Clinical trials: Keratectasia
Keratoconus, Post LASIK Keratectasia
Evaluating the Safety and Efficacy of the KXL System for Corneal Collagen Cross-Linking in Eyes Having Keratoconus
The objectives of this study are to evaluate the safety of and efficacy of the KXL system with vibeX Rapid (Riboflavin Ophthalmic Solution) for Corneal Collagen Cross-Linking in eyes having: 1. Keratoconus (KC) , 2.
- Trial name
- NCT02638376
- Testing
- 0.1% Riboflavin ophthalmic solution (KXL System With vibeX Rapid), simultaneous KXL and topography-guided transepithelial photorefractive keratectomy(PRK)
- Where
- Singapore
- Volunteers
- 66 people
- Sponsor
- Singapore Eye Research Institute
Tomography, Corneal Biomechanics
Long-term Safety and Effectiveness of LASIK-Xtra Compared to Conventional LASIK
Laser in situ keratomileusis (LASIK) is a widely used procedure for the correction of myopia and myopic astigmatism. Despite its high effectiveness and the general safety of the procedure, long-term safety and effectiveness…
- Conditions
- Tomography, Corneal Biomechanics, Manifest Ref, Endothelial Cells
- Trial name
- Xtra Lasik (NCT06857032)
- Where
- Germany
- Volunteers
- 12 people
- Sponsor
- University Clinic Frankfurt
Pellucid Marginal Corneal Degeneration, Keratoconus
A Study to Test the Potential of Brillouin Microscopy for Biomechanical Properties Measurements in Human Cornea
The purpose of this research study is to find out if the new Brillouin Ocular Scanner can measure the variation (difference) of the corneal elastic changes involved in the onset of corneal ectasia, induced by LASIK surgery and…
- Conditions
- Pellucid Marginal Corneal Degeneration, Keratoconus, Keratectasia
- Trial name
- NCT03220529
- Testing
- Brillouin Ocular Scanner
- Where
- 2 sites in United States, Switzerland
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Massachusetts General Hospital
Keratoconus
Evaluating Collagen Cross-Linking (CCL) Treatment in Norway
The purpose of this study is to assess safety, efficacy and stability of riboflavin-UV induced cross-linking of corneal collagen in reducing the progression of keratecatasia and in improving visual acuity.
- Trial name
- NCT00435799
- Testing
- corneal cross-linking (CCL), Riboflavin/dextran eyedrops, UV-X system
- Where
- 2 sites in Norway
- Volunteers
- 40 people
- Sponsor
- Ullevaal University Hospital
Keratoconus, Ectasia
Collagen Cross-Linking for Keratoconus/Ectasia With and Without Intacs
This study will determine the efficacy of collagen cross linking for progressive keratoconus and ectasia after lasik. It will try and determine which is a more effective treatment: collagen cross linking alone or collagen cross…
- Trial name
- NCT01081561
- Testing
- Riboflavin
- Where
- United States
- Volunteers
- 600 people
- Sponsor
- Yaron S. Rabinowitz M.D.