Clinical trials: Knee Osteoarthritis
Knee Osteoarthritis, Limitation, Mobility
The Effect of Graded Motor Imagery on Pain and Function in Individuals With Knee Osteoarthritis
The aim of this study is to investigate whether Graded Motor Imagery (GMI) application is as effective as Transcutaneous Electrical Nerve Stimulation (TENS) in individuals with knee osteoarthritis (OA).
- Trial name
- NCT05925517
- Testing
- Graded Motor Imagery (GMI), Transcutaneous Electrical Nerve Stimulation (TENS), Conventional Physiotherapy Program
- Where
- Turkey (Türkiye)
- Volunteers
- 46 people, healthy volunteers welcome
- Sponsor
- Artvin Coruh University
Knee Osteoarthritis
Early Progressive Strength Training to Patients With Unicompartmental Knee Replacement
The purpose and Study hypotheses: The purpose of the study is to investigate the effect of progressive resistance training in the early postoperative phase on patients who has had unicompartmental knee replacement.
- Trial name
- NCT01345825
- Testing
- Resistance training
- Where
- Denmark
- Volunteers
- 57 people
- Sponsor
- University of Aarhus
Knee Osteoarthritis
The Effect of Mobilization on Inflammatory Biomarkers in Patients With Knee Osteoarthritis.
This study is designed to investigate whether a hands-on therapy called Mobilization with Movement (MWM) can reduce pain and inflammation in individuals with knee osteoarthritis (OA).
- Trial name
- NCT07166068
- Testing
- Manual Therapy (Mobilization with Movement), Exercise
- Where
- Saudi Arabia
- Volunteers
- 40 people
- Sponsor
- University of Jazan
Osteoarthritis, Knee, Healthy Subjects
Predictors for Analgesic Effect to Standardized Exercise Therapy for Osteoarthritic Pain
Pain sensitization has been associated with pain severity in people with knee osteoarthritis (KOA) and a neuropathic pain component has been identified in up to 30% of KOA patients.
- Trial name
- NCT03718663
- Testing
- Physiotherapy-guided Evidence-based Exercise Therapy, Part 2: Military training
- Where
- Denmark
- Volunteers
- 28 people
- Sponsor
- Kristian Kjær Petersen
Osteoarthritis of the Knee
Structured Treatment of Osteoarthritis of the Knee With or Without Total Knee Replacement
The purpose of this study is to test whether surgical insertion of total knee replacement provides further improvement in quality of life, pain and function in addition to an algorithm for systematic non-surgical treatment…
- Trial name
- MEDIC (NCT01410409)
- Testing
- Neuromuscular training (NEMEX-TJR), Paracetamol, Burana
- Where
- 3 sites in Denmark
- Volunteers
- 100 people
- Sponsor
- Northern Orthopaedic Division, Denmark
Knee Osteoarthritis
Pivotal Clinical Trial to Evaluate the Efficacy and Safety After NPNP-001 Application in Patients with Knee Osteoarthritis.
This study was designed to demonstrate non-inferiority and safety in pain reduction after NPNP-001 application in patients with knee osteoarthritis.
- Trial name
- NCT06779071
- Testing
- NPNP-001, Conjuran
- Where
- South Korea
- Volunteers
- 260 people
- Sponsor
- PharmaResearch Co.,Ltd
Knee Osteoarthritis
Effects of Bracing on Knee Osteoarthritis (OA)
Knee osteoarthritis (OA) is characterized by complaints of knee pain, aching and stiffness that commonly alter the way one will climb stairs and walk reducing an individual's function and the activities they may perform on a…
- Trial name
- NCT01886144
- Testing
- Knee OA Brace
- Where
- United States
- Volunteers
- 25 people, healthy volunteers welcome
- Sponsor
- Stony Brook University
Osteoarthritis
Flavocoxid, A Plant-Derived Therapy, for the Treatment of Knee Osteoarthritis
Nonsteroidal anti-inflammatory drugs (NSAIDs) are commonly prescribed to treat arthritis. The purpose of this study is to test the effectiveness of flavocoxid, a plant-derived compound, for the treatment of knee osteoarthritis…
- Trial name
- NCT00294125
- Testing
- Flavocoxid
- Where
- United States
- Volunteers
- 59 people
- Sponsor
- University of Alabama at Birmingham
Kinesiophobia, Osteo Arthritis Knee
Impact of Breathing and Yoga Poses on Kinesiophobia in Knee Osteoarthritis Patients
The study aimed to determine if deep breathing and conventional physiotherapy were more effective than yoga poses and conventional physiotherapy in reducing kinesiophobia among knee osteoarthritis patients.
- Trial name
- NCT07325032
- Testing
- Deep Breathing exercise, Three typical yoga poses
- Where
- India
- Volunteers
- 40 people
- Sponsor
- Saveetha University
Knee Osteoarthritis
The Efficacy of Exercise and Alternative Applications of NMES on Pain and Function in Patients With Knee OA
The aim of the study was to investigate the efficacy of exercise and different size electrodes of neuromuscular electrical stimulation (NMES) applications on pain, range of motion (ROM), muscle strength, function status and…
- Trial name
- NCT03571698
- Testing
- Neuromuscular Electrical Stimulator
- Volunteers
- 60 people
- Sponsor
- Istanbul University
Osteoarthritis of the Knee
A Study of the Efficacy and Safety of CF101 to Patients With Osteoarthritis of the Knee
This study will test the effectiveness of CF101 in treating the symptoms of osteoarthritis (OA) of the knee. Eligible patients will be given either CF101 or matching placebo tablets and their symptoms will be evaluated over the…
- Trial name
- NCT00837291
- Testing
- CF101
- Where
- Israel
- Sponsor
- Can-Fite BioPharma
Osteoarthritis, Knee, Knee Osteoarthritis
Prospective Functional, Gait, and Outcome Comparison Study of Medial Pivot Versus Single Radius Design for Total Knee Arthroplasty
Patients with degenerative joint disease can effectively be treated with a primary total knee replacement to reduce pain and improve function in their daily lives.
- Conditions
- Osteoarthritis, Knee, Knee Osteoarthritis, Osteoarthritis Knees Both, Osteoarthritis Knee Left
- Trial name
- NCT04814082
- Testing
- MicroPort Evolution Medial-Pivot Knee System (Cruciate-substituting), Stryker Triathlon Tritanium Knee System (Condylar Stabilizing)
- Where
- United States
- Volunteers
- 100 people
- Sponsor
- LifeBridge Health
Osteoarthritis, Knee
Comparison of Surgical Time and Efficiency of Total Knee Arthroplasty
This study is designed to compare the surgical efficiency of TruMatch® Personalized Solutions surgical technique compared to conventional surgical technique.
- Trial name
- NCT01301950
- Testing
- Custom Patient Instrumentation, Conventional Instruments
- Where
- 3 sites in United States
- Volunteers
- 30 people
- Sponsor
- DePuy Orthopaedics
Metalloproteinase SNPs -1575 G/A MMP-2, 836 A/G MMP-9 and -77 A/G MMP-13 and Risk for Developing Knee Osteoarthritis in Greek Population
Association of Single Nucleotide Polymorphisms (SNPs) in Metalloproteinases (MMPs) Genes With the Risk of Primary Knee Osteoarthritis in Greek Population.
Does the presence of gene polymorphisms -1575G / A in the MMP-2 gene, 836A / G in the MMP-9 gene and -77A / G in the MMP-13 gene, affect the risk of developing idiopathic knee osteoarthritis in the Greek population?
- Trial name
- NCT04463290
- Testing
- No intervention, Patients selection based on clinical symptoms and radiological imaging
- Where
- Greece
- Volunteers
- 200 people, healthy volunteers welcome
- Sponsor
- Aristotle University Of Thessaloniki
Osteoarthritis, Knee, Obesity
Effect Of The Use Of Navigation In The Alignment Obtained When Performing A Total Knee Arthroplasty In Obese Patients
NAOBE is a randomized, open and prospective clinical trial that evaluates the accuracy to achieve an adequate mechanical axis of the lower extremity in obese patients after total knee replacement.
- Conditions
- Osteoarthritis, Knee, Obesity, Arthropathy of Knee
- Trial name
- NCT03865524
- Testing
- Total knee arthroplasty implanted with GPS navigation system, Total knee arthroplasty implanted with standard guides.
- Where
- 2 sites in Spain
- Volunteers
- 159 people
- Sponsor
- Pedro-José Torrijos-Garrido
Osteoarthritis
Osteopuncture for Osteoarthritis-Associated Knee Pain & Disability
The purpose of this study is to investigate the feasibility, effectiveness, and duration of treatment response of periosteal electro-acupuncture (osteopuncture) for osteoarthritis (OA)-associated chronic knee pain.
- Trial name
- NCT00417313
- Testing
- periosteal electro-acupuncture (osteopuncture).
- Where
- United States
- Volunteers
- 88 people
- Sponsor
- National Institute on Aging (NIA)
Osteo Arthritis Knee, Joint Diseases
SakuraBead Used as Resorbable Embolic for Genicular Artery Embolization
An open label, prospective, two-arm, multicenter, randomized controlled trial comparing SakuraBead genicular artery embolization (GAE) with a control (corticosteroid injection).
- Conditions
- Osteo Arthritis Knee, Joint Diseases, Musculoskeletal Diseases, Rheumatic Diseases
- Trial name
- SURE (NCT06550024)
- Testing
- SakuraBead Resorbable Microspheres, Corticosteroid Injection
- Where
- 8 sites in United States, Georgia and 2 more
- Volunteers
- 89 people
- Sponsor
- CrannMed
Osteoarthritis, Knee
Effect of Hydrotherapy After Unilateral UKA
Osteoarthritis (OA) is a progressive disease of the synovial joints that causes joint pain and limitation of function resulting in considerable morbidity and impairment of quality of life.
- Trial name
- NCT06459960
- Testing
- Hydrotherapy, Convention
- Where
- Hong Kong
- Volunteers
- 68 people
- Sponsor
- Chinese University of Hong Kong
Knee Osteoarthritis, Osteo Arthritis Knee
Microfragmented Adipose Tissue Compared to Saline Injection for the Treatment of Knee Osteoarthritis
The goal of this clinical trial is to examine the effect of a single autologous, intra-articular injection of MFat versus saline injection for the treatment of pain and function associated with K/L grade 2/3 knee Osteoarthritis.
- Trial name
- ARISE2 (NCT06121882)
- Testing
- Microfragmented Adipose Tissue derived using the Lipogems® System, Saline Injection
- Where
- 16 sites in United States
- Volunteers
- 173 people
- Sponsor
- Lipogems International spa
Osteoarthritis, Knee
Reaching Exercise Goals: Comparison of Exercise Means in Patients With Knee Osteoarthritis
The primary objective is to evaluate water based treadmill exercise, land based treadmill exercise, and upright cycling in meeting American College of Sports Medicine exercise goals for moderate exercise.
- Trial name
- NCT01359124
- Testing
- Exercise Cycle, Land-based Treadmill, Water-based Treadmill
- Where
- United States
- Volunteers
- 60 people
- Sponsor
- Milton S. Hershey Medical Center
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.