Clinical trials: Kidney Calculi
Pain, Urinary Stone
Prospective Randomized Controlled Trial for Pain Relief After Office Ureteral Stent Removal
This is a prospective randomized double-blind controlled trial assessing the benefits of intramuscular ketorolac before or immediately after office ureteral stent removal.
- Conditions
- Pain, Urinary Stone, Urinary Calculi
- Trial name
- NCT04112160
- Testing
- Ketorolac, normal saline
- Where
- United States
- Volunteers
- 125 people
- Sponsor
- University of Texas Southwestern Medical Center
Kidney Stones
Trial Comparing Three Different Devices for Kidney Stone Removal During Percutaneous Surgery
The investigators plan to compare three different devices that are used to break up large kidney stones during surgery for removal to see if one is faster or more efficient than the others.
- Trial name
- NCT00952315
- Testing
- Cyberwand, Stonebreaker, Lithoclast Select
- Where
- 10 sites in United States, Canada
- Volunteers
- 270 people
- Sponsor
- Indiana Kidney Stone Institute
Calcium Oxalate Urolithiasis
Oxalobacter Formigenes Colonization and Urinary Oxalate Excretion
The purpose of this research study is to assess the efficacy of ingesting a small amount of the harmless bacterium Oxalobacter formigenes in establishing residence in the guts of healthy participants and to determine whether this…
- Trial name
- NCT03752684
- Testing
- Moderately high oxalate/low calcium diet non-colonized, Oxalobacter formigenes, Moderately high oxalate/low calcium diet colonized
- Where
- United States
- Volunteers
- 26 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Kidney Stone, Pain, Postoperative
Perioperative Pregabalin in Ureteroscopy
This is a randomized, placebo-controlled, double-blinded study examining the use of perioperative pregabalin in ureteroscopy with stent placement.
- Conditions
- Kidney Stone, Pain, Postoperative, Addiction, Opioid Use
- Trial name
- NCT04122196
- Testing
- Pregabalin 300mg
- Where
- United States
- Volunteers
- 118 people
- Sponsor
- University of Missouri-Columbia
Kidney Stones
Trial Comparing Dual Probe Ultrasonic Lithotripsy to a Single Probe Ultrasonic Lithotripsy
Percutaneous nephrolithotomy (PNL), in conjunction with intracorporeal lithotripsy, allows for the rapid removal of any kidney stone regardless of size.
- Trial name
- NCT00351351
- Testing
- Cyberwand, single probe ultrasonic
- Where
- 7 sites in United States, Canada
- Volunteers
- 70 people
- Sponsor
- Indiana Kidney Stone Institute
Kidney Stones
Occlusion Balloon vs. 5FR Ureteral Catheter
Occlusion Balloon catheter provides the ability to occlude the exit of the kidney pelvis during percutaneous nephrolithotomy (PCNL) and potentially prevents the migration of stone fragments into the ureter.
- Trial name
- NCT06798753
- Testing
- Occlusion Balloon Catheter, 5FR Ureteral Catheter
- Where
- United States
- Volunteers
- 108 people
- Sponsor
- Icahn School of Medicine at Mount Sinai
Kidney Stones
Trial of Randomized Antibiotic Administration in Percutaneous Nephrolithotomy
The Investigators objective is to compare the clinical efficacy of a single-day protocol with a short-course protocol for PCNL. The investigator hope is to reduce the use of possibly unnecessary prolonged antibiotic use, reduce…
- Trial name
- NCT02579161
- Testing
- cephalosporins, Fluoroquinolones, Clindamycin
- Where
- 2 sites in United States
- Volunteers
- 98 people, healthy volunteers welcome
- Sponsor
- Northwell Health
Kidney Stone
Opioid Free Management After Ureteroscopy
The purpose of this research study is to compare how well two medications work to control post-operative pain.
- Trial name
- NCT03872843
- Testing
- Norco 5milligram-325milligram Tablet, Ibuprofen 400 MILLIGRAM in 1 TABLET ORAL TABLET, FILM COATED
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Wake Forest University Health Sciences
Kidney Stone, Renal Stone
Comparison of Laser Lithotripsy With and Without Steerable Ureteroscopic Renal Evacuation (SURE)
The purpose of the study is to compare the effects, good and/or bad, of a treatment for removing kidney stones called the SURE procedure for stone evacuation to the standard treatment using a basket for stone removal.
- Conditions
- Kidney Stone, Renal Stone, Urolithiasis
- Trial name
- NCT04519294
- Testing
- SURE, Standard Ureteroscopy (Basketing)
- Where
- 11 sites in United States
- Volunteers
- 132 people
- Sponsor
- Calyxo, Inc.
Kidney Calculi
MOSES Lithotripsy Technology Applied to Stone Fragmentation During Ureteroscopy
To determine if the effects of MOSES laser modulation technology can improve the safety and efficiency to laser fragmentation resulting in decreased total laser time, reduced potential for injury to the patient, and total OR time…
- Trial name
- NCT03995758
- Testing
- MOSES
- Where
- United States
- Volunteers
- 116 people
- Sponsor
- Indiana University
Postoperative Pain Management, Urolithiasis
The Use of Intranasal Ketoralac for Pain Management (Sprix)
Despite an overall reduction in the perioperative complication rate, post operative pain management after ureteroscopic removal of stones (URS) remains a major factor delaying discharge of patients.
- Trial name
- NCT01736358
- Testing
- Intranasal Ketoralac
- Where
- United States
- Volunteers
- 50 people
- Sponsor
- Montefiore Medical Center
Renal Stone, Nephrolithiasis
Impact Ureteral Sheath Design During Ureteroscopy
The purpose of this study is to assess whether one of two ureteral access sheaths is safer for patients undergoing ureteroscopy. Both sheaths are FDA approved devices and commercially available.
- Conditions
- Renal Stone, Nephrolithiasis, Urolithiasis
- Trial name
- NCT03349099
- Testing
- Cook Flexor, Boston Scientific Navigator
- Volunteers
- 95 people
- Sponsor
- The Cleveland Clinic
Ureterolithiases
Tamsulosin for Urolithiasis in the Emergency Dept
Urolithiasis is a disease that effects 12% of the population and its incidence is growing. In the US there are over 1.1 million visits annually to Emergency Departments for renal colic.
- Trial name
- STONE (NCT00382265)
- Testing
- tamsulosin
- Where
- 4 sites in United States
- Volunteers
- 512 people
- Sponsor
- Andrew Meltzer
Renal Stone
High Versus Low Power Settings During Ureteroscopic Laser Lithotripsy
The primary aim of the study is to compare the operative times following ureteroscopic lithotripsy for renal stones with Thulium Fiber Laser using low and high power settings.
- Trial name
- NCT05697250
- Testing
- Laser power settings (Thulium Fiber Laser)
- Where
- Norway
- Volunteers
- 150 people
- Sponsor
- Haukeland University Hospital
Children, Obstructive Uropathy
Ureteral Stents Versus Percutaneous Nephrostomy for Initial Urinary Drainage
To compare percutaneous nephrostomy (PCN) versus double J stent (JJ) as an initial urinary drainage in children
- Conditions
- Children, Obstructive Uropathy, Acute Renal Failure, Ureteric Stones
- Trial name
- NCT02055430
- Testing
- percutaneous nephrostomy insertion, bilateral double J ureteric stent, Definitive stone management
- Where
- Egypt
- Volunteers
- 90 people
- Sponsor
- Cairo University
Kidney Stone
Effect of Cola on Urinary Stone Risk Factors
Examine the effects of cola on risks of kidney stones
- Trial name
- NCT00289120
- Testing
- Cola beverage, Deionized water
- Where
- United States
- Volunteers
- 13 people, healthy volunteers welcome
- Sponsor
- Emory University
Nephrolithiasis
The Use of Belladonna and Opium Suppository in the Treatment of Postoperative Stent Pain
The purpose of this study is to determine if preemptive B\&O suppository placement will decrease post-operative pain in patients undergoing ureteral stent placement.
- Trial name
- B&O (NCT03332056)
- Testing
- Belladonna and Opium
- Volunteers
- 71 people
- Sponsor
- University of Washington
Ureteral Calculus, Ureterolithiasis
Silodosin Versus Tamsulosin for Treatment of Ureteral Stones
Ureteral calculi, commonly known as kidney stones, are a frequent cause of Emergency Department (ED) visits. These stones can get caught in the ureter (the tube connecting the kidney to the bladder) and cause symptoms including…
- Conditions
- Ureteral Calculus, Ureterolithiasis, Ureteral Stone
- Trial name
- NCT02369744
- Testing
- Silodosin, Tamsulosin
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- Albert Einstein Healthcare Network
Renal Calculus, Kidney Stones
Intravenous Ketorolac for Postoperative Pain in Percutaneous Nephrolithotomy
The purpose of this study is to determine whether continuous intravenous ketorolac infusion reduces pain in patients who are having percutaneous nephrolithotomy for kidney stone disease.
- Trial name
- NCT00765128
- Testing
- Ketorolac
- Where
- United States
- Volunteers
- 17 people
- Sponsor
- Mayo Clinic
Kidney Stones
Feasibility and Impact of a Decision Rule for Imaging of Emergency Department Patients With Suspected Kidney Stone
This is the third phase (feasibility and impact) of a three-phase project designed to derive, validate and test the feasibility and impact of implementing clinical decision support to safely limit the use of Computerized…
- Trial name
- NCT01869647
- Testing
- Ultra low dose CT scan, Regular CT or Low Dose CT scan, No imaging
- Where
- United States
- Volunteers
- 264 people
- Sponsor
- Yale University