Clinical trials: Knee Osteoarthritis
Osteoarthritis
Efficacy of Acupuncture With Physical Therapy for Knee Osteo-Arthritis
This study will examine the efficacy of acupuncture in combination with exercise physical therapy for moderate osteoarthritis (OA) of the knee.
- Trial name
- NCT00035399
- Testing
- Acupuncture
- Where
- 3 sites in United States
- Volunteers
- 300 people
- Sponsor
- National Center for Complementary and Integrative Health (NCCIH)
Osteo Arthritis Knee, Ultrasound Therapy; Complications
Effect of Pulsed Electromagnetic Field and Pulsed Ultrasound in Treating Knee Osteoarthritis
This study will be carried out to combine the effect of PEMF and PUT on pain, function, and ROM in patients with knee OA.
- Trial name
- NCT05151432
- Testing
- Pulsed Ultrasound, Pulsed Electromagnetic field, Traditional exercise program
- Where
- Egypt
- Volunteers
- 80 people, healthy volunteers welcome
- Sponsor
- Horus University
Knee Osteoarthritis, Older Women
Adding Group-Based Pain Neuroscience Education to a Community Exercise Program for Older Women With Knee Osteoarthritis
This pilot trial aimed to estimate preliminary clinical effects and to assess the feasibility of adding group-based pain neuroscience education (PNE) to exercise in women aged ≥60 years with medically diagnosed knee…
- Conditions
- Knee Osteoarthritis, Older Women, Pain, Disability
- Trial name
- NCT07565298
- Testing
- Pain neuroscience education (PNE), Exercise program
- Where
- Chile
- Volunteers
- 19 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Osteoarthritis (OA) of the Knee
Comparison of Effectiveness Between PL and PRP on Knee Osteoarthritis: a Prospective,Randomized,Placebo-controlled Trial
This study will focus on grade I to III knee osteoarthritis by randomized controlled trials which comparing the effectiveness between placebo, autologous platelet rich plasma and autologous platelet lysate injections.
- Trial name
- NCT03734900
- Testing
- Saline injection, PRP injection, PL injection
- Where
- Taiwan
- Volunteers
- 150 people
- Sponsor
- National Taiwan University Hospital
Osteoarthritis
Multi-Center Study to Evaluate the ConforMIS iUni Knee Implant
Study is prospective and multi-center. Study will include 100 to 200 patients across up to 20 sites.The study sites will be located in the United States.The study objective is to evaluate the safety and performance of the…
- Trial name
- iUni (NCT01117571)
- Testing
- iUni® Unicompartmental Knee Resurfacing Device
- Where
- 8 sites in United States
- Volunteers
- 120 people
- Sponsor
- Restor3D
Knee Osteoarthritis, Total Knee Arthroplasty
Intraoperative Direct vs Postoperative Ultrasound Guided Adductor Canal Nerve Block After Total Knee Arthroplasty
This study compares analgesic effect between two techniques of adductor canal nerve block after total knee arthroplasty. The first group of the patients will receive intraoperative adductor canal nerve block; and the other group…
- Conditions
- Knee Osteoarthritis, Total Knee Arthroplasty, Nerve Block
- Trial name
- NCT03733509
- Testing
- Intraoperative Block, Ultrasound Block
- Where
- Chile
- Volunteers
- 121 people
- Sponsor
- Pontificia Universidad Catolica de Chile
Obesity, Overweight
AMAZE 6: A Research Study Investigating How Well the Medicine NNC0487-0111 Helps People With Excess Body Weight and Knee Osteoarthritis Lose Weight and Reduce Pain
This study is being done to look at the safety and effect of NNC0487-0111 in people with excess body weight and knee osteoarthritis when compared to placebo.
- Conditions
- Obesity, Overweight, Osteoarthritis, Knee
- Trial name
- AMAZE 6 (NCT07509307)
- Testing
- NNC0487-0111
- Where
- 81 sites in United States, Australia and 9 more
- Volunteers
- 400 people
- Sponsor
- Novo Nordisk A/S
Osteoarthritis
Comparison of a Single RTX-GRT7039 and Placebo Intra-articular Injection for Pain Associated With Osteoarthritis of the Knee
A double-blind, randomized, placebo-controlled, parallel-group, multi-site, clinical trial to confirm the efficacy and safety of single injection of RTX-GRT7039 versus placebo in patients who have pain associated with…
- Trial name
- NCT05449132
- Testing
- RTX-GRT7039
- Where
- 81 sites in United States, Denmark and 3 more
- Volunteers
- 466 people
- Sponsor
- Grünenthal GmbH
Osteoarthritis, Knee
Autologous Stem Cells in Osteoarthritis
Patients with osteoarthritis, a degenerative joint disease, that meet inclusion criteria will be allocated into two groups: The control group will receive Acetaminophen 750mg orally every 8 hours The experimental group will…
- Trial name
- NCT01485198
- Testing
- Bone Marrow Autologous Stem Cells Infusion, Acetaminophen
- Where
- 2 sites in Mexico
- Volunteers
- 61 people
- Sponsor
- Hospital Universitario Dr. Jose E. Gonzalez
Knee Osteoarthritis
Effects of Hyaluronic Acid Injection and Exercise Treatments in Knee Osteoarthritis
Background: Osteoarthritis (OA) is one of the most common joint diseases that most often causes physical disability. Physical therapy modalities, exercise programs and intra-articular injections are widely used in the treatment…
- Trial name
- NCT06196021
- Testing
- Intra-articular hyaluronic acid injection
- Where
- Turkey (Türkiye)
- Volunteers
- 54 people
- Sponsor
- Balikesir University
Osteoarthritis, Obesity
Multi-parametric Imaging of the Knee in Obese Patients With Knee Osteoarthritis; Weight Loss
This is a substudy to a randomised trial investigating the effect of liraglutide on body weight and pain in overweight or obese patients with knee osteoarthritis (NCT02905864).
- Trial name
- IM-LOSEIT-I (NCT02928471)
- Testing
- Intensive dietary intervention
- Where
- Denmark
- Volunteers
- 200 people
- Sponsor
- Henrik Gudbergsen
Knee Injuries, Knee Osteoarthritis
Walking Gait Biomechanics Following Knee Joint Effusion
The purpose of this study is to determine the sensitivity of a wearable sensor to detect changes in knee joint loading using an experimental knee joint effusion as a model for a common clinical physiological alteration in joint…
- Trial name
- NCT03805464
- Testing
- Knee Joint Effusion
- Where
- United States
- Volunteers
- 14 people, healthy volunteers welcome
- Sponsor
- Duke University
Osteoarthritis, Knee
MRI Markers of Cartilage Damage in Knee With Osteoarthritis
The objectives of this study are: to identify and develop techniques to minimize precision errors in magnetic resonance imaging (MRI) evaluation of knee cartilage, and to determine if results from newly-identified MRI techniques…
- Trial name
- NCT00820430
- Testing
- Magnetic Resonance Imaging
- Where
- 5 sites in United States
- Volunteers
- 53 people, healthy volunteers welcome
- Sponsor
- American College of Radiology
Osteoarthritis, Knee
Effects of Different Telerehabilitation Methods on Pain, Functional Limitation, Muscle Strength, Balance, and Quality of Life in Patients With Knee Osteoarthritis.
The aim of our study is; To compare the effectiveness of asynchronous and synchronous telerehabilitation programs on pain, functional limitation, muscle strength, balance and quality of life parameters in patients with knee…
- Trial name
- NCT05514704
- Testing
- Exercise Therapy via video conference, Exercise Therapy via mobile application
- Volunteers
- 60 people
- Sponsor
- Marmara University
Osteoarthritis, Knee
A Crossover Designed Study to Evaluate Effects of Microcurrent Therapy on Knee Osteoarthritis
This crossover designed study evaluates the effects of microcurrent therapy on knee osteoarthritis. Ín a previous study patients were randomized into four different groups.
- Trial name
- NCT03332914
- Testing
- Microcurrent therapy
- Where
- Germany
- Volunteers
- 13 people
- Sponsor
- Ludwig-Maximilians - University of Munich
Knee Osteoarthritis
Sanomechanics® Rehabilitative Technology
Rehabilitative Sanomechanics Method (RSM) of exercise designed to restore normal subperiosteal transmission of in-joint pressures and normalizing contact pressures on cartilages, will reduce pain in the affected joints and…
- Trial name
- NCT05512507
- Testing
- Physical Therapy Program
- Volunteers
- 15 people
- Sponsor
- PolyOrth International
Knee Osteoarthritis
Steroid Injection vs. BioDRestore for Patients With Knee OA
This study will include patients who are diagnosed with knee OA and are recommended for a knee injection. Study subjects will be randomized to receive either the standard of care knee injection (steroid) or amniotic tissue…
- Trial name
- NCT02767492
- Testing
- BioD Restore, Kenalog
- Where
- United States
- Volunteers
- 90 people
- Sponsor
- The Hawkins Foundation
Osteoarthritis, Knee
Evaluation of Methods of Teaching Self-management Strategies to Patients With Symptomatic Knee Osteoarthritis
Symptomatic knee osteoarthritis greatly impacts the quality of life, mobility, independence, and even safety of the individuals who suffer from it.
- Trial name
- NCT03245463
- Testing
- Educational handout, Verbal script, Hyaluronic Acid
- Where
- United States
- Volunteers
- 24 people
- Sponsor
- Hospital for Special Surgery, New York
Knee Osteoarthritis
Long-Term Follow-up Study of Subjects With Knee Osteoarthritis Who Had Administered FURESTEM-OA Kit Inj. in K0701 Study
Long-Term Follow-up Study of Subjects with Knee Osteoarthritis who had administered FURESTEM-OA Kit Inj. in K0701 study
- Trial name
- NCT06013306
- Volunteers
- 58 people
- Sponsor
- Kang Stem Biotech Co., Ltd.
Knee Osteoarthritis
Oxford UKA and HTO Post-market Clinical Study
The purpose of this study is to compare the performance and safety of medial UKA and HTO in the treatment of AMOA in term of functional outcome, radiographic assessment, range of motion, postoperative complications, revision rate…
- Trial name
- NCT04518111
- Where
- China
- Volunteers
- 370 people
- Sponsor
- Zimmer Biomet
The first 1,020 results can be paged through. Add a filter or change the sort order to reach the rest.