Clinical trials: Kidney Functional
Diabetes, Healthy
A Trial Investigating the NN1250 Concentration-time Curve in Subjects With Various Degrees of Renal Impairment and in Subjects With Normal Renal Function
This trial was conducted in Europe. The aim of this clinical trial was to evaluate if the NN1250 (insulin degludec/insulin 454) concentration-time curve is altered to such an extent that the dose should be adjusted in subjects…
- Trial name
- NCT01006057
- Testing
- insulin degludec
- Where
- Hungary
- Volunteers
- 32 people
- Sponsor
- Novo Nordisk A/S
Hepatitis B, Chronic, Chronic Kidney Diseases
Renoprotective Effects of Telbivudine in Chronic Hepatitis B
Renal impairment is common in patients with chronic hepatitis B infection. For those taking nucleotide analogues, renal toxicity of adefovir disoproxil (ADV) and tenofovir disoproxil fumarate (TDF) is a significant concern in…
- Trial name
- NCT03778567
- Testing
- Telbivudine
- Where
- Hong Kong
- Volunteers
- 31 people
- Sponsor
- The University of Hong Kong
Healthy, Renal Impairment
A Study to Test How BI 456906 is Taken up in the Blood of People With and Without Kidney Problems
This study is open to adults aged between 18 and 80 years of age with a body mass index (BMI) of 20 to 40 kg/m2. People with or without kidney problems can take part in the study.
- Trial name
- NCT06352411
- Testing
- BI 456906
- Where
- 2 sites in Germany
- Volunteers
- 42 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
Ciliopathies, Nephronophthisis
Classification, Functional Stratification and Biomarkers in Ciliopathy (CILLICORIRCM)
The purpose of the C'IL-LICO RICM study is to develop innovative and transformative diagnostic and prognostic for patients suffering from ciliopathies leading to renal failure.
- Conditions
- Ciliopathies, Nephronophthisis, Senior-Loken Syndrome, Joubert Syndrome
- Trial name
- CILLICORIRCM (NCT04874909)
- Testing
- Blood sample, Urine sample
- Where
- France
- Volunteers
- 240 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Kidney Disease, Chronic, Endothelial Dysfunction
The Effect of Dietary Nitrates on Physical Performance and Vascular Function in Chronic Kidney Disease
The purpose of this study is to examine the effect of acute ingestion of a concentrated beetroot juice supplement on vascular function and exercise capacity in patients with moderate to severe chronic kidney disease
- Trial name
- NCT04103736
- Testing
- Beet It Sport Shot
- Where
- United States
- Volunteers
- 15 people
- Sponsor
- University of Delaware
Obese Subjects Who Will Undergo Gastric By-pass Surgery
Effect of Bariatric Surgery on Kidney Function
Primary hypothesis: A large reduction in weight is not associated with a change in accurately measured glomerular filtration rate (GFR) (51Chromium ethylenediaminetetraacetic acid plasma clearance (51Cr-EDTA)).
- Trial name
- GAS (NCT02138565)
- Testing
- Gastric by-pass surgery
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Steno Diabetes Center Copenhagen
Nephrectomy
Anesthesia and Acute Kidney Injury After Nephrectomy
This study investigates the influence of type of anesthesia on postoperative renal dysfunction in patients undergoing nephrectomy.
- Trial name
- NCT04474600
- Testing
- Propofol, Desflurane
- Where
- South Korea
- Volunteers
- 324 people
- Sponsor
- Seoul National University Hospital
Kidney Transplantation
Differentiating Everolimus Versus Sirolimus in Combination With Calcineurin Inhibitors in Kidney Transplant Patients
The investigators hypothesize that switching kidney transplant patients on tacrolimus/sirolimus long-term maintenance immunosuppressive drug regimens to tacrolimus/everolimus, will not only be safe, but will lead to better kidney…
- Trial name
- DESIRE (NCT02062892)
- Testing
- Everolimus, Sirolimus
- Sponsor
- University of Colorado, Denver
Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter
Combination Chemotherapy in Treating Patients With Advanced Cancer of the Urothelium and Decreased Kidney Function
RATIONALE: Drugs used in chemotherapy use different ways to stop tumor cells from dividing so they stop growing or die. Combining more than one drug may kill more cancer cells.
- Conditions
- Bladder Cancer, Transitional Cell Cancer of the Renal Pelvis and Ureter, Urethral Cancer
- Trial name
- NCT00005644
- Testing
- gemcitabine hydrochloride, paclitaxel
- Where
- 16 sites in United States
- Sponsor
- Eastern Cooperative Oncology Group
Hyperaldosteronism, Renal Insufficiency
The Water Intake Trail and Primary Aldosteronism Postoperation(WIT-PAP)
To investigate whether increasing water intake has renal protective effect on PA patients after surgical treatment.
- Trial name
- NCT04150666
- Testing
- Hydration
- Where
- China
- Sponsor
- Qifu Li
Hypotension Drug-Induced
Comparison of Different Protocols of Fluid Therapy in Severe Preeclamptic Patients Under Spinal Anesthesia
To compare the effect of two different protocol of fluid therapy in sever preeclamptic patients under spinal anesthesia : Hemodynamic and kidney function .
- Trial name
- NCT03478618
- Testing
- Lactated Ringer
- Volunteers
- 60 people
- Sponsor
- Assiut University
Liver Cirrhosis, Liver Failure
Effects on Plasma Exchange on Functional Capacity of Serum Albumin, Circulatory Dysfunction, Renal and Cerebral Function in Cirrhotic Patients With "Acute-on-chronic Liver Failure"
The purpose of this study is to evaluate the effects on plasma exchange with 5% albumin on albumin functional capacity, cardiocirculatory, renal and cerebral function in cirrhotic patients with "acute-on-chronic liver failure".
- Trial name
- NCT01201720
- Testing
- Plasma exchange with albumin
- Where
- Spain
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Instituto Grifols, S.A.
Renal Neoplasm, Renal Injury
The Effect of Remote Ischemic Preconditioning on Kidney Function in Patients Undergoing Partial Nephrectomy
This study is intended to evaluate the renal protective effect of Remote Ischemic Preconditioning (RIPC) in patients undergoing partial nephrectomy.
- Trial name
- NCT03273751
- Testing
- Remote Ischemic Preconditioning
- Where
- South Korea
- Volunteers
- 86 people
- Sponsor
- Seoul National University Hospital
Renal Transplant Recipients
Calcineurin Inhibitor-Free Immunosuppression in Renal Transplant Recipients at Low Immunogenic Risk
To compare renal function (51Cr-EDTA clearance) 12 months posttransplant, in primary renal allograft recipients (from cadaveric donor) at low immunogenic risk, 0 DR mis-match, receiving immunosuppressive therapy with A) Zenapax®…
- Trial name
- NCT00138970
- Testing
- Zenapax®, CellCept® and prednisolone, Sandimmun Neoral®, CellCept® and prednisolone
- Volunteers
- 70 people
- Sponsor
- University of Oslo School of Pharmacy
Cardiovascular Diseases, Chronic Kidney Disease Stage 3
Vitamin K to Slow Progression of Cardiovascular Disease Risk in Hemodialysis Patients
The life span of adults with end-stage renal disease is reduced, and cardiovascular disease (CVD) accounts for approximately half the deaths among those undergoing hemodialysis (HD).
- Conditions
- Cardiovascular Diseases, Chronic Kidney Disease Stage 3, Chronic Kidney Disease Stage 4, Chronic Kidney Disease Stage 5
- Trial name
- NCT03311321
- Testing
- Vitamin K2 (menaquinone-7; 360-mcg/d)
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Augusta University
Renal Function, Liver Transplant
Efficacy, Safety and Tolerability of Everolimus in Combination With Reduced Exposure Cyclosporine or Tacrolimus in Paediatric Liver Transplant Recipients.
This study was designed to assess the evolution of renal function and to collect efficacy, safety, and tolerability data of everolimus in co-exposure with reduced CNI in paediatric liver transplant recipients.
- Trial name
- NCT01598987
- Testing
- Introduction of everolimus with reduced cyclosporine or tacrolimus dose, the earliest 1 month and the latest 6 months after liver transplantation.
- Where
- 32 sites in United States, Australia and 10 more
- Volunteers
- 56 people
- Sponsor
- Novartis Pharmaceuticals
Chrnoic Haemodialysis Patients
Muscle Mass or Muscle Function as a prédictive Tools for Outtcomme in Chronic Dialysis Patients
Aim of this study is to compare the association of muscle mass and functionality with mortality among chronic haemodialysis the involvement of malnutrition inflammation and atherogenesis syndrome (increase in C reactive protein…
- Trial name
- NCT03845452
- Where
- France
- Volunteers
- 187 people
- Sponsor
- University Hospital, Montpellier
Kidney Disease
Elastography in Predicting Renal Outcome
There are two types of elastography: strain elastography assesses the degree of strain when applying a given amount of force to the skin.
- Trial name
- NCT06363032
- Testing
- elastography
- Where
- Taiwan
- Volunteers
- 500 people
- Sponsor
- National Taiwan University Hospital
Chronic Kidney Disease, Hyperuricemia
Compare the Renal Protective Effects of Febuxostat and Benzbromarone in CKD Chinese Patients
The purpose of this study is to determine whether febuxostat and benzbromarone could protect renal function in chinese, and which one could be better.
- Conditions
- Chronic Kidney Disease, Hyperuricemia, Abnormal Renal Function
- Trial name
- NCT02944214
- Testing
- Febuxostat, Benzbromarone
- Where
- China
- Volunteers
- 800 people
- Sponsor
- Shanghai 10th People's Hospital
Renal Insufficiency, Healthy
A Study in People With Normal Kidney Function and People With Reduced Kidney Function to Test How BI 1467335 is Processed in the Body
The primary objective of the current study is to investigate the influence of moderate renal impairment on the pharmacokinetics of multiple doses in comparison to a matched control group with normal renal function.
- Trial name
- NCT03302091
- Testing
- BI 1467335
- Where
- Germany
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- Boehringer Ingelheim
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.