conditions
- Knee Pain, Patellofemoral Pain Syndrome, Patellofemoral Pain (PFPS), Fascial Manipulation
- Trial name
- MKEP (NCT07716163)
- Testing
- Mikhled Knee Exercises with Stecco Fascial Manipulation, Mikhled Knee Exercise Program (MKEP)
- Where
- Pakistan
- Volunteers
- 58 people
- Sponsor
- Riphah International University
Knee Pain Chronic
A+HA Premium Oral Hyaluronic Acid Drink Functional Evaluation Trial for Delaying Joint Pain
Evaluate the effect of A+HA premium oral hyaluronic acid drink on relieving knee pain.
- Trial name
- NCT07800676
- Testing
- A+HA premium oral hyaluronic acid drink
- Where
- Taiwan
- Volunteers
- 60 people
- Sponsor
- Taipei Medical University
Trigeminal Neuralgia, Temporomandibular Disorder
Comorbid Painful TMD Among Trigeminal Neuralgia
An observational study following up with trigeminal neuralgia patients to understand their comorbid facial pain condition, specifically temporomandibular disorder.
- Conditions
- Trigeminal Neuralgia, Temporomandibular Disorder, Myofascial Pain, Trigeminal Neuropathy
- Trial name
- TNTMD (NCT05914558)
- Testing
- Clinical appointment
- Where
- 2 sites in United States
- Sponsor
- University of Minnesota
Rotator Cuff Tear
Rotator Cuff Repair Using Standard Double Row Technique With Platelet Rich Fibrin Membrane vs. Standard Double Row Technique
This study is a single-blind, randomized study evaluating the 6 month and 2 year outcomes of patients treated with arthroscopic rotator cuff repair using one of two techniques.
- Trial name
- RCRPRFM (NCT02256891)
- Testing
- PRFM, Double Row
- Where
- United States
- Volunteers
- 97 people, healthy volunteers welcome
- Sponsor
- HealthPartners Institute
Hip Pain Chronic, Osteoarthritis, Hip
Pericapsular Nerve Group Block Added to Intra-articular Corticosteroid Injection in the Treatment of Hip Pain
Osteoarthritis (OA) is a leading cause of chronic musculoskeletal pain and functional disability worldwide, affecting an increasing number of people.
- Trial name
- PENGandIAI (NCT07427238)
- Testing
- Intra-articular injection, Intra-articular injection + PENG blok
- Where
- Turkey (Türkiye)
- Volunteers
- 50 people
- Sponsor
- Saglik Bilimleri Universitesi
Osteo Arthritis of the Knee
Lubricin-inspired Osteoarthritis Treatment: a Unique Solution
This goal of this open label study is to evaluate the safety and tolerability of a single intra-articular administration of ABR1 in adults with knee osteoarthritis with a KL grade from 2 to 4.
- Trial name
- LOTUS (NCT07611708)
- Testing
- ABR1
- Where
- Australia
- Volunteers
- 25 people
- Sponsor
- Pleryon Therapeutics (Hangzhou) Limited
Arthritis, Joint Pain
The Effect of LDL557 on Improving Degenerative Arthritis in the Elderly
This project is to conduct a clinical trial of SYNBIO TECH INC.'s LDL557 capsule for joint protection. To understand the improvement of joint discomfort and inflammation after supplementation, we hope to provide an updated choice…
- Trial name
- NCT06658821
- Testing
- LDL557-HK capsule
- Where
- Taiwan
- Volunteers
- 100 people
- Sponsor
- Chung Shan Medical University
Sciatica, Spinal Stenosis of Lumbar Region
Prolotherapy Versus Epidural Steroid Injections (ESI) for Lumbar Pain Radiating to the Leg
The hypothesis is that in the treatment of low back pain (LBP) radiating to the leg, the long-term results of prolotherapy are more effective than those of the current conventional treatment: epidural steroid injections (ESI).
- Conditions
- Sciatica, Spinal Stenosis of Lumbar Region, Degeneration of Lumbar or Lumbosacral Intervertebral Disc
- Trial name
- NCT01934868
- Testing
- prolotherapy solution of 20% dextrose, Epidural Steroid Injection
- Where
- Israel
- Volunteers
- 110 people
- Sponsor
- Hadassah Medical Organization
Shoulder Pain, Knee Pain
Cryoneurolysis for Knee and Shoulder Pain in an Inpatient Setting
The purpose of the study is to measure the outcomes of a standard care, an ultrasound guided mini-invasive percutaneous procedure, performed on recent stroke patients on reduces pain, increases function \& quality of life The…
- Conditions
- Shoulder Pain, Knee Pain, Spasticity, Pain
- Trial name
- NCT05674604
- Testing
- Cryoneurolysis
- Where
- Canada
- Volunteers
- 25 people
- Sponsor
- Vancouver Island Health Authority
Knee Osteoarthritis
Veteran Affairs Osteoarthritis Knee Study
A clinical study at the Dallas Veterans Affairs, is being proposed to test the efficacy of a novel electrical stimulation platform named the Pro-Sport Ultra® device by AVAZZIA to reduce pain and increase activity level in…
- Trial name
- NCT04698733
- Testing
- BEST™ HVPC microcurrent electrical stimulation Pro-Sport Ultra® device
- Where
- United States
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Avazzia, Inc
Low Back Pain
Technical Efficacy of a Direction Specific Radiofrequency Device in the Performance of Lumbar Medial Branch Neurotomies
The purpose of this study is to document the effectiveness of the Nimbus Multi-tined Expandable Electrode (MEE) Probe in carrying out the heating and ablation (cutting) of the small medial branch nerves that carry pain…
- Trial name
- NCT02120625
- Testing
- Lumbar MB RFN
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Nimbus Concepts, LLC
Ulcer
Efficacy and Safety Study of HZT-501 in Subjects Requiring Nonsteroidal Anti-Inflammatory Drug (NSAID) Treatment
The purpose of this study is to evaluate whether HZT-501 is effective in reducing the rate of development of ibuprofen-associated ulcers in patients who require long-term daily use of ibuprofen.
- Trial name
- NCT00450216
- Testing
- Ibuprofen/famotidine, Ibuprofen
- Volunteers
- 906 people
- Sponsor
- Amgen
Shoulder Pain, Rotator Cuff Tear
Efficacy of Interscalene Brachial Plexus Block With Liposomal Bupivacaine for Arthroscopic Shoulder Surgery
The purpose of this study is to compare the quality and duration of pain relief after shoulder surgery provided by a single injection of liposomal bupivacaine versus standard bupivacaine when administered as an interscalene…
- Trial name
- NCT01977352
- Testing
- Liposomal bupivacaine, Bupivacaine 0.25%
- Where
- United States
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- St. Luke's-Roosevelt Hospital Center
Axial Spondyloarthritis (AxSpA), Spondyloarthritis (SpA)
Multicenter Validation of the 2025 Classification Criteria for Axial Spondyloarthritis
This study aims to validate the 2025 ASAS-SPARTAN revised classification criteria for axial spondyloarthritis (axSpA) in the Chinese population through a multicenter, prospective, cross-sectional observational study.
- Conditions
- Axial Spondyloarthritis (AxSpA), Spondyloarthritis (SpA), Chronic Back Pain
- Trial name
- MVAS2025 (NCT07724847)
- Testing
- Diagnostic Assessment
- Where
- China
- Volunteers
- 247 people
- Sponsor
- Chinese PLA General Hospital
Subacromial Impingement Syndrome
Effect of Scapular Stabilization Exercises on Pain and Functional Outcomes in Subacromial Impingement Syndrome: A Randomized Controlled Trial
This randomized controlled study aims to evaluate the effects of scapular stabilization exercises on pain, shoulder function, and quality of life in patients with subacromial impingement syndrome.
- Trial name
- NCT07277868
- Testing
- Standard Physiotherapy
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Kanuni Sultan Suleyman Training and Research Hospital
Shoulder Impingement Syndrome
Efficacy of a Web App With Multimedia Animations to Teach Therapeutic Exercise in Shoulder Pain
The aim of this trial is to develop and evaluate a web app to teach patients about how to correctly perform a tailored program of shoulder exercises.
- Trial name
- NCT03554538
- Testing
- Web app exercises program, Exercise program
- Volunteers
- 100 people
- Sponsor
- Universidad Complutense de Madrid