Clinical trials: Knee Osteoarthritis
Osteo Arthritis Knee
High Versus Low Adductor Canal Block
The investigators will be comparing the efficacy of two different techniques for performing an adductor canal block to the saphenous nerve as a part of the multimodal pain control regimen for total knee arthroplasty.
- Trial name
- NCT04155983
- Testing
- Ropivacaine
- Where
- United States
- Volunteers
- 140 people
- Sponsor
- Carilion Clinic
Knee Osteoarthritis, Mind-body Exercise
Tai Chi for Knee OA Pain Management: a Mechanistic Study
This study is to determine how 8-week Tai Chi intervention alters plasma endocannabinoid and its receptors in monocytes/marcrophages, plasma oxylipinds, plasma brain-derived neurotrophic factor, brain white matter…
- Trial name
- NCT04046003
- Testing
- Tai chi exercise
- Where
- United States
- Volunteers
- 33 people
- Sponsor
- Texas Tech University Health Sciences Center
Knee Osteoarthritis
Platform Exercise Training
The purpose of this randomized, controlled trial is to determine whether a vibration platform exercise program will be more effective than a standard platform exercise program in improving quadriceps strength in women age 45-60…
- Trial name
- NCT01239823
- Testing
- Whole Body Vibration Training, Exercise without vibration
- Where
- United States
- Volunteers
- 50 people, healthy volunteers welcome
- Sponsor
- University of Iowa
Knee Osteoarthritis
Effects of α MAT Versus Steroid Injection in Knee Osteoarthritis (STα MAT-knee Study)
Knee Osteoarthritis (OA) is a common degenerative knee condition of the knee which is treated symptomatically. Knee cartilage tissue has little regenerative ability With the developments in regenerative medicine, stem cells might…
- Trial name
- NCT04230902
- Testing
- Microfragmented Adipose Tissue Transplant, Corticosteroid injection
- Where
- Lebanon
- Volunteers
- 48 people
- Sponsor
- American University of Beirut Medical Center
Osteoarthritis
The Subvastus Approach in Total Knee Arthroplasty
The purpose of this study is to determine if the observed benefits of minimally invasive total knee arthroplasty, namely decreased hospital stay and increased range of motion, can be achieved with standard knee arthroplasty using…
- Trial name
- NCT00346788
- Testing
- Surgical approach for total knee arthroplasty
- Where
- Canada
- Volunteers
- 126 people
- Sponsor
- Nova Scotia Health Authority
Osteoarthritis
A Study Evaluating the Efficacy of a Single Injection Autologous Adipose Derived Mesenchymal Stromal Cells in Patients With Knee Osteoarthritis
ASCs will be administered via intra-articular use into the knee joint affected by OA where they are expected to exert their therapeutic effects.
- Trial name
- ADIPOA-2 (NCT02838069)
- Testing
- Injection (2x106 ASC/5ml)., Injection (10x106 ASC/5ml).
- Where
- France
- Volunteers
- 100 people
- Sponsor
- University Hospital, Montpellier
Osteoarthritis, Knee
An Evaluation of a Gender Specific Insole to Provide Relief From Knee Pain Due to Osteoarthritis or General Anterior Knee Pain in Male Subjects When Used in Foot Wear Over a Period of Four Weeks
The primary objective of this trial is to demonstrate the ability of a full length foam insole to provide relief from pain due to osteoarthritis of the knee or general knee pain when used in foot wear for a 4-week period of time.
- Trial name
- NCT03556787
- Testing
- BPI 1000013 (Dr Scholls Insole)
- Where
- 2 sites in United States
- Volunteers
- 89 people
- Sponsor
- Bayer
Osteoarthritis, Knee
A Prospective Randomized Trial Using Roentgen Stereophotogrammetric Analysis of the Advance Medial Pivot Knee
The purpose of this study is to determine whether this particular knee replacement is better than those already on the market. By participation, it will further refine the design of future total knee replacements and perhaps…
- Trial name
- NCT00405470
- Testing
- Advance Medial Pivot Knee Arthroplasty
- Volunteers
- 80 people
- Sponsor
- Dalhousie University
Osteoarthritis, Knee
A Proof-of-concept Study to Examine QUC398 in Participants With Knee OA
The purpose of the study was to find out if the investigational treatment named QUC398 had beneficial effects on osteoarthritis (OA) knee pain and knee cartilage, and if it was safe and tolerated.
- Trial name
- NCT05462990
- Testing
- QUC398
- Where
- 14 sites in United States, Australia and 3 more
- Volunteers
- 101 people
- Sponsor
- Novartis Pharmaceuticals
Knee Osteoarthritis
Radio-frequency Ablation in Knee Osteoarthritis by Three Needles Technique
The study is designed to evaluate and compare the efficacy of three needles approach as a new technique in radiofrequency neurotomy of genicular nerve versus the traditional single needle approach as a treatment of advanced knee…
- Trial name
- NCT03613610
- Testing
- Radio-frequency ablation of genicular nerves
- Where
- Egypt
- Volunteers
- 50 people
- Sponsor
- Alaa Fouli Gaber Ebrahim
Osteoarthritis of the Knee
Efficacy and Safety of the Lidoderm Patch Applied to Patients With Osteoarthritis of the Knee
Patients with knee pain due to Osteoarthritis (OA) experiencing sub-optimal pain relief from their current analgesic regimen will participate in a pilot clinical trial to evaluate the effectiveness and tolerability of the…
- Trial name
- NCT00589979
- Testing
- Lidoderm (Lidocaine 5% Patch)
- Where
- 20 sites in United States
- Volunteers
- 169 people
- Sponsor
- Endo USA Inc., a Keenova Therapeutics Company
Knee Osteoarthritis
Therapeutic Effect of the Natural Mineral Water of the Well B-308 OKK in Győr (Gyirmót) on Knee Osteoarthrosis
The main purpose of the study is to investigate the therapeutic effect of the thermal water of Győr (Gyirmót) well No. B-308 OKK on patients with knee arthrosis, and to compare its therapeutic effect with tap water (placebo)…
- Trial name
- NCT06424782
- Testing
- medicinal water
- Where
- Hungary
- Volunteers
- 50 people
- Sponsor
- University of Pecs
Osteoarthrosis of Knee, Osteoarthritis, Knee
Opening Wedge High Tibial Osteotomy
A prospective, randomised controlled trial where clinical and radiological outcome of high tibial opening wedge osteotomy with physiotherapy is compared to physiotherapy alone while treating symptomatic medial knee osteoarthrosis.
- Trial name
- OHTO (NCT03448796)
- Testing
- HTO, Supervised physiotherapeutic program
- Where
- Finland
- Volunteers
- 1 people
- Sponsor
- Kuopio University Hospital
Osteoarthritis, Knee, Osteoarthritis, Hip
Active Video Games for Older Adults With Knee and/or Hip Osteoarthritis.
Population aging is currently an issue of primary relevance, constituting an enormous challenge for institutions and society. On the other hand, osteoarthritis (OA) is the most prevalent arthropathy in the elderly, strongly…
- Trial name
- NCT05839262
- Testing
- Conventional physical rehabilitation plus Active video games (CPR+AVG), Conventional physical rehabilitation alone (CPR)
- Where
- Chile
- Volunteers
- 60 people
- Sponsor
- Cristian Alvarez
Osteoarthritis
Single-use Efficiency Instruments With Patient Specific Technique (MyKnee®) Versus Traditional Metal Instruments With Conventional Surgical Technique
To compare economic factors and the rate of adverse events between two types of instrumentation used for total knee replacement: Single-use Efficiency Instruments with Patient Specific Technique (MyKnee®) Traditional Metal…
- Trial name
- NCT03148379
- Testing
- Customized patient instruments, Traditional Metal Instruments
- Where
- 5 sites in United States
- Volunteers
- 32 people, healthy volunteers welcome
- Sponsor
- Medacta USA
Knee Osteoarthritis
Effect of Energy Restriction and Exercise for Knee Osteoarthritis
The investigators are looking at the effects of energy restriction, with or without exercise on markers of inflammation in individuals with knee osteoarthritis.
- Trial name
- NCT05518890
- Testing
- Diet Only, Diet plus Exercise
- Where
- United Kingdom
- Volunteers
- 32 people
- Sponsor
- University of Bath
Osteoarthritis, Knee Joint Contractures
Creating a Tissue Bank of Knee Capsules
A contracture is a pathological condition limiting range and function of joints. Contractures of large and small joints alike will affect one's ability to independently perform daily activities such as eating, dressing or…
- Trial name
- NCT01320124
- Where
- Canada
- Sponsor
- Ottawa Hospital Research Institute
Knee Osteoarthritis
The Effectiveness of Ultrasound Guided Ozone (O2-O3) Injection With Knee Osteoarthritis
Knee ostheoarthritis (KOA) is a common disabling and degenerative disease leading to painful joints, articular stiffness, and decreased function.
- Trial name
- NCT04830423
- Testing
- Medical ozone injection, steroid injection group
- Where
- Turkey (Türkiye)
- Volunteers
- 96 people, healthy volunteers welcome
- Sponsor
- Gaziler Physical Medicine and Rehabilitation Education and Research Hospital
the Treatment of Knee Osteoarthritis
Comparative Assessment of Intra-articular Knee Injections of Platelet-rich Plasma (PRP) and Hyaluronic Acid in the Treatment of Knee Osteoarthritis
The incidence of cartilage pathology has grown due to the ageing population, and the increase in sports participation and its associated trauma.
- Trial name
- NCT01697423
- Testing
- platelet-rich plasma, durolane
- Where
- France
- Volunteers
- 58 people
- Sponsor
- Assistance Publique Hopitaux De Marseille
Osteoarthritis of the Knee
Autograft Versus Calcium Phosphate Macroporous Bioceramics as Bone Substitute for Tibial Valgus Osteotomy
The aim of the study is to compare radiological behavior of blocks of macroporous phosphocalcium as bone substitute in comparison with iliac crest autograft in tibial valgus osteotomy.
- Trial name
- NCT00200603
- Testing
- calcium phosphate macroporous bioceramics
- Where
- France
- Volunteers
- 50 people
- Sponsor
- Nantes University Hospital
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