Clinical trials: Kinematics
Transtibial Amputation
Metabolic Cost Savings for Transtibial Amputees Wearing the Controlled Energy Storage and Return (CESR) Foot
To determine if below-knee amputees will walk with better efficiency wearing a CESR foot which stores energy at heel strike and releases energy releases energy during push-off.
- Trial name
- NCT00494143
- Testing
- CESR Prosthetic Foot, typical prosthetic foot, standardized prosthetic foot
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs
Knee Prosthesis, Knee Arthroplasty
Comparison of Kinematics for Subjects Implanted With a PFC Sigma Rotating Platform or Fixed Bearing TC3 Prosthesis
The objectives of this study are four-fold: 1. To determine the three-dimensional, in vivo kinematics for subjects having either a fixed- or mobile-bearing Press Fit Condylar (PFC) Sigma Total Condylar III Prosthesis, comparing…
- Trial name
- PFC & TC3 (NCT01290640)
- Testing
- DePuy fixed-bearing Total Condylar III (TC3) TKA, DePuy PFC Rotating Platform TC3 TKA
- Where
- 3 sites in United States
- Volunteers
- 22 people
- Sponsor
- The University of Tennessee, Knoxville
Stroke, Peripheral Neuropathy
Arm Motor Control on Bi and Uni ADLs
This study is being performed to assess how certain chronic disabilities - stroke, upper extremity (UE) amputation, spinal cord injuries (SCI), cerebral palsy (CP) - differ from healthy subjects in their ability to perform ADLs.
- Conditions
- Stroke, Peripheral Neuropathy, Spinal Cord Injuries, Cerebral Palsy
- Trial name
- BiAs (NCT02778529)
- Testing
- Bilateral assessment robots (BiAS)
- Where
- United States
- Volunteers
- 18 people, healthy volunteers welcome
- Sponsor
- University of Pennsylvania
Stroke
Neurophysiological and Kinematic Predictors of Response in Chronic Stroke
The purpose of this study is to design a predictive model of stroke recovery based on baseline measurements of arm movement and brain physiology.
- Trial name
- SRT4 (NCT02658630)
- Testing
- Robot + TTT exercise
- Where
- 2 sites in United States
- Volunteers
- 68 people
- Sponsor
- VA Office of Research and Development
Cough
Respiratory Kinematics During Voluntary and Reflex Cough in Healthy Adults
Cough is a defensive behavior that involves three stages. A large inspiratory phase, a compression phase where the vocal folds close and subglottal pressure is developed, and an expiratory phase.
- Trial name
- NCT01854268
- Testing
- Healthy adults who receive capsaicin
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- University of Florida
Knee Prosthesis, Knee Replacement Arthroplasty
Mechanics Analysis of Patients Having a Sigma Mobile Bearing TKA
Utilize previously developed mathematical model to determine in vivo knee mechanics (kinematics, forces, stresses, areas and sound) for subjects having a Sigma Posterior Stabilizing (PS) mobile bearing (MB) total knee…
- Trial name
- Sigma MB TKA (NCT01714492)
- Testing
- Sigma Posterior Stabilizing Rotating Platform TKA Beaded Poly
- Where
- 3 sites in United States
- Volunteers
- 8 people
- Sponsor
- The University of Tennessee, Knoxville
Traumatic Amputation of Arm
Interface Kinematics of Transhumeral Prosthetic Sockets Using XROMM
The purpose of this pilot study was to conduct a head-to-head comparison of two designs for transhumeral level upper limb prosthetic sockets: a traditional socket design and a socket design hypothesized to provide greater…
- Trial name
- NCT01546675
- Testing
- Skeletal Stabilization
- Where
- 2 sites in United States
- Volunteers
- 2 people
- Sponsor
- US Department of Veterans Affairs
Anterior Knee Pain Syndrome
In Vivo Arthroscopic Behavior of the Infrapatellar Plica of the Knee
Anterior knee pain has been an enigmatic problem for orthopedic surgeons. Recent studies, as well as the clinical observation of the principle investigator have suggested that arthroscopic resection of the infrapatellar plica…
- Trial name
- NCT00643487
- Testing
- observation of the behavior of the infrapatellar plica
- Where
- United States
- Volunteers
- 8 people
- Sponsor
- State University of New York - Upstate Medical University
Stroke
Post Stroke Walking Kinematics Using the Honda Walking Assist Robotic Exoskeleton
To investigate the effect of a robotic exoskeleton on kinematics, muscle activity, ground reaction forces and spatiotemporal characteristics during walking in persons post stroke.
- Trial name
- NCT03828214
- Testing
- Robotic exoskeleton for walking assist
- Where
- United States
- Volunteers
- 11 people
- Sponsor
- College of St. Scholastica, Inc.
Osteoarthritis
Comparison of Knee Kinematics for Subjects Implanted With Either a ConforMIS or Traditional Knee Implant
A better understanding of knee joint kinematics is important to explain the premature polyethylene wear failures within total knee arthroplasties (TKAs) and to help design a prosthesis that most closely approximates the normal…
- Trial name
- NCT01717001
- Where
- 2 sites in United States
- Volunteers
- 66 people
- Sponsor
- Restor3D
Chronic Low Back Pain, Mechanical Low Back Pain
Use of Biofeedback Training to Correct Abnormal Neuromechanical Pattern in Chronic Low Back Pain Patients
The purpose of the present study is to evaluate the benefit of biofeedback training on the capacity of chronic low back pain patients to decrease their lumbar paraspinal muscles activity during trunk full flexion and its…
- Trial name
- NCT02239289
- Testing
- Biofeedback
- Where
- Canada
- Volunteers
- 21 people
- Sponsor
- Université du Québec à Trois-Rivières
Parkinson Disease
Neural and Kinematic Features of Freezing of Gait for Adaptive Neurostimulation
Continuous deep brain stimulation (cDBS) is an established therapy for the major motor signs in Parkinson's disease, however some patients find that it does not adequately treat their freezing of gait (FOG).
- Trial name
- NCT03180515
- Testing
- Activa PC+S Neurostimulator
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
Balance
Villency-Proof of Action: Foot Device, Balance and Sway, Kinematics of Walking
This study involves the use of a newly designed shoe insole device (also referred to as a foot insole device) similar to various shoe insoles or inserts you can buy at a store or pharmacy.
- Trial name
- NCT03663816
- Testing
- experimental foot device
- Where
- United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- University of Florida
Parkinson Disease
Bilateral Closed Loop Deep Brain Stimulation for Freezing of Gait Using Neural and Kinematic Feedback
Deep Brain Stimulation of the subthalamic nucleus (STN) has become a standard of care, FDA-approved treatment for Parkinson's disease, with stimulation delivered at a constant amplitude and voltage, operating in an open-loop…
- Trial name
- NCT04043403
- Testing
- Open Loop DBS, Adaptive (Closed Loop) DBS, Intermittent Open Loop DBS
- Where
- United States
- Volunteers
- 12 people
- Sponsor
- Stanford University
Knee Injuries
Optimized Loading Response by JOURNEY II BCS Knee Increases Daily Physical Activity and Functions
Smith \& Nephew's first edition of the Journey posterior stabilizing total knee arthroplasty was analyzed by the Center for Musculoskeletal Research in a past research study, and it was determined that subjects experienced more…
- Trial name
- NCT02335710
- Testing
- Journey II BCS TKA
- Where
- 3 sites in United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- The University of Tennessee, Knoxville
Stroke, Brain Diseases
Predictors of Response in Chronic Stroke
This study will validate a predictive model that uses demographics, functional status, neurophysiology, neuroanatomy, and other potential biomarkers to predict the likelihood of a clinically significant change in impairment at…
- Conditions
- Stroke, Brain Diseases, Central Nervous System Diseases, Nervous System Diseases
- Trial name
- SRT5 (NCT04283253)
- Testing
- Robot + TTT exercise
- Where
- United States
- Volunteers
- 1 people
- Sponsor
- VA Pittsburgh Healthcare System
Cerebrovascular Accident
Mechanisms of Upper-Extremity Motor Recovery in Post-stroke Hemiparesis
The results of this study will provide sound, scientific evidence of physiologic mechanisms responsible for upper-extremity weakness; evidence of the processes involved in neuromuscular adaptation; and will elucidate the…
- Trial name
- NCT00125658
- Testing
- Control, Experimental
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- VA Office of Research and Development
Arthroplasty, Replacement, Knee, Osteoarthritis, Knee
Knee Kinematics for Subjects With Zimmer-Biomet Posterior Cruciate Retaining or Posterior Stabilizing Total Knee Arthroplasty
25 subjects implanted with a Zimmer-Biomet Posterior Cruciate Retaining (PCR) total knee arthroplasty (TKA) and 25 subjects implanted with a Zimmer-Biomet Posterior Stabilizing (PS) TKA will be asked to perform stepping up and…
- Trial name
- PCR PS TKA (NCT04103515)
- Testing
- Zimmer-Biomet Posterior Cruciate Retaining total knee arthroplasty, Zimmer-Biomet Posterior Stabilizing total knee arthroplasty
- Where
- 3 sites in United States, France
- Volunteers
- 50 people
- Sponsor
- The University of Tennessee, Knoxville
Hip Injuries
THA Kinematics and Sound for Subjects Implanted Using Various Surgical Approaches
In a previous study conducted within the Center for Musculoskeletal Research (CMR) on Total Hip Arthroplasties (THA), it was determined that the investigators could simultaneously capture in vivo sound and motion of the femoral…
- Trial name
- THA (NCT01833481)
- Testing
- Fluoroscopy surveillance of patients while walking
- Where
- 3 sites in United States, Canada
- Volunteers
- 30 people
- Sponsor
- The University of Tennessee, Knoxville
Ankle Arthroplasty, Prosthesis User
3D X-ray Motion Analysis of Ankle-foot Motion After Total Ankle Arthroplasty
Patients who have had a total ankle joint replacement surgery typically have limited movement in their ankles possibly due to the fact that commonly used ankle joint prosthetic devices only allow limited axes of motion.
- Conditions
- Ankle Arthroplasty, Prosthesis User, Joint Disease
- Trial name
- NCT03575975
- Testing
- Total Ankle Replacement Prosthesis
- Where
- United States
- Volunteers
- 9 people, healthy volunteers welcome
- Sponsor
- Georgia Institute of Technology