Clinical trials: Ketamine Adverse Reaction
Ketamine Adverse Reaction
Evaluation of Ketamine as Sedative Agent in Endoscopic Retrograde Cholangiopancreatography (ERCP)
This is a study evaluating the usage of Ketamine as sedative agent in ERCP. The usage of Ketamine will be compared to the standard sedation in our center, which is Midazolam in combination with Pethidine as analgesia.
- Trial name
- NCT04490031
- Testing
- Ketamine Hydrochloride
- Where
- Malaysia
- Volunteers
- 140 people, healthy volunteers welcome
- Sponsor
- Universiti Kebangsaan Malaysia Medical Centre
Ketamine Adverse Reaction, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy
Does a Single Intravenous Dose of Ketamine Reduce the Need for Supplemental Opioids in Post-Cesarean Section Patients?
Pain control after cesarean delivery is associated with improved breastfeeding and infant rooming-in times. In addition, inadequate analgesia leads to elevated plasma catecholamine concentrations, which negatively affect every…
- Conditions
- Ketamine Adverse Reaction, Effects of; Anesthesia, Spinal and Epidural, in Pregnancy, Complication of Labor and/or Delivery
- Trial name
- NCT00486902
- Testing
- Ketamine
- Where
- United States
- Volunteers
- 188 people
- Sponsor
- Northwestern University
Dream, Day, Ketamine Adverse Reaction
The Impact of Preoperative Suggestion on Dreaming
Recent studies have shown that positive preoperative suggestions can significantly influence the quality of dreams and reduce the incidence of unpleasant dreams during sedation with agents like ketamine and propofol.
- Conditions
- Dream, Day, Ketamine Adverse Reaction, Propofol Adverse Reaction
- Trial name
- NCT06609538
- Testing
- Control Group, Suggestion Group
- Where
- South Korea
- Volunteers
- 250 people, healthy volunteers welcome
- Sponsor
- Wonkwang University Hospital
Acute Pain Due to Trauma, Analgesia
Fentanyl OR Esketamine for Traumatic PAIN (FORE-PAIN) Trial
Fentanyl and esketamine are both standard of care for treatment of acute severe traumatic pain in the prehospital setting in the Netherlands. However, it is not known whether they are equally effective and safe.
- Conditions
- Acute Pain Due to Trauma, Analgesia, Fentanyl, Esketamine
- Trial name
- FORE-PAIN (NCT06051227)
- Testing
- Fentanyl Citrate, Esketamine
- Where
- Netherlands
- Volunteers
- 235 people
- Sponsor
- Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
Pain, Postoperative, Ketamine Adverse Reaction
Neuropsychiatric and Cardiovascular Side Effects in Ketamine Analgesic Infusions
Evaluation of neuropsychiatric and cardiovascular side effects of low dose ketamine analgesic infusion for postoperative pain
- Trial name
- NCT03525912
- Testing
- Ketamine
- Where
- Colombia
- Volunteers
- 101 people
- Sponsor
- Universidad de Antioquia
Chronic Pain
OBSERVATIONAL STUDY OF THE MANAGEMENT OF PATIENTS WITH CHRONIC PAIN
The aim of this study is to evaluate the safety of use, benefits and risks of repeated use of ketamine for each patient with chronic pain in different structures of pain management.
- Trial name
- OKAPI (NCT03319238)
- Testing
- ketamine
- Where
- France
- Volunteers
- 1,000 people
- Sponsor
- University Hospital, Clermont-Ferrand
Tonsillectomy, Adenoidectomy
Effect of Intranasal Midazolam Versus Ketamine Midazolam Combination as a Premedication on the Occurrence of Postoperative Respiratory Adverse Events
The aim of this study is to investigate the effect of addition of intranasal ketamine to midazolam compared to midazolam alone as a premedication on the occurrence of PRAEs
- Conditions
- Tonsillectomy, Adenoidectomy, Drug-Related Side Effects and Adverse Reaction
- Trial name
- NCT06122948
- Testing
- The midazolam group, The midazolam ketamine group
- Where
- Egypt
- Volunteers
- 200 people
- Sponsor
- Kasr El Aini Hospital
Propofol, Ketamine
Propofol-Ketamine Versus Sevoflurane for Laryngeal Mask Anesthesia in Pediatric Cardiac Catheterization
Children undergoing cardiac catheterization will be given anesthesia using either a combination of propofol and ketamine or sevoflurane gas. The time taken to fall asleep will be recorded.
- Conditions
- Propofol, Ketamine, General Anesthetic Drug Adverse Reaction
- Trial name
- NCT07907796
- Testing
- Ketamine-Propofol, Sevoflurane
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Rawalpindi Institute of Cardiology
Pain, Postoperative, Ketamine Adverse Reaction
Efficacy of Ketamine in Post Anesthesia Recovery Room
Observational study to assess efficacy of IV ketamine bolus when used in the post anesthesia recovery unit for uncontrolled pain despite use of opioids.
- Conditions
- Pain, Postoperative, Ketamine Adverse Reaction, Pain, Refractory, Pain, Intractable
- Trial name
- NCT04701008
- Testing
- Ketamine
- Where
- Canada
- Volunteers
- 143 people, healthy volunteers welcome
- Sponsor
- University of Alberta
Failed Moderate Sedation During Procedure, Ketamine Adverse Reaction
Intranasal Ketamine for Pediatric Procedural Sedation: a Feasibility Study
The purpose of this study is to evaluate the feasibility of intranasal ketamine for adequate sedation of children undergoing minor procedures in the Emergency Department.
- Trial name
- NCT03067974
- Testing
- Ketamine Hcl 100Mg/Ml Inj
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- University of Arizona
Opioid Analgesic Adverse Reaction
Cardiovascular Protection Conservative Effects of Esketamine Versus µ-opioid Receptor Agonists in General Anesthesia
Pain is 'a double-edged sword', disturbing daily life of the sufferers and activating the intrinsic protective mechanisms. Transient receptor potential vanilloid 1 (TRPV1), play such role as 'a double agent', transmitting the…
- Trial name
- NCT04553536
- Testing
- Esketamine, Sulfentanil or/and Remifentanil
- Where
- China
- Volunteers
- 1,000 people
- Sponsor
- Second Hospital of Shanxi Medical University
Pain, Ketamine Adverse Reaction
Cardiovascular Safety After Continuous Ketamine Infusion
Observational study that evaluate the cardiovascular and neuropsychiatric side effects of ketamine analgesic infusions for acute pain
- Conditions
- Pain, Ketamine Adverse Reaction, Postoperative Pain
- Trial name
- NCT03979105
- Testing
- Ketamine
- Where
- 2 sites in Colombia
- Volunteers
- 300 people
- Sponsor
- Universidad de Antioquia
Thoracic Surgery
Epidural Levobupivacaine-sufentanil Versus Epidural Levobupivacaine and Intravenous Ketamine
Thoracic epidural analgesia is often proposed to thoracotomized patients. A local anesthetic and an opioid are generally associated to produce an epidural analgesia.
- Trial name
- NCT01320475
- Testing
- Sufentanil, Ketamine
- Where
- France
- Volunteers
- 2 people
- Sponsor
- Hopital Foch
Adverse Effect of Drugs and Medicaments in Therapeutic Use, Adverse Effects in the Therapeutic Use of Anaesthetics
The Effect of Opioid Free Anesthesia in Bariatric Surgeries
This is a prospective randomized controlled study that will be carried out on morbid obese patients admitted to Tanta University hospitals for laparoscopic bariatric surgeries.
- Trial name
- Opioidfree (NCT04048200)
- Testing
- Fentanyl, Dexmedetomidine Ketamine
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Tanta University