Clinical trials: Knee Osteoarthritis
Chronic Pain, Osteoarthritis, Knee
Embo Registry; National Registry for Artery Embolization
Embo Registry is a retrospective and prospective observational study to evaluate real world effectiveness and the use of Artery Embolization as a treatment for chronic pain with patients that have osteoarthritis and localized…
- Conditions
- Chronic Pain, Osteoarthritis, Knee, Osteoarthritis Thumb, Osteoarthritis Shoulder
- Trial name
- NCT06477965
- Testing
- Artery Embolization
- Where
- 2 sites in United States
- Volunteers
- 1,000 people, healthy volunteers welcome
- Sponsor
- Vascular Solutions of North Carolina
Osteoarthritis
A Migration and Bone Density Study Comparing 2 Types of Bone Cement in the OptiPac Bone Cement Mixing System
The goal of this scientific study is to determine whether there are differences in early migration and prosthesis-near bone density when a standard knee prosthesis is fixed with Refobacin Bone Cement R or with Refobacin Plus Bone…
- Trial name
- NCT00678236
- Testing
- Refobacin Bone Cement R, Refobacin Plus Bone Cement
- Where
- Denmark
- Volunteers
- 54 people
- Sponsor
- University of Aarhus
Osteoarthritis, Knee
Whole-Body Electromyostimulation and Knee Osteoarthritis
The aim of the present study is to evaluate the effects of WB-EMS application in overweight women and men with knee osteoarthritis, with special consideration of sustainability.
- Trial name
- EMSOAT (NCT05672264)
- Testing
- Whole-Body Electromyostimulation, Physiotherapy
- Where
- Germany
- Volunteers
- 72 people
- Sponsor
- University of Erlangen-Nürnberg Medical School
Knee Osteoarthritis
ARTIST: ARThrose Intervention STandardisée
International recommendations (ACR,EULAR) emphasize physical exercise and weight loss for patients suffering from knee osteoarthritis. Nevertheless, number of patients receiving advices for these 2 points still low.
- Trial name
- ARTIST (NCT00462319)
- Testing
- Education, weight reduction and physical exercise
- Where
- France
- Sponsor
- Almirall, SAS
Osteoarthritis, Physical Therapy Modalities
Influence of Using Physical Therapy Resources for Knee Osteoarthritis
Osteoarthritis is a chronic, multifactorial characterization, which changes in bone alignment, cartilage and structures that provide joint stability appear to be strongly correlated with the origin of this disease.This project…
- Trial name
- osteoarthritis (NCT02636764)
- Testing
- exercise, interferential current, short-wave diathermy
- Where
- Brazil
- Volunteers
- 100 people
- Sponsor
- University of Nove de Julho
Knee Osteoarthritis
On-line Neuromuscular Exercise and Education for Knee Osteoarthritis
Due to enforced social distancing as a direct consequence of the COVID-19 pandemic, many on-site health care services are unavailable.
- Trial name
- NCT04437134
- Testing
- On-line exercise and education, On-site exercise and education
- Where
- 4 sites in Denmark
- Volunteers
- 3,789 people
- Sponsor
- Slagelse Hospital
Arthritis;Lumbosacral, Osteo Arthritis Knee
Cooled RF Lesion MRI Characteristics
This Prospective, Single-center, Pilot Study will assist in gaining an understanding of the actual CRFA lesions in an in vivo situation in areas where CRFA is utilized as a standard of care treatment option for the relief of…
- Conditions
- Arthritis;Lumbosacral, Osteo Arthritis Knee, Sacroiliitis, Hip Osteoarthritis
- Trial name
- NCT03631030
- Testing
- Cooled radiofrequency ablation
- Where
- 2 sites in United States
- Volunteers
- 15 people, healthy volunteers welcome
- Sponsor
- International Spine, Pain and Performance Center
Knee Arthropathy, Osteoarthritis, Knee
Investigating the Effectiveness of Vibration Therapy on Sarcopenia in Osteoarthritis Knee Patients
Osteoarthritis (OA) is one of the commonest chronic degenerative conditions affecting our aging population. It limits joint movement and causing disability in elderlies due to discordant symptoms such as pain and stiffness.
- Conditions
- Knee Arthropathy, Osteoarthritis, Knee, Knee Osteoarthritis
- Trial name
- NCT03880344
- Testing
- Vibration Therapy, Physiotherapy
- Where
- Hong Kong
- Volunteers
- 50 people
- Sponsor
- Chinese University of Hong Kong
Knee Osteoarthritis
Evaluation of Femoral Cartilage Thickness After Treadmill and Tartan Track Walking
The aim of this study is to measure and compare the femoral cartilage deformation after walking on the treadmill and tartan floor in patients with knee osteoarthritis (OA) and healthy volunteers.
- Trial name
- NCT05316792
- Testing
- walking
- Volunteers
- 60 people, healthy volunteers welcome
- Sponsor
- Pamukkale University
Osteoarthritis, Knee
Efficacy of Allogeneic UCMSCs for Treating Large Defects Knee Injury
In terms of the surgical treatment of the cartilage injury, various techniques and ways are created to repair or regenerate articular surface of synovial joint following traumatic damage or degeneration of the cartilage.
- Trial name
- NCT05016011
- Testing
- Human umbilical cord-derived mesenchymal stem cells (hUC-MSCs), Marrow cellution
- Where
- Malaysia
- Volunteers
- 28 people
- Sponsor
- Cytopeutics Sdn. Bhd.
Knee Osteoarthritis
Effectiveness of Radial Extracorporeal Shock Wave Therapy in Patients With Knee Osteoarthritis
Osteoarthritis (OA) is a degenerative joint disease characterized by unsuccessful repair of joint damage resulting from stresses in any of the synovial joint tissues.
- Trial name
- NCT06281444
- Testing
- ESWT
- Where
- Turkey (Türkiye)
- Volunteers
- 72 people
- Sponsor
- Ankara University
Knee Osteoarthritis
Cryoneurolysis Versus Radiofrequency in Knee Osteoarthritis
The project will evaluate the effectiveness of Cryoneurolysis versus radiofrequency procedures in adult patients who are resistant to traditional treatment for knee pain. They are a drug-free pain management procedure.
- Trial name
- NCT07664371
- Testing
- Cryoneurolysis, pulsed radiofrequency (RF), cooled radiofrequency
- Where
- Egypt
- Volunteers
- 30 people
- Sponsor
- Tanta University
Exercise Therapy, Osteoarthritis Of Knee
Biofeedback With Cycling Exercise in OA Knee Patients
Osteoarthritis (OA) is one of the most common joint diseases causing pain, muscle weakness and disability in older population. Quadriceps muscle weakness is one of the recognized risk factors for the development and the…
- Conditions
- Exercise Therapy, Osteoarthritis Of Knee, Biofeedback
- Trial name
- NCT03484910
- Testing
- Exercise therapy
- Where
- Taiwan
- Volunteers
- 23 people
- Sponsor
- China Medical University Hospital
Osteoarthritis, Knee, Chronic Pain
Understanding Pain Mechanisms in Knee Osteoarthritis
UP-KNEE study is a feasibility, double-blind, placebo-controlled randomised parallel study in participants with radiographically defined knee OA, and with self-reported chronic knee pain.
- Trial name
- UP-KNEE (NCT05561010)
- Testing
- Intra-articular injection of bupivacaine in the knee joint
- Volunteers
- 50 people
- Sponsor
- Nottingham University Hospitals NHS Trust
Osteoarthritis, Knee
Study on Structum® in Adult Patients With Osteoarthritis (TRUST)
Chondroitin sulfate (CS) is a Symptomatic Slow Acting Drugs for OsteoArthritis (SYSADOA) and a natural biomacromolecule belonging to the class of glycosaminoglycans.
- Trial name
- TRUST (NCT06623773)
- Testing
- Chondroitin sulfate
- Where
- 15 sites in Poland
- Volunteers
- 136 people
- Sponsor
- Pierre Fabre Medicament
Knee Osteoarthritis
Assessment of Safety and Efficacy of ARTHRUM 2.5% for Treatment of Painful Osteoarthritis of the Knee
ARTHRUM 2.5% MONO-INJECTION as symptomatic treatment by joint injection extends the conservative therapeutic arsenal in Knee osteoarthritis.
- Trial name
- ART-ONE75 (NCT06228274)
- Testing
- ARTHRUM 2.5%
- Volunteers
- 218 people
- Sponsor
- LCA Pharmaceutical
Knee Osteoarthritis
The Effectiveness of Different Doses of Hyaluronic Acid Injections in Knee Osteoarthritis.
The aim of this prospective, randomized, controlled multi-centre study is to compare the effectiveness and safety of three and five injections of standard linear hyaluronic acid (HA) versus single HA injection in terms of pain…
- Trial name
- NCT04786613
- Testing
- Intra-articular 20 mg, 1.0% Hyaluronic Acid Injection, Intra-articular 32 mg, 1.6% Hyaluronic Acid Injection, Intra-articular 48 mg, 2.0% Hyaluronic Acid Injection
- Where
- Turkey (Türkiye)
- Volunteers
- 100 people
- Sponsor
- Istanbul University
Post-traumatic Osteoarthritis, Knee Sprain
Efficacy of an Evidence-based Telehealth Intervention in Modifying Health Behavior
The overall objective of this study is to evaluate the efficacy of the mare telehealth intervention platform and the intervention on patients' readiness to manage osteoarthritis and patient reported outcomes.
- Conditions
- Post-traumatic Osteoarthritis, Knee Sprain, Knee Injuries
- Trial name
- MIRROR_14 (NCT07187024)
- Testing
- mCare PTOA Intervention
- Where
- United States
- Volunteers
- 65 people
- Sponsor
- Keller Army Community Hospital
Osteoarthritis
Study to Assess Exactech's Guided Personalized Surgery eGPS® in Total Knee Arthroplasty
Study to collect outcomes data for patients who are undergoing an Exactech Optetrak® primary total knee replacement using the Exactech Guided Personalized Surgery (eGPS®) manufactured or distributed by (Exactech, Gainesville…
- Trial name
- NCT02962362
- Where
- United States
- Volunteers
- 73 people
- Sponsor
- Exactech
Osteoarthritis, Knee
Effect of Transcutaneous Electrostimulation (TENS) on Pain and Physical Function in Patients With Knee Osteoarthritis
The proposed study is a multi-center, randomized, double blind (patient and assessor), sham controlled clinical trial using a parallel 2 group design recruiting 220 patients of at least 18 years of age.
- Trial name
- ETRELKA (NCT01875042)
- Testing
- TENS
- Where
- Switzerland
- Volunteers
- 220 people
- Sponsor
- Insel Gruppe AG, University Hospital Bern
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