Clinical trials: Knee Arthritis
Knee Osteoarthritis
Therapeutic Exercises for Pain and Disability in Knee Osteoarthritis
This study aims to evaluate the effectiveness of structured therapeutic exercises in reducing pain and disability among older adults diagnosed with knee osteoarthritis.
- Trial name
- OA (NCT07128875)
- Testing
- Exercise + TENS + Hot Pack, Exercise
- Where
- Pakistan
- Volunteers
- 56 people
- Sponsor
- Riphah International University
Osteoarthritis
Study Comparing Fit of the iTotal Versus Standard Total Knee Implants
This study compares intraoperative fit of the patient-specific iTotal knee replacement to other standard knee replacement implants
- Trial name
- NCT01861028
- Where
- United States
- Volunteers
- 44 people
- Sponsor
- Restor3D
Knee Osteoarthritis, Hip Osteoarthritis
Daycase Hip and Knee Arthroplasty in Møre and Romsdal Trial
The DART Study is a prospective, multicentre observational cohort study evaluating day-case pathways for patients undergoing primary total hip arthroplasty, total knee arthroplasty, or unicompartmental knee arthroplasty at three…
- Conditions
- Knee Osteoarthritis, Hip Osteoarthritis, Osteonecrosis, Osteoarthritis
- Trial name
- DART (NCT07834034)
- Testing
- Total Hip Arthroplasty, Total Knee Arthroplasty, Unicondylar knee artrhoplasty
- Where
- 3 sites in Norway
- Volunteers
- 300 people
- Sponsor
- Helse Møre og Romsdal HF
Osteoarthritis of the Knee
Comparative Study of Olive Oil With Piroxicam Gel in Osteoarthritis of the Knee
this is a randomized double blinded trial which is conducted to measure the efficacy of topical virgin olive oil on osteoarthritis of knee that will be done in contrast to standard piroxicam gel.
- Trial name
- NCT00670475
- Testing
- Piroxicam, Olive Oil
- Where
- Iran
- Volunteers
- 60 people
- Sponsor
- Ardabil University of Medical Sciences
Osteoarthritis of the Knee
Platelet Rich Plasma (PRP) as a Treatment for Knee Osteoarthritis PRP as a Treatment for Knee Osteoarthritis
Autologous platelet-secreted growth factors (GFs) may have therapeutic effects in osteoarthritis (OA) capsular joints via multiple mechanisms.
- Trial name
- PRP (NCT01270412)
- Testing
- Platelet Rich Plasma (Preparation Rich in Growth Factors), Hyaluronic acid
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Meir Medical Center
Gonarthrosis
Clinical Outcome and OR Resource Use of Total Knee Arthroplasty Using Patient-Specific or Conventional Instrumentation
Compare OR resource use and clinical Outcome after Total Knee Arthroplasty using Patient-specific or conventional Instrumentation.
- Trial name
- TKA PSI (NCT04114201)
- Testing
- PSI, Conventional
- Where
- 3 sites in Germany
- Volunteers
- 139 people
- Sponsor
- Technische Universität Dresden
Osteoarthritis, Knee
A New Technique to Produce Anatomical Alignment Results With Less Midflexion Instability in Total Knee Arthroplasty
Beside the current standard of classical mechanical alignment of total knee replacements, increased interest is being shown in anatomical alignment.
- Trial name
- NCT02450409
- Testing
- Implantation of TKA using the gap technique, Implantation of TKA using anatomical alignment
- Where
- Germany
- Volunteers
- 56 people
- Sponsor
- University of Jena
Knee Osteoarthritis
Anatomic Relationship Of the Popliteal Vessels In Open Wedge Osteotomy
The Aim Is To Study The Anatomic Relationship Of The Popliteal Vesseles In Two Types Of (OWHTO) Techniques (Monoplanar VS Biplanar) Which Provide More Safe Technique To The PV
- Trial name
- NCT05807451
- Testing
- High Tibial Osteotomy (Uniplanar and Biplanar )
- Where
- Egypt
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- Assiut University
Osteoarthritis
Etude 3000 ARTHROSES Symptomatic Knee and Hip Osteoarthritis Prevalence Survey
Nationwide descriptive epidemiology survey aiming to determine lower limb OA prevalence, based on a validated method previously used to assess inflammatory rheumatism (rheumatoid arthritis and spondylarthropathy) prevalence in…
- Trial name
- 3000ARTHROSE (NCT01400529)
- Where
- 6 sites in France
- Volunteers
- 3,000 people
- Sponsor
- Central Hospital, Nancy, France
Osteoarthritis Knee
Safety and Efficacy of Intra-articular Ozone Injections for Knee Osteoarthritis
Prospective, Interventional, Non-Randomized, Open Label, Single Group Assignment, Single Center.
- Trial name
- NCT02833545
- Testing
- Ozone gas, Steroid injection
- Volunteers
- 50 people
- Sponsor
- Rabin Medical Center
Knee Osteoarthritis
Safety and Efficacy of a Lipiodol Emulsion for the Embolization of Hypervascularizations in Patients With Knee Pain (LipioJoint1)
Knee osteoarthritis is a common cause of disability in patients who are often young and active. Surgery being an option only for the most severe cases, there is little alternative in case of failure of recommended medication.
- Trial name
- LipioJoint1 (NCT04733092)
- Testing
- Lipiodol
- Where
- France
- Volunteers
- 22 people
- Sponsor
- Assistance Publique - Hôpitaux de Paris
Obesity, Osteoarthritis
Surgical Weight-Loss to Improve Functional Status Trajectories Following Total Knee Arthroplasty (SWIFT Trial)
The purpose of the SWIFT Trial is to answer two research questions. 1. Does bariatric surgery before total knee arthroplasty (TKA) improve both perioperative and long-term outcomes of TKA in extreme obesity? 2.
- Trial name
- SWIFT (NCT02598531)
- Where
- United States
- Volunteers
- 289 people
- Sponsor
- Geisinger Clinic
Osteoarthritis, Post-traumatic Arthritis
China ATTUNE® Study
The study was designed as prospective, single-arm, multi-center which was intended to broadly capture all patients as the technology is adopted.
- Trial name
- NCT03542045
- Testing
- Cemented ATTUNE® Knee System
- Where
- China
- Volunteers
- 120 people
- Sponsor
- DePuy Orthopaedics
Osteoarthritis, Knee, Knee Osteoarthritis
A Comparison of Total Knee Replacement Patients Using the Zimmer-Biomet Persona Total Knee System With Different Inserts
As demand for knee joint arthroplasties surge, improving long term patients' satisfaction and implant survivorship has become of utmost importance, as patients seek not only to alleviate their condition, but also return to their…
- Trial name
- NCT04643119
- Testing
- Medial Congruent Insert, Cruciate-Retaining Insert
- Where
- Singapore
- Volunteers
- 120 people
- Sponsor
- Singapore General Hospital
Osteoarthritis, Knee
Comparative Study of Two Hyaluronic Acid Formulation in the Management of Knee Osteoarthritis
The objective of this randomized, double-blind, active-controlled, non-inferiority study is to compare the effectiveness and safety of a single injection of Hymovis ONE®, a sodium hyaluronate formulation, to Monovisc™, another…
- Trial name
- NCT06528600
- Testing
- Hymovis ONE, Monovisc
- Where
- 19 sites in Italy
- Volunteers
- 350 people
- Sponsor
- Fidia Farmaceutici s.p.a.
Knee Osteoarthritis
A Study to Compare Two Rehabilitation Protocols for Knee Osteoarthritis
The aim of this randomized controlled study is to investigate whether the implementation of Blood Flow Restriction, in which the de-loading factor is delivered by the combined progressive de-loaded walking to running activity on…
- Trial name
- NCT05728827
- Testing
- Blood flow restriction training + Anti-gravity treadmill, Anti-gravity treadmill
- Where
- Switzerland
- Volunteers
- 70 people
- Sponsor
- Ente Ospedaliero Cantonale, Bellinzona
Surgery, Knee Osteoarthritis
Bypass PACU in Knee and Hip Arthroplasty
A Quality Study in the use of Post-Anaesthesia Care Unit(PACU) in Hip and Knee Arthroplasty, and the ability to bypass this unit.
- Conditions
- Surgery, Knee Osteoarthritis, Postoperative Complications, Hip Osteoarthritis
- Trial name
- NCT03984942
- Where
- Denmark
- Volunteers
- 600 people
- Sponsor
- Niklas Ingemann Nielsen
Knee Osteoarthritis
Efficacy of Dehydrated Cell and Protein Concentrate Versus Corticosteroid
To compare the efficacy of Ascent injection versus corticosteroid injection in treating knee osteoarthritis.
- Trial name
- NCT03710005
- Testing
- Ascent, Standard
- Where
- 4 sites in United States
- Volunteers
- 51 people
- Sponsor
- StimLabs
Knee Osteoarthritis
Observational Clinical Investigation of Arthrosamid in Knee Osteoarthritis
This is a prospective, long-term, observational, all-comers, open-label, multi-centre clinical investigation enrolling subjects with knee osteoarthritis who is eligible for treatment with Arthrosamid® according to the Instruction…
- Trial name
- LUNA (NCT05057559)
- Where
- 9 sites in Denmark, France and 3 more
- Volunteers
- 201 people
- Sponsor
- Contura
Microdialysis
Clinical Protocol of Sensitized Acupoint Changes in Knee Osteoarthritis Patients
Based on the research background and the preliminary research basis of the research group, in order to answer the material basis and micro-physical environment change characteristics of knee osteoarthritis sensitization acupoints…
- Trial name
- NCT03599180
- Testing
- microdialysis
- Where
- China
- Volunteers
- 33 people, healthy volunteers welcome
- Sponsor
- Chinese Medical Association