Clinical trials: Knee Osteoarthritis
Knee Osteoarthritis
Circuit Training on Knee Osteoarthritis Patients
Introduction: The increase in intermuscular adipose tissue (IMAT) can contribute to muscle weakness and consequently on progression of knee OA.
- Trial name
- NCT02761590
- Testing
- Circuit training protocol
- Where
- Brazil
- Volunteers
- 60 people
- Sponsor
- Universidade Federal de Sao Carlos
Knee Osteoarthritis
Remote and In-person Supervised Exercise in Patients With Knee Osteoarthritis
Exercise supervision via telehealth resources is an alternative to the in-person modality with similar therapeutic effectiveness across different clinical profiles.
- Trial name
- RISE-KOA (NCT06101797)
- Testing
- Remote supervised exercise group, In-person supervised exercise group
- Where
- Brazil
- Volunteers
- 48 people
- Sponsor
- Federal University of Pelotas
Osteoarthritis, Knee, Postoperative Pain
A Randomized Comparison of the Efficacy of the IPACK Block Versus the Popliteal Plexus Block for Posterior Knee Analgesia, in Patients Undergoing a Total Knee Arthroplasty and Receiving a Continuous Distal Femoral Triangle Block
Total knee arthroplasty (TKA) is commonly associated with significant postoperative pain, including pain arising from the posterior aspect of the knee.
- Trial name
- NCT07876310
- Testing
- Ultrasound-Guided iPACK Block, Ultrasound-Guided Popliteal Plexus Block, Ultrasound-Guided Continuous Femoral Triangle Block
- Volunteers
- 136 people
- Sponsor
- Clinica Santa Maria
Knee Osteoarthristis, Diabetes (DM)
The NTU JO-SMART Study
This study recruits patients with coexisting obesity and knee osteoarthritis (KOA) to implement the NTU-JO Smart Program, an innovative intervention integrating AI-assisted community-based exercise with continuous glucose…
- Conditions
- Knee Osteoarthristis, Diabetes (DM), Obesity & Overweight, Chronic Kidney Disease
- Trial name
- NCT07317310
- Testing
- NTU-JO Smart Program
- Where
- 2 sites in Taiwan
- Volunteers
- 312 people
- Sponsor
- National Taiwan University Hospital
Osteoporosis, Knee Osteoarthritis
Knee Osteoarthritis Outcome Measures in Arthritic Patients With Osteoporosis
The purpose of this study is to generate proof of concept human data by evaluating osteoarthritis outcome measures in arthritic patients that are prescribed Forteo® as the standard of care to treat their primary diagnosis of…
- Trial name
- NCT03217513
- Where
- United States
- Sponsor
- Edward Fox
Osteoarthritis, Osteo Arthritis Knee
Exercise on Knee OA With the Star Excursion Balance Test
Osteoarthritis is a prevalent and disabling condition. Exercise is recommended to maintain strength and mobility, and to decrease pain.
- Trial name
- NCT03450486
- Testing
- exercise
- Where
- Canada
- Volunteers
- 20 people
- Sponsor
- Western University, Canada
Knee Osteoarthritis
Efficacy of Dehydrated Cell and Protein Concentrate Versus Corticosteroid
To compare the efficacy of Ascent injection versus corticosteroid injection in treating knee osteoarthritis.
- Trial name
- NCT03710005
- Testing
- Ascent, Standard
- Where
- 4 sites in United States
- Volunteers
- 51 people
- Sponsor
- StimLabs
Knee Osteoarthritis
Comparison of Single Intra-articular Injection of Hyruan-One With Hylan G-F 20 in Knee Osteoarthritis
We compare the efficacy of intra-articular injection of Hyruan-One with Hylan G-F 20 and placebo (NSS) controlled in a double-blind RCT.
- Trial name
- NCT03484091
- Testing
- Hyruan-One, Hylan G-F 20, Normal saline
- Where
- Thailand
- Volunteers
- 276 people
- Sponsor
- Thammasat University
Osteoarthritis
Clinical Trial of Allogenic Adipose Tissue-Derived Mesenchymal Progenitor Cells Therapy for Knee Osteoarthritis
Evaluate the safety and efficacy of Allogenic Adipose Tissue-Derived Mesenchymal Progenitor Cells Therapy for Knee Osteoarthritis.
- Trial name
- NCT02641860
- Testing
- Mesenchymal progenitor cells
- Where
- China
- Volunteers
- 22 people
- Sponsor
- Shanghai AbelZeta Ltd.
Osteoarthritis, Knee, Hypertension
Staying Active With Arthritis: RCT of Physical Activity for Older Adults With Osteoarthritis and Hypertension
The purpose of the Staying Active with Arthritis (STAR) research study is to determine if a 6-month program will improve leg exercise, fitness walking, and clinical outcomes (function, blood pressure, leg strength, pain, fatigue…
- Trial name
- STAR (NCT01280903)
- Testing
- STAR Intervention, Attention-Control
- Where
- United States
- Volunteers
- 182 people
- Sponsor
- University of Pittsburgh
Osteoarthritis, Knee
Comparative Study of CT and Fluoroscopic Guided Genicular Nerve Ablation in the Treatment of Knee Osteoarthritis
The goal of this study is to evaluate the comparative effectiveness of CT-guided and fluoroscopic-guided genicular nerve ablation in reducing knee pain and improving function in adults diagnosed with knee osteoarthritis…
- Trial name
- NCT06514703
- Testing
- CT-Guided Genicular Nerve Ablation, Fluoroscopic-Guided Genicular Nerve Ablation
- Where
- Egypt
- Volunteers
- 80 people
- Sponsor
- Zagazig University
Knee Arthritis Osteoarthritis
Laser vs Lontophoresis in KOA
This randomized controlled trial aims to compare the effectiveness of laser therapy and iontophoresis in patients with knee osteoarthritis.
- Trial name
- NCT07666061
- Testing
- Low-Level Laser Therapy, Iontophoresis, Conventional Physical Therapy Only
- Volunteers
- 66 people
- Sponsor
- Kafrelsheikh University
Osteoarthritis, Hyperthyroidism
Povidone Iodine Irrıgation at Hip-Knee Arthroplasty
Povidone iodine (PI) solution is an antimicrobial solution that can be used at hip and knee arthroplasty cases. It contains iodine that may be absorbed by the body.
- Conditions
- Osteoarthritis, Hyperthyroidism, Iodine Toxicity
- Trial name
- NCT05599841
- Testing
- PI solution, Saline Solution
- Where
- Turkey (Türkiye)
- Volunteers
- 120 people
- Sponsor
- Ankara University
Osteoarthritis, Knee
A Study of LY2828360 in Patients With Osteoarthritic Knee Pain
To investigate the safety, efficacy and pharmacokinetics of single daily oral dose of LY2828360 in male and female subjects with osteoarthritic knee pain
- Trial name
- NCT01319929
- Testing
- LY2828360
- Where
- Denmark
- Volunteers
- 39 people
- Sponsor
- Eli Lilly and Company
Osteoarthritis, Knee, Myocardial Infarction, Acute
Algarve Active Ageing - Cardiac and Osteoarthritis Rehabilitation (A3-COR)
This study aims to develop, implement, and determines the effectiveness of a personalized medicine approach to each individual's phenotype, based on an innovative physical exercise program to promote the treatment of pain and…
- Conditions
- Osteoarthritis, Knee, Myocardial Infarction, Acute, Hypertension, Dyslipidemias
- Trial name
- A3-COR (NCT05999110)
- Testing
- Physical Exercise
- Where
- Portugal
- Volunteers
- 200 people
- Sponsor
- Associação para o Desenvolvimento do Centro Académico de Investigação e Formação Biomédica do Algarv
Knee Osteoarthritis, Knee Disease
ESPB vs FICB for Pain Management Following Total Hip Prosthesis Surgery
Hip arthroplasty surgery is frequently performed on elderly patients in the community and it is associated with long-term postoperative hospital stays and high mortality.
- Conditions
- Knee Osteoarthritis, Knee Disease, Knee Arthritis
- Trial name
- NCT05621161
- Testing
- Postoperative analgesia management
- Where
- Turkey (Türkiye)
- Volunteers
- 60 people
- Sponsor
- Mursel Ekinci
Pain, Osteoarthritis, Knee
Brief Nurse-led Mindfulness Based Intervention
This is a single-site, two-arm, parallel-group randomized clinical trial (RCT). The feasibility, acceptability, and clinical effects of the nurse-led, very brief, preoperative mindfulness based intervention for hip and knee…
- Conditions
- Pain, Osteoarthritis, Knee, Osteoarthritis, Hip
- Trial name
- NCT04800354
- Testing
- Nurse-led Mindfulness Based Intervention, Nurse-led Pain Psychoeducation
- Where
- United States
- Volunteers
- 127 people
- Sponsor
- University of Utah
Osteoarthritis
Use of Pulsed Electromagnetic Fields for Postoperative Knee Pain
The purpose of this study is to determine whether the Torino II device, which emits a pulsed electromagnetic field), will help to decrease pain and swelling after knee replacement surgery, and thereby decrease the use of narcotic…
- Trial name
- NCT01415856
- Testing
- Active Device (Torino II)
- Where
- United States
- Volunteers
- 40 people
- Sponsor
- Center for Joint Surgery and Sports Medicine, Maryland
Total Knee Replacement
A Study to Compare Different Ways of Steroid Administration After Total Knee Implantation
We are going to evaluate the difference between perioperative intravenous steroid supplementation, perioperative periarticular steroid supplementation, and standard anaesthesia protocols.
- Trial name
- NCT04432012
- Testing
- Dexamethasone Sodium Phosphate 4 mg/ml intravenous, Dexamethasone Sodium Phosphate 4 mg/ml intra-articular
- Where
- Switzerland
- Volunteers
- 159 people
- Sponsor
- Christian Candrian
Osteo Arthritis Knee, Age Related Osteoporosis
Low Frequency Ultrasound for Osteoarthritis Healing and Rehabilitation
The purpose of this study is to determine the safety and effectiveness (how well it works) of a new experimental ultrasound bath device that uses low frequency ultrasound (LFU) that may or may not help healing.
- Conditions
- Osteo Arthritis Knee, Age Related Osteoporosis, Pain, Knee Joint Contracture
- Trial name
- NCT06562374
- Testing
- Low Frequency Ultrasound Therapy
- Where
- United States
- Volunteers
- 10 people
- Sponsor
- The University of Texas Medical Branch, Galveston
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