Clinical trials: Knee Extension
Cerebral Palsy
Safety and Performance of Agilik in CP
The purpose of this post market study is to demonstrate the safety and performance of a powered extension assist (EA) knee ankle foot orthosis (KAFO), or EA-KAFO, in individuals with knee extension deficiency due to cerebral…
- Trial name
- Agilik (NCT05746871)
- Testing
- Agilik, standard care
- Where
- Italy
- Volunteers
- 9 people
- Sponsor
- IRCCS Eugenio Medea
Joint (Knee or Hip Replacement)
The Impact of Extending Sleep Before Joint-replacement Surgery on Post-surgical Pain
This study will evaluate the impact of sleep banking on joint replacement surgery recovery.
- Trial name
- NCT07383584
- Testing
- Sleep banking
- Where
- United States
- Volunteers
- 22 people
- Sponsor
- Defense and Veterans Center for Integrative Pain Management
Osteoarthritis
A Study of Pain Relief in Osteoarthritis
The purpose of this study is to compare the safety and pain-relieving ability of Vicodin CR to placebo in subjects with osteoarthritis (OA) of the hip or knee.
- Trial name
- NCT00298974
- Testing
- hydrocodone / acetaminophen extended release
- Where
- 83 sites in United States
- Volunteers
- 873 people
- Sponsor
- Abbott
Knee Injuries
New MRI Measurement of Patellar Height in Knee Extension - IES-EV Control Study
The measurement of the patellar height is essential to decide and quantify the surgical correction to be made. The classic index is that of Cato and Deschamps.
- Trial name
- NCT05659316
- Testing
- MRI imaging
- Where
- France
- Volunteers
- 40 people, healthy volunteers welcome
- Sponsor
- GCS Ramsay Santé pour l'Enseignement et la Recherche
Non-specific Low Back Pain
Dose Response of Neural Mobilization on Hamstring Flexibility in Low Back Pain
This study will be a randomized control trial and will be conducted in Riphah International Hospital, National orthopedic and specialist hospital, Riphah international hospital and Chambeli institute of physiotherapy.
- Trial name
- NCT05101200
- Testing
- High Dose Neural Mobilization Technique, Low Dose Neural Mobilization Technique
- Where
- Pakistan
- Volunteers
- 34 people
- Sponsor
- Riphah International University
Osteoarthritis; Knee
IDEA-033 Three Months Dose Finding in OA Followed by IDEA-033 Three Months Extension in OA
The study objective is the eluciation of the dose-response function in efficacy (and possibly safety) in order to determine an optimal dose with respect to efficacy and safety.
- Trial name
- NCT00316784
- Testing
- IDEA-033 (and rescue medication)
- Volunteers
- 704 people
- Sponsor
- IDEA AG
Hamstring Tightness, Lumbar Lordosis
Hamstring Tightness and Lumbar Lordosis Angel Across Functional Sitting Posture.
The goal of this observational study is to learn about the relationship between hamstring tightness and the lumbar lordosis angle in sedentary adults across different sitting postures.
- Conditions
- Hamstring Tightness, Lumbar Lordosis, Sedentary Behavior, Posture Sitting Position
- Trial name
- LLA-HT (NCT07682142)
- Testing
- Hamstring tightness and lumbar lordosis assessment
- Where
- Egypt
- Volunteers
- 110 people, healthy volunteers welcome
- Sponsor
- Cairo University
Osteoarthritis
Extension Study Of Tanezumab In Osteoarthritis
Safety extension study of Phase 3 Osteoarthritis trials with Tanezumab
- Trial name
- NCT00809783
- Testing
- tanezumab
- Where
- 226 sites in United States
- Volunteers
- 2,147 people
- Sponsor
- Pfizer
Osteoarthitis, Chronic Pain
Efficacy and Safety of Tapentadol Extended Release Tablets in the Treatment of Moderate to Severe Pain in Subjects With Knee Osteoarthritis
The purpose of this study was to examine a low and high dose of tapentadol extended release tablet taken orally twice a day to reduce pain in subjects suffering from chronic moderate to severe pain due to osteoarthritis of the…
- Conditions
- Osteoarthitis, Chronic Pain, Knee Pain
- Trial name
- NCT00745069
- Testing
- tapentadol HCl
- Volunteers
- 670 people
- Sponsor
- Johnson & Johnson Pharmaceutical Research & Development, L.L.C.
Arthritis Knee
Quantitative Assessment of Walking (Squawk) With the Canary canturioTM te (CTE) Tibial Extension
The objective of this prospective study is to demonstrate accuracy of a limp detection model using a healthcare provider assessment as the non-reference standard.
- Trial name
- NCT05693818
- Testing
- Clinical Limping Evalution
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- Canary Medical
Knee Arthropathy
Extended Oral Tranexamic Acid After Primary Total Knee Arthroplasty
This study is a prospective double-blind randomized controlled trial to evaluate the effect of extended oral TXA after primary total TKA on short-term and mid-term postoperative outcomes, including function, pain, and…
- Trial name
- NCT07494032
- Testing
- Tranexamic acid (TXA)
- Where
- United States
- Volunteers
- 350 people
- Sponsor
- NYU Langone Health
Postoperative Pain
Safety and Effectiveness of Tramadex-OD After Knee Arthroscopy
Extended-release tramadol is indicated for the management of moderate to severe pain in adults who require around-the-clock treatment.
- Trial name
- NCT01024348
- Testing
- extended-release tramadol, paracetamol
- Where
- Israel
- Volunteers
- 100 people
- Sponsor
- Shaare Zedek Medical Center
Osteoarthritis of the Knee
An Extension Study of Duloxetine in Osteoarthritis and Knee Pain (Extension of F1J-JE-HMGX, NCT02248480)
The purpose of this study is to assess the safety and efficacy of duloxetine in participants with osteoarthritis and knee pain. The study will last for 1 year.
- Trial name
- NCT02335346
- Testing
- Duloxetine
- Where
- Japan
- Volunteers
- 93 people
- Sponsor
- Eli Lilly and Company
Osteo Arthritis Knee, Pain, Postoperative
Extended Oral Tranexamic Acid After Total Knee Arthroplasty
The utilization of intraoperative tranexamic acid (TXA), whether administered intravenously or orally, has become a standard practice in total joint arthroplasty (TJA).
- Trial name
- NCT06618820
- Testing
- Tranexamic acid
- Where
- United States
- Volunteers
- 120 people
- Sponsor
- Campbell Clinic
Knee Injuries
Electrostimulation in Anterior Cruciate Ligament Reconstruction
The anterior cruciate ligament (ACL) is frequently injured, and it is the structure of the athlete´s knee which has the highest prevalence of reconstruction.
- Trial name
- NCT01633047
- Testing
- electrical stimulation, physical therapy exercises
- Where
- Brazil
- Volunteers
- 24 people, healthy volunteers welcome
- Sponsor
- Federal University of São Paulo
ACL Injury, ACL Tears
Extended Oral Tranexamic Acid After Anterior Cruciate Ligament Reconstruction
This is a prospective, multi-center, randomized, double-blind, placebo-controlled trial evaluating the efficacy of oral tranexamic acid (TXA) in improving postoperative outcomes following anterior cruciate ligament reconstruction…
- Conditions
- ACL Injury, ACL Tears, ACL Surgery
- Trial name
- NCT07115056
- Testing
- Tranexamic Acid (TXA)
- Where
- 6 sites in United States
- Sponsor
- Campbell Clinic
Muscle Stretching
Efficacy of Hamstring Stretching According to the Neural or Muscle Tissue Involvement
Background: Muscle stretching is a technique widely used in the clinical practice of physiotherapy and in the field of sports. In the bibliography we find a multitude of stretches and procedures described, some of them being…
- Trial name
- NCT04763798
- Testing
- Straight-leg-raise (SLR), Passive Knee extension test (PKE), Maximum hip flexion (MHF)
- Where
- Spain
- Volunteers
- 35 people, healthy volunteers welcome
- Sponsor
- Universitat Internacional de Catalunya
Arthropathy of Knee
Economic and Functional Impact of Peri-Operative Bracing for Primary Total Knee Arthroplasty (TKA)
While bracing has been shown to be beneficial for patients with osteoarthritis (OA) in terms of function and strength, whether these unloader braces are also similarly beneficial after total knee arthroplasty (TKA) surgery needs…
- Trial name
- NCT03260699
- Testing
- OCSI Rehabilitator brace
- Where
- United States
- Volunteers
- 9 people
- Sponsor
- The Cleveland Clinic
Arthroplasty
Knee Joint Icing and Knee-extension Strength
With this study the investigators wish to (1) investigate the acute effect of knee joint icing on knee-extension strength shortly after total knee arthroplasty (TKA); and (2) investigate the acute effect of knee joint icing on…
- Trial name
- IS (NCT01249612)
- Testing
- Thermotherapy
- Where
- Denmark
- Volunteers
- 20 people
- Sponsor
- Hvidovre University Hospital
COPD, Muscle Weakness
Feasibility of Strength Training in Patients Hospitalized Due to COPD
To examine the feasibility of progressive unilateral knee-extension strength training using ankle weight cuffs in patients hospitalized due to acute exacerbation in COPD
- Trial name
- NCT01981200
- Testing
- Resistance training in AECOPD
- Where
- Denmark
- Volunteers
- 40 people
- Sponsor
- Frederikssunds Hospital, Denmark