Clinical trials: Knee Arthritis Disease
Osteo Arthritis Knee
Tibial and Femoral Components Migration and Adaptive Bone Remodeling After Insertion of Persona® TKA
The purpose of this study: In a prospective randomized study with 2 years of follow-up we want to compare the migration of the uncemented trabecular metal (TM) versus the cemented tibial and femoral components of the new Persona®…
- Trial name
- NCT03563131
- Testing
- Persona® total knee arthroplasty
- Where
- Denmark
- Volunteers
- 66 people
- Sponsor
- Copenhagen University Hospital, Rigshospitalet
Osteoarthritis
Efficacy and Safety Study of Naproxcinod in Subjects With Osteoarthritis of the Knee
To study of efficacy and safety of Naproxcinod vs. Naproxen and Placebo in the indication of signs and symptoms of osteoarthritis
- Trial name
- NCT00504127
- Testing
- Naproxcinod 375 mg bid, Naproxcinod 750 mg bid, Naproxen 500 mg bid
- Where
- 73 sites in United States
- Volunteers
- 1,020 people
- Sponsor
- NicOx
Fangji Huangqi Pill, Knee Osteoarthritis
The Efficacy of the Traditional Chinese Medicine Fangji Huangqi Pill Combined With Mobic on Active Knee Osteoarthritis
Knee osteoarthritis (KOA) is known as degenerative joint disease, which is the most common form of arthritis and the leading cause of disability, loss of function and pain worldwide.
- Trial name
- NCT03173027
- Where
- China
- Volunteers
- 200 people
- Sponsor
- Cui xuejun
Knee Osteoarthritis
Tele-rehabilitation in Knee Osteo Arthritis
Osteoarthritis (OA) is the most common degenerative joint disease with an inflammatory component that starts from the matrix of the articular cartilage.
- Trial name
- NCT06430242
- Testing
- Tele rehabilitation, Exercise
- Where
- Saudi Arabia
- Volunteers
- 56 people
- Sponsor
- Prince Sattam Bin Abdulaziz University
Knee Arthroplasty
Clinical and Economic Comparison of Robot Assisted Versus Manual Knee Replacement
The purpose of this study is to document and compare the surgical and after surgery costs, recovery time, and outcomes of two procedure types: Robotic assisted surgery replacing one compartment of the knee Manual (robot is not…
- Trial name
- NCT01705886
- Testing
- Total Knee Arthroplasty, MAKO® Robot Assisted Medial Knee Arthroplasty, RESTORIS Multicompartmental Knee System
- Where
- United States
- Volunteers
- 62 people
- Sponsor
- Northwest Surgical Specialists, Vancouver
Osteoarthritis
Study to Assess the Efficacy and Safety of Meloxicam vs. Diclofenac SR in Patients With Osteoarthritis of the Knee
To assess the efficacy and safety of meloxicam 7.5mg once daily compared with diclofenac 100mg SR once daily over a treatment period of 8 weeks
- Trial name
- NCT02183129
- Testing
- Diclofenac, Meloxicam
- Volunteers
- 91 people
- Sponsor
- Boehringer Ingelheim
Knee Osteoarthritis
Pain Compared Between the First and the Second Surgery in Staged BTKA
postoperative pain and analgesic consumption between the first and the second surgery would be compared in patients undergoing staged bilateral total knee arthroplasty (BTKA).
- Trial name
- NCT01457313
- Where
- South Korea
- Volunteers
- 34 people
- Sponsor
- Seoul National University Bundang Hospital
Osteoarthritis, Knee
Human Growth Hormone Injections in the Knee Joint to Treat Osteoarthritis
The goal of this clinical trial is to learn if growth hormone injections can be used to treat osteoarthritis (OA) in the knee. Human studies have shown that repeated injections of human growth hormone leads to the production of…
- Trial name
- NCT06354023
- Testing
- Recombinant human growth hormone
- Where
- United States
- Volunteers
- 23 people, healthy volunteers welcome
- Sponsor
- John Sledge
Knee Osteoarthritis, Total Knee Arthroplasty
Improvement of Total Knee Arthroplasty Effectiveness Using Preoperative Prehabilitation
Total knee arthroplasty (TKA) is the most effective treatment for stage III-IV knee osteoarthritis (OA). However, up to 30% of patients remain dissatisfied due to periarticular functional insufficiency, pain, and movement…
- Trial name
- TKA-PREHAB (NCT07790146)
- Testing
- Multimodal phenotype-based prehabilitation
- Where
- Russia
- Volunteers
- 64 people
- Sponsor
- Samara State Medical University
Osteoarthritis, Knee
Diadynamic and Exercises in Knee Osteoarthritis
Osteoarthritis represents failed repair of joint damage resulting from stresses initiated by any joint or periarticular tissue abnormality. The rate of progression varies among persons and within a knee over time.
- Trial name
- NCT05159986
- Testing
- Group that received aplication of Diadynamic currents associated to Exercise during eight weeks with three sessions a week, Group that received exercise during eight weeks with three sessions a week
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- University of Sao Paulo General Hospital
Knee Osteoarthritis
Mobilization With Movement (MWM) on Knee Osteoarthritis (OA)
Movement with mobilization (MWM) is an effective manual therapy to improve pain and function of patients with knee osteoarthritis (OA). However, immediate, and prolonged effects after prolonged MWM period was under-investigated.
- Trial name
- NCT05767788
- Testing
- Movement with Mobilization (MWM)
- Where
- Hong Kong
- Volunteers
- 40 people
- Sponsor
- The Hong Kong Polytechnic University
Knee Osteoarthritis, Total Knee Arthroplasty
Effect of Preoperative Cold Therapy on Early Postoperative Outcomes in Total Knee Arthroplasty
This prospective, single-center, randomized controlled trial investigates the effects of preoperative cold therapy on early postoperative outcomes in patients undergoing unilateral primary total knee arthroplasty (TKA).
- Conditions
- Knee Osteoarthritis, Total Knee Arthroplasty, Cryotherapy, Postoperative Pain Management
- Trial name
- NCT07134283
- Testing
- Preoperative and Postoperative Cold Therapy with Gel Cold Pack, Postoperative Cold Therapy with Gel Cold Pack
- Where
- Turkey (Türkiye)
- Volunteers
- 208 people
- Sponsor
- Ankara City Hospital Bilkent
Knee Osteoarthritis
Comparison of Intermittent Compression-decompression With Glides for Knee Osteoarthritis
the aim of this study is to compare the effects of intermittent compression decompression with glides with conventional physical therapy in patients having knee osteoarthritis.
- Trial name
- NCT05262049
- Testing
- intermittent compression-decompression with glides, Conventional Physical Therapy, conventional physical therapy and intermittent compression-decompression with glides
- Where
- 4 sites in Pakistan
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Riphah International University
Osteoarthritis, Knee
Pain Relief Effect of Low-intensity Continuous Ultrasound Stimulator for Knee Arthritis
The goal of this clinical trial is to test low-intensity continuous ultrasound stimulator(LICUS) for patients suffering from knee arthritis. it aims to evaluate the pain relief effect of LICUS.
- Trial name
- NCT05657535
- Testing
- Low-intensity continuous ultrasound stimulator
- Where
- South Korea
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Kyu Jae Lee
Rheumatoid Arthritis, Health Literacy
Health Literacy, Rational Drug Use, and Cyberchondria in Rheumatic Diseases
Purpose: This study aimed to evaluate rational drug use (RDU), health literacy (HL), and cyberchondria levels among individuals diagnosed with inflammatory rheumatic diseases, and to investigate the factors associated with these…
- Conditions
- Rheumatoid Arthritis, Health Literacy, Rational Drug Use, Cyberchondria
- Trial name
- NCT06993935
- Where
- Turkey (Türkiye)
- Volunteers
- 228 people, healthy volunteers welcome
- Sponsor
- Gulseren Demir Karakilic
Osteoarthritis of the Knee
Safety and Efficacy of Two Dosages of Diractin® in Osteoarthritis (OA)
The purpose of this study is to provide replicated evidence of safety and efficacy of 50 mg and 100 mg ketoprofen in Diractin®.
- Trial name
- NCT00716547
- Testing
- ketoprofen in Diractin®, celecoxib
- Where
- 4 sites in Czechia, Germany and 2 more
- Volunteers
- 1,399 people
- Sponsor
- IDEA AG
Chronic Knee Pain, Osteoarthritis
Sequential Genicular Nerve Ablation Prior to Geniculate Artery Embolization in Knee Pain
The goal of this clinical trial is to evaluate whether performing genicular nerve ablation (GNA) before geniculate artery embolization (GAE) improves pain relief and knee function in patients with chronic knee pain.
- Trial name
- NCT06514755
- Testing
- GNA followed by GAE, GAE alone
- Where
- Egypt
- Volunteers
- 38 people
- Sponsor
- Zagazig University
Knee Osteoarthristis, Osteearthritis
Effects of Diagonal Proprioceptive Neuromuscular Facilitation Patterns on Pain and Functional Outcomes in Patients With Knee Osteoarthritis
A randomized controlled trial will be conducted at the Department of Physiotherapy, Dr. Ziauddin Hospital and Al-Rayaz Hospital, Karachi, Pakistan.
- Conditions
- Knee Osteoarthristis, Osteearthritis, Knee Pain Arthritis
- Trial name
- NCT07396233
- Testing
- Diagonal Proprioceptive Neuromuscular Facilitation (PNF) Pattern Exercises, Conventional Strength Training Exercises, Heat Therapy
- Where
- 2 sites in Pakistan
- Volunteers
- 150 people
- Sponsor
- University of Karachi
Patellofemoral Osteoarthritis
Effect of Hip and Core Muscle Strengthening for Patellofemoral Osteoarthritis: A Feasibility Study
The purpose of this research is to develop and test the feasibility of an exercise intervention for persons with painful knee osteoarthritis involving the patella (kneecap).
- Trial name
- NCT02825238
- Testing
- Supervised exercise program
- Where
- 2 sites in United States
- Volunteers
- 20 people, healthy volunteers welcome
- Sponsor
- University of the Sciences in Philadelphia
Osteoarthritis, X-rays; Effects
SPECT-CT for Assessment of Total Knee Arthroplasty in Navigated and Non-navigated Total Knee Arthroplasty
By the comparison of two operation methods navigated and non-navigated TKR with SPECT/CT we want to show wich method has the better outcome.
- Trial name
- NCT02358447
- Testing
- TKR
- Where
- Switzerland
- Volunteers
- 210 people
- Sponsor
- Kantonsspital Baselland Bruderholz
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