Clinical trials: Kinetics
Knee Osteoarthritis
The Effect of Training With Custom-Made Biomechanical Perturbation Platform on Kinetics, Kinematics and Electromyography in Knee Osteoarthritis Patients
The aim of this study is to evaluate the outcome of specific repetitive biomechanical perturbation training on motor patterns. The first hypothesis of this project is that footwear derived biomechanical challenges will convey…
- Trial name
- NCT00724139
- Testing
- : APOS biomechanical gait system, Apos - Sports and Medical Technologies Ltd. Hertzlia, Israel
- Where
- Israel
- Volunteers
- 15 people
- Sponsor
- HaEmek Medical Center, Israel
Multiple Sclerosis, Gait Disorders, Neurologic
"Balance, Gait, and Motion Analysis in Multiple Sclerosis"
The goal of this observational cross-sectional study is to investigate the relationship between functional measures of balance and gait and objective kinetic and kinematic parameters in people with Multiple Sclerosis (MS).
- Conditions
- Multiple Sclerosis, Gait Disorders, Neurologic, Postural Balance, Motion Analysis
- Trial name
- MS-BALGAIT (NCT07630311)
- Where
- 2 sites in Greece
- Volunteers
- 40 people
- Sponsor
- University of Patras
Hypercholesterolemia
Effect of Crestor on Lipoprotein Metabolism in Humans
The objective of this research is to understand how Crestor can effectively reduce the levels of the bad cholesterol, LDL, in blood.
- Trial name
- NCT00214617
- Testing
- Rosuvastatin at 5 mg/day and 40 mg/day
- Where
- United States
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- Foundation for Atlanta Veterans Education and Research, Inc.
Healthy
NAD-brain: a Pharmacokinetic Study of NAD Replenishment Therapy
The objective of the NAD-brain study is to determine the blood and brain pharmacokinetics of NAD replenishment therapy (NRT) using Nicotinamide Riboside (NR) or Nicotinamide Mononucleotide (NMN).
- Trial name
- NAD-brain (NCT05698771)
- Testing
- Nicotinamide Riboside (NR), nicotinamide mononucleotide
- Where
- Norway
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- Haukeland University Hospital
Type 1 Diabetes
Dose-effect Relationship of Low-dose IL-2 in Type 1 Diabetes
IL-2 is an inducer of regulatory T cells (Treg), a population of lymphocytes that fail to control the autoimmune destruction of beta-cells in patients with Type 1 Diabetes (T1D).
- Trial name
- DF-IL2 (NCT01353833)
- Testing
- Aldesleukin
- Where
- France
- Volunteers
- 25 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
To Assess the Tissular and Plasma Kinetics of Ertapenem
Prospective, Open-label Study of Pharmacokinetics of Ertapenem in the Muscle Using Microdialysis in Mechanically Ventilated Intensive Care Unit Patients, Treated or Not by Norepinephrine
Goal of study: To assess the tissular and plasma kinetics of ertapenem; To determine the optimal dosages in the patients according to norepinephrine administration: to assess muscular diffusion of free form of ertapenem after…
- Trial name
- NCT00489138
- Testing
- Ertapenem
- Where
- France
- Volunteers
- 9 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Fluid Electrolyte Disorders
Volume Kinetics of Gelofusine 4% During Vascular Surgery
The volume kinetics of the commercially available colloid fluid, Gelofusine 4%, have not been previously studied. Adult patients undergoing open vascular surgery, including femoral and carotid endarterectomy as well as bypass…
- Trial name
- NCT06474052
- Testing
- Gelofusine 4%
- Where
- Romania
- Volunteers
- 15 people
- Sponsor
- Institutul de Urgenţă pentru Boli Cardiovasculare Prof.Dr. C.C. Iliescu
Systemic Sclerosis
89Zr-Oxine-RY_SW01 Cell Injection for the Treatment of Systemic Sclerosis
Systemic sclerosis (SSc) tends to progress to involve multiple vital organs within 5 years of diagnosis, significantly impacting patient prognosis and survival.
- Trial name
- NCT06489652
- Testing
- 89Zr-Oxine-RY_SW01 Cell Injection
- Volunteers
- 8 people
- Sponsor
- Jiangsu Renocell Biotech Company
Acute Myeloid Leukemia
Validation Study of a New Cytokine-based Dynamic Stratification Based on FLt3 Ligand Plasma Concentration Kinetic Profile and IL-6 Concentration During Induction of Acute Myeloid Leukemia
The investigators have recently demonstrated the strong impact in terms of survivals of Fms-like tyrosine kinase 3 ligand (FL) levels evaluated during intensive induction in acute myeloid leukemia (AML) patients.
- Trial name
- FLAMVAL (NCT04641910)
- Testing
- No intervention
- Where
- 25 sites in France
- Volunteers
- 201 people
- Sponsor
- Nantes University Hospital
Adolescent Idiopathic Scoliosis, Gait Disorder, Sensorimotor
The Effect of Conservative Treatment on Gait Biomechanics in Adolescent Idiopathic Scoliosis
Adolescent idiopathic scoliosis (AIS) is a three-dimensional complex progressive structural deformity of the growing spine. Asymmetric changes in both the anatomical structure and strength of the muscles due to deformity affect…
- Trial name
- NCT05577546
- Testing
- Moor S brace treatment, Schroth Three-Dimensional Scoliosis Exercise Treatment
- Where
- Slovenia
- Volunteers
- 45 people, healthy volunteers welcome
- Sponsor
- Medipol University
Prostatic Neoplasms
Effect of Modified Citrus Pectin on PSA Kinetics in Biochemical Relapsed PC With Serial Increases in PSA
To determine if the oral administration of PectaSol-C Modified Citrus Pectin (MCP) is effective at improving Prostate Specific Antigen (PSA) kinetics in men with biochemical relapsed prostate cancer and serial increases in PSA…
- Trial name
- NCT01681823
- Testing
- PectaSol-C Modified Citrus Pectin (MCP)
- Where
- Israel
- Volunteers
- 60 people
- Sponsor
- EcoNugenics
Chronic Lymphocytic Leukemia
Kinetic Biomarker for Chronic Lymphocytic Leukemia Prognosis
This project will attempt to validate the utilization of a stable isotope kinetic biomarker (KineMarkerTM) as a predictive test for disease progression in early stage chronic lymphocytic leukemia (CLL).
- Trial name
- CRC011 (NCT00481858)
- Where
- 5 sites in United States
- Volunteers
- 150 people
- Sponsor
- KineMed
Chronic Myelogenous Leukemia
Nilotinib + Pegylated Interferon Alpha 2a for Untreated Chronic Phase Chronic Myelogenous Leukemia
The aim of this study is to demonstrate the safety and the efficacy of a combination of 2 treatments shown to have some efficacy in Chronic Phase Chronic Myelogenous Leukemia (CP CML) separately, but that have never been combined…
- Trial name
- NILOPEG (NCT01294618)
- Testing
- Nilotinib,Novartis,300 mg twice a day +Pegylated interferon 2a,Roche, 45 microg weekly starting Month 2-Month 12 or beyond according to investigator choice.
- Where
- France
- Volunteers
- 60 people
- Sponsor
- Hospices Civils de Lyon
Nutrition, Healthy
Aminoacidemia and Protein Kinetics in Response to the Ingestion of Plant-based Protein Blends
The present investigation aims to study a novel plant based protein isolate blend to determine if it results in similar muscle building responses compared to whey protein isolate.
- Trial name
- PBP (NCT05139160)
- Testing
- Protein quality
- Where
- Canada
- Volunteers
- 8 people, healthy volunteers welcome
- Sponsor
- McMaster University
Nurses
Comparison of Biomechanics, Function and Pain and Effects of Exercise Intervention Among Nurses
The goal of this study is to compare the effects of exercise interventions (lumbar stabilisation exercise (LSE) versus lumbar muscles strengthening exercises (LMSE)) on full body mechanics, functional disability outcomes and pain…
- Trial name
- NCT05921032
- Testing
- Exercise intervention
- Where
- Malaysia
- Volunteers
- 54 people
- Sponsor
- Universiti Sains Malaysia
Energy Metabolism
Erythrocyte Transport of Lactate During Exercise (TELE Project)
The goals of this clinical trial are: 1. to study lactate kinetic between plasma and erythrocytes during an intervallic exercise and its subsequent recovery, considering the blood pH, the genotype for the T1470A polymorphism of…
- Trial name
- TELE (NCT06104150)
- Testing
- Intervallic submaximal exercise test
- Where
- 2 sites in Spain
- Volunteers
- 84 people, healthy volunteers welcome
- Sponsor
- Technical University of Madrid
Cervical Radiculopathy
Myo-kinetic Stretching Versus Post-isometrics Relaxation Exercise With Traction in Patients of Cervical Radiculopathy
The goal of this clinical trial is to examine the effectiveness of Myo-kinetic stretching exercises versus post-isometric relaxation exercise in patients with cervical radiculopathy.
- Trial name
- NCT05812625
- Testing
- Myokinetic stretching technique, Post Isometric Relaxation
- Where
- Pakistan
- Volunteers
- 68 people
- Sponsor
- Riphah International University
Chronic Non Specific Mechanical Low Back Pain
Effect of Lumbar Stabilization Exercises With and Without YTWL (Scapular Stabilization Exercises) on Reducing Chronic Low Back Pain and Related Disability by Numerical Pain Rating Scale and Modified Oswestry Disability Index Respectively.
Chronic low back pain is a common problem that can make daily activities difficult. Exercises that strengthen and stabilize the lower back are commonly used to reduce pain and improve movement.
- Trial name
- A RCT (NCT07845760)
- Testing
- Lumbar Stabilization Exercises and heating pad, Scapular Stabilization Exercises (YTWL) + Lumbar Stabilization Exercises + Heating Pad
- Where
- Pakistan
- Volunteers
- 70 people
- Sponsor
- Dow University of Health Sciences
Edema Secondary
Infusion Rate and Volume Kinetics for Hyperoncotic Albumine in Healthy Subjects
Treatment with colloidal solutions has during long time been a cornerstone within intensive care. Lately there has been a shift from synthetic colloids to natural albumine.
- Trial name
- (RAV) (NCT03453320)
- Testing
- Albumin solution
- Where
- Sweden
- Volunteers
- 12 people, healthy volunteers welcome
- Sponsor
- University Hospital, Linkoeping
Transtibial Amputation
Metabolic Cost Savings for Transtibial Amputees Wearing the Controlled Energy Storage and Return (CESR) Foot
To determine if below-knee amputees will walk with better efficiency wearing a CESR foot which stores energy at heel strike and releases energy releases energy during push-off.
- Trial name
- NCT00494143
- Testing
- CESR Prosthetic Foot, typical prosthetic foot, standardized prosthetic foot
- Where
- United States
- Volunteers
- 7 people, healthy volunteers welcome
- Sponsor
- US Department of Veterans Affairs