Clinical trials: Kidney Donor
Renal Insufficiency
Atorvastatin in the Recipient's Kidney Graft From a Living Donor
Renal insufficiency is a priority disease in the health system, which may require renal replacement therapy based on kidney transplantation, which is considered as therapy of choice.
- Trial name
- ATORV15 (NCT02522117)
- Testing
- Atorvastatin
- Where
- Mexico
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Kidney Transplant
The Paired Donation Consortium Paired Donation Program
The purpose of the protocol is to increase the number of living donor transplants by eliminating immune incompatibilities between donors and recipients through paired donation.
- Trial name
- NCT00374400
- Where
- 2 sites in United States
- Volunteers
- 100 people, healthy volunteers welcome
- Sponsor
- University of Cincinnati
Living Donor Nephrectomy, Living Kidney Donation
Long-term Risk of Cardiovascular Disease in Living Kidney Donors
The investigative team will conduct a population-based, matched retrospective cohort study across Ontario, Alberta, and British Columbia using linked administrative healthcare databases to evaluate the long-term risk of major…
- Conditions
- Living Donor Nephrectomy, Living Kidney Donation, Living Kidney Donor, Living Kidney Donors
- Trial name
- NCT07431515
- Testing
- Nephrectomy
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Kidney Stones
Donors With Nephrolithiasis at the Time of Transplant Evaluation (DONATE). Long Term Follow-up.
We believe that kidney donors with kidney stones accepted for a donation do not have an increased risk of loss of kidney function and will not be at increased risk of symptomatic kidney stone events compared to donors without a…
- Trial name
- DONATE (NCT05519150)
- Testing
- low dose radiation abdomen/pelvis CT scan (stone protocol), Blood draw, 24 hour urine collection
- Where
- United States
- Volunteers
- 85 people, healthy volunteers welcome
- Sponsor
- Indiana University
Kidney Transplant, Kidney Donor
Transforming Curiosity Into Donation
This is a multi-step study that will first create a preliminary living donor drop-out risk index (LD-DROP) by retrospectively identifying factors that contribute to the discontinuation of living donor evaluation.
- Conditions
- Kidney Transplant, Kidney Donor, Drop Out, High Risk
- Trial name
- NCT07793890
- Testing
- Living Kidney Donor Support
- Where
- United States
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- The Methodist Hospital Research Institute
Living Kidney Donation, Living Kidney Donor
Long-Term Risk of Gout in Living Kidney Donors
This population-based, matched, retrospective cohort study will evaluate the long-term risk of gout among living kidney donors compared with matched healthy nondonors, using linked administrative health care databases from…
- Conditions
- Living Kidney Donation, Living Kidney Donor, Gout, Gout and Hyperuricemia
- Trial name
- NCT07546643
- Testing
- Living kidney donation
- Volunteers
- 50,000 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Kidney Transplant
Effects Of Propofol And Sevoflurane On Plasma Mirna Levels İn Living Kidney Donors
Surgical interventions and associated tissue trauma induce a complex systemic inflammatory stress response characterized by the activation of neuroendocrine, metabolic, and immunological systems.
- Trial name
- NCT07760402
- Testing
- Sevoflurane, propofol
- Where
- Turkey (Türkiye)
- Volunteers
- 34 people, healthy volunteers welcome
- Sponsor
- University of Gaziantep
Kidney Transplantation, Multiparametric Magnetic Resonance Imaging
Multiparametric MRI in a Prospective Cohort of Living Kidney Donors, Recipients, and Healthy Controls: Correlations With Markers of Renal Function, Fibrosis and Ageing
Development of renal fibrosis is the irreversible culmination of various renal diseases and independently predicts adverse outcomes. Currently renal fibrosis can only be diagnosed by performing a renal biopsy.
- Conditions
- Kidney Transplantation, Multiparametric Magnetic Resonance Imaging, Living Donors, Renal Fibrosis
- Trial name
- MpRenal (NCT06210555)
- Testing
- Renal transplantation, Living kidney donation
- Where
- 2 sites in Denmark
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Patrick Schjelderup
Renal Failure Chronic, Surgery
Laparoscopic Donor Nephrectomy Score, a New Scoring System for Preoperative Prediction of Difficulty of Laparoscopic Donor Nephrectomy
The goal of this multicenter observational study is to develope and validate a new scoring system for preoperative prediction of difficulty of Laparoscopic Donor Nephrectomy. Healthy living kidney donors will be enrolled.
- Trial name
- LAPDOCTOR (NCT05769686)
- Where
- Italy
- Volunteers
- 120 people, healthy volunteers welcome
- Sponsor
- Jacopo Romagnoli
Renal Transplant Donor of Left Kidney
Quadratus Lumborum Block Versus Epidural for Laparoscopic Nephrectomy Kidney Donor
This study aimed to compare Quadratus Lumborum Block to Epidural on Stress Response and Perioperative Cellular Immunological Function of Laparoscopic Nephrectomy Kidney Donor
- Trial name
- NCT03520205
- Testing
- Quadratus Lumborum Block, Continuous Epidural
- Where
- Indonesia
- Volunteers
- 62 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Renal Transplant Donor of Left Kidney
Enhanced Recovery Open Versus Laparoscopic Donor Nephrectomy
A phase III randomized trial conducted to compare recovery outcomes between laparoscopic and open donor nephrectomy within a specified enhanced recovery protocol
- Trial name
- MEnROL (NCT02699489)
- Testing
- Laparoscopic donor nephrectomy, Open donor nephrectomy
- Volunteers
- 224 people, healthy volunteers welcome
- Sponsor
- Mansoura University
Renal Disease
Remote Ischemic Preconditioning Living Donor Renal Transplant Protocol
In this study, patients undergoing live donor kidney transplantation will be allocated to the control group or remote ischemic preconditioning group (RIPC).
- Trial name
- NCT03084666
- Testing
- Zimmer ATS tourniquet system
- Where
- United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- University of Alabama at Birmingham
Living Donor Nephrectomy
Scrotal Surgery After Laparoscopic Donor Nephrectomy
This study will examine whether laparoscopic nephrectomy is associated with a higher long-term risk of receiving scrotal surgery in male living kidney donors compared to male nondonors from the general population who have similar…
- Trial name
- NCT06716723
- Testing
- Nephrectomy
- Where
- Canada
- Volunteers
- 9,878 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Chronic Kidney Disease
Effects of a Reduction in Kidney Function on Cardiovascular Structure and Function: A Prospective Study of Kidney Donors
Studies of patients with established kidney disease, even when this is mild, appear to show that they are at high risk of heart failure, stroke and sudden cardiac death.
- Trial name
- NCT01028703
- Where
- United Kingdom
- Volunteers
- 124 people, healthy volunteers welcome
- Sponsor
- University Hospital Birmingham NHS Foundation Trust
Complete and Accurate Statistical Data of 60 Patients, CYP3A5*3 Genotypes of 60 Donors and Recipients Were Analyzed Accurately
Analysis of the Effect of Donor CYP3A5 Gene Polymorphism on Early Tacrolimus Concentration and Postoperative Acute Renal Injury After Liver Transplantation
Tacrolimus is the most commonly used immunosuppressant for preventing and treating rejection after liver transplantation. However, its treatment window is narrow, the pharmacokinetic individual differences are large, routine dose…
- Conditions
- Complete and Accurate Statistical Data of 60 Patients, CYP3A5*3 Genotypes of 60 Donors and Recipients Were Analyzed Accurately, Postoperative Tacrolimus Concentrations Were Accurately Recorded in 60 Patients, According to the Diagnosis and Grading Criteria of Acute Kidney Injury, the Cases and Grading of Postoperative Acute Kidney Injury in 60 Patients Were Counted
- Trial name
- NCT06319391
- Testing
- CYP3A5*1*、CYP3A5*1*3, CYP3A5*3*3
- Where
- China
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Ziqiang Li
Post Operative Pain, Acute, Renal Transplant Donor of Left Kidney
Effectiveness of Thread Embedding Acupuncture Analgesia at the EX-B2 Point Combined With Standard Therapy After Laparoscopic Living Donor Nephrectomy
Kidney transplantation is the main option besides hemodialysis and continuous ambulatory peritoneal dialysis (CAPD) to prolong and improve the quality of life for patients with end-stage renal disease.
- Conditions
- Post Operative Pain, Acute, Renal Transplant Donor of Left Kidney, Quality of Life, Acupuncture Analgesia
- Trial name
- NCT06197620
- Testing
- Thread embedding acupuncture and standard therapy
- Where
- Indonesia
- Volunteers
- 6 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia
Living Kidney Donors
Pilot Prospective Study: Long-term Health of Living Kidney Donors
Kidney transplantation, a 'miracle' of modern medicine, is the preferred treatment option for End Stage Renal Disease compared to dialysis, patients who receive kidneys have a 70% reduction in risk of death, a dramatically…
- Trial name
- NCT00319579
- Where
- 15 sites in United States, Australia and 1 more
- Volunteers
- 330 people, healthy volunteers welcome
- Sponsor
- Amit Garg
Renal Insufficiency
Anti-inflammatory Effect of Atorvastatin on Graft Donor Kidney
Renal Insufficiency is a priority disease in health system, which may require renal replacement therapy based on renal transplantation, which is considered as therapy of choice.
- Trial name
- NCT02355704
- Testing
- Atorvastatin
- Where
- Mexico
- Volunteers
- 48 people, healthy volunteers welcome
- Sponsor
- Instituto Mexicano del Seguro Social
Kidney Diseases
Retrospective Study: Long-term Health of Living Kidney Donors
Kidney transplantation, is the preferred treatment option of end stage renal disease. Compared to dialysis, patients who receive kidneys have a 70% reduction in death, a dramatically improved quality of life and cost the health…
- Trial name
- NCT00319527
- Where
- 10 sites in Australia, Canada and 1 more
- Volunteers
- 311 people, healthy volunteers welcome
- Sponsor
- London Health Sciences Centre Research Institute OR Lawson Research Institute of St. Joseph's
Laparoscopic Nephrectomy
Comparison of Ventilation Distribution Between Tidal Volume 6ml/kgBW and 10ml/kgBW
This study aims to compare the ventilation Distribution between tidal Volume 6ml/kgBW and tidal volume 10ml/kgBW in laparoscopic nephrectomy patients
- Trial name
- NCT02834039
- Testing
- Tidal volume 6 ml/kgBW, Tidal volume 10 ml/kgBW
- Where
- Indonesia
- Volunteers
- 30 people, healthy volunteers welcome
- Sponsor
- Universitas Indonesia