Clinical trials: Kidney Functional
Stage 5 Chronic Kidney Disease
Risk of Falling in Chronic Kidney Disease 5
The purpose of this study is to explore the relative importance of the frailty and cardiovascular function as potential exercise-modifiable risk factors for falling in patients receiving haemodialysis.
- Trial name
- NCT02392299
- Where
- 2 sites in United Kingdom
- Volunteers
- 93 people
- Sponsor
- Queen Margaret University
Brain Tumor
Evaluation of Kidney Function in Children With Brain Tumors
Clinical measurement of renal function is generally performed using either laboratory tests or nuclear medicine techniques, however, both of these techniques suffer from some limitations.
- Trial name
- NCT00229801
- Testing
- MRI
- Where
- United States
- Sponsor
- Children's Healthcare of Atlanta
Deceased Donor Kidney Transplant, Acute Kidney Injury
Deceased Donor Biomarkers and Recipient Outcomes
Compared to chronic dialysis, kidney transplantation provides recipients with longer survival and better quality of life at a lower cost.
- Conditions
- Deceased Donor Kidney Transplant, Acute Kidney Injury, Delayed Graft Function, End Stage Renal Disease
- Trial name
- DDS (NCT01848249)
- Where
- 17 sites in United States
- Volunteers
- 1,679 people
- Sponsor
- Yale University
Kidney Transplantation
Use of Sirolimus vs. Tacrolimus For African-American Renal Transplant Recipients
The purpose of this study is to evaluate the efficacy of Sirolimus (Rapamune) in improving the function of the transplant kidney, without any increase in the risk of acute rejection or adverse side effects, compared with…
- Trial name
- NCT00252655
- Testing
- Rapamune and Prograf
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Wayne State University
Renal Insufficiency, Acute
Evaluation of the Renal Function in an Ultra-endurance Race.
During ultra endurance events, athletes experience extreme physical and mental demands, sometimes at the limits of the adaptive response to human physiology.
- Trial name
- INFERNAL (NCT03136315)
- Testing
- INFERNAL Intervention
- Where
- France
- Volunteers
- 54 people, healthy volunteers welcome
- Sponsor
- Central Hospital, Nancy, France
Hyperglycemia, Diabetes
Effects of Hyperglycemia During Cardiopulmonary Bypass on Renal Function
To determine whether intraoperative hyperglycemia potentiates renal injury in the setting of cardiac surgery requiring cardiopulmonary bypass.
- Trial name
- NCT00404950
- Where
- United States
- Volunteers
- 200 people
- Sponsor
- Weill Medical College of Cornell University
Kidney Tumor
Sildenafil Citrate Before Surgery in Improving Kidney Function in Patients With Kidney Cancer
This randomized pilot clinical trial studies sildenafil citrate before surgery in improving kidney function in patients with kidney cancer.
- Trial name
- NCT01950923
- Testing
- sildenafil citrate, therapeutic conventional surgery
- Where
- United States
- Volunteers
- 30 people
- Sponsor
- Wake Forest University Health Sciences
Renal Insufficiency, Healthy
A Study to Assess the Pharmacokinetics, Pharmacodynamics, and Safety of Canagliflozin (JNJ-28431754) in Volunteers With Varying Degrees of Kidney Function
The purpose of this study is to assess the pharmacokinetics (ie, how the body affects the drug) and pharmacodynamics (ie, how the drug affects the body) of canagliflozin (JNJ-28431754) after administration of a single dose to…
- Trial name
- NCT01759576
- Testing
- Canagliflozin (JNJ-28431754)
- Where
- 3 sites in United States
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Sodium, Renal Function
The Effect of Sodium on Erythrocyte Salt Sensitivity, Syndecan-1 and Heparin Sulfate in Healthy Subjects.
The study was a double-blinded, randomized, placebo-controlled cross-over study. 27 healthy subjects received a four days standardized, sodium reduced diet (100 mmol sodium) and treatment with sodium chloride (200 mmol sodium) or…
- Conditions
- Sodium, Renal Function, Blood Pressure
- Trial name
- EGNA (NCT06968182)
- Testing
- Sodium Chloride
- Volunteers
- 27 people, healthy volunteers welcome
- Sponsor
- Frank Mose
Chronic Renal Failure
Relations Between Residual Renal Function and Oxidative and Carbonyl Stress in Peritoneal Dialysis Patients
Residual renal function is reported to contribute to the survival and cardiovascular disease of peritoneal dialysis patients. Oxidative and carbonyl stress are increased in peritoneal dialysis patients and are associated with…
- Trial name
- NCT00692068
- Where
- Japan
- Sponsor
- Iwata City Hospital
Patients Undergoing Liver Transplantation
Impact of %6 HES 130/0.4 and %4 Gelofusine Infusion on Kidney Function in the Living-donor Liver Transplantation
Although the negative impacts of colloid solutions with high molecular weight on renal functions, combination of lower molecular weight colloid varieties with crystalloid solutions and its use during intraoperative period have…
- Trial name
- NCT02079350
- Testing
- %6 HES and %4 Gelofusine
- Where
- Turkey (Türkiye)
- Volunteers
- 36 people
- Sponsor
- Turkiye Yuksek Ihtisas Education and Research Hospital
Bacterial Infections
Pharmacokinetics of Piperacillin and Tazobactam in Critically Ill Patients
Optimal understanding of piperacillin-tazobactam pharmacokinetics in critically ill patients is lacking resulting in large variation of achieved exposure and possible inadequate therapy.
- Trial name
- PICTAR (NCT03738683)
- Testing
- Piperacillin/tazobactam
- Where
- 2 sites in Netherlands
- Volunteers
- 40 people
- Sponsor
- Radboud University Medical Center
Metastatic Kidney Cancer
Impact on Quality of Life, Fatigue and Cognitive Function in Anti-angiogenesis in Patients With Metastatic Kidney Cancer
Longitudinal study nonrandomized, multicenter observational descriptive monitoring patients treated with anti-angiogenic for metastatic kidney cancer
- Trial name
- COG-ANGIO (NCT01336231)
- Where
- 6 sites in France
- Volunteers
- 82 people
- Sponsor
- Centre Francois Baclesse
Renal Alteration
Post-preeclampsia Renal Project: Study of Nephroprotection in Women Having Suffered Preeclampsia
The purpose of the Post-preeclampsia Renal Project is to investigate the renal function of preeclamptic women after delivery, and to determine whether the anti-hypertensive drug named benazepril efficiently improves the…
- Trial name
- RPPEC (NCT01095939)
- Testing
- Benazepril hydrochloride
- Where
- 2 sites in Switzerland
- Volunteers
- 120 people
- Sponsor
- University Hospital, Geneva
Renal Impairment
Effect of Renal Impairment on Evobrutinib Pharmacokinetics (PK)
The study will investigate the PK and safety of evobrutinib in subjects with different degree of renal impairment as compared to subjects with normal renal function.
- Trial name
- NCT03436394
- Testing
- Evobrutinib
- Where
- Germany
- Volunteers
- 31 people, healthy volunteers welcome
- Sponsor
- Merck KGaA, Darmstadt, Germany
Type 2 Diabetes
A Study of HRS9531 in Participants With Impaired Kidney Function and Healthy Subjects
The purpose of this study is to assess how fast HRS9531 gets into the blood stream and how long it takes the body to remove it in participants with impaired kidney function compared to healthy participants.
- Trial name
- NCT06246175
- Testing
- HRS9531
- Where
- China
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Fujian Shengdi Pharmaceutical Co., Ltd.
Kidney Disease
Whole Body Vibration in Kidney Disease
There are no studies in the literature evaluating the vibration of the whole body in patients with chronic renal failure. The study aims to assess the effectiveness of whole body vibration in patients with renal disease in the…
- Trial name
- NCT02413073
- Testing
- Whole Body Vibration
- Volunteers
- 16 people
- Sponsor
- Universidade Federal de Pernambuco
Spinal Stenosis
Effect of Nicardipine on Renal Function in Deliberate Hypotension
The aim of this study was to demonstrate the effect of nicardipine on renal function with creatinine clearance, serum cystatin C, urine output and fractional excretion of sodium during deliberate hypotension for spine surgery.
- Trial name
- NCT02271191
- Testing
- Nicardipine
- Volunteers
- 64 people
- Sponsor
- Yonsei University
Chronic Kidney Diseases, Inspiratory Muscle Training
Effects of Different Inspiratory Muscle Training Protocols in Patients With Chronic Kidney Disease
The goal of this study is to investigate the effects of different IMT protocols on respiratory muscle strength, functional exercise capacity, quadriceps femoris muscle strength (QMS), handgrip muscle strength (HGS), QoL…
- Conditions
- Chronic Kidney Diseases, Inspiratory Muscle Training, Exercise Capacity
- Trial name
- NCT06401135
- Testing
- Inspiratory muscle training
- Where
- Turkey (Türkiye)
- Volunteers
- 47 people
- Sponsor
- Mustafa Kemal University
Advanced Urothelial Cancer, Metastatic Urothelial Cancer
A Study Evaluating Chemotherapy With Fractionated Cisplatin/Gemcitabine Versus Carboplatin/Gemcitabine in the Treatment of Advanced or Metastatic Urothelial Cancer With Impaired Renal Function.
This is a phase II/III, multicenter, randomized study which includes 420 patients on six years + 3 years follow up. 92 patients will be included during the phase II ; additional 328 patients will be included.
- Trial name
- VEFORA (NCT02240017)
- Testing
- Carboplatin, Fractionated Cisplatin, Gemcitabine
- Where
- 18 sites in France
- Volunteers
- 46 people
- Sponsor
- Institut Claudius Regaud
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