Clinical trials: Keratinized Tissue
Edentulous Jaw, Missing Teeth
The Effect of a Suturing Technique on the Gingival Tissues Around Dental Implants
There is general agreement that a thick zone of the keratinized tissues around implants promotes accurate prosthetic procedures, permits oral hygiene maintenance, resists recession, and enables esthetic blending with surrounding…
- Conditions
- Edentulous Jaw, Missing Teeth, Gingival Diseases
- Trial name
- NCT06496776
- Testing
- Choukroun's technique
- Where
- Syria
- Volunteers
- 14 people
- Sponsor
- Damascus University
Gingival Recession, Localized, Keratinized Tissue
Effect of Modified Free Gingival Graft and Conventional Free Gingival Graft on Gingival Recession
The aim of this clinical study is to understand whether the modified free gingival graft technique is superior to the conventional free gingival graft: Will gingival recession completely close in modified free gingival grafting…
- Conditions
- Gingival Recession, Localized, Keratinized Tissue, Free Gingival Graft
- Trial name
- NCT06737120
- Testing
- Mod-fgg, Fgg
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- AYSE HUMEYRA ORUC
Gingival Recession, Mucogingival Surgery
V-Reverse Suture Technique Compared to Traditional Anchored Sling Suture in Treating Multiple Gingival Recession
The goal of this split-mouth pilot study is to study the effect of two different suturing techniques in root coverage using coronally advanced flap tunnel in multiple adjacent recession cases to see which technique will give…
- Trial name
- NCT07602829
- Testing
- coronally advanced tunnel with v-reverse suture, coronally advanced tunnel with anchored sling suture
- Where
- Jordan
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- King Abdullah University Hospital
Mucogingival Deformity - Insufficient Keratinized Tissue
A Clinical Trial to Evaluate Kerecis Oral™ Compared to Autogenous Free Gingival Graft (AFGG) Tissue to Augment Gingival Soft Tissue and Wound Healing
The purpose of this study is to evaluate Omega-3 Wound™ as an alternative to autogenous free gingival grafts harvested from the palate to treat human subjects with insufficient KT (< 2 mm)
- Trial name
- NCT03664401
- Testing
- Kerecis Oral™, Free Gingival Graft
- Volunteers
- 6 people
- Sponsor
- Kerecis Ltd.
Free Gingival Graft, Soft Tissue Augmentation Around Dental Implants
Clinical Evaluation of a Modified Technique for Free Gingival Graft Stabilization Using Titanium Fixation Tacs Around Implants Versus Conventional Suturing Technique
The aim of this randomized, controlled, parallel-grouped, clinical trial is to evaluate the width of keratinized gingiva after free gingival graft stabilized by titanium fixation tacs compared to traditional suturing.
- Conditions
- Free Gingival Graft, Soft Tissue Augmentation Around Dental Implants, Inadequate Keratinized Tissue Around Dental Implants
- Trial name
- NCT07019428
- Testing
- Free gingival graft stabilized by Titanium fixation tacs, Free gingival graft stabilized by sutures
- Where
- Egypt
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- Cairo University
Peri-implantitis, Soft Tissue Augmentation at Dental Implants
Adjunctive Keratinized Mucosa Augmentation in Peri-Implantitis
This study aims to increase the width and thickness of peri-implant keratinized mucosa (KM) by transferring a properly dimensioned free gingival graft (FGG) from the palatal donor site and to evaluate its effect as an adjunctive…
- Trial name
- NCT07471386
- Testing
- Submucosal debridman + saline irrigation, Free gingival graft surgery
- Where
- Turkey (Türkiye)
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Gazi University
Keratinized Mucosa Deficiency, Peri-implant Soft Tissue
Apical Flap Repositioning vs. Mucosa Excision With Free Gingival Grafts for Peri-Implant Keratinized Mucosa Augmentation
The goal of this clinical trial is to learn which surgical technique works better to increase the amount of firm gum tissue (called keratinized mucosa) around dental implants in adults.
- Conditions
- Keratinized Mucosa Deficiency, Peri-implant Soft Tissue, Dental Implants
- Trial name
- FGGIF (NCT07772414)
- Testing
- Free gingival graft with apical flap repositioning, Free gingival graft with vestibular mucosa excision
- Where
- Spain
- Volunteers
- 50 people
- Sponsor
- University of Barcelona
Edentulous Alveolar Ridge
The Impact of the Adequacy of Keratinized Mucosa on Peri-implant Tissue Health and Patient-reported Outcomes
This study aims to conduct a cross-sectional study to compare the differences in clinical indices, patient-reported outcomes, and levels of inflammatory factors in peri-implant gingival crevicular fluid between sites with…
- Trial name
- NCT07124416
- Testing
- No intervention
- Where
- China
- Volunteers
- 150 people
- Sponsor
- The Dental Hospital of Zhejiang University School of Medicine
Gingival Recession, Lack of Keratinized Attached Peri-implant Mucosa
Gain of Keratinized Mucosa Around Teeth and Dental Implants Using a Combination of Strip Gingival Graft and Acellular Dermal Matrix
This study is to compare the two techniques to achieve change in the tissue quality at areas of lack of Keratinized Tissue (KT) using soft tissue grafting with autogenous graft material (Free Gingival Graft)(FGG) vs Strip…
- Conditions
- Gingival Recession, Lack of Keratinized Attached Peri-implant Mucosa, Thin Gingiva
- Trial name
- NCT04920136
- Testing
- Strip Free gingival graft (SGG) + Acellular Dermal Matrix graft (ADM), Free Gingival graft
- Where
- United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Gingival Recession, Lack of Keratinized Gingiva (Disorder)
Progenitor Potential of Mesenchymal Stem Cells in Palatal Tissue Harvested From Molar and Premolar Sites
The primary purpose of this protocol is to isolate, investigate and compare the regenerative and differentiation potential of mesenchymal stem cells (MSC's) in the gingival (gum) tissue harvested from two different locations from…
- Trial name
- NCT03570333
- Testing
- progenitor potential of Gingival Mesenchymal cells
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Dental Implants, Transplants
Efficacy of Gingival Grafts During the Implantation Process on the Peri-implant Mucosa
This study aims to compare the changes in the peri-implant mucosa during the application of two soft tissue grafting methods, which are free gingival graft (FGG) and connective tissue graft (CTG) taken from the palatine in terms…
- Trial name
- NCT06065254
- Testing
- Efficacy of free gingival grafts during in the increasing of peri-implant keratinized tissue width and soft tissues thickness, Efficacy of connective tissue grafts during in the increasing of peri-implant keratinized tissue width and soft tissues thickness, No types of grafts will be made to improve the quality of the peri-implant mucosa
- Where
- Syria
- Volunteers
- 18 people
- Sponsor
- Damascus University
Lack of Keratinized Tissue
Fixation of Free Gingival Graft Using Tissue Tacks vs Criss-cross Sutures
Tissue tacks may improve graft stability but their effect on pain is unclear. The study compares tacks and sutures by measuring pain, stability, healing success, and patient comfort.
- Trial name
- NCT07823374
- Testing
- Criss cross sutures, Tissue tacs
- Where
- Egypt
- Volunteers
- 16 people
- Sponsor
- October University for Modern Sciences and Arts
Peri-Implantitis, Peri-implant Mucositis
Lingual Keratinized Tissue in Fully Edentulous Patients and Its Impact on Implant Health
Cross-sectional study involving the measurement of the width of lingual keratinized tissue (in the implant locations) in fully edentulous patients restored with dental implants.
- Conditions
- Peri-Implantitis, Peri-implant Mucositis, Recession, Gingival
- Trial name
- NCT06166017
- Testing
- Exposure to minimal amount of lingual keratinized tissue width
- Volunteers
- 90 people, healthy volunteers welcome
- Sponsor
- George Eastman Dental Hospital, Italy
Dental Implant
Peri-implant Soft Tissue Phenotype and Early Marginal Bone Loss After Dental Implant Placement
This prospective observational cohort study evaluated the relationship between peri-implant soft tissue characteristics and early marginal bone loss following dental implant placement.
- Trial name
- NCT07769125
- Where
- Turkey (Türkiye)
- Volunteers
- 39 people
- Sponsor
- Karabuk University
Lack of Keratinized Gingiva, Mucogingival Deformity - Insufficient Keratinized Tissue
Star Matrix vs Autogenous Graft for Gingival Augmentation: Split-Mouth RCT
This split-mouth randomized controlled clinical trial will test whether a ready-to-use collagen membrane (Star Matrix) can widen the protective band of gum tissue (keratinized gingiva) as effectively as the standard free gingival…
- Trial name
- NCT07440303
- Testing
- Starmatrix collagen membrane, Autogenous gingival graft
- Where
- United States
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Harvard Medical School (HMS and HSDM)
Periodontitis, Periodontal Diseases
Influence of Flap Position Following FibReORS
There is lack of data in literature on keratinized tissue increase after FibReORS in relation to primary flap position. This study has been designed as a split-mouth randomized trial to assess the influence of flap position after…
- Trial name
- NCT05140681
- Testing
- FibReORS with apically positioned flap (apical position), FibReORS with apically positioned flap (crestal position)
- Where
- Italy
- Volunteers
- 16 people, healthy volunteers welcome
- Sponsor
- University of Turin, Italy
Keratinized Mucosa, Keratinized Tissue
Efficacy of Collagen Matrix for Peri-implant Soft Tissue Phenotype Modification
A stable band of keratinized mucosa (KM) around dental implants is thought to minimize tissue recession and provide resistance against mechanical, chemical, and microbial challenges, thereby preserving peri-implant tissue health.
- Trial name
- XCM versus FGG (NCT07056959)
- Testing
- Soft tissue substitute for peri-implant phenotype modification, Control Group - Free gingival graft for soft tissue augmentation
- Where
- United Arab Emirates
- Volunteers
- 30 people
- Sponsor
- Mohammed Bin Rashid University of Medicine and Health Sciences
Keratinized Mucosa
The Impact of Peri-implant Soft Tissue Properties on Patient-reported and Clinically Assessed Outcomes
The objective of this study is to evaluate patient discomfort while performing oral hygiene (OH) around implants with and without keratinized mucosa (KM) and assess peri-implant soft tissue esthetic satisfaction and other…
- Trial name
- NCT03396536
- Testing
- Evaluation of KM
- Volunteers
- 43 people
- Sponsor
- Tufts University
Gingival Recession, Mucogingival Surgery, Keratinized Tissue Deficiency
Gingival Unit Graft Versus Free Gingival Graft: 18-Month Digital Color Analysis
The purpose of this retrospective clinical study is to compare the long-term aesthetic integration and clinical outcomes of two periodontal plastic surgery techniques: Gingival Unit Grafting (GUG) and Free Gingival Grafting…
- Trial name
- NCT07706257
- Testing
- Gingival Unit Grafting, Conventional Free Gingival Grafting
- Where
- Turkey (Türkiye)
- Volunteers
- 40 people
- Sponsor
- Bezmialem Vakif University
Acute Oroantral Communication
Buccal Periosteal Inversion Flap vs Buccal Advancement Flap for Acute Oro-Antral Communication Closure
This prospective randomized controlled clinical trial will compare the Buccal Periosteal Inversion Flap (BUPI) with the Buccal Advancement Flap (BAF) for the primary surgical closure of acute oro-antral communications (OAC)…
- Trial name
- NCT07884331
- Testing
- Buccal Periosteal Inversion Flap, Buccal Advancement Flap
- Where
- Austria
- Volunteers
- 22 people
- Sponsor
- Medical University of Graz